CN105614102A - Pig feed additive for improving immunity and improving intestinal health - Google Patents
Pig feed additive for improving immunity and improving intestinal health Download PDFInfo
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Abstract
The invention provides a pig feed additive for improving immunity and improving intestinal health, and belongs to the field of feed additives. The additive is prepared from Chinese herbal medicine, plant polysaccharides, microbial ecological agents, vitamins, mineral substances and carriers. The carriers are degreased rice bran and bran. By means of the additive, the immunity of pigs can be effectively improved, the morbidity of pigs can be decreased, and antibiotics and chemical synthesized medicine can be replaced or partially replaced. In addition, by means of the additive, the intestinal health of pigs can be improved, the diarrhea rate can be decreased, the feed conversion rate can be increased, and important significance in promoting healthy development of feed and the animal husbandry, improving breeding benefits and lowering breeding risks is achieved.
Description
Technical field
The present invention relates to a kind of pig's feed additive, especially relate to a kind of pig's feed additive improving immunizing power and improve intestinal health, belong to feed additive field.
Background technology
In recent years, because antibiotics fodder additives abuse, the food-safety problem that causes appears in the newspapers again and again, and thus cause directly and indirect economic loss number is huge makes people startling, the environmental problem thus brought in addition also should not be underestimated. Microbiotic has can not by the characteristic of the complete metabolism of humans and animals body, it is discharged to external by ight soil mainly with the form of original shape and active metabolite greatly, through a series of biotransformations such as absorption, photodissociation, hydrolysis and microbiological deteriorations, the direct influence ecological environment of meeting, remote effect HUMAN HEALTH. Swine disease cultivates maximum risk simultaneously, and reducing pig sickness rate is the big difficult problem being difficult in aquaculture break through, and seriously governs the development of pig industry.
The enteron aisle of pig is the main place that food digestion absorbs, and the healthy growth maintaining pig is had important effect. At enteron aisle, the various nutritive substances in chyme are broken down into various small-molecule substance, absorb through enteron aisle fine hair and enter blood and lymph, utilize for body each several part. In addition, in the defence process of body, enteron aisle also plays an important role. Improve pig intestinal health, be conducive to improving feed digestibility, it is to increase the use value of feed, the immunizing power of pig can also be strengthened, on the positive impact of growing of pig simultaneously.
Therefore the little additive of a kind of natural, nutrition, toxic side effect is developed important to what improve the immunizing power of pig and improve that pig intestinal health seems particularly; the use of microbiotic can not only be reduced; protection human health; pig sickness rate can also be reduced; reduce cultivation risk; be conducive to promoting feed and the healthy and orderly development of herding industry, to raising culture benefit, reduce cultivation risk significant.
Summary of the invention
It is an object of the invention to provide a kind of pig's feed additive improving immunizing power and improve intestinal health. This additive can effectively improve the immunizing power of pig, reduces the sickness rate of pig, can substitute or the use of Some substitute microbiotic and chemosynthesis class medicine. In addition, this additive can also improve the intestinal health of pig, reduces diarrhea rate, it is to increase feed conversion rate, for the sound development promoting feed and livestock industry, it is to increase culture benefit, reduces cultivation risk significant.
The technical solution adopted for the present invention to solve the technical problems is as follows:
Improving immunizing power and improve a pig's feed additive for intestinal health, every 100 parts are made up of following raw materials by weight portion:
Vervain 3-5 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 3-5 part, Rhizome of Grass leaf Sweelflag 3-4 part, Root of Racemose Inula 1-2 part, Howthorn Leaf 2-4 part, Herba Centellae 1-2 part, carrot pomace 1-2 part, Aloe polysaccharide 0.5-1 part, probiotics 1-2 part, vitamins C 0.1-0.3 part, vitamins B10.1-0.2 part, vitamins D30.1-0.2 part, ��-carotene 0.1-0.2 part, calcium lactate 0.5-0.8 part, ferrous citrate 0.2-0.5 part, rose vitriol 0.1-0.2 part, all the other are carrier, carrier by defatted rice bran and wheat bran in mass ratio 2:1 form, defatted rice bran and wheat bran are pre-mixed pulverized 60 orders sieves.
The preparation method of described vervain is: vervain was pulverized 60 orders and sieves and get final product;
The preparation method of described Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) is: Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) was pulverized 60 orders and sieves and get final product;
The preparation method of described Rhizome of Grass leaf Sweelflag is: Rhizome of Grass leaf Sweelflag was pulverized 60 orders and sieves and get final product;
The preparation method of described Root of Racemose Inula is: Root of Racemose Inula was pulverized 60 orders and sieves and get final product;
The preparation method of described Howthorn Leaf is: Howthorn Leaf was pulverized 60 orders and sieves and get final product;
The preparation method of described Herba Centellae is: Herba Centellae was pulverized 60 orders and sieves and get final product.
The preparation method of described carrot pomace is:
(1) fresh Radix Dauci Sativae is cleaned with distilled water, chopping, it is placed in air dry oven and dries so that it is moisture is lower than 10%, and bake out temperature is 60-65 DEG C;
(2) Radix Dauci Sativae after oven dry was pulverized 60 orders sieves, obtained carrot pomace.
The preparation method of described Aloe polysaccharide is:
(1) being cleaned by fresh aloe distilled water, peeling, chopping, is placed in container;
(2) by solid-to-liquid ratio 1:(10-20) in container, add distilled water, boiling 20-30min at 85-95 DEG C of temperature, then boiling 3-5h at 60-70 DEG C of temperature, filter after boiling, get filtrate;
(3) filtrate is dried at 65-70 DEG C of temperature, obtain powdery solid;
(4) powdery solid was pulverized 60 order sieves, obtained Aloe polysaccharide.
Described probiotics by lactobacillus reuteri, bifidobacterium breve, lactobacterium casei and slow genus bacillus by bacteria suspension volume ratio 1:1:(1-3): (2-3) mixes; Wherein, lactobacillus reuteri bacteria suspension concentration is 1.5 �� 106Individual/ml, bifidobacterium breve bacteria suspension concentration is 2.0 �� 107Individual/ml, lactobacterium casei bacteria suspension concentration is 2.5 �� 106Individual/ml, slow genus bacillus bacteria suspension concentration is 2.1 �� 107Individual/ml.
Improving immunizing power and improve a pig's feed additive for intestinal health, the addition in pig feed is 100-300g/t.
The useful effect of the present invention:
There is between herbal medicine in the present invention good coordinative role, can effectively improve immunizing power and improve intestinal health. Aloe polysaccharide adopts specific method to prepare, and by optimizing Extracting temperature, can obtain more excellent Aloe polysaccharide.
Fodder additives compatibility science in the present invention, can effectively improve the immunizing power of pig, reduces pig sickness rate, the use in feed such as minimizing microbiotic. In addition, this additive can also improve pig intestinal health, promote that pig is to the eupepsy of feed, accelerate pig growth, and this additive main component is all natural product, there is the features such as safety, nutrition, toxic side effect are little, be conducive to promoting feed and the healthy and orderly development of livestock industry, human health is had positive effect, belongs to the fodder additives of green safety.
Specific embodiment
The present invention is further described below by way of specific embodiment.
Embodiment 1: a kind of pig's feed additive improving immunizing power and improve intestinal health, every 100 parts are made up of following raw materials by weight portion: vervain 3 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 3 parts, Rhizome of Grass leaf Sweelflag 3 parts, Root of Racemose Inula 1 part, Howthorn Leaf 2 parts, Herba Centellae 1 part, carrot pomace 1 part, Aloe polysaccharide 0.5 part, probiotics 1 part, vitamins C 0.1 part, vitamins B10.1 part, vitamins D30.1 part, ��-carotene 0.1 part, calcium lactate 0.5 part, ferrous citrate 0.2 part, rose vitriol 0.1 part, all the other are carrier, carrier by defatted rice bran and wheat bran in mass ratio 2:1 form, defatted rice bran and wheat bran are pre-mixed pulverized 60 orders sieves.
The preparation method of described vervain is: vervain was pulverized 60 orders and sieves and get final product;
The preparation method of described Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) is: Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) was pulverized 60 orders and sieves and get final product;
The preparation method of described Rhizome of Grass leaf Sweelflag is: Rhizome of Grass leaf Sweelflag was pulverized 60 orders and sieves and get final product;
The preparation method of described Root of Racemose Inula is: Root of Racemose Inula was pulverized 60 orders and sieves and get final product;
The preparation method of described Howthorn Leaf is: Howthorn Leaf was pulverized 60 orders and sieves and get final product;
The preparation method of described Herba Centellae is: Herba Centellae was pulverized 60 orders and sieves and get final product.
The preparation method of described carrot pomace is:
(1) fresh Radix Dauci Sativae is cleaned with distilled water, chopping, it is placed in air dry oven and dries so that it is moisture is lower than 10%, and bake out temperature is 60 DEG C;
(2) Radix Dauci Sativae after oven dry was pulverized 60 orders sieves, obtained carrot pomace.
The preparation method of described Aloe polysaccharide is:
(1) being cleaned by fresh aloe distilled water, peeling, chopping, is placed in container;
(2) in container, add distilled water by solid-to-liquid ratio 1:10, boiling 20min at 85 DEG C of temperature, then boiling 3h at 60 DEG C of temperature, filter after boiling, get filtrate;
(3) filtrate is dried at 65 DEG C of temperature, obtain powdery solid;
(4) powdery solid was pulverized 60 order sieves, obtained Aloe polysaccharide.
Described probiotics is mixed by bacteria suspension volume ratio 1:1:1:2 by lactobacillus reuteri, bifidobacterium breve, lactobacterium casei and slow genus bacillus; Wherein, lactobacillus reuteri bacteria suspension concentration is 1.5 �� 106Individual/ml, bifidobacterium breve bacteria suspension concentration is 2.0 �� 107Individual/ml, lactobacterium casei bacteria suspension concentration is 2.5 �� 106Individual/ml, slow genus bacillus bacteria suspension concentration is 2.1 �� 107Individual/ml.
Improving immunizing power and improve a pig's feed additive for intestinal health, the addition in pig feed is 100g/t.
Embodiment 2: a kind of pig's feed additive improving immunizing power and improve intestinal health, every 100 parts are made up of following raw materials by weight portion: vervain 5 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5 parts, Rhizome of Grass leaf Sweelflag 4 parts, Root of Racemose Inula 2 parts, Howthorn Leaf 4 parts, Herba Centellae 2 parts, carrot pomace 2 parts, Aloe polysaccharide 1 part, probiotics 2 parts, vitamins C 0.3 part, vitamins B10.2 part, vitamins D30.2 part, ��-carotene 0.2 part, calcium lactate 0.8 part, ferrous citrate 0.5 part, rose vitriol 0.2 part, all the other are carrier, carrier by defatted rice bran and wheat bran in mass ratio 2:1 form, defatted rice bran and wheat bran are pre-mixed pulverized 60 orders sieves.
The preparation method of described vervain is: vervain was pulverized 60 orders and sieves and get final product;
The preparation method of described Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) is: Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) was pulverized 60 orders and sieves and get final product;
The preparation method of described Rhizome of Grass leaf Sweelflag is: Rhizome of Grass leaf Sweelflag was pulverized 60 orders and sieves and get final product;
The preparation method of described Root of Racemose Inula is: Root of Racemose Inula was pulverized 60 orders and sieves and get final product;
The preparation method of described Howthorn Leaf is: Howthorn Leaf was pulverized 60 orders and sieves and get final product;
The preparation method of described Herba Centellae is: Herba Centellae was pulverized 60 orders and sieves and get final product.
The preparation method of described carrot pomace is:
(1) fresh Radix Dauci Sativae is cleaned with distilled water, chopping, it is placed in air dry oven and dries so that it is moisture is lower than 10%, and bake out temperature is 65 DEG C;
(2) Radix Dauci Sativae after oven dry was pulverized 60 orders sieves, obtained carrot pomace.
The preparation method of described Aloe polysaccharide is:
(1) being cleaned by fresh aloe distilled water, peeling, chopping, is placed in container;
(2) in container, add distilled water by solid-to-liquid ratio 1:20, boiling 30min at 95 DEG C of temperature, then boiling 5h at 70 DEG C of temperature, filter after boiling, get filtrate;
(3) filtrate is dried at 70 DEG C of temperature, obtain powdery solid;
(4) powdery solid was pulverized 60 order sieves, obtained Aloe polysaccharide.
Described probiotics is mixed by bacteria suspension volume ratio 1:1:3:3 by lactobacillus reuteri, bifidobacterium breve, lactobacterium casei and slow genus bacillus; Wherein, lactobacillus reuteri bacteria suspension concentration is 1.5 �� 106Individual/ml, bifidobacterium breve bacteria suspension concentration is 2.0 �� 107Individual/ml, lactobacterium casei bacteria suspension concentration is 2.5 �� 106Individual/ml, slow genus bacillus bacteria suspension concentration is 2.1 �� 107Individual/ml.
Improving immunizing power and improve a pig's feed additive for intestinal health, the addition in pig feed is 300g/t.
Embodiment 3: a kind of pig's feed additive improving immunizing power and improve intestinal health, every 100 parts are made up of following raw materials by weight portion: vervain 4 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 4 parts, Rhizome of Grass leaf Sweelflag 3.5 parts, Root of Racemose Inula 1.5 parts, Howthorn Leaf 3 parts, Herba Centellae 1.5 parts, carrot pomace 1.5 parts, Aloe polysaccharide 0.8 part, probiotics 1.5 parts, vitamins C 0.2 part, vitamins B10.15 part, vitamins D30.15 part, ��-carotene 0.15 part, calcium lactate 0.6 part, ferrous citrate 0.4 part, rose vitriol 0.15 part, all the other are carrier, carrier by defatted rice bran and wheat bran in mass ratio 2:1 form, defatted rice bran and wheat bran are pre-mixed pulverized 60 orders sieves.
The preparation method of described vervain is: vervain was pulverized 60 orders and sieves and get final product;
The preparation method of described Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) is: Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) was pulverized 60 orders and sieves and get final product;
The preparation method of described Rhizome of Grass leaf Sweelflag is: Rhizome of Grass leaf Sweelflag was pulverized 60 orders and sieves and get final product;
The preparation method of described Root of Racemose Inula is: Root of Racemose Inula was pulverized 60 orders and sieves and get final product;
The preparation method of described Howthorn Leaf is: Howthorn Leaf was pulverized 60 orders and sieves and get final product;
The preparation method of described Herba Centellae is: Herba Centellae was pulverized 60 orders and sieves and get final product.
The preparation method of described carrot pomace is:
(1) fresh Radix Dauci Sativae is cleaned with distilled water, chopping, it is placed in air dry oven and dries so that it is moisture is lower than 10%, and bake out temperature is 62 DEG C;
(2) Radix Dauci Sativae after oven dry was pulverized 60 orders sieves, obtained carrot pomace.
The preparation method of described Aloe polysaccharide is:
(1) being cleaned by fresh aloe distilled water, peeling, chopping, is placed in container;
(2) in container, add distilled water by solid-to-liquid ratio 1:15, boiling 25min at 90 DEG C of temperature, then boiling 4h at 65 DEG C of temperature, filter after boiling, get filtrate;
(3) filtrate is dried at 68 DEG C of temperature, obtain powdery solid;
(4) powdery solid was pulverized 60 order sieves, obtained Aloe polysaccharide.
Described probiotics is mixed by bacteria suspension volume ratio 1:1:2:2.5 by lactobacillus reuteri, bifidobacterium breve, lactobacterium casei and slow genus bacillus; Wherein, lactobacillus reuteri bacteria suspension concentration is 1.5 �� 106Individual/ml, bifidobacterium breve bacteria suspension concentration is 2.0 �� 107Individual/ml, lactobacterium casei bacteria suspension concentration is 2.5 �� 106Individual/ml, slow genus bacillus bacteria suspension concentration is 2.1 �� 107Individual/ml.
Improving immunizing power and improve a pig's feed additive for intestinal health, the addition in pig feed is 200g/t.
Test example:
1, experimental animal and test design
Test and Selection 160 subordinate plant of twins (group) limited-liability company mean body weights are " Du Chang great " tri-crossbreeding of about 28kg, it is divided into 4 groups at random, often organizing 4 repetitions, each repeats 10 pigs (male and female half and half), comprising a blank group and 3 test group. Blank group swine rations does not add any raising immunizing power obtained in embodiment 1-3 and improves the pig's feed additive of intestinal health, the additive that in all the other 3 test group swine rationses, additive embodiment 1-3 is obtained respectively, live pig free choice feeding and drinking-water, carrying out immunity and expelling parasite routinely, in trial period, every day observes and records the mental status of porcine influenza situation and pig. 90 days trial periods. In feeding process, each group of pig incidence is added up. At the end of feeding experiment, growth performance and immune indexes to pig are analyzed.
2, data statistic analysis
Testing data adopts SPSS17.0 statistical software to carry out statistical study, the results are shown in following table.
Table 1 growth performance index
| Project | Control group | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Daily ingestion amount/kg | 1.35��0.04 | 1.58��0.02 | 1.62��0.06 | 1.65��0.08 |
| Day weight gain/kg | 0.52��0.01 | 0.64��0.05 | 0.68��0.03 | 0.72��0.05 |
| Feed-weight ratio | 2.60��0.02 | 2.47��0.04 | 2.38��0.05 | 2.29��0.07 |
Daily ingestion amount (ADFI): the feeding capacity of accurate recording each hurdle test pig and clout amount, calculates every pig average daily ingestion amount weekly and full phase average daily ingestion amount;
Day weight gain (ADG): test pig starts weekly and terminates morning 7:30 and weighs on an empty stomach, calculates the average daily gain weekly of every pig and full phase average daily gain;
Feed-weight ratio: (F/G): calculate according to food consumption and weightening finish.
Table 2 immune indexes and sickness rate
| Project | Control group | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| IgA/(g/L) | 0.11��0.02 | 0.24��0.03 | 0.30��0.04 | 0.38��0.01 |
| IgG/(g/L) | 6.00��0.34 | 8.15��0.98 | 8.57��0.47 | 8.90��0.78 |
| IgM(g/L) | 1.02��0.22 | 1.40��0.19 | 1.45��0.17 | 1.49��0.16 |
| Diarrhea rate (%) | 10.50% | 3.50% | 3.3% | 2.5% |
Immune indexes measures: the 7:30 in morning the last day that trial period terminates, and each group is chosen two and measured IgA, IgG and IgM level.
Result is analyzed: as can be seen from Table 1, daily ingestion amount, day weight gain and the feedstuff-meat ratio that embodiment is 3 groups is all better than other each group, and these three growth performance indexs of control group are all not as each test group. As can be seen from Table 2, IgA, IgG and IgM level in embodiment 3 groups of serum all higher than other each group, diarrhea rate all lower than other each group, the immune indexes level of each test group and diarrhea rate relatively test group all make moderate progress.
Conclusion: test-results shows, the fodder additives that the present invention obtains, compared with basal feed, significantly improves growth performance and the immune level of pig, reduces the diarrhea rate of pig, and immunizing power effectively improves.
The raw material of this product is green safety material, and can significantly reduce the diarrhea rate of pig, strengthen immunizing power and the growth performance of pig, can add in pig feed as the substitute of microbiotic, produce the mixed feed that disease resisting effect is good, the promotion pig speed of growth is fast, there are good using value and wide market outlook.
Claims (4)
1. one kind is improved immunizing power and improves the pig's feed additive of intestinal health, every 100 parts are made up of following raw materials by weight portion: vervain 3-5 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 3-5 part, Rhizome of Grass leaf Sweelflag 3-4 part, Root of Racemose Inula 1-2 part, Howthorn Leaf 2-4 part, Herba Centellae 1-2 part, carrot pomace 1-2 part, Aloe polysaccharide 0.5-1 part, probiotics 1-2 part, vitamins C 0.1-0.3 part, vitamins B10.1-0.2 part, vitamins D30.1-0.2 part, ��-carotene 0.1-0.2 part, calcium lactate 0.5-0.8 part, ferrous citrate 0.2-0.5 part, rose vitriol 0.1-0.2 part, all the other are carrier, carrier by defatted rice bran and wheat bran in mass ratio 2:1 form, defatted rice bran and wheat bran are pre-mixed pulverized 60 orders sieves.
2. a kind of according to claim 1 improve immunizing power and improve the pig's feed additive of intestinal health, every 100 parts are made up of following raw materials by weight portion: vervain 4 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 4 parts, Rhizome of Grass leaf Sweelflag 3.5 parts, Root of Racemose Inula 1.5 parts, Howthorn Leaf 3 parts, Herba Centellae 1.5 parts, carrot pomace 1.5 parts, Aloe polysaccharide 0.8 part, probiotics 1.5 parts, vitamins C 0.2 part, vitamins B10.15 part, vitamins D30.15 part, ��-carotene 0.15 part, calcium lactate 0.6 part, ferrous citrate 0.4 part, rose vitriol 0.15 part, all the other are carrier, carrier by defatted rice bran and wheat bran in mass ratio 2:1 form, defatted rice bran and wheat bran are pre-mixed pulverized 60 orders sieves.
3. a kind of pig's feed additive improving immunizing power and improve intestinal health according to claim 1 or 2, the addition in pig feed is 100-300g/t.
4. a kind of according to claim 3 improving immunizing power and improve the pig's feed additive of intestinal health, the addition in pig feed is 200g/t.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106538861A (en) * | 2016-10-12 | 2017-03-29 | 浙江海洋大学 | One boar immunomodulator and preparation method thereof, application |
| CN107183389A (en) * | 2017-06-28 | 2017-09-22 | 漳州傲农牧业科技有限公司 | A kind of feed addictive for reducing cholesterol absorption and its application |
| CN107307202A (en) * | 2017-06-01 | 2017-11-03 | 杭州科帝生物科技有限公司 | A kind of feed addictive preparation technology for cultivating pig enteron aisle health-care effect |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104146182A (en) * | 2014-08-28 | 2014-11-19 | 成都双胞胎饲料有限公司 | Biological feed additive for preventing and treating diarrhoea of piggies |
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2015
- 2015-12-30 CN CN201511011476.6A patent/CN105614102A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104146182A (en) * | 2014-08-28 | 2014-11-19 | 成都双胞胎饲料有限公司 | Biological feed additive for preventing and treating diarrhoea of piggies |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106538861A (en) * | 2016-10-12 | 2017-03-29 | 浙江海洋大学 | One boar immunomodulator and preparation method thereof, application |
| CN107307202A (en) * | 2017-06-01 | 2017-11-03 | 杭州科帝生物科技有限公司 | A kind of feed addictive preparation technology for cultivating pig enteron aisle health-care effect |
| CN107183389A (en) * | 2017-06-28 | 2017-09-22 | 漳州傲农牧业科技有限公司 | A kind of feed addictive for reducing cholesterol absorption and its application |
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Application publication date: 20160601 |