CN103083535A - Dark tea composition and application in weight losing field - Google Patents

Dark tea composition and application in weight losing field Download PDF

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CN103083535A
CN103083535A CN2012105701422A CN201210570142A CN103083535A CN 103083535 A CN103083535 A CN 103083535A CN 2012105701422 A CN2012105701422 A CN 2012105701422A CN 201210570142 A CN201210570142 A CN 201210570142A CN 103083535 A CN103083535 A CN 103083535A
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tea
fat
sharp
rhizoma
rhizoma alismatis
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贺志弘
黄泽波
艾立平
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Abstract

The invention discloses a dark tea composition and an application in the weight losing field. The dark tea composition is prepared into tea products, capsules, tablets, granules and the like through Anhua black tea (Fuzhuan tea, Hua-zhuan tea, Qing-zhuan tea and Hei-zhuan tea; Huajuan dark tea such as Qianliang tea and Bailiang tea; Tianjian dark tea, Shengjian dark tea, Gongjian dark tea and the like) containing a Fuzhuan dark tea factor A and a Fuzhuan dark tea factor B as active components, gynostemma pentaphylla, rhizoma alismatis, radix ophiopogonis and other medicinal and dietary materials, and have quite remarkable and durable weight losing and lipid reducing functions on various obese people without rebound.

Description

A kind of postfermented tea compositions, and in the application in field of losing weight
Technical field
A kind of postfermented tea compositions, and in the application in field of losing weight, belong to the category of biomedicine field.Particularly, relate to a kind of postfermented tea compositions, and in the application in field of losing weight, adopt the ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, the black brick tea that contain FUCHA prime factor A, FUCHA prime factor B active component; Hua-juan tea such as thousand tael tea, hundred liang of tea; It point, to give birth to point, tribute sharp etc.), the integration of edible and medicinal herbs class article such as Herb Gynostemmae Pentaphylli, Rhizoma Alismatis, Radix Ophiopogonis make tea product, capsule, tablet or granule etc., all kinds of obese peoples are had fairly obvious, persistency fat-reducing and antihyperglycemic, and do not rebound.
Background technology
As everyone knows, in the world, fat (Obesity) is that body fat quantity increases or the volume hypertrophy causes the body weight pathological state of body weight more than 20% that be above standard.In recent years, no matter be developed country or developing country, the obesity sickness rate all is the trend of rising, has become the primary health problem in the whole world.The report of World Health Organization (WHO) points out, the whole world approximately has 2.5 hundred million adult to suffer from obesity at present, and at least 5 hundred million Genus Homos are in super severe one in addition.And in population of adolescent, fat trend is more obvious, has become a major challenge of Global Health cause.According to incompletely statistics, global obesity and the surprising speed increment of doubling in every 5 years, annual because the direct or indirect death toll that obesity promotes has reached 300,000 people.The fat consequence that spreads health, economy and the social mentality aspect brought is very serious.Obesity is not only a kind of single disease, and it can also be by the effect of organism metabolism, causes the abnormal of whole body a plurality of systems, becomes the arch-criminal of various diseases.It has increased the probability of happening of type ii diabetes, hypertension, dyslipidemias, cardiovascular and cerebrovascular disease, cholelithiasis and some tumor, osteoarthritis, polycystic ovary syndrome.The overweight people compares with non-overweight people, and its sickness rate significantly increases, and to the dangerous maximum of diabetes, cardiovascular and cerebrovascular disease, is especially also to cause its main causes of death.
Obesity is a kind of complexity, overdetermined Metabolic disorder disease, is all possible cause fat factor as hormone, environment, life style and the diet of gene, adjusting energy balance.Essentially, obesity comes from the destroyed of balance between food intake and energy expenditure.
The medicine for the treatment of of obesity at present mainly contains chemical drugs, plant amedica two class appetrol.The treatment mechanism of chemicals can be divided into 3 classes: central appetite suppressant (norepinephrine agonist, serotonin agonist, norepinephrine-serotonin agonist etc.); Short energy expenditure medicine (norepinephrine agonist, β 3-adrenoceptor agonists etc.); Suppress to digest and assimilate medicine (as lipase inhibitor etc.).The effect of the medicine appetite-suppressing maincenters such as central appetite suppressant such as amfetamine, hydrogen Xi Ting, Sertraline, sibutramine is stronger, treatment of obesity has effect preferably, but the significantly side effect such as insomnia, cardiopalmus, headache, gastrointestinal upset, hypertension and nervousness is arranged.And long-term taking can cause the generation of drug dependence and cardiovascular disease, diabetes.Suppress to digest and assimilate medicine orlistat (orlistat) and can cause that gastrointestinal peristalsis is abnormal.Short energy expenditure medicine such as gemfibrozil, beclobrate, Lovastatin etc. are the hypolipidemic of certain curative effect, but also with in various degree toxic and side effects.Plant amedica comprises plant extraction agent, Chinese herbal medicine class and Chinese medicinal formulae class, all have in various degree blood fat reducing and the effect of fat-reducing, but also with in various degree toxic and side effects.In sum, the chemical drugs for the treatment of of obesity and Chinese herbal medicine have certain side effect and untoward reaction mostly.The slimming medicines take Sibutramine hydrochloride (Sibutramine HCL) as main component such as Sibutramine Hydrochloride capsule that occupy a large amount of domestic markets share of called optical imaging have been stopped sale in recent years, thereby have occurred the situation of fat-reducing medicine imbalance of supply and demand on market.
Summary of the invention
Scientific theory is thought, the reason that obesity produces has multiple, wherein, a kind of known result of study of modern medicine circle proves, AMPK (protein kinase, AMP-activated protein kinase) is heterotrimer (Heterotrimer) albumen that is made of α, β, γ subunit (Subunit), exists more in the myotube cell, also being present in brain, heart, fatty tissue and liver, is a kind of enzyme.AMPK is the important sensor of perception intracellular energy level.It is regulated appetite stimulator, body weight adjusting, blood glucose regulation and blood lipid metabolism and plays the role of a nucleus.
When high-intensity exercise or long-time starvation, for a large amount of consumption of adenosine triphosphate (ATP), adenylic acid (AMP) concentration rises, and therefore, AMP is combined with the γ of AMPK subunit, thereby causes the activation of AMPK.Substantial activation is showed by the phosphorylation to AMPK alpha subunit threonine (Threonine) (Thr)-172 residues by the upper phosphorylase that is called LKBI or CaMKK.
The AMPK of phosphorylation form press down to suppress consumes the synthetic of biochemical reaction-fatty acid of ATP and cholesterol, and in contrast, it makes the fatty acid beta-oxidation that generates ATP, and (process of β-oxidation) and glycolytic cycle (glycolysis) are activated.Moreover, also increase amount as the GLUT4 (glucosetransporter4, GLUT4) of cell membrane glucose absorption path.In addition, the activation of AMPK and the P13K signal under insulin action pass on mechanism irrelevant, make the cell membrane of intracellular glucose absorption path GLUT4 move increase.In addition, when AMPK is activated under phosphorylation, as insulin synthesis core enzyme HMG-CoA reductase (Hydroxymethylglutaryl-CoA-reductase, hyd roxymethylglutaryl-CoA reductase) the generation phosphorylation of another the next albumen.HMG-CoA reductase inactivation (inactivation) as a result, the synthetic reduction of cholesterol, thus make the cholesterol in blood reduce.
The AMPK enzyme that becomes the activation form by phosphorylation makes as the synthetic core enzyme ACC (acetyl-CoA carboxylase of its next albumen fatty acid, acetyl-CoA carboxylase) serine (ser)-79 residue generation phosphorylation suppresses the activity of this ACC enzyme.Its result, the activation of AMPK reduce the generation of core metabolite-malonyl in the fatty acid synthetic reaction-CoA (Malonyl-CoA), suppress the synthetic of fatty acid.The AMPK activation causes when malonaldehyde-CoA reduces, and to the inner fatty acid-long acyl-CoA (Long chain acyl-CoA) that flows into of mitochondrion (mitochondria), promotes beta-oxidation.Under the condition that high concentration malonyl-CoA exists; long acyl is sent to mitochondrial CPT1 (carnitine palmityl-CoA-transferase; carnitine palmitoy-CoA transferase) be suppressed; make the concentration reduction of malonyl-CoA due to the activation of AMPK; elimination along with this obstructive action; make the fatty acid stream of long acyl-CoA form enter mitochondrion inside, increase beta-oxidation, so the neutral lipid in body fat and blood reduces.
Under study for action, researcher is found, the activation of AMPK causes PGC-1 α (Pexoxisome proliferator-peroxisome proliferator-activated receptor gamma coactivator-1 α, Peroxisome proliferator-activated receptor gamma co activator-1 α) phosphorylation, activate in addition histone deacetylase (Histone deacet ylase) a kind of-SIRT1 (silent message regulation and control T1, Silent Information Regul atory T1).Its result, the phosphorylation of the PGC-1 α that occurs under AMPK and SIRT1 effect and go acidylate, make Metabolism of Mitochondria active, can obtain diabetes and obesity improves effect (Canto and Auwerx, lipidemia newly sees periodical 20,98-105,2009 (Canto and Au werx, Curr.Opin.Lipidol.20,98-105,2009)); Canto etc., nature ((Natur e) 458,1056~1060,2009) therefore, the activation of AMPK can suppress the synthetic of body fat acid and cholesterol, and promotes the beta-oxidation of body fat and promote the effects such as Cell uptake of blood-glucose.Therefore, the material of activation AMPK can be used for improving or treating obesity, diabetes and hyperlipidemia crowd's health effectively.
The whole world medical circle be fully recognized that, Chinese medicine has very huge development prospect and power of influence in every field such as fat-reducing.This is because theory of Chinese medical science is machine-processed with clinical treatment with many target spots, multipath, whole machine balancing.It more than Western Modern medical science have safer, better the treatment and health-care effect.Simultaneously, in China, in numerous plant medicines, as the active substance in Chinese herbal medicine, have than above-mentioned research and increase more significantly protein kinase (AMP-activated protein kinase) activity (AMPK), can improve insulin resistance, improve the metabolic disease that comprises obesity and hyperlipidemia etc.Activity to AMPK exerts an influence, and the phosphorylation ability of its AMPK and enzyme activation ability have obtained the effects anb Mechanism of further enhancing, and its therapeutic effect is better than Western medicine far away, and has no side effect.As: correlational study is verified, a kind of plant amedica Herb Gynostemmae Pentaphylli and its extract that are grown in China can significantly increase protein kinase (AMP-activated protein kinase) activity (AMPK), can improve insulin resistance, improve the metabolic disease that comprises obesity and hyperlipidemia etc.Activity to AMPK exerts an influence, and phosphorylation ability and the enzyme activation ability of its AMPK have obtained further enhancing.Its treatment diabetes, obesity, the effect that reduces body fat, blood neutral fat and cholesterol is significantly improved.
The present invention take theory of Chinese medical science and clinical in foundation, has done further, a large amount of scientific researches just in this respect.
Chinese medicine just has discussion to the understanding of " obesity " in " Ling Shu Miraculous Pivot or Divine Axis is contrary along plump ", that say is namely the people of obesity to its " wide shoulder, wide axil, wide item, greasiness, pachydermia " of putting down in writing." the logical deficiency and excess opinion of commenting of Plain Questions " pointed out: " fertile high official, the disease of fat meat and fine grain also." " the Plain Questions writings left behind by the deceased " think " spleen deficiency of kidney-QI, the defeated cloth mistake of transporting department pure and impure mixed mutually, do not change essence and blood, hold in cream fat expectorant is turbid, and it are fat to cause fat "." danxi's experiential therapy " cloud: " fertile white man's excessive phlegm ", " mostly fertile people is phlegm retention "." the secret record in stone chamber " day: " fertile people's excessive phlegm, be the deficiency of vital energy also, void gas can not transporting, therefore the expectorant life." therefore, obesity belongs to motherland's medical science " phlegm-damp " " turbid resistance ", " blood stasis " category.Factor body weakness of the spleen and stomach, or " excessive rest on bed impairing QI ", the polyphagia rich and fatty diet, with the passing of time must damage taste in addition, insufficiency of the spleen transformation failure of spleen, cause the turbid interior life of expectorant, turbid damp gathers, and holds in cream fat, send out as fat, or damp-phlegm with the passing of time, the retardance mechanism of qi, qi depression to blood stasis, blood fortune is unsmooth, and lipid transforms not normal, and the people is got fat.In a word, fat formation is lost fortune as this take deficiency of spleen-QI and stomach-QI, and the retardance of phlegm-damp turbid pathogen is mark.
The etiology of Huangdi's Internal Classics is under the organic conception of " correspondence between man and universe " instructs, with yin-yang and five elements, hide resemble, the theory such as meridians is as theoretical basis.It thinks that the ill main cause of human body is many-sided, has that being invaded by exogenous pathogen, disorder of emotion, intemperance of taking food, daily life are not normal, labor (labour, work with one's mind, exhaustion due to sexual indulgence) degree of escaping, injury from falling down etc.Drinking and eating irregularly wherein, the polyphagia delicious food is to cause one of ill major reason of human body." the strange sick opinion of Plain Questions " cloud: " husband's five tastes entrance is hidden in stomach, and spleen is its vital essence of trip, and body fluid is at spleen, therefore make us sweet taste in the mouth also; This fertile institute is sent out also; This person must count the sweet and refreshing and many fertilizer of food also, the overeating greasy food bringing about internal heat, and the over-eating the food with sweet flavor bringing about abdominal distension is therefore its gas overflow transfers to and quenching one's thirst.”
" Plain Questions vital QI of the body connecting with natural QI opinion " day: " change of Sorghum vulgare Pers., foot is given birth to nail-like boil, is subjected to as holding void." " the strange sick opinion of Plain Questions " cloud: " eat sweet and refreshing and many fertilizer also." " Plain Questions passages through which vital energy circulates another matter " day: " food gas enters stomach, conveyance of turbid essence to the heart, transporting essential substances to vessel." " Plain Questions logical comment deficiency and excess opinion " cloud: " all diseases due to endogenous heat of ZANG FU organs, sudden falling down, hemiplegia, flaccidity with cold limbs ", " fullness caused by stagnant QI is sent out contrary, sweet fertile high official fat meat and fine grain disease also.”
" Plain Questions vital QI of the body connecting with natural QI opinion " cloud: " thereby be satiated with food, flaccidity of muscles and vessels, intestinal are hemorrhoid." " Plain Questions numbness opinion " cloud: " eating twice as usual, the intestines and stomach are wound." this shows that the polyphagia delicious food is also given birth to expectorant and given birth to wet, strongly fragrant and fire-transformation can cause diabetes, hypertension, obesity, hyperlipidemia, cerebral thrombosis, furuncle carbuncle and intestinal tract disease etc. for a long time.
Obesity also association has hypertension, hyperlipidemia, all diseases of hyperglycemia, and this point had a large amount of discussions already in Chinese medicine.As:
1, the diet of diabetes causes a disease and sees
Diabetes are traditional Chinese medical science indication diabetes." interior warp " proposes: innate deficiency, the five internal organs weakness, direct stimulation, disorder of emotion, surfeit delicious food, obesity, all can quench one's thirst---diabetes.The main pathogenesis of quenching one's thirst is that natural endowment is not enough, the five internal organs are weak, the cloudy life of the refining day after tomorrow is not enough, causes asthenia of both the spleen and kidney; Eating and drinking without temperance, surfeit delicious food, obesity, pure wine savoury, impairing the spleen and stomach in addition, transporting and transforming function of the spleen and stomach mistake department; Long-term excessive direct stimulation, feelings will are not relaxed, the lung stomach-Yin of burning on depressed rage impairing the liver, the liver failing to maintain the normal flow of QI, stagnated QI transforming into fire Tianjin, lower bright kidney liquid, excessive thinking, motive pent-up, stagnated QI transforming into fire, hyperactivity of heart-fire, the sad spleen essence and blood of consumption, the stomach kidney yin of also burning liquid; Again because invading, take up internal organs, consumption of body fluid by heat in diseases caused by exogenous pathogenic factor six climate exopathogens, dryness-fire wind heat poison heresy; Or take for a long time red medicine, dryness-transformation impairment of body fluid, the consume of cloudy Tianjin; Accumulate in impairing the spleen and stomach, the accumulated heat of drinking for a long time, fire-transformation impairment of body fluid, intemperate sexual intercourse, impairment caused by overstrain excessively, kidney essense loss, deficiency-fire produced in the interior, the cloudy Tianjin of burning all can cause the generation of diabetes.The common change disease of diabetes has skin sore and furuncle carbuncle, cataract and retinopathy, lung abscess, pulmonary tuberculosis, nephropathy and peripheral neuropathy, hypertension, coronary heart disease, arteriosclerosis, cerebral thrombosis etc.Furuncle carbuncle is to stop up in the skin space between skin and muscles due to scorching, and battalion is cloudy is burnt and form that expectorant is turbid, venation block, accumulate poison and become pus, therefore be furuncle carbuncle; Lung being a delicate viscus, the scorching lung gold of burning is stopped up stagnant lung network, and the lung mistake is moistened foster, with the passing of time concurrent lung abscess or pulmonary tuberculosis; Scorching impairment of YIN, liver blood secretly consumption, damage of kidney-YIN, liver lose moisten foster, Liver and kidney essence and blood can not on hold in order, easily complicated cataract and retinopathy; Deficiency of YIN affecting YANG, spleen kidney yang weakness of QI loses, and the defeated cloth of body fluid is limited, and water retention overflows in gastrointestinal and skin, forms edema, dropsy (diabetic nephropathy); Spleen governing muscles, for extremity this, liver governing tendons, kidney governing bones, the later stage deficiency of YIN affecting YANG of quenching one's thirst, deficiency in both YIN and YANG, the dirty equal void of liver,spleen,kidney three declines, positive QI-insufficiency in addition, phlegm-damp hold that blood stasis, retardance meridians, QI-blood circulation are smooth, muscles and bones muscle loses in moistening to support and forms numbness, arthromyodynia, flaccidity (diabetic peripheral neuropathy) under the arm; Scorching bright Tianjin, the body fluid deficiency QI consumed, the deficiency of vital energy is difficult transporting compress essence of water and grain, be detained in sering, with the passing of time form expectorant turbid, hinder QI-blood circulation, make it the stasis of blood stagnant and form blood stasis, expectorant is turbid, blood stasis hinders in the blood vessels meridians, hoodwinks thinking and forms the diseases such as the thoracic obstruction, apoplexy, hemiplegia (coronary heart disease, arteriosclerosis, cerebral thrombosis).
2, the diet of hypertension causes a disease and sees
Hypertension belongs to Chinese medicine " dizzy ", " headache " category.Dizzy see the earliest " interior warp " is referred to as " dizziness ".Dizzyly refer to dim eyesight, dizzyly refer to dizziness, be referred to as dizzy.The lighter closes order and has a rest and can stop, and severe one is as among ship by bus, and it is indefinite to rotate, and can not stand, or with nauseating, vomiting, sweating, very faint.Some patient has headache concurrently, and what have has a dull ache, the swollen twinge of some weights, and the pain gesture that also has is more acute, pain with distension upper punch, jumping pain very, nausea and vomiting, stiffness of the nape limb fiber crops.Do not have a dizzy spell, the have a headache performance of feeling of fullness in the head of minority patients with hypertension is also arranged.
" danxi's experiential therapy dizziness " is partially main has the opinion of " dizziness must be caused by phlegm " in expectorant, proposes the method for " controlling expectorant for first ", and surfeit delicious food savoury, the impairment of the spleen hinders stomach, strong fortune mistake department, so that indigestion is precise and tiny, accumulatively wet raise phlegm, stagnation of phlegm-damp in middle-JIAO, clear YANG failing to ascend, turbid YIN failing to descend causes dizzy.The cause of disease multiterminal of headache, headkerchief are " confluence of all yang-channels ", " mansion of clear sun ", be again the brain place, the blood of all the five internal organs elite, the gas of the clear sun of six internal organs, annotate in head all, attack therefore the heresy of six climate exopathogens is outer, top, upper criminal mountain peak, pathogen is delaied, and prevents sun clearly, or all diseases of internal injury, cause QI and blood disorderly contrary, the stasis blocking meridians, brain is become homeless foster, all can have a headache.As eating and drinking without temperance, the delicious food of being addicted to drink, dysfunction of the spleen in transportation is given birth in phlegm-damp, and upper illiteracy empties, and checks clearly sun and causes headache.
Modern medicine study shows, the sodium Excessive Intake can cause hypertension, " interior warp " to early be recognized." the Ling Shu Miraculous Pivot or Divine Axis five tastes " day: " salty flavor acting on blood, making us of polyphagia is thirsty." " interior warp " cloud: " and distinguish the flavor of too salty, DAGU, gas labor, and brevis, depression of heart-QI.”
3, the diet of obesity causes a disease and sees
Obesity is due to partially containing as main pathogenesis take deficiency of vital energy phlegm-damp that many reasons causes, causes the interior cream fat overheap of body, and body weight is above standard body weight more than 20%, and how weak with dizziness, spiritlessness and sparing of words, a class disease of the symptom such as take offence less short.Record the earliest to primary disease sees " interior warp ", as having in " interior warp ", descriptions such as " dysfunction of vision and hearing are bright for Nian Wushi, body weight " is arranged in " fertile high official ", " Plain Questions ".Primary disease belongs to the time of deficiency in origin and excess in superficiality more, and deficiency in origin mostly is spleen, deficiency of kidney-QI take the deficiency of vital energy as main, the QI-deficiency of the heart and lung of holding concurrently; Mark is real to stop in phlegm-damp cream fat, or double water is wet, blood stasis, the stagnation of QI etc., and clinical often have a relatively difference of deficiency in origin and mark reality.Forefathers have saying of " fertile people's excessive phlegm ", " how wet fertile people is ", " the many deficiency of vital energys of fertile people ", are namely for its different pathogenesis.Light-duty fat patient has no adverse reaction more, and following symptom can appear in medium-sized and heavy fat patient: two lower limb have sense of heaviness, tachypnea when movable, and physical work is easily tired, the anteflexion difficulty of bending over, waist, skelalgia, hyperhidrosis that To Be Protected from Heat, skin wrinkle is rotten to the corn; Drowsiness sleeping soundly, the polyphagia polyphagia, happiness food snacks, the confection sweet food is namely felt cardiopalmus, cold sweat, hands as untimely feed and is quivered; Infrequent menstruation, even amenorrhea is sterile.The food of excessive delicious food, biochemical is fertile people or fat people for cream fat is piled up in body.Surfeit delicious food savoury, but also impairing the spleen and stomach, transporting and transforming function of the spleen and stomach mistake department causes retention of damp-heat in the interior, or stays in skin, makes body fat.The traditional Chinese medical science is thought " excessive rest on bed impairing QI ", " the motionless essence of shape does not flow, and essence does not flow the stagnation of QI ", and quiet and motionless, QI and blood is popular not smooth, the taste mechanism of qi is dull, transportation capabilities imbalance, the defeated cloth obstacle of essence of water and grain, turn to cream fat and expectorant turbid, stagnant in tissue, skin, internal organs, meridians, and it is fat to cause fat.Fat pathological changes with the passing of time, he is sick for Chang Biansheng.Have realized that in " interior warp " that the diseases such as fat and diseases due to endogenous heat of ZANG FU organs are relevant, overweight people extremely, the diseases such as normal easily merging is quenched one's thirst, headache, dizzy, the thoracic obstruction, apoplexy, gallbladder-distention, arthromyodynia.
4, the diet of hyperlipemia causes a disease and sees
Hyperlipemia is the modern medicine name of disease, though the special topic of motherland's medical science ahyperlipoidemia is discussed, mentions that in " interior warp " " adipose membrane ", " precise and tiny ", " cream people " reach titles such as " fat people "." Plain Questions passages through which vital energy circulates another matter " cloud: " food gas enters stomach, conveyance of turbid essence to the heart, transporting essential substances to vessel ".Hyperlipidemia is pathological product, is again paathogenic factor, meets the pathology category of motherland's medical science " expectorant ".Its etiology and pathogenesis can be summarized as: the polyphagia delicious food, and disorder of the spleen and stomach caused by internal damage, dysfunction of the spleen in transportation, the qi-blood-body fluid obstacle, " clearly from turbidization, fat is given birth to by expectorant ", drink stops, turbidly stay that fat is poly-.
Nowadays, along with growth in the living standard, people live and work in peace and contentment, and do not worry about food and clothing, and more and more pay attention to the health of health, pay attention to seeking the ways to keep in good health such as life prolonging." Plain Questions ancient times innocent opinion " cloud: " daily life often has for behaving according to the law of YIN YANG, and in physicopsychic training techniques, proper diet, avoiding overstrain, thus can somatic and spiritual harmony, and to the greatest extent whole its natural life-span, spend and at the age of one hundred years oldly be." " Plain Questions vital QI of the body connecting with natural QI opinion " cloud: " and born of yin, this is at the five tastes; Five ZANG-organs where store the vital essence, being damaged by five flavors.Hereat too acid of flavor, irritability is with Tianjin, exhaustion of spleen-QI; Distinguish the flavor of too salty, injury of skeleton, and brevis, depression of heart-QI; Flavor is too bitter, obstruction of heart-QI with dyspnea, darkish complexion, imbalance of kidney-QI; Distinguish the flavor of too sweet, retardation of spleen-QI due to dryness, gastric qi is thick; Flavor is too hot, atrophy and flaccidity of tendons and vessels, and spirit is the centre, carefully coordinating five kinds of flavor in foodstuff hereat, solid skeleton and pliable tendons, QI-blood circulating regularly, one's pores will be fine in texture, sound skeleton and pure essence QI in this way, careful road such as method, long have a longevity." therefore reasonable diet is avoided delicious food pure wine savoury, the food of the fibre rich such as polyphagia vegetable, fruit, vitamin suitably replenishes protein, suitable low sugar, low fat, less salt; Form good dietary habit, avoid polyphagia, eating and drinking too much at one meal, the diet snacks are only the road of correct diet, even, still can bring into play its positive role in health field, thereby benefit the whole mankind in quite flourishing modern society in science and technology.
In sum, the pathogenesis that links closely adopts the method for the treating both the principal and secondary aspects of a disease of replenishing QI to invigorate the spleen the lucid yang sending up, dehumidifying resolving phlegm lowering turbidity, can reach the purpose of fat-reducing.
The formula of this product is under the Chinese medicine traditional theory instructs, and belongs to deficiency-weakness of spleen-QI for obesity, clear YANG failing to ascend, and stagnation of phlegm-damp, the crowd who holds in turbid fat, select the product of function replenishing QI to invigorate the spleen the lucid yang sending up, dehumidifying resolving phlegm lowering turbidity: Herb Gynostemmae Pentaphylli sweet in the mouth, hardship in formula, cold in nature.Return spleen, lung meridian." Chinese medicine voluminous dictionary " says its " eliminating inflammation and expelling toxin, eliminating phlegm and stopping cough are controlled chronic tracheitis "." clinical Chinese medicine dictionary " carries its energy " preventing phlegm from forming and stopping coughing, spleen invigorating is regulated the flow of vital energy, benefiting QI for activating blood circulation, promoting the production of body fluid to quench thirst, detoxification and promoting urination "; Can bring into play replenishing QI to invigorate the spleen, the turbid effect of dispelling of reducing phlegm.Semen Cassiae is sweet, bitter, return Liver Channel, large intestine channel, effect with liver heat removing and eyesight improving, suppressing the hyperactive liver and subsiding YANG, intestine moistening intestinal stasis relieving, disappeared stagnant dividing from stool, be adjuvant drug in the side, it mainly contains the anthraquinone component that dissociates or be combined into glycosides, and zoopery and clinical practice prove that all it can reduce serum low-density LP, suppress the formation of serum cholesterol rising and Aorta atheromatous plague, Semen Cassiae water extraction liquid and alcohol extract have blood pressure lowering and diuresis to laboratory animal.The Folium Nelumbinis bitter in the mouth, property is flat.Return liver, spleen, stomach warp.Has clearing away summer-heat, sending up the lucid YANG, the function of cooling blood for hemostasis." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries its " wind heat of upper refresh oneself, only dizzy, clearing away phlegm loses heart, preventing or arresting vomiting, a vexed pain "; The Compendium of Material Medica cloud its: " hair growth promoting vigour, benefit helps taste, arresting seminal emission is turbid, dissipating blood stasis blood, clear water is swollen, carbuncle sore, sends out varioliform exanthema." sending up the lucid YANG is with strengthening the spleen and stomach, reducing phlegm, it is evil with the turbid descending to wet.L-carnitine has been considered the nutrient of needed by human, can regulate blood fat, defatting beauty.Zhu Pin coordinates, and brings out the best in each other, and plays altogether replenishing QI to invigorate the spleen, sending up the lucid YANG, Cleering damp and dissolving phlegm, the merit of the turbid blood fat reducing that disappears.
On this basis, in conjunction with the achievement in research of modern medicine, contain more than 80 kind of saponin as modern study proof Herb Gynostemmae Pentaphylli, wherein have 6 kinds similar to the ginsenoside, also contain saccharide, flavonoid, vitamin C, and 18 seed amino acids and multiple inorganic elements etc.Bibliographical information, Herb Gynostemmae Pentaphylli total glycosides are the main effective ingredient of Herb Gynostemmae Pentaphylli, have blood fat reducing, antioxidation, resist myocardial ischemia and the various biological function such as ischemical reperfusion injury, have been applied at present clinical as fat-reducing dietic medicinal.Also there are some researches show: Herb Gynostemmae Pentaphylli total glycosides tablet can obviously reduce the content (P<0.01) of hyperlipidemia rats cholesterol in serum, triglyceride and low density lipoprotein, LDL; Low the cutting with height of acute blood stasis model rat be can significantly reduce and whole blood contrast viscosity, plasma viscosity and platelet aggregation rate cut.Thereby the prompting Herb Gynostemmae Pentaphylli total glycosides tablet can reduce blood fat by blood circulation promoting and blood stasis dispelling.Semen Cassiae is sweet, bitter, return Liver Channel, large intestine channel, effect with liver heat removing and eyesight improving, suppressing the hyperactive liver and subsiding YANG, intestine moistening intestinal stasis relieving, disappeared stagnant dividing from stool, be adjuvant drug in the side, it mainly contains the anthraquinone component that dissociates or be combined into glycosides, and zoopery and clinical practice prove that all it can reduce serum low-density LP, suppress the formation of serum cholesterol rising and Aorta atheromatous plague, Semen Cassiae water extraction liquid and alcohol extract have blood pressure lowering and diuresis to laboratory animal.Folium Nelumbinis contains nuciferine, nuciferine, miltanthin, armepavine, pronuciferine (+)-Pronuciferine, N-demethyl nuciferine, D-N-methyl coclaurine, anonaine, liriodendrin, Quercetin, isoquercitin, lotus glycoside, tartaric acid, citric acid, malic acid, gluconic acid, oxalic acid, succinic acid, tannin etc.Experimentation has confirmed that the Folium Nelumbinis biology total alkali has obvious fat-reducing and effect for reducing fat, after medication, growth figure such as the Lee.s index of reflection body obese degree, body fat and blood fat have obvious decline, the obese rat body weight is subject to obvious inhibition, and in antiobesity action, animal activity is normal, without the obviously phenomenon generation of diarrhoea and appetite-suppressing, can think that the Folium Nelumbinis biology total alkali has antiobesity action preferably.Also studies show that, the Folium Nelumbinis water decoction can make the TC of hyperlipidemia rats 25.6%~39.3%, the TG that descends descend 18.9%~39.2%, and HDL-C is had no obvious impact, but with the reduction of TC, TG, LDL-C significantly descends; The Folium Nelumbinis water decoction can reduce whole blood contrast viscosity simultaneously, packed cell volume, thus improve the dense sticking state of blood, illustrate that the Folium Nelumbinis water decoction has obvious effect for reducing fat.
This provides a Gospel for vast obesity patient undoubtedly.Therefore, effort through the inventor, on aforesaid Research foundation, we have screened and have proved conclusively the ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, the black brick tea that contain FUCHA prime factor A, FUCHA prime factor B active component in the following technical scheme that provides; Hua-juan tea such as thousand tael tea, hundred liang of tea; It point, to give birth to point, tribute sharp etc.) and its extract, integration of edible and medicinal herbs class article Herb Gynostemmae Pentaphylli, Fructus Lycii, Rhizoma Alismatis, Radix Ophiopogonis, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Flos Caryophylli, Rhizoma Polygoni Cuspidati, Folium Nelumbinis, Rhizoma Alismatis, Semen Cuscutae, Fructus Ligustri Lucidi, Herba Ecliptae, Radix Polygoni Multiflori, Radix Et Rhizoma Rhei and its extract to treatment or improve the obesity crowd very good fat-reducing effect is arranged.Simultaneously, clinical trial certificate, a kind of postfermented tea compositions of the present invention, and the application process in the field of losing weight does not have toxic and side effects and the untoward reaction of appearance as sibutramine.
Therefore, technical scheme provided by the invention is:
A kind of postfermented tea compositions, and at the application process in field of losing weight, it has comprised by postfermented tea, particularly ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It point, to give birth to point, tribute sharp etc.) for key component, comprise what integration of edible and medicinal herbs class material Herb Gynostemmae Pentaphylli, Fructus Lycii, Rhizoma Alismatis, Radix Ophiopogonis, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Flos Caryophylli, Rhizoma Polygoni Cuspidati, Folium Nelumbinis, Rhizoma Alismatis etc. formed, also further can comprise the compositions of Semen Cuscutae, Fructus Ligustri Lucidi, Herba Ecliptae, Radix Polygoni Multiflori, Radix Et Rhizoma Rhei etc.
A kind of postfermented tea compositions, and at the application process in field of losing weight, its production technology such as following step:
1., take ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It point, to give birth to point, tribute sharp etc.), be ground into 30~90 purpose broken ends, standby.
2. or, take ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It is sharp, life is sharp, tribute is sharp etc.), drop in extraction pot, add the water of 6~16 times, extract under High Temperature High Pressure, get filtrate, filter, be evaporated to the extractum of relative density 1.05~1.40 (60 ℃ of intermittent fever are surveyed), filter, spray drying gets tea extract.Standby.
3., take above-mentioned integration of edible and medicinal herbs class article Herb Gynostemmae Pentaphylli, Fructus Lycii, Rhizoma Alismatis, Radix Ophiopogonis, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Flos Caryophylli, Rhizoma Polygoni Cuspidati, Folium Nelumbinis, Rhizoma Alismatis, Semen Cuscutae, Fructus Ligustri Lucidi, Herba Ecliptae, Radix Polygoni Multiflori, Radix Et Rhizoma Rhei equal portions, drop in extraction pot, the water that adds 6~16 times, extract under High Temperature High Pressure, get filtrate, filter concentrating under reduced pressure, vacuum≤-0.07Mpa~-0.08Mpa, temperature≤70 ℃; To the extractum of relative density 1.10~1.35 (60 ℃ intermittent fever survey), filter, spray drying, drying condition be decided to be vacuum≤, temperature≤70 ℃ are dried to moisture<3%.Get extract.Standby.
4., get 63~99% broken end of ANHUA HEI CHA and/or tea extracts of proper ratio, add 1~37% integration of edible and medicinal herbs class article and/or extract, mixing is made teabag and/or capsule finished product by the processing technology of teabag and/or capsule respectively.
According to obesity crowd's clinical manifestation, can select the multiple administering mode of having generally acknowledged.For example can adopt oral mode.Form as formula for a product of the present invention, comprise traditional carrier and additive such as adjuvant.Carrier of the present invention is so long as the carrier that gains public acceptance on the pharmacology comprises pH aqueous buffer solution, phosphoric acid or citric acid etc.The aminoacid such as water-soluble polymer-polyvinylpyrrolidone, glycine, glutamate, Glu, agedoite, arginine or lysine, and the carbohydrate such as glucose, mannose, glucosan also can be as carrier.The chelating agen such as EDTA, mannitol, sorbitol and non-polar surfactant's tween (TWEEN), PEG (Polyethylene Glycol, polyet hyleneglycol) also can be used as carrier and use.As the carrier that obtains on the pharmacology authenticating and diluent, comprise solution, dispersant, disintegrating agent and the penetrating agent of all kinds, and the absorption delay agent.The method of utilizing of the upper active substance related preparations of these pharmacologys is known, puts down in writing as existing document.Unless comprise all preparations outside the preparation that is not inconsistent with pharmaceutically active substance.Can also add other complementary element in said composition, as containing chromium, manganese, zinc, nicotinic acid, vitamin B6, vitamin B12 etc.Here, can also contain treating fat medicable HCA (hydroxycitric acid, hydroxycitric acid) and CLA (conjugated linoleic acid, conjugated linoleic acid) etc.
During oral administration, also can add the excipient of the nonhazardous effect that gets the nod on the pharmacology.Comprise mannitol, glucosan (Polydextrose), maltodextrin glucose (Malto dextrose), starch, lactose, magnesium stearate, glucide, Talcum (talc), cellulose, glucose, gelatin, white sugar, magnesium carbonate etc. as operable excipient.This based composition can be made into the forms such as solution, suspension, tablet (tablet), pill, capsule, powder, and can add the excipient of the nonhazardous effect that gets the nod on pharmacology.
In addition, when being made into tablet (tablet), pill, capsule, can also contain following adjuvant.As, the binding agents such as karaya (Tragacanth Gum) Flos Robiniae Pseudoacaciae, corn starch, gelatin, the excipient such as calcium phosphate, the distintegrants such as corn starch, potato starch and alginic acid (alginic), the lubricants such as magnesium stearate, the sweeting agents such as white sugar, lactose, the aromatic that extracts from Herba Menthae, Herba pyrolae japonicae (wintergreen), Fructus Pruni pseudocerasi etc., if unit capacity adopts capsule form, except the adjuvant of above-mentioned prompting, also can add liquid carrier.If adopt syrup or tincture form, together with effective ingredient, the sweeting agents such as white sugar be can contain and as another name for (methyl) and the propylparaben (Propyl paraben) of antiseptic, Fructus Pruni pseudocerasi and Fructus Citri junoris aromatic also can be added as coloring agent and aromatic.It is refining, nontoxic that all adjuvants that preparation is used during unit capacity should be, such as adding the diluent such as lactose, white sugar, calcium phosphate, the lubricants such as magnesium stearate, the binding agents such as starch, polyvinylpyrrolidone, Flos Robiniae Pseudoacaciae natural gum, gelatin, cellulose.
Beneficial effect
at described ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea, Hua-juan tea such as thousand tael tea, hundred liang of tea, it point, give birth to point, tribute point etc.) with integration of edible and medicinal herbs class article Herb Gynostemmae Pentaphylli, Fructus Lycii, Rhizoma Alismatis, Radix Ophiopogonis, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Flos Caryophylli, Rhizoma Polygoni Cuspidati, Folium Nelumbinis, Rhizoma Alismatis, Semen Cuscutae, Fructus Ligustri Lucidi, Herba Ecliptae, Radix Polygoni Multiflori, a kind of and/or multiple in Radix Et Rhizoma Rhei etc., as with integration of edible and medicinal herbs class article Herb Gynostemmae Pentaphylli, Fructus Lycii, Rhizoma Alismatis, Radix Ophiopogonis, Ganoderma, Fructus Crataegi, Flos Caryophylli, Rhizoma Polygoni Cuspidati, Folium Nelumbinis, Rhizoma Alismatis, during the compatibilities such as Radix Polygoni Multiflori, the active component that it contains such as FUCHA element A, FUCHA element B, and other active substance and when content is suitable, the phosphorylation ability of its AMPK is enhanced, the enzyme activation ability is significantly increased.And have the treatment of the synthetic inhibition ability of body fat, fatty acid beta-oxidation promotion ability, Biosynthesis of cholesterol inhibition ability, hyperlipidemia and improve the treatment of effect, obesity and improve effect.And, particularly importantly do not rely on insulin that the cell membrane locomotivity of grape cell HUCEP-8 GLUT4 is significantly improved, can effectively reduce the blood glucose of diabetics, and this point, with the ANHUA HEI CHA compatibility after effect particularly remarkable.
So the conclusion that can affirm is, a kind of postfermented tea compositions, and remarkable in the effect of the application in fat-reducing field, and do not produce toxic and side effects.
Specific embodiment
Embodiment 1
1., take ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It point, to give birth to point, tribute sharp etc.) 5000g, be ground into 30~90 purpose broken ends, standby.
2. or, take ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It is sharp, life is sharp, tribute is sharp etc.) 300kg, drop in extraction pot, add the water of 6~16 times, extract under High Temperature High Pressure, get filtrate, filter, be evaporated to the extractum of relative density 1.05~1.40 (60 ℃ of intermittent fever are surveyed), filter, spray drying gets tea extract.Standby.
3., take above-mentioned integration of edible and medicinal herbs class article Herb Gynostemmae Pentaphylli 25kg, Fructus Lycii 15kg, Rhizoma Alismatis 10kg, Radix Ophiopogonis 10kg, Ganoderma 12kg, Fructus Crataegi 8kg, Flos Chrysanthemi 8kg, Flos Caryophylli 6kg, Rhizoma Polygoni Cuspidati 6kg, Folium Nelumbinis 6kg, Rhizoma Alismatis 6kg, Semen Cuscutae 6kg, Fructus Ligustri Lucidi 12kg, Herba Ecliptae 12kg, Radix Polygoni Multiflori 12kg, Radix Et Rhizoma Rhei 10kg, drop in extraction pot, the water that adds 8~12 times, extract under High Temperature High Pressure, get filtrate, filter, concentrating under reduced pressure, vacuum≤-0.07Mpa~-0.08Mpa, temperature≤70 ℃; To the extractum of relative density 1.10~1.35 (60 ℃ intermittent fever survey), filter, spray drying, drying condition be decided to be vacuum≤, temperature≤70 ℃ are dried to moisture<3%.Get extract.Standby.
Preferably, above-mentioned Chinese medicine formula be Herb Gynostemmae Pentaphylli 25kg, Fructus Lycii 15kg, Rhizoma Alismatis 10kg, Radix Ophiopogonis 10kg, Ganoderma 12kg, Fructus Crataegi 8kg, Flos Chrysanthemi 8kg, Flos Caryophylli 6kg, Rhizoma Polygoni Cuspidati 6kg, Folium Nelumbinis 6kg, Rhizoma Alismatis 6kg.
4., to get weight portion be 85~95% broken end of ANHUA HEI CHA and/or tea extracts, adds 5~25% integration of edible and medicinal herbs class article and/or extract, mixing, dry, make teabag by the processing technology of known teabag.Cobalt 60Sterilization, check, packing, warehouse-in.
The preparation of embodiment 2 capsules
1., take ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It is sharp, life is sharp, tribute is sharp etc.) 300kg, drop in extraction pot, add the water of 6~16 times, extract under High Temperature High Pressure, get filtrate, filter, be evaporated to the extractum of relative density 1.05~1.40 (60 ℃ of intermittent fever are surveyed), filter, spray drying gets tea extract.Standby.
2., take above-mentioned integration of edible and medicinal herbs class article Herb Gynostemmae Pentaphylli 25kg, Fructus Lycii 15kg, Rhizoma Alismatis 10kg, Radix Ophiopogonis 10kg, Ganoderma 12kg, Fructus Crataegi 8kg, Flos Chrysanthemi 8kg, Flos Caryophylli 6kg, Rhizoma Polygoni Cuspidati 6kg, Folium Nelumbinis 6kg, Rhizoma Alismatis 6kg, Semen Cuscutae 6kg, Fructus Ligustri Lucidi 12kg, Herba Ecliptae 12kg, Radix Polygoni Multiflori 12kg, Radix Et Rhizoma Rhei 10kg, drop in extraction pot, the water that adds 8~12 times, extract under High Temperature High Pressure, get filtrate, filter, concentrating under reduced pressure, vacuum≤-0.07Mpa~-0.08Mpa, temperature≤70 ℃; To the extractum of relative density 1.10~1.35 (60 ℃ intermittent fever survey), filter, spray drying, drying condition be decided to be vacuum≤, temperature≤70 ℃ are dried to moisture<3%.Get extract.Standby.
Preferably, above-mentioned Chinese medicine formula be Herb Gynostemmae Pentaphylli 25kg, Fructus Lycii 15kg, Rhizoma Alismatis 10kg, Radix Ophiopogonis 10kg, Ganoderma 12kg, Fructus Crataegi 8kg, Flos Chrysanthemi 8kg, Flos Caryophylli 6kg, Rhizoma Polygoni Cuspidati 6kg, Folium Nelumbinis 6kg, Rhizoma Alismatis 6kg.
3., to get weight portion be 85~90% broken end of ANHUA HEI CHA and/or tea extracts, adds 15~10% integration of edible and medicinal herbs class article and/or extract, mixing, spray drying adds the adjuvant of appropriate capsule, mixing by known method, granulate, the capsule of packing into No. 1, and get final product.Co 60 sterilization, check, packing, warehouse-in.
The invention discloses a kind of postfermented tea compositions, and at the application product in field of losing weight, as health food, food, solid beverage or tablet, capsule, granule etc.Those skilled in the art can use for reference file content of the present invention and suitably improve, to realize other purpose.Special needs to be pointed out is, all are similarly replaced and change is very easy and apparent to one skilled in the art.Within they all should be deemed to be included in protection scope of the present invention.Method of the present invention and application are described by preferred embodiment, the related personnel can change methods and applications as herein described within not breaking away from content of the present invention, spirit and scope fully, or suitably changes with combination to realize and to use the present invention.

Claims (6)

1. postfermented tea compositions is by the ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, the black brick tea that contain FUCHA prime factor A, FUCHA prime factor B active component; Hua-juan tea such as thousand tael tea, hundred liang of tea; It point, to give birth to point, tribute sharp etc.), the integration of edible and medicinal herbs class article such as Herb Gynostemmae Pentaphylli, Rhizoma Alismatis, Radix Ophiopogonis make tea product, capsule, tablet or granule etc., all kinds of obese peoples are had fairly obvious, persistency fat-reducing and antihyperglycemic, and do not rebound.
2. a kind of postfermented tea compositions according to claim 1, and in the application in fat-reducing field, it is characterized in that: described ANHUA HEI CHA has referred to comprise following postfermented tea product category: FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It is sharp, life is sharp, tribute is sharp etc., contains its exclusive active component FUCHA prime factor A, FUCHA prime factor B active component in product.
3. a kind of postfermented tea compositions according to claim 1, and in the application in field of losing weight, it is characterized in that: described Chinese medicine formula composition comprises following article: Herb Gynostemmae Pentaphylli, Fructus Lycii, Rhizoma Alismatis, Radix Ophiopogonis, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Flos Caryophylli, Rhizoma Polygoni Cuspidati, Folium Nelumbinis, Rhizoma Alismatis, Semen Cuscutae, Fructus Ligustri Lucidi, Herba Ecliptae, Radix Polygoni Multiflori, Radix Et Rhizoma Rhei.
4. a kind of postfermented tea compositions according to claim 3, and in the application in field of losing weight, it is characterized in that: described Chinese medicine formula composition, preferred: Herb Gynostemmae Pentaphylli, Fructus Lycii, Rhizoma Alismatis, Radix Ophiopogonis, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Flos Caryophylli, Rhizoma Polygoni Cuspidati, Folium Nelumbinis, Rhizoma Alismatis.
5. a kind of postfermented tea compositions according to claim 1, and in the application in fat-reducing field, it is characterized in that: described production technology is:
1., take ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It point, to give birth to point, tribute sharp etc., is ground into 30~90 purpose broken ends, standby.
2. or, take ANHUA HEI CHA (FUZHUAN tea, ornamental slab for paving the floor tea, green brick tea, black brick tea; Hua-juan tea such as thousand tael tea, hundred liang of tea; It is sharp, life is sharp, tribute is sharp etc.) 300kg, drop in extraction pot, add the water of 6~16 times, extract under High Temperature High Pressure, get filtrate, filter, be evaporated to the extractum of relative density 1.05~1.40 (60 ℃ of intermittent fever are surveyed), filter, spray drying gets tea extract.Standby.
3., take above-mentioned integration of edible and medicinal herbs class article Herb Gynostemmae Pentaphylli, Fructus Lycii, Rhizoma Alismatis, Radix Ophiopogonis, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Flos Caryophylli, Rhizoma Polygoni Cuspidati, Folium Nelumbinis, Rhizoma Alismatis, Semen Cuscutae, Fructus Ligustri Lucidi, Herba Ecliptae, Radix Polygoni Multiflori, Radix Et Rhizoma Rhei, drop in extraction pot, the water that adds 8~12 times, extract under High Temperature High Pressure, get filtrate, filter concentrating under reduced pressure, vacuum≤-0.07Mpa~-0.08Mpa, temperature≤70 ℃; To the extractum of relative density 1.10~1.35 (60 ℃ intermittent fever survey), filter, spray drying, drying condition be decided to be vacuum≤, temperature≤70 ℃ are dried to moisture<3%.Get extract.
4., to get weight portion be 85~95% broken end of ANHUA HEI CHA and/or tea extracts, adds 5~25% integration of edible and medicinal herbs class article and/or extract, mixing, dry, make teabag by the processing technology of known teabag.Co 60 sterilization, check, packing, warehouse-in.
6. a kind of postfermented tea compositions according to claim 1, and in the application in fat-reducing field, it is characterized in that: product of the present invention can also be acceptable product form on the Food Sciences such as tablet, capsule, electuary, granule, solid beverage.
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CN101229279A (en) * 2008-01-23 2008-07-30 贺志弘 Collateral-dredging antihyperlipidemic product containing dark tea active substance and preparing method thereof
CN101244205A (en) * 2008-02-25 2008-08-20 贺志弘 Vein relaxing antihypelipidemic product based on reestablishment entatic state theory and preparation method
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CN103392876A (en) * 2013-07-29 2013-11-20 贺志弘 Jinfu clear tea and preparation method thereof
CN103843927A (en) * 2014-02-25 2014-06-11 湖南农业大学 Anti-radiation black tea beverage and preparation method thereof
CN103843927B (en) * 2014-02-25 2015-05-20 湖南农业大学 Anti-radiation black tea beverage and preparation method thereof
CN104938684A (en) * 2014-03-31 2015-09-30 湖南省怡清源茶业有限公司 Tea for assisting reduction of blood lipid and preparation method thereof
CN104719535A (en) * 2015-03-21 2015-06-24 湖南省天下武陵农业发展有限公司 Maca black tea composition capable of improving sub-health status of women and preparation method of maca black tea composition
CN104719536A (en) * 2015-03-21 2015-06-24 湖南省天下武陵农业发展有限公司 Maca dark green tea composition capable of improving the sub-health status of men and preparation method thereof
CN104996636A (en) * 2015-07-31 2015-10-28 何慧艳 Health-care flower tea and preparation method thereof
CN106473115A (en) * 2015-08-23 2017-03-08 祝杨 A kind of postfermented tea nourishing capsule
CN105104626A (en) * 2015-09-25 2015-12-02 贺志弘 Sweet dew brick tea composition and preparing method and application thereof
CN107174612A (en) * 2016-03-11 2017-09-19 王翠梅 A kind of four tastes clear liver and improve vision, lipid-loweringing blood circulation-promoting health health herb tea formula
CN107173479A (en) * 2016-03-11 2017-09-19 王翠梅 A kind of two tastes promote the production of body fluid cough-relieving health care's herb tea formula
CN107136244A (en) * 2016-07-28 2017-09-08 徐建俭 One kind promotes reducing blood lipid drink
CN106417756A (en) * 2016-09-27 2017-02-22 聂光永 Healthy tea
CN106490592A (en) * 2016-09-30 2017-03-15 湖南荷柏园电子商务有限公司 A kind of electuary powder with drop oils and fatss beautification function
CN106509226A (en) * 2016-11-11 2017-03-22 登封市老拴保肥料有限公司 Health-caring and health-preserving tea capable of greatly nourishing Qi and blood, benefiting intelligence and calming nerves
CN106509229A (en) * 2016-11-11 2017-03-22 登封市老拴保肥料有限公司 Health-preservation health-care tea capable of supplementing qi, invigorating spleen, replenishing blood and invigorating splenic yang
CN106509243A (en) * 2016-11-11 2017-03-22 登封市老拴保肥料有限公司 Health-preservation health-care tea capable of nourishing kidney, strengthening yang and strengthening tendons and bones
CN106509281A (en) * 2016-12-21 2017-03-22 神农架林区中医医院 campylandra chinensis sore-throat relieving tea and preparation method thereof
CN107212121A (en) * 2017-07-26 2017-09-29 陕西科技大学 A kind of gynostemma pentaphylla Fu-brick tea and preparation method thereof
CN107212122A (en) * 2017-07-26 2017-09-29 陕西科技大学 A kind of bark of eucommia gynostemma pentaphylla is combined Fu-brick tea and preparation method thereof
CN110810841A (en) * 2019-12-14 2020-02-21 湖南华莱生物科技有限公司 Green and lean Fuzhuan tea composition and preparation method thereof

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