KR101905173B1 - 비-수성 용매 중 nsaid 및 항생제를 포함하는 유방염 치료를 위한 주사가능한 조성물 - Google Patents
비-수성 용매 중 nsaid 및 항생제를 포함하는 유방염 치료를 위한 주사가능한 조성물 Download PDFInfo
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- KR101905173B1 KR101905173B1 KR1020137021988A KR20137021988A KR101905173B1 KR 101905173 B1 KR101905173 B1 KR 101905173B1 KR 1020137021988 A KR1020137021988 A KR 1020137021988A KR 20137021988 A KR20137021988 A KR 20137021988A KR 101905173 B1 KR101905173 B1 KR 101905173B1
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- 125000000686 lactone group Chemical group 0.000 description 1
- 150000002634 lipophilic molecules Chemical class 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229920001684 low density polyethylene Polymers 0.000 description 1
- 239000004702 low-density polyethylene Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 235000020638 mussel Nutrition 0.000 description 1
- 229960002009 naproxen Drugs 0.000 description 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 description 1
- 210000002445 nipple Anatomy 0.000 description 1
- 229960002351 oleandomycin Drugs 0.000 description 1
- 235000019367 oleandomycin Nutrition 0.000 description 1
- RZPAKFUAFGMUPI-KGIGTXTPSA-N oleandomycin Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](O)[C@@H](C)C(=O)[C@]2(OC2)C[C@H](C)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C RZPAKFUAFGMUPI-KGIGTXTPSA-N 0.000 description 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 1
- 229960000625 oxytetracycline Drugs 0.000 description 1
- 235000019366 oxytetracycline Nutrition 0.000 description 1
- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- WSHJJCPTKWSMRR-RXMQYKEDSA-N penam Chemical compound S1CCN2C(=O)C[C@H]21 WSHJJCPTKWSMRR-RXMQYKEDSA-N 0.000 description 1
- 150000002960 penicillins Chemical class 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000004540 pour-on Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 210000003705 ribosome Anatomy 0.000 description 1
- 229960000371 rofecoxib Drugs 0.000 description 1
- RZJQGNCSTQAWON-UHFFFAOYSA-N rofecoxib Chemical compound C1=CC(S(=O)(=O)C)=CC=C1C1=C(C=2C=CC=CC=2)C(=O)OC1 RZJQGNCSTQAWON-UHFFFAOYSA-N 0.000 description 1
- VYGBQXDNOUHIBZ-UHFFFAOYSA-L sodium formaldehyde sulphoxylate Chemical group [Na+].[Na+].O=C.[O-]S[O-] VYGBQXDNOUHIBZ-UHFFFAOYSA-L 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 229960001294 spiramycin Drugs 0.000 description 1
- 235000019372 spiramycin Nutrition 0.000 description 1
- 229930191512 spiramycin Natural products 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000009044 synergistic interaction Effects 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 238000012385 systemic delivery Methods 0.000 description 1
- 229960003250 telithromycin Drugs 0.000 description 1
- LJVAJPDWBABPEJ-PNUFFHFMSA-N telithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)[C@@H](C)C(=O)O[C@@H]([C@]2(OC(=O)N(CCCCN3C=C(N=C3)C=3C=NC=CC=3)[C@@H]2[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)OC)C)CC)[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O LJVAJPDWBABPEJ-PNUFFHFMSA-N 0.000 description 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ588686 | 2011-01-20 | ||
NZ588686A NZ588686A (en) | 2011-01-20 | 2011-01-20 | Injectable composition comprising an NSAID and an antibiotic in a non-aqueous solvent for treating a microbial infection in a mammary gland |
PCT/NZ2012/000003 WO2012099479A1 (en) | 2011-01-20 | 2012-01-20 | Injectable compositions for mastitis comprising an nsaid and an antibiotic in a non-aqueous solvent |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20140012646A KR20140012646A (ko) | 2014-02-03 |
KR101905173B1 true KR101905173B1 (ko) | 2018-11-28 |
Family
ID=46515931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020137021988A KR101905173B1 (ko) | 2011-01-20 | 2012-01-20 | 비-수성 용매 중 nsaid 및 항생제를 포함하는 유방염 치료를 위한 주사가능한 조성물 |
Country Status (15)
Country | Link |
---|---|
KR (1) | KR101905173B1 (es) |
CN (1) | CN103327984B (es) |
AU (1) | AU2012207698A1 (es) |
BR (1) | BR112013018557B1 (es) |
CL (1) | CL2013002086A1 (es) |
CO (1) | CO6801732A2 (es) |
CR (1) | CR20130401A (es) |
GT (1) | GT201300182A (es) |
IL (1) | IL227540A (es) |
MX (1) | MX353876B (es) |
NI (1) | NI201300063A (es) |
NZ (1) | NZ588686A (es) |
PE (1) | PE20140035A1 (es) |
WO (1) | WO2012099479A1 (es) |
ZA (1) | ZA201305780B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2995297A1 (fr) * | 2014-09-09 | 2016-03-16 | Ceva Sante Animale | Compositions parentérales et leurs utilisations |
AR102172A1 (es) * | 2015-10-05 | 2017-02-08 | Química Luar S R L | Una composición farmacéutica bactericida y virucida |
CN105663037A (zh) * | 2016-01-27 | 2016-06-15 | 成都乾坤动物药业有限公司 | 一种阿莫西林溶液剂及其制备方法和用途 |
CN112472667B (zh) * | 2019-08-23 | 2022-11-15 | 北京欧博方医药科技有限公司 | 一种维他昔布长效注射液及其制备方法和应用 |
CN111035614B (zh) * | 2019-12-20 | 2024-02-02 | 北京喜禽药业有限公司 | 一种高含量土霉素注射液及其制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002041899A1 (en) | 2000-11-27 | 2002-05-30 | Phoenix Scientific, Inc. | An antibiotic/analgesic formulation and a method of making this formulation |
US20050148519A1 (en) | 2003-10-29 | 2005-07-07 | Murthy Yerramilli V.S. | Salts of pharmacologically active compounds |
US20050277634A1 (en) | 2004-05-19 | 2005-12-15 | Boehringer Ingelheim Vetmedica Gmbh | Liquid composition for veterinary medicine and process for the preparation and use thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1297319C (zh) * | 2003-09-22 | 2007-01-31 | 王玉万 | 以硅油为介质制备含抗微生物药物的制剂 |
-
2011
- 2011-01-20 NZ NZ588686A patent/NZ588686A/xx unknown
-
2012
- 2012-01-20 WO PCT/NZ2012/000003 patent/WO2012099479A1/en active Application Filing
- 2012-01-20 MX MX2013008407A patent/MX353876B/es active IP Right Grant
- 2012-01-20 KR KR1020137021988A patent/KR101905173B1/ko active IP Right Grant
- 2012-01-20 PE PE2013001576A patent/PE20140035A1/es not_active Application Discontinuation
- 2012-01-20 AU AU2012207698A patent/AU2012207698A1/en not_active Abandoned
- 2012-01-20 CN CN201280005989.4A patent/CN103327984B/zh active Active
- 2012-01-20 BR BR112013018557-0A patent/BR112013018557B1/pt active IP Right Grant
-
2013
- 2013-07-17 NI NI201300063A patent/NI201300063A/es unknown
- 2013-07-17 GT GT201300182A patent/GT201300182A/es unknown
- 2013-07-18 IL IL227540A patent/IL227540A/en not_active IP Right Cessation
- 2013-07-19 CL CL2013002086A patent/CL2013002086A1/es unknown
- 2013-07-31 ZA ZA2013/05780A patent/ZA201305780B/en unknown
- 2013-08-05 CO CO13186092A patent/CO6801732A2/es unknown
- 2013-08-19 CR CR20130401A patent/CR20130401A/es unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002041899A1 (en) | 2000-11-27 | 2002-05-30 | Phoenix Scientific, Inc. | An antibiotic/analgesic formulation and a method of making this formulation |
US20050148519A1 (en) | 2003-10-29 | 2005-07-07 | Murthy Yerramilli V.S. | Salts of pharmacologically active compounds |
US20050277634A1 (en) | 2004-05-19 | 2005-12-15 | Boehringer Ingelheim Vetmedica Gmbh | Liquid composition for veterinary medicine and process for the preparation and use thereof |
Also Published As
Publication number | Publication date |
---|---|
WO2012099479A1 (en) | 2012-07-26 |
BR112013018557B1 (pt) | 2021-11-03 |
MX2013008407A (es) | 2013-09-26 |
KR20140012646A (ko) | 2014-02-03 |
CN103327984B (zh) | 2016-08-17 |
NZ588686A (en) | 2013-07-26 |
NI201300063A (es) | 2014-05-23 |
AU2012207698A1 (en) | 2013-04-18 |
ZA201305780B (en) | 2014-04-30 |
IL227540A0 (en) | 2013-09-30 |
BR112013018557A2 (pt) | 2016-11-22 |
CR20130401A (es) | 2014-02-04 |
CL2013002086A1 (es) | 2014-07-25 |
IL227540A (en) | 2017-12-31 |
CO6801732A2 (es) | 2013-11-29 |
GT201300182A (es) | 2014-07-28 |
MX353876B (es) | 2018-02-01 |
PE20140035A1 (es) | 2014-02-16 |
CN103327984A (zh) | 2013-09-25 |
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