CN103180316A - 调节细胞内钙的化合物 - Google Patents

调节细胞内钙的化合物 Download PDF

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Publication number
CN103180316A
CN103180316A CN201180050485XA CN201180050485A CN103180316A CN 103180316 A CN103180316 A CN 103180316A CN 201180050485X A CN201180050485X A CN 201180050485XA CN 201180050485 A CN201180050485 A CN 201180050485A CN 103180316 A CN103180316 A CN 103180316A
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Prior art keywords
calcium
compound
aryl
pharmaceutically acceptable
alkyl
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CN201180050485XA
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English (en)
Chinese (zh)
Inventor
J·P·惠滕
Y·裴
J·曹
Z·王
E·罗杰斯
B·戴克
J·格里
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Calcimedica Inc
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Calcimedica Inc
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Priority to CN201710242277.9A priority Critical patent/CN106905311A/zh
Priority to CN202210177867.9A priority patent/CN114591311A/zh
Publication of CN103180316A publication Critical patent/CN103180316A/zh
Pending legal-status Critical Current

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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
CN201180050485XA 2010-08-27 2011-08-26 调节细胞内钙的化合物 Pending CN103180316A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201710242277.9A CN106905311A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物
CN202210177867.9A CN114591311A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37784210P 2010-08-27 2010-08-27
US61/377,842 2010-08-27
PCT/US2011/049424 WO2012027710A2 (en) 2010-08-27 2011-08-26 Compounds that modulate intracellular calcium

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201710242277.9A Division CN106905311A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物
CN202210177867.9A Division CN114591311A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物

Publications (1)

Publication Number Publication Date
CN103180316A true CN103180316A (zh) 2013-06-26

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CN201180050485XA Pending CN103180316A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物
CN202210177867.9A Pending CN114591311A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物
CN201710242277.9A Pending CN106905311A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物

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CN202210177867.9A Pending CN114591311A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物
CN201710242277.9A Pending CN106905311A (zh) 2010-08-27 2011-08-26 调节细胞内钙的化合物

Country Status (8)

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US (2) US9079891B2 (enExample)
EP (1) EP2609095A4 (enExample)
JP (1) JP5916149B2 (enExample)
CN (3) CN103180316A (enExample)
AU (1) AU2011293201B2 (enExample)
CA (1) CA2809830C (enExample)
MX (1) MX337711B (enExample)
WO (1) WO2012027710A2 (enExample)

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US10703722B2 (en) 2010-04-27 2020-07-07 Calcimedica, Inc. Compounds that modulate intracellular calcium
US9079891B2 (en) 2010-08-27 2015-07-14 Calcimedica, Inc. Compounds that modulate intracellular calcium
HRP20170499T1 (hr) 2011-05-23 2017-06-02 Merck Patent Gmbh Derivati tiazola
LT2820013T (lt) 2012-03-02 2018-10-25 Ralexar Therapeutics, Inc. Kepenų x receptoriaus (lxr) moduliatoriai, skirti odos ligų, sutrikimų ir būklių gydymui
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
EP2914587A1 (de) 2012-10-31 2015-09-09 Bayer CropScience AG Neue heterocylische verbindungen als schädlingsbekämpfungsmittel
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
EP3041834A4 (en) 2013-09-04 2017-01-18 Ralexar Therapeutics, Inc. Liver x receptor (lxr) modulators
BR112016004904B1 (pt) 2013-09-04 2023-01-24 Ellora Therapeutics, Inc. Compostos moduladores de receptor x do fígado (lxr), seu uso e composição farmaceutica compreendendo os mesmos
CA2978007A1 (en) 2015-02-27 2016-09-01 Calcimedica, Inc. Pancreatitis treatment
DK3331525T3 (da) * 2015-08-07 2020-12-14 Calcimedica Inc Anvendelse af CRAC-kanal-inhibitorer til behandling af slagtilfælde og traumatisk hjerneskade
WO2017178174A1 (en) * 2016-04-11 2017-10-19 Genfit Methods of treatment of cholestasis and fibrosis
ES2928408T3 (es) 2016-04-11 2022-11-17 Genfit Métodos para el tratamiento de enfermedades fibróticas
JP7193071B2 (ja) * 2017-02-08 2022-12-20 国立大学法人東海国立大学機構 蛍光発光材料および紫外線吸収剤
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