CN103415520B8 - 吡咯并六元杂芳环类衍生物、其制备方法及其在医药上的应用 - Google Patents

吡咯并六元杂芳环类衍生物、其制备方法及其在医药上的应用 Download PDF

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CN103415520B8
CN103415520B8 CN201280011688.2A CN201280011688A CN103415520B8 CN 103415520 B8 CN103415520 B8 CN 103415520B8 CN 201280011688 A CN201280011688 A CN 201280011688A CN 103415520 B8 CN103415520 B8 CN 103415520B8
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hetero
hexahydric
pyrrol
analog derivative
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CN103415520A (zh
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张学军
董庆
刘柏年
朱耀平
李晓涛
兰炯
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Jiangsu Hengrui Medicine Co Ltd
Shanghai Hengrui Pharmaceutical Co Ltd
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Shanghai Hengrui Pharmaceutical Co Ltd
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Abstract

本发明涉及吡咯并六元杂芳环类衍生物、其制备方法及其在医药上的应用。具体而言，本发明涉及一种通式(I)所示的新的吡啶并六元杂芳环类衍生物、其制备方法及含有该衍生物的药物组合物以及其作为治疗剂，特别是作为JAK抑制剂和免疫抑制剂的用途，其中通式(I)的各取代基与说明书中的定义相同。
CN201280011688.2A 2011-12-21 2012-12-19 吡咯并六元杂芳环类衍生物、其制备方法及其在医药上的应用 Active CN103415520B8 (zh)

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CN201280011688.2A CN103415520B8 (zh) 2011-12-21 2012-12-19 吡咯并六元杂芳环类衍生物、其制备方法及其在医药上的应用

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CN201110434071.9 2011-12-21
CN2011104340719 2011-12-21
CN201110434071 2011-12-21
PCT/CN2012/086922 WO2013091539A1 (zh) 2011-12-21 2012-12-19 吡咯并六元杂芳环类衍生物、其制备方法及其在医药上的应用
CN201280011688.2A CN103415520B8 (zh) 2011-12-21 2012-12-19 吡咯并六元杂芳环类衍生物、其制备方法及其在医药上的应用

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