AU2011293201B2 - Compounds that modulate intracellular calcium - Google Patents

Compounds that modulate intracellular calcium Download PDF

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Publication number
AU2011293201B2
AU2011293201B2 AU2011293201A AU2011293201A AU2011293201B2 AU 2011293201 B2 AU2011293201 B2 AU 2011293201B2 AU 2011293201 A AU2011293201 A AU 2011293201A AU 2011293201 A AU2011293201 A AU 2011293201A AU 2011293201 B2 AU2011293201 B2 AU 2011293201B2
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optionally substituted
calcium
compound
pharmaceutically acceptable
aryl
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AU2011293201A1 (en
Inventor
Jianguo Cao
Brian Dyck
Jonathan Grey
Yazhong Pei
Evan Rogers
Zhijun Wang
Jeffrey P. Whitten
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Calcimedica Inc
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Calcimedica Inc
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    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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AU2011293201A 2010-08-27 2011-08-26 Compounds that modulate intracellular calcium Active AU2011293201B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37784210P 2010-08-27 2010-08-27
US61/377,842 2010-08-27
PCT/US2011/049424 WO2012027710A2 (en) 2010-08-27 2011-08-26 Compounds that modulate intracellular calcium

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AU2011293201A1 AU2011293201A1 (en) 2013-04-04
AU2011293201B2 true AU2011293201B2 (en) 2015-11-05

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US (2) US9079891B2 (enExample)
EP (1) EP2609095A4 (enExample)
JP (1) JP5916149B2 (enExample)
CN (3) CN103180316A (enExample)
AU (1) AU2011293201B2 (enExample)
CA (1) CA2809830C (enExample)
MX (1) MX337711B (enExample)
WO (1) WO2012027710A2 (enExample)

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PL2820013T3 (pl) 2012-03-02 2019-01-31 Ralexar Therapeutics, Inc. Modulatory receptorów X wątroby (LXR) do leczenia chorób, zaburzeń i stanów skórnych
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
JP2016503395A (ja) 2012-10-31 2016-02-04 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 病害生物防除剤としての複素環化合物
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
MX2016002930A (es) 2013-09-04 2016-12-02 Ralexar Therapeutics Inc Moduladores del receptor x hepatico (lxr).
SI3041835T1 (sl) 2013-09-04 2020-09-30 Ellora Therapeutics, Inc. Modulatorji jetrnih X receptorjev (LXR)
EP3778595B1 (en) 2015-02-27 2021-08-25 Calcimedica, Inc. Pancreatitis treatment
EP3331525B1 (en) * 2015-08-07 2020-10-07 Calcimedica, Inc. Use of crac channel inhibitors for the treatment of stroke and traumatic brain injury
US20170290814A1 (en) * 2016-04-11 2017-10-12 Genfit Methods of treatment of cholestasis and fibrosis
AU2017249602B2 (en) 2016-04-11 2022-06-16 Genfit Methods of treatment for cholestatic and fibrotic diseases
JP7193071B2 (ja) * 2017-02-08 2022-12-20 国立大学法人東海国立大学機構 蛍光発光材料および紫外線吸収剤
CN107501258B8 (zh) * 2017-09-14 2018-10-16 青岛大学附属医院 一种噻唑基烟酰胺类化合物及其在制备抗过敏和哮喘药物中的应用
US10670609B2 (en) 2017-09-22 2020-06-02 Government Of The United States, As Represented By The Secretary Of The Air Force Ytterbium as a surrogate cation to measure calcium flux
MX2021003094A (es) 2018-09-14 2021-05-12 Rhizen Pharmaceuticals A G Composiciones que comprenden un inhibidor de crac y un corticosteroide y métodos de uso de estas.
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