AU2011293201B2 - Compounds that modulate intracellular calcium - Google Patents

Compounds that modulate intracellular calcium Download PDF

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Publication number
AU2011293201B2
AU2011293201B2 AU2011293201A AU2011293201A AU2011293201B2 AU 2011293201 B2 AU2011293201 B2 AU 2011293201B2 AU 2011293201 A AU2011293201 A AU 2011293201A AU 2011293201 A AU2011293201 A AU 2011293201A AU 2011293201 B2 AU2011293201 B2 AU 2011293201B2
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optionally substituted
calcium
compound
pharmaceutically acceptable
aryl
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AU2011293201A1 (en
Inventor
Jianguo Cao
Brian Dyck
Jonathan Grey
Yazhong Pei
Evan Rogers
Zhijun Wang
Jeffrey P. Whitten
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Calcimedica Inc
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Calcimedica Inc
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    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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AU2011293201A 2010-08-27 2011-08-26 Compounds that modulate intracellular calcium Active AU2011293201B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37784210P 2010-08-27 2010-08-27
US61/377,842 2010-08-27
PCT/US2011/049424 WO2012027710A2 (en) 2010-08-27 2011-08-26 Compounds that modulate intracellular calcium

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AU2011293201A1 AU2011293201A1 (en) 2013-04-04
AU2011293201B2 true AU2011293201B2 (en) 2015-11-05

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US (2) US9079891B2 (enExample)
EP (1) EP2609095A4 (enExample)
JP (1) JP5916149B2 (enExample)
CN (3) CN103180316A (enExample)
AU (1) AU2011293201B2 (enExample)
CA (1) CA2809830C (enExample)
MX (1) MX337711B (enExample)
WO (1) WO2012027710A2 (enExample)

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US10703722B2 (en) 2010-04-27 2020-07-07 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2012027710A2 (en) 2010-08-27 2012-03-01 Calcimedica Inc. Compounds that modulate intracellular calcium
CN103596938B (zh) 2011-05-23 2016-12-28 默克专利有限公司 噻唑衍生物
HUE040231T2 (hu) * 2012-03-02 2019-02-28 Ralexar Therapeutics Inc Máj X receptor (LXR) modulátorok bõrbetegségek, rendellenességek és állapotok kezelésére
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
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EP2738172A1 (en) * 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
US9981913B2 (en) 2013-09-04 2018-05-29 Ralexar Therapeutics, Inc. Liver X receptor (LXR) modulators
CN110003108A (zh) 2013-09-04 2019-07-12 瑞雷克萨治疗公司 肝脏x受体(lxr)调节剂
EP3261641B1 (en) 2015-02-27 2023-07-12 Calcimedica, Inc. Pancreatitis treatment
CA2995094A1 (en) * 2015-08-07 2017-02-16 Calcimedica, Inc. Use of crac channel inhibitors for the treatment of stroke and traumatic brain injury
JP2019513762A (ja) * 2016-04-11 2019-05-30 ジェンフィGenfit 胆汁うっ滞及び線維症の処置方法
SG11201808402RA (en) 2016-04-11 2018-10-30 Genfit Methods of treatment for cholestatic and fibrotic diseases
JP7193071B2 (ja) * 2017-02-08 2022-12-20 国立大学法人東海国立大学機構 蛍光発光材料および紫外線吸収剤
CN108299418A (zh) * 2017-09-14 2018-07-20 刘双伟 一种抗过敏和哮喘的噻唑基烟酰胺类化合物的合成方法
US10670609B2 (en) 2017-09-22 2020-06-02 Government Of The United States, As Represented By The Secretary Of The Air Force Ytterbium as a surrogate cation to measure calcium flux
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