CN103327984B - 包含在非水性溶剂中nsaid和抗生素的用于治疗乳腺炎的可注射组合物 - Google Patents

包含在非水性溶剂中nsaid和抗生素的用于治疗乳腺炎的可注射组合物 Download PDF

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Publication number
CN103327984B
CN103327984B CN201280005989.4A CN201280005989A CN103327984B CN 103327984 B CN103327984 B CN 103327984B CN 201280005989 A CN201280005989 A CN 201280005989A CN 103327984 B CN103327984 B CN 103327984B
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CN
China
Prior art keywords
compositions
antibiotic
inflammatory drug
nsaid
nonsteroidal anti
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CN201280005989.4A
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English (en)
Chinese (zh)
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CN103327984A (zh
Inventor
F·A·阿拉维
W·F·利奇
K·南加
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Bayer New Zealand Ltd
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Bayer New Zealand Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201280005989.4A 2011-01-20 2012-01-20 包含在非水性溶剂中nsaid和抗生素的用于治疗乳腺炎的可注射组合物 Active CN103327984B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ588686 2011-01-20
NZ588686A NZ588686A (en) 2011-01-20 2011-01-20 Injectable composition comprising an NSAID and an antibiotic in a non-aqueous solvent for treating a microbial infection in a mammary gland
PCT/NZ2012/000003 WO2012099479A1 (en) 2011-01-20 2012-01-20 Injectable compositions for mastitis comprising an nsaid and an antibiotic in a non-aqueous solvent

Publications (2)

Publication Number Publication Date
CN103327984A CN103327984A (zh) 2013-09-25
CN103327984B true CN103327984B (zh) 2016-08-17

Family

ID=46515931

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280005989.4A Active CN103327984B (zh) 2011-01-20 2012-01-20 包含在非水性溶剂中nsaid和抗生素的用于治疗乳腺炎的可注射组合物

Country Status (15)

Country Link
KR (1) KR101905173B1 (es)
CN (1) CN103327984B (es)
AU (1) AU2012207698A1 (es)
BR (1) BR112013018557B1 (es)
CL (1) CL2013002086A1 (es)
CO (1) CO6801732A2 (es)
CR (1) CR20130401A (es)
GT (1) GT201300182A (es)
IL (1) IL227540A (es)
MX (1) MX353876B (es)
NI (1) NI201300063A (es)
NZ (1) NZ588686A (es)
PE (1) PE20140035A1 (es)
WO (1) WO2012099479A1 (es)
ZA (1) ZA201305780B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2995297A1 (fr) * 2014-09-09 2016-03-16 Ceva Sante Animale Compositions parentérales et leurs utilisations
AR102172A1 (es) 2015-10-05 2017-02-08 Química Luar S R L Una composición farmacéutica bactericida y virucida
CN105663037A (zh) * 2016-01-27 2016-06-15 成都乾坤动物药业有限公司 一种阿莫西林溶液剂及其制备方法和用途
CN112472667B (zh) * 2019-08-23 2022-11-15 北京欧博方医药科技有限公司 一种维他昔布长效注射液及其制备方法和应用
CN111035614B (zh) * 2019-12-20 2024-02-02 北京喜禽药业有限公司 一种高含量土霉素注射液及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1600371A (zh) * 2003-09-22 2005-03-30 王玉万 以硅油为介质制备含抗微生物药物的制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787568B1 (en) * 2000-11-27 2004-09-07 Phoenix Scientific, Inc. Antibiotic/analgesic formulation and a method of making this formulation
EP1677781A4 (en) 2003-10-29 2008-11-19 Idexx Lab Inc SALTS OF PHARMACOLOGICALLY ACTIVE COMPOUNDS
DE102004025324A1 (de) * 2004-05-19 2005-12-08 Boehringer Ingelheim Vetmedica Gmbh Flüssige Zubereitung für die Veterinärmedizin, Verfahren zu deren Herstellung und deren Verwendung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1600371A (zh) * 2003-09-22 2005-03-30 王玉万 以硅油为介质制备含抗微生物药物的制剂

Also Published As

Publication number Publication date
MX2013008407A (es) 2013-09-26
AU2012207698A1 (en) 2013-04-18
ZA201305780B (en) 2014-04-30
CN103327984A (zh) 2013-09-25
NZ588686A (en) 2013-07-26
GT201300182A (es) 2014-07-28
KR101905173B1 (ko) 2018-11-28
BR112013018557A2 (pt) 2016-11-22
IL227540A (en) 2017-12-31
CL2013002086A1 (es) 2014-07-25
IL227540A0 (en) 2013-09-30
CR20130401A (es) 2014-02-04
CO6801732A2 (es) 2013-11-29
KR20140012646A (ko) 2014-02-03
WO2012099479A1 (en) 2012-07-26
NI201300063A (es) 2014-05-23
MX353876B (es) 2018-02-01
PE20140035A1 (es) 2014-02-16
BR112013018557B1 (pt) 2021-11-03

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