CN104721414A - Gynostemma pentaphylla lipid-lowering tea - Google Patents
Gynostemma pentaphylla lipid-lowering tea Download PDFInfo
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- CN104721414A CN104721414A CN201410769740.1A CN201410769740A CN104721414A CN 104721414 A CN104721414 A CN 104721414A CN 201410769740 A CN201410769740 A CN 201410769740A CN 104721414 A CN104721414 A CN 104721414A
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Abstract
The invention discloses gynostemma pentaphylla lipid-lowering tea. Counted by 1000 bags of finished product with a specification of 3.0g/bag, the gynostemma pentaphylla lipid-lowering tea comprises 2.0kg of gynostemma pentaphylla, 1.0kg of hawthorn, 0.1kg of ginkgo leaf extract, 1.0kg of rhizoma alismatis, 0.5kg of semen cassiae, 0.5kg of lotus leaf, 0.4kg of wild pueraria, 0.3kg of prepared polygonum multiflorum and 0.3kg of fructus lycii. The gynostemma pentaphylla lipid-lowering tea disclosed by the invention adopts gynostemma pentaphylla as a sovereign drug, the main active component of gynostemma pentaphylla is saponin, and thus total saponin is determined as a marker component. The gynostemma pentaphylla lipid-lowering tea disclosed by the invention is a Chinese herbal medicine compound preparation, the components are complicated, polysaccharide is a shared component in various kinds of traditional Chinese medicines, so that crude polysaccharide is determined as a marker component to control the product quality. Animal function tests and human feeding tests prove that the gynostemma pentaphylla lipid-lowering tea disclosed by the invention has the health function of assisting to lower blood lipid.
Description
Technical field
The present invention relates to a kind of antihyperlipemic tea, refer in particular to a kind of Herb Gynostemmae Pentaphylli antihyperlipemic tea.
Background technology
After China's reform, along with improving constantly of people's living standard, the sickness rate of the affluence diseases such as hypertension, hyperlipidemia, coronary heart disease, diabetes, obesity also obviously rises thereupon, has caused the concern of the whole society.This kind of disease is the first killer threatening middle-aged and elderly people health, the disease that the dependencys such as hyperlipidemia, diabetes, obesity are very close, and it is added total incidence is 10%, considers compound predisposing factor, remains serious problem.
The traditional Chinese medical science is thought, though cream fat is the nutrient substance of human body, crosses and forms hyperlipidemia at most for suffering from.All to cause human body to take in cream fat too much, and cream fat transfers, utilizes, the factor of abevacuation all can make blood fat raise.
Modern Chinese medicine is thought from pathogenesis angle, and hyperlipemia belongs to motherland's medical science " expectorant is turbid ", " blood stasis " category.Its cause of disease is as follows:
(1) diet is improper: eating and drinking without temperance, hyperingestion, or throws off restraint the rich sweet savoury of food, and too much cream fat enters human body with diet, defeated cloth, transforms too late, and be detained in blood, thus blood fat raises.Chronic dietary is improper, or excessive drinking excessively, undermines taste, and strong fortune mistake department, causes diet not reforming, can not change precise and tiny in nutrition whole body, becomes raw fat on the contrary turbid, is mixed in blood, causes blood fat to raise.The former is excess syndrome, and the latter is deficiency complicated with excess card.
(2) liking quiet dynamic or natural disposition less likes quiet, and greedy sleeping is moved less; Or limit because of Job, bend over the desk all day, sit few walk, human functional activity of vital energy loses in dredging smooth, and then the defeated cloth of body fluid is unfavorable for the stagnation of QI.Cream fat trans-utilization is too late, so that raw multiplex few, and in lithosomic body, in contamination blood, therefore blood fat raises.
(3) emotional stimulation: worry impairing spleen, dysfunction of the spleen in transportation, or depressed rage impairing the liver, liver is lost bar and reaches, functional activity of QI being not smooth, and the defeated cloth of cream fat transporting is not normal, and blood fat raises.
(4) worn with age: people always then the vital organs of the human body all decline, based on kidney.Kidney master five liquid, suffers from a deficiency of the kidney, and body fluid loses it and dominates; The spleen has the function to transport and transform nutrients, insufficiency of the spleen, and diet is reforming not; Liver controlling conveyance and dispersion, the defeated cloth of the weak then body fluid of liver is unfavorable, and three all makes cream lipid metabolism not normal, causes blood fat to raise.If excess of sexual intercourse, painstaking worried, people end also can be made always and first to decline.
(5) physiques and natural endowment: father and mother are fat, greasiness since the childhood, after growing up, body is more plump, and how not enough yang-energy is often, and body fluid cream fat defeatedization is slow, and it is too much to educate matter in blood.Or ferritic hyperactivity of YANG due to deficiency of YIN, esterified for educating, dissolve in blood, blood fat raises.
(6) card such as to quench one's thirst, edema, hypochondriac pain, jaundice, disease are long-pending is not healed: it is scorching that diabete basic pathogenesis belongs to the deficiency of YIN, owing to disturbing in asthenic fire, and polyphagia due to stomach-heat, the normal polydipsia polyphagia of patient, but diet is precise and tiny can not become fat and preserve, and the fat of human body is anti-molten is to the greatest extent cream, be mixed in blood, cause blood fat to raise.With the passing of time edema, undermines spleen kidney, and suffering from a deficiency of the kidney can not main liquid, insufficiency of the spleenly loses in strong fortune, so that cream lipid metabolism is not normal.Hypochondriac pain, jaundice, disease amass the disease that three all belongs to liver, gallbladder, and hepatopathy mechanism of qi loses in catharsis, and the compress affecting cream fat transforms, and gallbladder disease can not turbidity fat only, causes blood fat to raise.
Hyperlipemia is divided into sputum to check type, yang deficiency of spleen and stomache, liver-kidney yin deficiency, type of deficiency of YIN leading to hyper activity of YANG, qi stagnation and blood stasis type 5 pattern of syndrome, and wherein sputum checks card group at most, and main manifestations is that triglyceride (TG) raises.
Summary of the invention
The object of the present invention is to provide a kind of Herb Gynostemmae Pentaphylli antihyperlipemic tea, to reach effective blood fat reducing and health care.
In order to reach above-mentioned purpose, solution of the present invention:
A kind of Herb Gynostemmae Pentaphylli antihyperlipemic tea, in finished product 1000 bags, specification 3.0g/ bag, its formula is:
Herb Gynostemmae Pentaphylli 2.0kg, Fructus Crataegi 1.0kg, Folium Ginkgo extract 0.1kg, Rhizoma Alismatis 1.0kg, Semen Cassiae 0.5kg, Folium Nelumbinis 0.5kg, Radix Puerariae 0.4kg, Radix Polygoni Multiflori Preparata 0.3kg, Fructus Lycii 0.3kg.
After adopting such scheme, the monarch drug that the present invention is this formula with Herb Gynostemmae Pentaphylli, the main active of Herb Gynostemmae Pentaphylli is Saponin, therefore determines that Total saponin is significant composition; The present invention is Chinese herbal compound preparation, and composition is comparatively complicated, and polysaccharide is the total composition of all kinds of Chinese medicine, therefore determines that crude polysaccharides is significant composition, so that control of product quality.The present invention proves through animal function test and human feeding trial, has the health care of auxiliary antilipemic.
Detailed description of the invention
A kind of Herb Gynostemmae Pentaphylli antihyperlipemic tea that the present invention discloses, in finished product 1000 bags, specification 3.0g/ bag, its formula is:
Herb Gynostemmae Pentaphylli 2.0kg, Fructus Crataegi 1.0kg, Folium Ginkgo extract 0.1kg, Rhizoma Alismatis 1.0kg, Semen Cassiae 0.5kg, Folium Nelumbinis 0.5kg, Radix Puerariae 0.4kg, Radix Polygoni Multiflori Preparata 0.3kg, Fructus Lycii 0.3kg.
In formula, the efficacy effect of each raw material, effective dose and safe edible dosage are as follows.
Herb Gynostemmae Pentaphylli, cold, bitter; Return lung, spleen, kidney channel.Tonify deficiency, heat clearing away, removing toxic substances.Weak for body void, nephrasthenia emission, leukopenia, hyperlipemia, viral hepatitis, chronic gastroenteritis, chronic tracheitis, Military Medical Science Institute connects the researchs such as cajaput and shows that Herb Gynostemmae Pentaphylli has obvious effect for reducing blood fat, within 7 weeks, hyperlipidemia is brought out when feeding high glucose and high fat feedstuff to rat, in blood, T-CHOL (TC) is 159.0 ± 19.0mg/dl, triglyceride (TG) mean concentration is 234.4 ± l8.1mg/dl, and in feedstuff, add Herb Gynostemmae Pentaphylli total glycosides 100mg/kg/d × 7 week, itself TC and TG is respectively 107.94 ± 8.8 and 153.6 ± 9.1mg/dl, difference is all very remarkable.When general glycoside amount is aggravated to 500mg/kg/d × 7 week, blood lipid level and normal group similar.Mice feeds high glucose and high fat feedstuff 7 weeks, causes obesity, fatty liver and body fat deposits, and when adding general glycoside l g/kg in feedstuff, the obviously reduction and close to normal group level such as body weight; Field Surgery Inst. of The Third Military Medical Univ. Wang Lin is beautiful waits research to show that Herb Gynostemmae Pentaphylli has obvious effect for reducing blood fat, Herb Gynostemmae Pentaphylli total glycosides can reduce high glucose and high fat diet, reduce T-CHOL and triglyceride content, SGOT is tending towards normal, lobules of liver steatosis is not obvious, hepatocyte is close to normal, and the higher adipose tissue of Changes of enzyme histochemistry GOP, ACP, NEase, ATPase activity is improved, and the lipid-lowering effect of low dose of Herb Gynostemmae Pentaphylli is more obvious than heavy dose of; Dai Hanyun etc. have studied the impact of Herb Gynostemmae Pentaphylli on various lipoprotein, result shows that Herb Gynostemmae Pentaphylli significantly can reduce the solid ferment (TC) of the total gallbladder of serum, low density lipoprotein, LDL (LDL), very low density lipoprotein (VLDL) (VLDL) content, improve high density lipoprotein (HDL) content, HDL/LDL ratio is increased.Qi Gang etc. study high fat mice and high fat quail Bo liver and atherosclerotic lesion impact, and result shows: Herb Gynostemmae Pentaphylli can suppress the solid ferment of gallbladder in high fat mice serum to some extent, the rising of triglyceride; The fat of high fat animal livers is become there is protective effect; this effect and its reduction blood fat, improve lipid metabolism and to lack of proper care direct relation; Herb Gynostemmae Pentaphylli 100mg/kg.d × 4wk gavage such as Cheng Rongzhen cheats medicine; experimental result shows that Herb Gynostemmae Pentaphylli can reduce the blood lipid level of Experimental Hyperlipoidemia Rabbits, can reduce the content of Serum LPO Levels and myocardium lipofuscin simultaneously.This product specification is 3.0g/ bag, day dose be 2 bags, containing Herb Gynostemmae Pentaphylli 4g.
Fructus Crataegi, sour, sweet, tepor.Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.Modern pharmacological research shows, the ethanol extraction of Fructus Crataegi can reduce the content of hyperlipemia rat cholesterol in serum, triglyceride and low-density lipoprotein cholesterol, raises the content of rat blood serum middle-high density lipoprotein cholesterol.The ursolic acid extracted in Fructus Crataegi and hyperin have mice high blood lipid model and obviously reduce total cholesterol level, strengthen the activity of high density lipoprotein and SOD.Compound haw thorn electuary has the effect reducing hyperlipemia laboratory animal fatty liver and formed." Chinese Pharmacopoeia " 2010 editions specified volumes are 9 ~ 12g, and this product specification is 3.0g/bag, day dose be 2 bags, containing Fructus Crataegi 2.0g.
Folium Ginkgo extract function and Folium Ginkgo similar, sweet, bitter, puckery, flat.GUIXIN, lung meridian.Astringe the lung, relieving asthma, blood circulation promoting and blood stasis dispelling, pain relieving.For cough and asthma due to lung deficiency; Coronary heart disease, angina pectoris, hyperlipidemia, anticoagulant is solid, has certain probability to improve memory.Modern pharmacological research shows, this product can be used for cough and asthma due to lung deficiency and hyperlipidemia, hypertension, coronary heart diseases and angina pectoris, cerebral vasospasm etc.This product conventional amount used is 9 ~ 12g, and this product specification is 3.0g/ bag, day dose be 2 bags, composition containing ginkgo leaf extract 0.2g, is converted to Folium Ginkgo and is about 2.0g.
Rhizoma Alismatis, sweet, cold.Return kidney, urinary bladder channel.Diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.Modern pharmacological research shows, this product has effect for reducing blood fat and study of anti-atherogenic effect." Chinese Pharmacopoeia " 2010 editions specified volumes are 6 ~ 9g, and this product specification is 3.0g/bag, day dose be 2 bags, containing Rhizoma Alismatis 2.0g.
Semen Cassiae, sweet, bitter, salty, be slightly cold.Return liver, large intestine channel.Clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation." Chinese Pharmacopoeia " 2010 editions specified volumes are 9 ~ 15g, and this product specification is 3.0g/bag, day dose be 2 bags, containing Semen Cassiae 1.0g.
Folium Nelumbinis is bitter, flat.Return liver, spleen, stomach warp.Clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, metrorrhagia of having blood in stool." Chinese Pharmacopoeia " 2010 editions specified volumes are 3 ~ 9g, and this product specification is 3.0g/bag, day dose be 2 bags, containing Folium Nelumbinis 1.0g.
Radix Puerariae is sweet, pungent, cool.Return spleen, stomach warp.Expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain." Chinese Pharmacopoeia " 2010 editions specified volumes are 9 ~ 15g, and this product specification is 3.0g/ bag, day dose be 2 bags, containing Radix Puerariae 0.8g.
Radix Polygoni Multiflori Preparata is bitter, sweet, puckery, temperature.Return liver, the heart, kidney channel.Removing toxic substances, eliminating carbuncle, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia." Chinese Pharmacopoeia " 2010 editions specified volumes are 6 ~ 12g, and this product specification is 3.0g/bag, day dose be 2 bags, containing Radix Polygoni Multiflori Preparata 0.6g.
Fructus Lycii is sweet, flat.Return liver, kidney channel.Nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand." Chinese Pharmacopoeia " 2010 editions specified volumes are 6 ~ 12g, and this product specification is 3.0g/bag, day dose be 2 bags, containing Fructus Lycii 0.6g.
The present invention is made up of 9 taste medicines, Herb Gynostemmae Pentaphylli in side, cold, bitter; Return lung, spleen, kidney channel, modern pharmacological research shows that Herb Gynostemmae Pentaphylli has obvious effect for reducing blood fat; Fructus Crataegi, sour, sweet, tepor.Return spleen, stomach, Liver Channel, promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, modern pharmacological research shows, the ethanol extraction of Fructus Crataegi can reduce the content of hyperlipemia rat cholesterol in serum, triglyceride and low-density lipoprotein cholesterol, raises the content of rat blood serum middle-high density lipoprotein cholesterol; Rhizoma Alismatis, sweet, cold, return kidney, urinary bladder channel, diuresis, clearing away damp-heat, for dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia, modern pharmacological research shows, this product has effect for reducing blood fat and study of anti-atherogenic effect, and three medicines are monarch drug altogether; Folium Ginkgo extract function and Folium Ginkgo similar, sweet, bitter, puckery, flat.Astringe the lung, relieving asthma, blood circulation promoting and blood stasis dispelling, pain relieving; Folium Nelumbinis bitter in the mouth, puckery, property is put down, can clearing away summer-heat and eliminating dampnessization turbid; Two medicines reduce phlegm turbid, and dissipating blood stasis is stagnant, are ministerial drug altogether; Semen Cassiae, sweet, bitter, salty, be slightly cold, clearing away heat to improve acuity of vision, loosening bowel to relieve constipation; Radix Puerariae is sweet, pungent, cool.Expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, and Radix Polygoni Multiflori Preparata is bitter, sweet, puckery, temperature, removing toxic substances, eliminating carbuncle, loosening bowel to relieve constipation, and promoting the defeated cloth of cream fat in body, conversion, is adjuvant drug; Fructus Lycii is sweet, flat, nourishing the liver and kidney, and kidney master five liquid, suffers from a deficiency of the kidney, and body fluid loses it and dominates, and liver controlling conveyance and dispersion, the defeated cloth of the weak then body fluid of liver is unfavorable, and this taste medicine can promote cream lipid metabolism, and for making medicine, all medicines match, and amount to the merit that blood fat reducingization is turbid.
Fructus Crataegi used herein, Semen Cassiae, Folium Nelumbinis, Radix Puerariae, Fructus Lycii be Ministry of Public Health defend method prison send out specify in (2002) No. 51 files be food and the article of medicine; Herb Gynostemmae Pentaphylli, Rhizoma Alismatis, the lotus Radix Polygoni Multiflori processed are that Ministry of Public Health defends the article that can be used for health food specified in method prison (2002) No. 51 files; The stock silver Folium Pruni of Folium Ginkgo extract is that Ministry of Public Health is defended method prison and sent out the article that can be used for health food specified in (2002) No. 51 files, consumption per day does not all exceed " Chinese Pharmacopoeia " 2010 editions specified volumes and traditional consumption per day, thus edible be safe.
Health care of the present invention is auxiliary antilipemic, and by regulation in " health care and corresponding suitable population, the crowd that is not suitable for show ", suitable population of the present invention is Hyperlipidemia person, and the crowd that is not suitable for is children, pregnancy period and women breast-feeding their children.
Eating method and amount: every day 2 times, each 1 bag, boiling water brews, and drinks after after 5-8 minute, can steep several times of drinking to lightly seasoned.
The present invention proves through animal function test and human feeding trial, has the health care of auxiliary antilipemic.
Above-described embodiment non-limiting product form of the present invention and style, any person of an ordinary skill in the technical field, to its suitable change done or modification, all should be considered as not departing from patent category of the present invention.
Claims (1)
1. a Herb Gynostemmae Pentaphylli antihyperlipemic tea, it is characterized in that in finished product 1000 bags, specification 3.0g/ bag, formula is:
Herb Gynostemmae Pentaphylli 2.0kg, Fructus Crataegi 1.0kg, Folium Ginkgo extract 0.1kg, Rhizoma Alismatis 1.0kg, Semen Cassiae 0.5kg, Folium Nelumbinis 0.5kg, Radix Puerariae 0.4kg, Radix Polygoni Multiflori Preparata 0.3kg, Fructus Lycii 0.3kg.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106578185A (en) * | 2015-10-19 | 2017-04-26 | 屈涛 | Jiangjunhong blood fat lowering tea and preparation method thereof |
| CN109329689A (en) * | 2018-11-12 | 2019-02-15 | 天津市农业生物技术研究中心 | A kind of health solid beverage and preparation method thereof |
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| CN102423381A (en) * | 2011-12-30 | 2012-04-25 | 苏州爱斯欧蒂生物科技有限公司 | Health tea with fat-reducing efficacy |
| CN102961525A (en) * | 2012-11-20 | 2013-03-13 | 西安泰科迈医药科技有限公司 | Medicine composition for losing weight and reducing blood lipid in auxiliary manner and oral liquid preparation method thereof |
| CN103251043A (en) * | 2012-03-23 | 2013-08-21 | 山东德圣医药科技有限公司 | Auxiliary hypolipidemic health-care food |
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- 2014-12-15 CN CN201410769740.1A patent/CN104721414A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1839702A (en) * | 2005-04-03 | 2006-10-04 | 钟锦习 | Compound Gynostemma pentaphylla tea for assisting invigorating brain and heart and its preparation method |
| CN102423381A (en) * | 2011-12-30 | 2012-04-25 | 苏州爱斯欧蒂生物科技有限公司 | Health tea with fat-reducing efficacy |
| CN103251043A (en) * | 2012-03-23 | 2013-08-21 | 山东德圣医药科技有限公司 | Auxiliary hypolipidemic health-care food |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106578185A (en) * | 2015-10-19 | 2017-04-26 | 屈涛 | Jiangjunhong blood fat lowering tea and preparation method thereof |
| CN109329689A (en) * | 2018-11-12 | 2019-02-15 | 天津市农业生物技术研究中心 | A kind of health solid beverage and preparation method thereof |
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Application publication date: 20150624 |