TW200804402A - Thiazolyl-dihydro-quinazoline - Google Patents
Thiazolyl-dihydro-quinazoline Download PDFInfo
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- TW200804402A TW200804402A TW096111946A TW96111946A TW200804402A TW 200804402 A TW200804402 A TW 200804402A TW 096111946 A TW096111946 A TW 096111946A TW 96111946 A TW96111946 A TW 96111946A TW 200804402 A TW200804402 A TW 200804402A
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- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
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- 125000001412 tetrahydropyranyl group Chemical group 0.000 description 1
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- HTJXMOGUGMSZOG-UHFFFAOYSA-N tiaramide Chemical compound C1CN(CCO)CCN1C(=O)CN1C(=O)SC2=CC=C(Cl)C=C21 HTJXMOGUGMSZOG-UHFFFAOYSA-N 0.000 description 1
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- 229950003899 tofimilast Drugs 0.000 description 1
- LBLYYCQCTBFVLH-UHFFFAOYSA-M toluenesulfonate group Chemical class C=1(C(=CC=CC1)S(=O)(=O)[O-])C LBLYYCQCTBFVLH-UHFFFAOYSA-M 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
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- 229940100640 transdermal system Drugs 0.000 description 1
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- 150000003852 triazoles Chemical class 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/14—Decongestants or antiallergics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Pulmonology (AREA)
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- Neurology (AREA)
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- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| EP06112300 | 2006-04-06 |
Publications (1)
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| TW200804402A true TW200804402A (en) | 2008-01-16 |
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| CN (2) | CN101460505B (enExample) |
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| MX (1) | MX2008011957A (enExample) |
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| WO (1) | WO2007115929A1 (enExample) |
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| US20070259855A1 (en) * | 2006-04-06 | 2007-11-08 | Udo Maier | Thiazolyl-dihydro-indazole |
| US20070238746A1 (en) * | 2006-04-06 | 2007-10-11 | Trixi Brandl | Thiazolyl-dihydro-chinazoline |
| US7691868B2 (en) | 2006-04-06 | 2010-04-06 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-quinazoline |
| US20110230472A1 (en) * | 2008-08-29 | 2011-09-22 | Shionogi & Co., Ltd. | Ring-fused azole derivative having pi3k-inhibiting activity |
| WO2010125799A1 (ja) * | 2009-04-27 | 2010-11-04 | 塩野義製薬株式会社 | Pi3k阻害活性を有するウレア誘導体 |
| EA201200087A1 (ru) * | 2009-07-02 | 2012-07-30 | Новартис Аг | 2-карбоксамиды циклоаминомочевин, которые являются ингибиторами pi3k |
| JP2022515256A (ja) | 2018-12-25 | 2022-02-17 | ソル － ゲル テクノロジーズ リミテッド | Ｅｇｆｒ阻害剤を含む組成物による皮膚障害の治療 |
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| US238730A (en) * | 1881-03-08 | Wagon-brake | ||
| US244104A (en) * | 1881-07-12 | andrews | ||
| US238718A (en) * | 1881-03-08 | Efeico eosenzi | ||
| US259855A (en) * | 1882-06-20 | Fbank s | ||
| US4380640A (en) * | 1980-01-21 | 1983-04-19 | Ciba-Geigy Corporation | Novel benzthiazolylurea derivatives, compositions containing them and their use as herbicides |
| PL357099A1 (en) * | 2000-02-07 | 2004-07-12 | Abbott Gmbh & Co.Kg | 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors |
| US20040009613A1 (en) * | 2001-02-16 | 2004-01-15 | Ming-Ming Zhou | Methods of identifying modulators of bromodomains |
| US6608053B2 (en) | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| AR038703A1 (es) | 2002-02-28 | 2005-01-26 | Novartis Ag | Derivados de 5-feniltiazol y uso como inhibidor de quinasa p i 3 |
| MXPA05000453A (es) | 2002-07-10 | 2005-03-23 | Applied Research Systems | Derivados de benceno fusionados a azolidinona-vinilo. |
| WO2004029055A1 (en) | 2002-09-30 | 2004-04-08 | Bayer Pharmaceuticals Corporation | Fused azole-pyrimidine derivatives |
| BR0316386A (pt) | 2002-12-06 | 2005-09-27 | Warner Lambert Co | Benzoxazin-3-onas e seus derivados como inibidores de p13k |
| WO2004056820A1 (en) | 2002-12-20 | 2004-07-08 | Warner-Lambert Company Llc | Benzoxazines and derivatives thereof as inhibitors of pi3ks |
| CA2528938A1 (en) | 2003-06-13 | 2005-02-24 | Zentaris Gmbh | Compounds having inhibitive activity of phosphatidylinositol 3-kinase and methods of use thereof |
| GB0315966D0 (en) | 2003-07-08 | 2003-08-13 | Cyclacel Ltd | Compounds |
| CN1897950A (zh) | 2003-10-14 | 2007-01-17 | 惠氏公司 | 稠合芳基和杂芳基衍生物及其使用方法 |
| UY29149A1 (es) | 2004-10-07 | 2006-05-31 | Boehringer Ingelheim Int | Tiazolil-dihidro-indazoles |
| US7691888B2 (en) | 2004-10-07 | 2010-04-06 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-indazole |
| US20070238718A1 (en) | 2006-04-06 | 2007-10-11 | Matthias Grauert | Thiazolyl-dihydro-indazole |
| US7517995B2 (en) | 2006-04-06 | 2009-04-14 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-cyclopentapyrazole |
| US7691868B2 (en) | 2006-04-06 | 2010-04-06 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-quinazoline |
| US20070238746A1 (en) * | 2006-04-06 | 2007-10-11 | Trixi Brandl | Thiazolyl-dihydro-chinazoline |
| US20070259855A1 (en) | 2006-04-06 | 2007-11-08 | Udo Maier | Thiazolyl-dihydro-indazole |
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| AU2007236043B2 (en) | 2012-09-13 |
| JP5303450B2 (ja) | 2013-10-02 |
| BRPI0710575A2 (pt) | 2012-06-19 |
| AR060269A1 (es) | 2008-06-04 |
| MX2008011957A (es) | 2008-10-01 |
| WO2007115929A8 (de) | 2008-06-19 |
| KR20090029181A (ko) | 2009-03-20 |
| CA2647056A1 (en) | 2007-10-18 |
| ZA200807349B (en) | 2009-07-29 |
| CN101460505B (zh) | 2013-03-20 |
| US20100145041A1 (en) | 2010-06-10 |
| EP2018385A1 (de) | 2009-01-28 |
| IL194490A0 (en) | 2009-08-03 |
| US20070244104A1 (en) | 2007-10-18 |
| AU2007236043A1 (en) | 2007-10-18 |
| US8334378B2 (en) | 2012-12-18 |
| WO2007115929A1 (de) | 2007-10-18 |
| DK2018385T3 (da) | 2013-08-26 |
| RU2008143546A (ru) | 2010-06-27 |
| US7691868B2 (en) | 2010-04-06 |
| EP2018385B1 (de) | 2013-05-15 |
| JP2009532413A (ja) | 2009-09-10 |
| ES2425051T3 (es) | 2013-10-11 |
| NZ572508A (en) | 2011-11-25 |
| CN101460505A (zh) | 2009-06-17 |
| CN103172589A (zh) | 2013-06-26 |
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