AU2011293201B2 - Compounds that modulate intracellular calcium - Google Patents

Compounds that modulate intracellular calcium Download PDF

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Publication number
AU2011293201B2
AU2011293201B2 AU2011293201A AU2011293201A AU2011293201B2 AU 2011293201 B2 AU2011293201 B2 AU 2011293201B2 AU 2011293201 A AU2011293201 A AU 2011293201A AU 2011293201 A AU2011293201 A AU 2011293201A AU 2011293201 B2 AU2011293201 B2 AU 2011293201B2
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Australia
Prior art keywords
optionally substituted
calcium
compound
pharmaceutically acceptable
aryl
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AU2011293201A1 (en
Inventor
Jianguo Cao
Brian Dyck
Jonathan Grey
Yazhong Pei
Evan Rogers
Zhijun Wang
Jeffrey P. Whitten
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Calcimedica Inc
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Calcimedica Inc
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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
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AU2011293201A 2010-08-27 2011-08-26 Compounds that modulate intracellular calcium Ceased AU2011293201B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37784210P 2010-08-27 2010-08-27
US61/377,842 2010-08-27
PCT/US2011/049424 WO2012027710A2 (en) 2010-08-27 2011-08-26 Compounds that modulate intracellular calcium

Publications (2)

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AU2011293201A1 AU2011293201A1 (en) 2013-04-04
AU2011293201B2 true AU2011293201B2 (en) 2015-11-05

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US (2) US9079891B2 (enExample)
EP (1) EP2609095A4 (enExample)
JP (1) JP5916149B2 (enExample)
CN (3) CN103180316A (enExample)
AU (1) AU2011293201B2 (enExample)
CA (1) CA2809830C (enExample)
MX (1) MX337711B (enExample)
WO (1) WO2012027710A2 (enExample)

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CN103180316A (zh) 2010-08-27 2013-06-26 钙医学公司 调节细胞内钙的化合物
CA2831966C (en) 2011-05-23 2016-07-19 Merck Patent Gmbh Thiazole derivatives
EP3441390A1 (en) * 2012-03-02 2019-02-13 Ralexar Therapeutics, Inc. Liver x receptor (lxr) modulators for the treatment of dermal diseases, disorders and conditions
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
CN104884449A (zh) 2012-10-31 2015-09-02 拜尔农作物科学股份公司 作为害虫防治剂的新的杂环化合物
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
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SG11201601644RA (en) 2013-09-04 2016-04-28 Alexar Therapeutics Inc Liver x receptor (lxr) modulators
AU2014315280B2 (en) 2013-09-04 2019-01-24 Ellora Therapeutics, Inc. Liver X receptor (LXR) modulators
CN114712513B (zh) * 2015-02-27 2026-02-10 钙医学公司 胰腺炎治疗
AU2016306301B2 (en) * 2015-08-07 2021-02-11 Calcimedica, Inc. Use of CRAC channel inhibitors for the treatment of stroke and traumatic brain injury
PT3442580T (pt) 2016-04-11 2020-12-23 Genfit Métodos de tratamento para doenças colestáticas e fibróticas
JP2019513762A (ja) * 2016-04-11 2019-05-30 ジェンフィＧｅｎｆｉｔ 胆汁うっ滞及び線維症の処置方法
JP7193071B2 (ja) * 2017-02-08 2022-12-20 国立大学法人東海国立大学機構 蛍光発光材料および紫外線吸収剤
CN108299418A (zh) * 2017-09-14 2018-07-20 刘双伟 一种抗过敏和哮喘的噻唑基烟酰胺类化合物的合成方法
US10670609B2 (en) 2017-09-22 2020-06-02 Government Of The United States, As Represented By The Secretary Of The Air Force Ytterbium as a surrogate cation to measure calcium flux
CN113557020A (zh) 2018-09-14 2021-10-26 瑞真药业公司 包含crac抑制剂和皮质类固醇的组合物及其使用方法
US12544371B2 (en) 2020-03-20 2026-02-10 Calcimedica, Inc. Methods and compositions for treating acute lung injury and acute respiratory distress syndrome
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