CN103172589A - 噻唑基-二氢-喹唑啉 - Google Patents
噻唑基-二氢-喹唑啉 Download PDFInfo
- Publication number
- CN103172589A CN103172589A CN201310049412XA CN201310049412A CN103172589A CN 103172589 A CN103172589 A CN 103172589A CN 201310049412X A CN201310049412X A CN 201310049412XA CN 201310049412 A CN201310049412 A CN 201310049412A CN 103172589 A CN103172589 A CN 103172589A
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- CN
- China
- Prior art keywords
- alkyl
- quinazoline
- group
- methyl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 26
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- 125000003161 (C1-C6) alkylene group Chemical group 0.000 claims 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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| US20070259855A1 (en) * | 2006-04-06 | 2007-11-08 | Udo Maier | Thiazolyl-dihydro-indazole |
| US7691868B2 (en) | 2006-04-06 | 2010-04-06 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-quinazoline |
| JPWO2010024258A1 (ja) * | 2008-08-29 | 2012-01-26 | 塩野義製薬株式会社 | Ｐｉ３ｋ阻害活性を有する縮環アゾール誘導体 |
| TW201103943A (en) * | 2009-04-27 | 2011-02-01 | Shionogi & Co | Urea derivative having pi3k inhibitory activity |
| EA201200087A1 (ru) * | 2009-07-02 | 2012-07-30 | Новартис Аг | 2-карбоксамиды циклоаминомочевин, которые являются ингибиторами pi3k |
| US11633399B2 (en) | 2018-12-25 | 2023-04-25 | Sol-Gel Technologies Ltd. | Treatment of skin disorders with compositions comprising an EGFR inhibitor |
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| EP0032879A1 (de) * | 1980-01-21 | 1981-07-29 | Ciba-Geigy Ag | Neue Benzthiazolyl-harnstoffderivate, deren Herstellung, sie enthaltende Mittel und deren Verwendung als Herbizide |
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| SK12712002A3 (sk) | 2000-02-07 | 2003-02-04 | Abbott Gmbh & Co. Kg | Deriváty 2-benzotiazolylmočoviny a ich použitie ako inhibítorov proteínkináz |
| US20040009613A1 (en) * | 2001-02-16 | 2004-01-15 | Ming-Ming Zhou | Methods of identifying modulators of bromodomains |
| US6608053B2 (en) | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| TWI314928B (en) | 2002-02-28 | 2009-09-21 | Novartis A | 5-phenylthiazole derivatives and use as pi3 kinase inhibitors |
| MXPA05000453A (es) | 2002-07-10 | 2005-03-23 | Applied Research Systems | Derivados de benceno fusionados a azolidinona-vinilo. |
| PT2042504E (pt) | 2002-09-30 | 2011-09-07 | Bayer Schering Pharma Ag | Derivados da azolepirimidina fundida |
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| CN1897950A (zh) | 2003-10-14 | 2007-01-17 | 惠氏公司 | 稠合芳基和杂芳基衍生物及其使用方法 |
| UY29149A1 (es) | 2004-10-07 | 2006-05-31 | Boehringer Ingelheim Int | Tiazolil-dihidro-indazoles |
| US20060106013A1 (en) | 2004-10-07 | 2006-05-18 | Boehringer Ingelheim International Gmbh | PI3-kinases |
| US7691868B2 (en) | 2006-04-06 | 2010-04-06 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-quinazoline |
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| US20070238718A1 (en) | 2006-04-06 | 2007-10-11 | Matthias Grauert | Thiazolyl-dihydro-indazole |
| US20070238746A1 (en) * | 2006-04-06 | 2007-10-11 | Trixi Brandl | Thiazolyl-dihydro-chinazoline |
| US7517995B2 (en) | 2006-04-06 | 2009-04-14 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-cyclopentapyrazole |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0032879A1 (de) * | 1980-01-21 | 1981-07-29 | Ciba-Geigy Ag | Neue Benzthiazolyl-harnstoffderivate, deren Herstellung, sie enthaltende Mittel und deren Verwendung als Herbizide |
Non-Patent Citations (2)
| Title |
|---|
| 无: "Methods for identifying modulators of bromodomain activity and for treating HIV infections", 《CHEMICAL ABSTRACTS TM WEB EDITION》 * |
| 无: "Synthesis and antimicrobial activity of new tetrahydrobenzothiazole derivatives", 《CHEMICAL ABSTRACTS TM WEB EDITION》 * |
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| DK2018385T3 (da) | 2013-08-26 |
| US20100145041A1 (en) | 2010-06-10 |
| JP5303450B2 (ja) | 2013-10-02 |
| MX2008011957A (es) | 2008-10-01 |
| ES2425051T3 (es) | 2013-10-11 |
| RU2008143546A (ru) | 2010-06-27 |
| US20070244104A1 (en) | 2007-10-18 |
| EP2018385B1 (de) | 2013-05-15 |
| BRPI0710575A2 (pt) | 2012-06-19 |
| JP2009532413A (ja) | 2009-09-10 |
| AU2007236043A1 (en) | 2007-10-18 |
| US8334378B2 (en) | 2012-12-18 |
| WO2007115929A1 (de) | 2007-10-18 |
| US7691868B2 (en) | 2010-04-06 |
| EP2018385A1 (de) | 2009-01-28 |
| TW200804402A (en) | 2008-01-16 |
| IL194490A0 (en) | 2009-08-03 |
| CN101460505B (zh) | 2013-03-20 |
| CN101460505A (zh) | 2009-06-17 |
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