CN106177786A - A kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) and preparation method thereof - Google Patents

A kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) and preparation method thereof Download PDF

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Publication number
CN106177786A
CN106177786A CN201610730041.5A CN201610730041A CN106177786A CN 106177786 A CN106177786 A CN 106177786A CN 201610730041 A CN201610730041 A CN 201610730041A CN 106177786 A CN106177786 A CN 106177786A
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radix
chinese medicine
kilograms
parts
rhizoma
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李山
李荣煌
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Guangdong Red Emperor Life Science & Technology Co Ltd
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Guangdong Red Emperor Life Science & Technology Co Ltd
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    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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Abstract

The invention discloses a kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) and preparation method thereof, belonging to treating AIDS technical field, this Chinese medicine composition is mainly made up of the raw material of Chinese medicine of following weight parts: Cordyceps 5 10 parts, Radix Codonopsis 15 30 parts, the Radix Astragali 15 30 parts, 5 15 parts of Lentinus Edodes, Rhizoma Curcumae 10 20 parts, Radix Angelicae Sinensis 5 15 parts, the Rhizoma Atractylodis Macrocephalae 10 20 parts, Arillus Longan 5 15 parts, Fructus Corni 10 20 parts, Bulbus Fritillariae Thunbergii 10 20 parts, Semen Ziziphi Spinosae (parched) 15 30 parts, Radix Ophiopogonis 10 18 parts, Concha Ostreae 10 25 parts, Radix et Rhizoma Rhei (stir-fried with wine) 10 20 parts, 10 25 parts of Radix Rehmanniae Preparata and Semen Cuscutae 10 15 parts;It is desirable to provide the Chinese medicine composition of a kind of low cost, side effect is little and therapeutic effect is good treatment acquired immune deficiency syndrome (AIDS);For treating AIDS.

Description

A kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) and preparation method thereof
Technical field
The present invention relates to a kind of medicine treating acquired immune deficiency syndrome (AIDS), more specifically, particularly relate to a kind for the treatment of in acquired immune deficiency syndrome (AIDS) Drug composition.The present invention also relates to the preparation method of this Chinese medicine composition.
Background technology
Acquired immune deficiency syndrome (AIDS) is a kind of great infectious disease of hazardness, aids infection virus (inhibition of HIV) cause.HIV is one Plant the virus that can attack human immune system.It using CD4T lymphocyte most important in human immune system as primary challenge Target, this cell of considerable damage, make human body lose immunologic function.Therefore, human body is prone to infect various disease, and can occur pernicious Tumor, case fatality rate is higher.HIV average out to 8~9 years incubation period in human body, before suffering from acquired immune deficiency syndrome (AIDS), can not have any symptom Ground live and work is for many years.The active drug of radical cure HIV is still lacked at present in worldwide.The treatment mesh of present stage Mark is: to greatest extent with lasting reduction virus load;Adaptive immune reconstruction and maintenance immunologic function;Improve life matter Amount;Reduce the relevant M & M of HIV.Comprehensive Treatment is emphasized in the treatment of primary disease, including: general treatment, antiviral are controlled Treat, recover or improve the treatment of immunologic function and opportunistic infection and the treatment of malignant tumor.And it is currently used for the medicine for the treatment of It mostly is Western medicine, although Western medicine effect is rapid, but easily occurs that untoward reaction makes the quality of life of patient decline, drug resistance is occurred to early Property selects to be restricted during anti-AIDS drug after making.Prior, it is susceptible to the propagation of drug-resistant virus.Western medicine ends Grow disease, there is the shortcoming that side effect is big, easily occur headache, feel sick, erythra, insomnia and the problems such as health is tired.
The traditional Chinese medical science is said: eliminating evil, righting, consolidate.Healthy energy is sufficient, and heresy can not be invaded, and healthy energy foot, all kinds of diseases and ailments disappear.So-called healthy energy, it is simply that immunity System, when human immune system enhances, various diseases just can not be invaded or all kinds of diseases and ailments disappear.
Summary of the invention
The previous purpose of the present invention is for above-mentioned the deficiencies in the prior art, it is provided that a kind of low cost, side effect little and The Chinese medicine composition of the treatment acquired immune deficiency syndrome (AIDS) that therapeutic effect is good.
The latter purpose of the present invention is to provide a kind of method preparing above-mentioned Chinese medicine composition.
The previous technical scheme of the present invention is achieved in that a kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS), this Chinese drug-treated group Compound is mainly made up of the raw material of Chinese medicine of following weight parts: Cordyceps 5-10 part, Radix Codonopsis 15-30 part, Radix Astragali 15-30 part, perfume (or spice) Mushroom 5-15 part, Rhizoma Curcumae 10-20 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Arillus Longan 5-15 part, Fructus Corni 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part, Semen Ziziphi Spinosae (parched) 15-30 part, 10-18 part Radix Ophiopogonis, Concha Ostreae 10-25 part, Radix et Rhizoma Rhei (stir-fried with wine) 10-20 part, Radix Rehmanniae Preparata 10-25 part and Semen Cuscutae 10-15 part.
In above-mentioned a kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS), this Chinese medicine composition also includes the Chinese medicine of following weight parts Raw material: Cortex Eucommiae(processed with salt) 10-18 part, Fructus Schisandrae Chinensis 10-20 part, Radix Paeoniae Alba 10-20 part, Rhizoma Pinelliae Preparata 5-15 part, Rhizoma Chuanxiong 10-18 part, Pericarpium Citri Reticulatae 5- 13 parts, Fructus Amomi 5-15 part and Radix Aucklandiae 5-18 part.
In above-mentioned a kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS), this Chinese medicine composition also includes the Chinese medicine of following weight parts Raw material: stir-baked RHIZOMA CORYDALIS with vinegar 10-25 part, Radix Glycyrrhizae 5-20 part, Poria cum Radix Pini's 10-18 part, Fructus Mume 5-15 part and Japanese raisintree fruit 10-18 part.
In above-mentioned a kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS), this Chinese medicine composition also includes the Chinese medicine of following weight parts Raw material: Rhizoma Anemarrhenae 5-15 part, Cornu Bubali 10-20 part, Cortex Phellodendri 5-15 part.
The latter technique scheme of the present invention is achieved in that the side of a kind of Chinese medicine composition preparing treatment acquired immune deficiency syndrome (AIDS) Method, the method comprises the steps:
(1) weigh the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine) by formulation weight part, after pulverizing in the water temperature of 60-80 DEG C water Carrying twice, medical material is 1:6-9 with the mass ratio of water, after twice gained extracting solution mixing, is incubated 4-5 hour, and then vacuum is dense Contract to obtain A concentrated solution;(2) weighing residue raw material of Chinese medicine by formulation weight part, after pulverizing, water carries twice, water temperature 80-100 DEG C, medical material It is 1:4-8 with the mass ratio of water, after twice gained extracting solution mixing, under room temperature, stands 1-2 hour, B concentration is concentrated in vacuo to obtain Liquid;(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.1-1.5 with the volume ratio of B concentrated solution;(4) After oral liquid is used conventional method packaging and sterilizing, make finished product.
The method of the Chinese medicine composition of above-mentioned preparation treatment acquired immune deficiency syndrome (AIDS), when raw material of Chinese medicine also includes Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, When Fructus Amomi and the Radix Aucklandiae, Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi and the Radix Aucklandiae are carried out water together with the Chinese crude drug in step (1) and carries.
The method of the Chinese medicine composition of above-mentioned preparation treatment acquired immune deficiency syndrome (AIDS), when also including stir-baked RHIZOMA CORYDALIS with vinegar and sweet in raw material of Chinese medicine During grass, stir-baked RHIZOMA CORYDALIS with vinegar and Radix Glycyrrhizae are carried out water together with the Chinese crude drug in step (1) and carries.
The method of the Chinese medicine composition of above-mentioned preparation treatment acquired immune deficiency syndrome (AIDS), in step (1), described in be concentrated in vacuo as at 50- Under the temperature environment of 70 DEG C, the volume ratio being concentrated in vacuo between water and extract is 1:1.3-2.2, obtains A concentrated solution.
The method of the Chinese medicine composition of above-mentioned preparation treatment acquired immune deficiency syndrome (AIDS), in step (2), described in be concentrated in vacuo as at 50- Under the temperature environment of 70 DEG C, the volume ratio being concentrated in vacuo between water and extract is 1:1.5-2.0, obtains B concentrated solution.
Below the property of medicine of Chinese medicine each in formula is illustrated:
Cordyceps, sweet in the mouth, property are flat, nontoxic.Enter lung, kidney channel.
Effect: there is tonifying deficiency, benefit vital essence, tonifying the lung tonifying YANG.Control dyspnea due to deficiency, cough spitting of blood, spontaneous sweating, sexual impotence something lost Essence, soreness of waist and knee joint, sick void, pulmonary tuberculosis, anemia;All hyperactivity of YANG due to deficiency of YIN and cough, deficiency-distension, the panacea of empty pain;It is empty that Cordyceps has temperature The property of flat benefit, for malaria stuffy sensation of deftciency type, deficiency-distension, the panacea of empty pain.There is the wonderful of interdependence between yin and yang, the void that tonifying the lung kidney two is dirty, improve cell Immunologic function, has the most relieving convulsion, convulsion, promotion organism metabolism function.
Radix Codonopsis, sweet in the mouth, property is put down.
Effect: invigorating the spleen and replenishing QI, stomach function regulating promotes the production of body fluid, expelling phlegm for arresting cough.For insufficiency of the spleen anorexia and loose stool, myasthenia of limbs, cardiopalmus, gas Short, xerostomia, spontaneous perspiration, proctoptosis, the prolapse of the uterus.
The Radix Astragali, sweet in the mouth, warm in nature.Return lung, spleen channel.
Function cures mainly: QI invigorating invigorating middle warmer.Weak for the deficiency of vital energy, anorexia and loose stool.Typically merge use with Radix Codonopsis etc., be mainly used in QI invigorating is used.
Rhizoma Curcumae, acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.
Effect: (1) removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, accumulation, woman Female's blood stasis amenorrhea, traumatic injury is had a pain eating accumulation.(2) promoting the circulation of QI to relieve pain, removing blood stasis removing food stagnancy: for amenorrhea, the breast side of body of qi depression to blood stasis Bitterly, stomachache and lump in the abdomen lump etc..Often join Rhizoma Sparganii.(3) promoting digestion and removing stagnation: for the stomach abdominal distention and pain of eating accumulation, often join Fructus Hordei Germinatus (parched to brown), Jiao Semen Arecae.
Radix Angelicae Sinensis, sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.
Effect: enrich blood;Invigorate blood circulation;Menstruction regulating and pain relieving;Moisturize laxation.The all cards of main blood deficiency;Menoxenia;Amenorrhea;Dysmenorrhea;Disease Abdominal mass knot is poly-;Metrorrhagia;Asthenia cold abdominalgia;Flaccidity syndrome and arthralgia syndrome;Numbness of the skin;Dryness of the intestine dyschezia;Weight after bloody dysentery;Ulcer sores;Injury from falling down.
Fructus Corni is sour in the mouth, puckery, slightly warm in nature, nontoxic.Return liver, kidney channel.There is liver and kidney tonifying, essence astringing and desertion stemming, benefit Yuanyang, mend Vigour, primordial QI reinforcing essence, primordial qi strengthening siddhi energy;Cure mainly the vertigo, waist cold type of pain, impotence and premature ejaculation, frequent urination and enuresis, spontaneous sweating, deficiency of the liver Cold and heat, incessant sweating due to debility, take a tonic or nourishing food to build up one's health Liver and kidney, with Yi Qiyuan, Psoralen marrow, vital essence is not let out.Liver and kidney is the weakest, is the pathogenic base of " hot body " Cause;Fructus Corni directly enters Liver and kidney, can invigorating the liver and kidney, can mend again Tianyuan, two-way effect of primordial qi strengthening siddhi effect, adapted Cordyceps, for The monarch drug of benefit is adjusted in " hot body " post-equalization;
The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.
Effect: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, Edema, spontaneous perspiration, frequent fetal movement.
The Radix Paeoniae Alba is bitter in the mouth, acid, cold nature, nontoxic.Return liver, spleen channel.
Effect: there is removing fire from the liver, suppressing liver-YANG, yin nourishing relieving restlessness, yin fluid astringing of enriching blood, easing the affected liver and spleen analgesic efficacy.Cure mainly Breast side of body abdominal distention caused by disharmony in liver-QI, woman in menstrual period imbalance etc..Radix Paeoniae Alba (parched) is also known as Radix Paeoniae Alba (processed).For Radix Paeoniae Alba sheet bran with slow fire Frying to micro-Huang, slightly focal spot, sieve removes Testa Tritici, the cool person of being used as medicine of drying in the air.
Arillus Longan, i.e. Arillus Longan, sweet in the mouth warm in nature, enter the heart, spleen channel;
Effect: invigorating the heart and spleen, nourishing blood to tranquillize the mind.For insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.
Bulbus Fritillariae Thunbergii, bitter in the mouth, sweet, cold nature.Return lung, heart channel.Function cures mainly: this product bitter in the mouth, cold nature, returns lung meridian, available Breathe heavily in treatment expectorant heat syndrome cough, yellow thick card of coughing up phlegm;Hold concurrently again sugariness, therefore kind nourishing the lung to arrest cough, treatment lung has scorching cough expectorant few and viscous Card, and deficiency syndrome such as deficiency of YIN cough caused by dryness chronic cough;Also have the merit of eliminating stagnation dissipating depression of QI, treat the uncomfortable in chest vexed card caused by combination of phlegm and heat, and The diseases such as scrofula sucutaneous nodule.Additionally, Bulbus Fritillariae Cirrhosae and Os Sepiae, Radix Glycyrrhizae are powder, i.e. Medicinal powder of cuttlefish and firtillary bulb, treatment gastric ulcer is effective.
Semen Ziziphi Spinosae (parched), sweet in the mouth, acid, property is flat, nontoxic.Enter the heart, liver, gallbladder meridian.
Effect: there is tonifying liver, effect that mind calming, arresting sweating, mercy of promoting the production of body fluid are calmed the nerves.Control the palpitation and amnesia of insufficiency of blood of having a guilty conscience, Insomnia and dreamful sleep, thirst due to body fluid deficiency etc..
Radix Rehmanniae Preparata, sweet in the mouth, slightly warm in nature.Return liver, kidney channel.
Effect: have YIN nourishing effect of enriching blood, can be used for blood deficiency and yellow complexion, dizziness, palpitation and insomnia, menoxenia, metrorrhagia Deng disease, also can be used for deficiency of kidney yin hectic fever hectic fever due to YIN-deficiency, night sweat, pass out semen, the disease such as quench one's thirst, be deficiency syndrome class nonprescription drugs medicine Six-element ground One of yellow ball main component.
Radix Ophiopogonis, sweet in the mouth, micro-hardship, cold nature, return stomach, lung, heart channel.
Effect: have nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the effect of the relieving restlessness that clears away heart-fire, coughs for dryness of the lung dry cough, deficiency of YIN consumptive disease, larynx The diseases such as numbness pharyngalgia, Tianjin wound are thirsty, interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Semen Cuscutae, sweet in the mouth, warm in nature, return kidney,liver,spleen warp.
Effect: Semen Cuscutae is the good medicine put down simply and mend kidney,liver,spleen, and clinic is mainly used in lumbago due to renal deficiency, sexual impotence is lost Essence, frequent micturition, cold womb are infertile, the kidney yin yang deficiency syndrome of the dark loose stool of mesh.Semen Cuscutae is sweet, warm, returns kidney,liver,spleen warp, have nourishing the liver and kidney, Controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, effect of antidiarrheal, begin to carry Shennong's Herbal, be listed in top grade.Sugariness typically has nourishing and makees By, sweet pungent tepor, report gas and neutralize, both can YANG invigorating, again can tonifying YIN, there is temperature and the driest, mend and the most stagnant feature.
Concha Ostreae, salty in the mouth, cold nature;Return liver, gallbladder, kidney channel.
Effect: there is tonifying YIN YANG hyperactivity suppressing, tranquillizing the mind by relieving convulsion, the de-solid merit of convergence.Control consumption of YIN caused by febrile disease, stirring-up of pathogenic wind in the interior resulting from deficiency, cardiopalmus Insomnia, tranquillizing the mind by relieving convulsion.
Radix et Rhizoma Rhei (stir-fried with wine), bitter in the mouth, cold in nature.Return stomach, spleen, large intestine, liver, heart channel.
Effect: have purging heat to relax the bowels effect, constipation, abdominal part distension, pain stagnant for Gastrointestinal excess heat are refused Press, even hyperpyrexia, unconsciousness and delirium, such as DACHENGQI TANG;Or the cold accumulation and constipation of spleen YANG deficiency, such as wenpi decoction.Removing toxicity for eliminating carbuncles merit Effect, for pathopyretic ulcer, sudden and violent acute conjunctivitis pain, aphtha of the mouth and tongue, gingivitis, such as Dahuang Mudan skin soup.Clots absorbing stimulates the menstrual flow effect, for the stasis of blood The menstruation apolipsis of blood retardance, postpartum stagnation, lump in the abdomen, and traumatic injury, swelling and pain due to blood stasis.Removing damp-heat effect, for damp and hot Stop up stagnant jaundice, dysuria, constipation with dry stool;Pyretic stranguria, stranguria caused by urinary stone such as BAZHENG SAN.Also can cooling blood for hemostasis, telling for injury of blood collaterals by heat Blood, epistaxis, have blood in stool, metrorrhagia, leucorrhea with red and white discharge.Modern clinic can be used for treating epidemic cerebrospinal meningitis, lobar pneumonia, acute biliary tract Infection, acute parotitis, acute appendicitis, Fiedeler's disease type hepatitis, acute enteritis, bacillary dysentery, digestion are said Blood, pharyngolaryngitis, gingival abscess, dermatitis, eczema, gonorrhea, herpes zoster etc..Radix et Rhizoma Rhei (processed) rushes down exerts oneself to delay, eliminating fire and detoxication.For fire-toxin Skin infection, vital QI being weakened and pathogen being violent is demonstrate,proved.
Rhizoma Dioscoreae, sweet in the mouth, property is flat, nontoxic.Return spleen, lung, kidney channel.
Effect: spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.Insufficiency of the spleen, chronic diarrhea, the deficiency of the lung, suffer from a deficiency of the kidney, leukorrhagia, frequent micturition.
The Cortex Eucommiae, sweet in the mouth, warm in nature, nontoxic, acrid in the mouth is flat.Return liver, kidney channel.
Effect: have invigorating the liver and kidney, controls spinal column ache, foot and knee flaccidity, dribbling urination, and uncontrolled urination is itched, hypertension, antiabortive Effect.Immune system, hormonal system, central nervous system, blood circulation and urinary system are had in various degree by the Cortex Eucommiae Regulation effect, the Cortex Eucommiae can excited Pituitary Adrenalcortical system, adrenal cortex reinforcing function.
Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.
Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
The Radix Aucklandiae, acrid in the mouth, hardship;Warm in nature.Return spleen, large intestine, tri-jiao channel.
Effect: circulation of qi promoting, pain relieving, spleen invigorating, help digestion.Cure mainly: promoting the circulation of QI to relieve pain;Intestinal stasis relieving in tune.Main born of the same parents coerce distension foot;Gastral cavity abdominal distention Bitterly;Tell and have loose bowels;Weight after dysentery.Weigh after breast gastral cavity distending pain, dysentery, food stagnation does not disappears, anorexia;Middle gas does not saves;Burst ear Deaf;Snake bite and insect sting;Toothache.
Lentinus Edodes, sweet in the mouth, property is put down, is returned stomach, Liver Channel.
Effect: (1) improves body's immunity: lentinan can improve the phagocytosis merit of Turnover of Mouse Peritoneal Macrophages Can, may additionally facilitate the generation of T lymphocyte, and improve the killing activity of T lymphocyte.It is demonstrated experimentally that possibly together with one in Lentinus Edodes Plant the Interferon Inducer of antiviral, human disease resistance can be improved, the diseases such as influenza can be prevented.Lentinus Edodes have stomach function regulating, Spleen invigorating, effect of QI invigorating kidney tonifying, can control the diseases such as the prolonged illness deficiency of vital energy, inappetence.
(2) slow down aging: the water extract of Lentinus Edodes has scavenging action to hydrogen peroxide, has necessarily internal hydrogen peroxide Elimination effect.
(3) cancer-resisting: Lentinus Edodes fungus cover contains the ribonucleic acid of duplex structure, after entering human body, can produce and have The interferon of antitumaous effect.
(4) lowering blood pressure and blood fat, cholesterol reducing: containing purine, choline, tyrosine, oxidase and some core in Lentinus Edodes Acid substance, can play the effect of blood pressure lowering, cholesterol reducing, blood fat reducing, again can the disease such as prevention of arterial hardening, liver cirrhosis.
(5) diabetes, pulmonary tuberculosis, infectious hepatitis, neuritis etc. are also played therapeutical effect by Lentinus Edodes, can be used for again digesting not Good, constipation etc..Additionally, nucleic acid material contained by Lentinus Edodes, also there is the function preventing and treating AIDS.
Fructus Amomi, acrid in the mouth, warm in nature.Return spleen, stomach, kidney channel.
Effect: during circulation of qi promoting is adjusted, stomach function regulating, it is amusing.Control stomachache painful abdominal mass swollen, anorexia dyspepsia, dysphagic vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant It is pregnent fetal movement.
Rhizoma Pinelliae Preparata, acrid in the mouth, warm in nature.Return spleen, stomach, lung meridian.
Function cures mainly: drying dampness to eliminate phlegm.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache.
Fructus Schisandrae Chinensis
Sour in the mouth is warm in nature, enters lung, kidney, heart channel.
Effect: astringe the lung, nourishing kidney, promote the production of body fluid, receive antiperspirant, arresting seminal emission.Controlling the deficiency of the lung to breath with cough, xerostomia is made thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain Weakness and emaciation, emission, chronic diarrhea chronic dysentery.
Rhizoma Chuanxiong, pungent, temperature.Enter liver, gallbladder meridian.
Effect: activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache rotation dizzy, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, Amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass suffers from abdominal pain, breast side of body twinge, fall flutter swollen Bitterly, headache, rheumatic arthralgia.
Fructus Mume, sour in the mouth, puckery, property is put down.Return liver, spleen, lung, large intestine channel.
Effect: astringe the lung, astringing intestine to stop diarrhea, promote the production of body fluid, relieving colic caused by ascaris.Curing mainly: for chronic cough of deficiency lung, chronic diarrhea chronic dysentery, deficiency-heat is quenched one's thirst, and the ascariasis of biliary tract vomits Stomachache.
Radix Glycyrrhizae, sweet in the mouth, property is put down;GUIXIN, lung, spleen, stomach warp.
Effect: there is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.For Weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, Strong.
Stir-baked RHIZOMA CORYDALIS with vinegar, warm in nature, acrid in the mouth is bitter, enters the heart, spleen, liver, lung.
Function cures mainly: for whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia Gas is had a pain.It is decocted in water for oral dose.
Poria cum Radix Pini, sweet light, flat.Enter the heart, spleen channel.
Effect: have mind calming, calm the nerves, the merit of diuretic.Poria cum Radix Pini, its body is heavy, mental disorder may be cured with heavy sedatives, its benefit warm in nature, happily Fructus Alpiniae Oxyphyllae, spasmolytic is throbbed with fear.Cure mainly palpitation with fear of having a guilty conscience, forgetful, tic difficulty in urination of having a sleepless night, have a guilty conscience and breathe hard, invigorating spleen to remove dampness, insufficiency of blood of having a guilty conscience, asthenia Fidgety insomnia, insufficiency of heart-QI is timid, mental derangement, and severe palpitation of palpitating with fear, labor is timid forgetful, the replenishing vital QI with drugs of warm nature mind.
Japanese raisintree fruit, sweet in the mouth acid, property is put down, nontoxic.Enter spleen, stomach warp.
Effect: control drunk, dysphoria with smothery sensation, thirsty, vomiting, difficulty in urination and defecation.Trifoliate orange contains substantial amounts of glucose, malic acid Calcium, has stronger diuresis, can promote decomposition and the discharge of ethanol, significantly reduces ethanol concentration in blood, and can disappear The free radical produced in vivo except ethanol, stops the formation of Metabolism of Lipoprotein-cholesterol, thus alleviates the ethanol damage to hepatic tissue, it is to avoid Alcoholism causes various Developmental and Metabolic Disorder, induces various disease.The traditional Chinese medical science is thought, trifoliate orange nature and flavor are sweet, flat, enter spleen, stomach warp, have and relieve the effect of alcohol The merit quenched the thirst, ancient Chinese medicine doctor is always with for key medicine of quenching the thirst of relieving the effect of alcohol, it is adaptable to insobriety, drunk does not wakes up, xerostomia excessive thirst, and disappears Thirsty etc..
The Rhizoma Anemarrhenae is sweet in the mouth, hardship, cold in nature, nontoxic.Return lung, stomach, kidney channel.
Effect: have clearing away heat-fire, promotes the production of body fluid and moisturizes, the fire of eliminating the pathogens from the lung stomach, nourishing YIN to lower pathogenic fire effect.Cure mainly fever caused by exogenous pathogenic factors, Lung-heat type cough, dryness of the intestine constipation, the hepatic and renal YIN deficiency, hyperactivity of deficient fire, night sweat seminal emission, high fever excessive thirst.
Cornu Bubali is sweet in the mouth, cold, nontoxic.
Effect: have heat-clearing and toxic substances removing, relieving palpitation is relieving convulsion, cooling blood for hemostasis, detoxicating functions;It is the succedaneum of Cornu rhinocerotis, because of it Composition is similar with Cornu rhinocerotis;It it is the panacea of removing heat from blood, hemostasis.Cure mainly calentura headache, high fever coma, spit blood, epistaxis, heat in blood, Sore throat pharyngeal swelling.
Cortex Phellodendri is bitter in the mouth, cold in nature, nontoxic.Return kidney, bladder warp.
Effect: there is the effects such as eliminating fire and detoxication, heat clearing and damp drying, nourishing kidney-yin, reducing the asthenic fever;Controlling diarrhea due to damp-heat, the deficiency of YIN is sent out Heat, jaundice, eczema etc..
After the present invention uses above-mentioned formula, prepared oral liquid, it is mainly used in acquired immune deficiency syndrome (AIDS) (AIDS), HIV (human immunodeficiency virus) (HIV) carrier recovers, improves, strengthens and improves immune function of human body, suppresses HIV (human immunodeficiency virus), improves T lymphocyte, the most carefully Born of the same parents, promotion macrophage phagocytic function.Improve the quality of living, extending life, prevent complication from occurring.Certainly, the present invention is used Formula can also make other regular dosage forms.
" in healthy energy is deposited, heresy can not do Huangdi's Internal Classics " is emphasized in traditional Chinese medical science immunity.Chinese medicine is referred to as all paathogenic factors " evil Gas ", human body itself is referred to as " healthy energy " to the defence capability of paathogenic factor.Positive QI-insufficiency or decline are the bases of human body morbidity.Disease Sick generation, change are under certain condition, the reflection of good and evil contradiction struggle.In the ordinary course of things, the healthy energy of human body is vigorous, evil Gas just be difficult to invade, though or have pathogen to attack, disease also will not occur.Only the weakest as human righteousness, it is insufficiently resistant to Exopathogen, pathogen is taken advantage of a weak point, and causes internal organs QI and blood functional disorder, disease just can occur.The positive deficiency of vital energy is not only pathogenetic of disease This reason, and advancing of disease, change, more after and lapse to, the contrast of good and evil both sides' strength to be depended on.As just won heresy Moving back, disease will take a favorable turn and fully recover;If vital QI cannot conquer pathogen, then sb.'s illness took a turn for the worse, rear bad.Thus the traditional Chinese medical science is in practice Consistent view strengthening body resistance and dispelling evil, is conceived to regulate the fuselage state of human body, strengthens resistance against diseases, transfers the overall defence of human body and makees With.While by the modern science means research traditional Chinese medical science, the Chinese herbal medicine of China is also carried out substantial amounts of research, from different perspectives Disclose they many effects, on the impact of biological immune also among inquiring into.Below with regard to part Chinese herbal medicine in formula with The result of study of immunologic function relation is disclosed directly below:
(1), the impact on leukocyte
1., promote that leukocyte count increases: Cordyceps, the Radix Astragali, Radix Codonopsis etc..
2., neutrophilic leukocyte phagocytic function is promoted: the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, the Rhizoma Anemarrhenae etc..
3., promote that mononuclear phagocyte number increases: Lentinus Edodes, Radix Glycyrrhizae etc..
4., macrophage phagocytic function is promoted: the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Codonopsis, the Cortex Eucommiae, Lentinus Edodes etc..
(2), the impact on T lymphocyte
1. promote that T lymphocyte number increases: Lentinus Edodes, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali etc..
2. lymphocyte transformation is promoted: Fructus Schisandrae Chinensis etc.
(3), the impact on humoral immunization
1., antibody tormation is promoted: Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Fructus Schisandrae Chinensis etc..
2., suppression antibody tormation: Radix Glycyrrhizae, Fructus Jujubae, Radix Angelicae Sinensis, Fructus Psoraleae etc..
(4), the impact on immunoglobulin: some Chinese herbal medicine, generation to immunoglobulin have facilitation.
1. IgA: the Radix Astragali, Radix Codonopsis etc..
2. IgE: the Radix Astragali.
3. IgG: Lentinus Edodes, the Radix Astragali etc..
4. IgM: Poria, the Radix Astragali etc..
(5), on suppression HIV (human immunodeficiency virus) impact:
Inhibiting HIV: Fructus Corni, Rhizoma Curcumae, Radix Glycyrrhizae etc..
Meanwhile, in formula, Cordyceps, Radix Codonopsis, Radix Rehmanniae Preparata, Fructus Corni, the Radix Astragali, Lentinus Edodes are principal agent;Adjust the kidney invigorating deficiency of YIN, sky All deficiency syndrome such as unit is not enough, recover impaired Tianyuan completely, fundamentally release Disease-causing gene;The Rhizoma Anemarrhenae, Cortex Phellodendri, Cornu Bubali, directly enter Liver, kidney, lung, stomach;With cold and cool nature and flavor it, heat-clearing toxin-expelling functions composition, across-the-board regulation partial heat, the disease of the deficiency of YIN excess of YANG, develop transconversion into heat All cards;Semen Ziziphi Spinosae, Poria cum Radix Pini, stir-baked RHIZOMA CORYDALIS with vinegar, Concha Ostreae, the Radix Paeoniae Alba, have taste cold, cool, flat, bitter, acid, directly enter liver, kidney, the heart, spleen;Sieve Select suppressing the hyperactive liver, mind tranquilizing and the heart calming, regulating qi to disperse stagnation pain relieving, nourishing the lung to arrest cough, heat-clearing toxin-expelling functions composition, prevent all mark diseases in advance.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail, but be not intended that the present invention any Limit.
A kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) of the present invention, this Chinese medicine composition is mainly by the Chinese medicine of following weight parts Raw material is made: Cordyceps 5-10 part, Radix Codonopsis 15-30 part, Radix Astragali 15-30 part, Lentinus Edodes 5-15 part, Rhizoma Curcumae 10-20 part, Radix Angelicae Sinensis 5- 15 parts, Rhizoma Atractylodis Macrocephalae 10-20 part, Arillus Longan 5-15 part, Fructus Corni 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part, Semen Ziziphi Spinosae (parched) 15-30 part, wheat Winter 10-18 part, Concha Ostreae 10-25 part, Radix et Rhizoma Rhei (stir-fried with wine) 10-20 part, Radix Rehmanniae Preparata 10-25 part and Semen Cuscutae 10-15 part.
It is further preferred that this Chinese medicine composition also includes the raw material of Chinese medicine of following weight parts: Cortex Eucommiae(processed with salt) 10-18 part, five Taste 10-20 part, Radix Paeoniae Alba 10-20 part, Rhizoma Pinelliae Preparata 5-15 part, Rhizoma Chuanxiong 10-18 part, Pericarpium Citri Reticulatae 5-13 part, Fructus Amomi 5-15 part and the Radix Aucklandiae 5-18 part.
It is further preferred that this Chinese medicine composition also includes the raw material of Chinese medicine of following weight parts: stir-baked RHIZOMA CORYDALIS with vinegar 10-25 part, sweet Grass 5-20 part, Poria cum Radix Pini's 10-18 part, Fructus Mume 5-15 part and Japanese raisintree fruit 10-18 part.
It is further preferred that this Chinese medicine composition also includes the raw material of Chinese medicine of following weight parts: Rhizoma Anemarrhenae 5-15 part, Cornu Bubali 10-20 part, Cortex Phellodendri 5-15 part.
As the case may be, can select to add the preferred raw material of Chinese medicine of above-mentioned any one or more combination.To carry The effect of high treatment.
The preparation method of a kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) of the present invention, the method comprises the steps:
(1) weigh the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine) by formulation weight part, after pulverizing in the water temperature of 60-80 DEG C water Carrying twice, medical material is 1:6-9 with the mass ratio of water, after twice gained extracting solution mixing, is incubated 4-5 hour, then at 50-70 DEG C temperature environment under, the volume ratio being concentrated in vacuo between water and extract is 1:1.3-2.2, obtains A concentrated solution;When in formula When increasing preferred raw material of Chinese medicine Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi, the Radix Aucklandiae, stir-baked RHIZOMA CORYDALIS with vinegar or Radix Glycyrrhizae, by above-mentioned raw material of Chinese medicine and the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni and Radix et Rhizoma Rhei (stir-fried with wine) water together carries and is concentrated in vacuo into A concentrated solution.
(2) weighing residue raw material of Chinese medicine by formulation weight part, after pulverizing, water carries twice, water temperature 80-100 DEG C, medical material and water Mass ratio be 1:4-8, after the mixing of twice gained extracting solution, stand 1-2 hour under room temperature, then the temperature of 50-70 DEG C Under environment, the volume ratio being concentrated in vacuo between water and extract is 1:1.5-2.0, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.1-with the volume ratio of B concentrated solution 1.5;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 1
Formula: Cordyceps 5 kilograms, Radix Codonopsis 15 kilograms, the Radix Astragali 15 kilograms, 5 kilograms of Lentinus Edodes, Rhizoma Curcumae 10 kilograms, Radix Angelicae Sinensis 5,000 Gram, the Rhizoma Atractylodis Macrocephalae 10 kilograms, Arillus Longan 5 kilograms, Fructus Corni 10 kilograms, Bulbus Fritillariae Thunbergii 10 kilograms, Semen Ziziphi Spinosae (parched) 15 kilograms, 10-Radix Ophiopogonis thousand Gram, Concha Ostreae 10 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 10 kilograms, 10 kilograms of Radix Rehmanniae Preparata and Semen Cuscutae 10 kilograms.
Preparation method: (1) weighs the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine) by formulation weight kilogram, at 60 DEG C after pulverizing In water temperature, water carries twice, and medical material is 1:6 with the mass ratio of water, after twice gained extracting solution mixing, is incubated 4 hours, then exists Under the temperature environment of 50 DEG C, the volume ratio being concentrated in vacuo between water and extract is 1:1.3, obtains A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight kilogram, after pulverizing, water carries twice, water temperature 80 DEG C, medical material and water Mass ratio is 1:4, after twice gained extracting solution mixing, stands 1 hour, then under the temperature environment of 50 DEG C, very under room temperature The volume ratio that sky is concentrated between water and extract is 1:1.5, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.1 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 2
Formula: Cordyceps 10 kilograms, Radix Codonopsis 30 kilograms, the Radix Astragali 30 kilograms, 15 kilograms of Lentinus Edodes, Rhizoma Curcumae 20 kilograms, Radix Angelicae Sinensis 15 kilograms, the Rhizoma Atractylodis Macrocephalae 20 kilograms, Arillus Longan 15 kilograms, Fructus Corni 20 kilograms, Bulbus Fritillariae Thunbergii 20 kilograms, Semen Ziziphi Spinosae (parched) 30 kilograms, Radix Ophiopogonis 18 kilograms, Concha Ostreae 25 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 20 kilograms, 25 kilograms of Radix Rehmanniae Preparata and Semen Cuscutae 15 kilograms.
Preparation method: (1) weighs the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine) by formulation weight kilogram, at 80 DEG C after pulverizing In water temperature, water carries twice, and medical material is 1:9 with the mass ratio of water, after twice gained extracting solution mixing, is incubated 5 hours, then exists Under the temperature environment of 70 DEG C, the volume ratio being concentrated in vacuo between water and extract is 1:2.2, obtains A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight kilogram, after pulverizing, water carries twice, water temperature 100 DEG C, medical material and water Mass ratio is 1:8, after twice gained extracting solution mixing, stands 2 hours, then under the temperature environment of 70 DEG C, very under room temperature The volume ratio that sky is concentrated between water and extract is 1:2.0, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.5 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 3
Formula: Cordyceps 6 kilograms, Radix Codonopsis 16 kilograms, the Radix Astragali 16 kilograms, 6 kilograms of Lentinus Edodes, Rhizoma Curcumae 12 kilograms, Radix Angelicae Sinensis 6,000 Gram, the Rhizoma Atractylodis Macrocephalae 12 kilograms, Arillus Longan 6 kilograms, Fructus Corni 12 kilograms, Bulbus Fritillariae Thunbergii 12 kilograms, Semen Ziziphi Spinosae (parched) 16 kilograms, Radix Ophiopogonis 12,000 Gram, Concha Ostreae 12 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 12 kilograms, 12 kilograms of Radix Rehmanniae Preparata, Semen Cuscutae 6 kilograms, Cortex Eucommiae(processed with salt) 10 kilograms, Fructus Schisandrae Chinensis 10 kilograms, The Radix Paeoniae Alba 10 kilograms, Rhizoma Pinelliae Preparata 5 kilograms, Rhizoma Chuanxiong 10 kilograms, Pericarpium Citri Reticulatae 5 kilograms, Fructus Amomi 5 kilograms and the Radix Aucklandiae 5 kilograms.
Preparation method: (1) weighs the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine), Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi by formulation weight kilogram And the Radix Aucklandiae, after pulverizing, in the water temperature of 60-65 DEG C, water carries twice, and medical material is 1:6.5 with the mass ratio of water, is extracted by twice gained After liquid mixing, it is incubated 4.5 hours, then under the temperature environment of 50-60 DEG C, the volume being concentrated in vacuo between water and extract Ratio is 1:1.5, obtains A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight kilogram, after pulverizing, water carries twice, water temperature 80-90 DEG C, medical material and water Mass ratio be 1:5, after the mixing of twice gained extracting solution, stand 1.5 hours under room temperature, then at the temperature ring of 50-60 DEG C Under border, the volume ratio being concentrated in vacuo between water and extract is 1:1.6, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.2 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 4
Formula: Cordyceps 9 kilograms, Radix Codonopsis 18 kilograms, the Radix Astragali 18 kilograms, 8 kilograms of Lentinus Edodes, Rhizoma Curcumae 15 kilograms, Radix Angelicae Sinensis 7,000 Gram, the Rhizoma Atractylodis Macrocephalae 15 kilograms, Arillus Longan 8 kilograms, Fructus Corni 15 kilograms, Bulbus Fritillariae Thunbergii 15 kilograms, Semen Ziziphi Spinosae (parched) 18 kilograms, Radix Ophiopogonis 13,000 Gram, Concha Ostreae 14 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 15 kilograms, 14 kilograms of Radix Rehmanniae Preparata, Semen Cuscutae 8 kilograms, Cortex Eucommiae(processed with salt) 18 kilograms, Fructus Schisandrae Chinensis 20 kilograms, The Radix Paeoniae Alba 20 kilograms, Rhizoma Pinelliae Preparata 15 kilograms, Rhizoma Chuanxiong 18 kilograms, Pericarpium Citri Reticulatae 13 kilograms, Fructus Amomi 15 kilograms and the Radix Aucklandiae 18 kilograms.
Preparation method: (1) weighs the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine), Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi by formulation weight kilogram And the Radix Aucklandiae, after pulverizing, in the water temperature of 70-75 DEG C, water carries twice, and medical material is 1:8 with the mass ratio of water, by twice gained extracting solution After mixing, being incubated 4 hours, then under the temperature environment of 65-70 DEG C, the volume ratio being concentrated in vacuo between water and extract is 1:2.0, obtains A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight kilogram, after pulverizing, water carries twice, water temperature 95-100 DEG C, medical material with The mass ratio of water is 1:6, after twice gained extracting solution mixing, stands 2 hours, then at the temperature ring of 65-70 DEG C under room temperature Under border, the volume ratio being concentrated in vacuo between water and extract is 1:2.0, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.3 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 5
Formula: Cordyceps 6 kilograms, Radix Codonopsis 20 kilograms, the Radix Astragali 20 kilograms, 10 kilograms of Lentinus Edodes, Rhizoma Curcumae 15 kilograms, Radix Angelicae Sinensis 8 Kilogram, the Rhizoma Atractylodis Macrocephalae 15 kilograms, Arillus Longan 10 kilograms, Fructus Corni 15 kilograms, Bulbus Fritillariae Thunbergii 15 kilograms, Semen Ziziphi Spinosae (parched) 20 kilograms, Radix Ophiopogonis 14 Kilogram, Concha Ostreae 15 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 15 kilograms, 15 kilograms of Radix Rehmanniae Preparata, Semen Cuscutae 10 kilograms, Cortex Eucommiae(processed with salt) 12 kilograms, Fructus Schisandrae Chinensis 12,000 Gram, the Radix Paeoniae Alba 12 kilograms, Rhizoma Pinelliae Preparata 6 kilograms, Rhizoma Chuanxiong 12 kilograms, Pericarpium Citri Reticulatae 6 kilograms, Fructus Amomi 6 kilograms, the Radix Aucklandiae 12 kilograms, stir-baked RHIZOMA CORYDALIS with vinegar 10 Kilogram, 5 kilograms of Radix Glycyrrhizae, Poria cum Radix Pini 10 kilograms, Fructus Mume 5 kilograms and Japanese raisintree fruit 10 kilograms.
Preparation method: (1) by formulation weight kilogram weigh the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine), Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi, The Radix Aucklandiae, stir-baked RHIZOMA CORYDALIS with vinegar and Radix Glycyrrhizae, after pulverizing, in the water temperature of 60-80 DEG C, water carries twice, and medical material is 1:6-9 with the mass ratio of water, will After twice gained extracting solution mixing, it is incubated 4-5 hour, then under the temperature environment of 50-70 DEG C, is concentrated in vacuo to water and extraction Volume ratio between thing is 1:1.3-2.2, obtains A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight kilogram, after pulverizing, water carries twice, water temperature 80-100 DEG C, medical material with The mass ratio of water is 1:4.5, after twice gained extracting solution mixing, stands 1-2 hour, then the temperature of 50-70 DEG C under room temperature Under degree environment, the volume ratio being concentrated in vacuo between water and extract is 1:1.7, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.35 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 6
Formula: Cordyceps 8 kilograms, Radix Codonopsis 22 kilograms, the Radix Astragali 22 kilograms, 12 kilograms of Lentinus Edodes, Rhizoma Curcumae 16 kilograms, Radix Angelicae Sinensis 9 Kilogram, the Rhizoma Atractylodis Macrocephalae 16 kilograms, Arillus Longan 12 kilograms, Fructus Corni 16 kilograms, Bulbus Fritillariae Thunbergii 16 kilograms, Semen Ziziphi Spinosae (parched) 22 kilograms, Radix Ophiopogonis 15 Kilogram, Concha Ostreae 16 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 16 kilograms, 16 kilograms of Radix Rehmanniae Preparata, Semen Cuscutae 12 kilograms, Cortex Eucommiae(processed with salt) 14 kilograms, Fructus Schisandrae Chinensis 14,000 Gram, the Radix Paeoniae Alba 14 kilograms, Rhizoma Pinelliae Preparata 8 kilograms, Rhizoma Chuanxiong 14 kilograms, Pericarpium Citri Reticulatae 7 kilograms, Fructus Amomi 8 kilograms, the Radix Aucklandiae 14 kilograms, stir-baked RHIZOMA CORYDALIS with vinegar 25 Kilogram, 20 kilograms of Radix Glycyrrhizae, Poria cum Radix Pini 18 kilograms, Fructus Mume 15 kilograms and Japanese raisintree fruit 18 kilograms.
Preparation method: (1) by formulation weight kilogram weigh the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine), Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi, The Radix Aucklandiae, stir-baked RHIZOMA CORYDALIS with vinegar and Radix Glycyrrhizae, after pulverizing, in the water temperature of 65-70 DEG C, water carries twice, and medical material is 1:8 with the mass ratio of water, by two After the mixing of secondary gained extracting solution, be incubated 5 hours, then under the temperature environment of 55-60 DEG C, be concentrated in vacuo to water and extract it Between volume ratio be 1:1.6, obtain A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight kilogram, after pulverizing, water carries twice, water temperature 85-90 DEG C, medical material and water Mass ratio be 1:6, after the mixing of twice gained extracting solution, stand 2 hours under room temperature, then the temperature environment of 55-60 DEG C Under, the volume ratio being concentrated in vacuo between water and extract is 1:2.0, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.4 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 7
Formula: Cordyceps 5 kilograms, Radix Codonopsis 24 kilograms, the Radix Astragali 24 kilograms, 9 kilograms of Lentinus Edodes, Rhizoma Curcumae 14 kilograms, Radix Angelicae Sinensis 10 Kilogram, the Rhizoma Atractylodis Macrocephalae 14 kilograms, Arillus Longan 9 kilograms, Fructus Corni 14 kilograms, Bulbus Fritillariae Thunbergii 14 kilograms, Semen Ziziphi Spinosae (parched) 24 kilograms, Radix Ophiopogonis 16,000 Gram, Concha Ostreae 18 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 14 kilograms, 18 kilograms of Radix Rehmanniae Preparata, Semen Cuscutae 9 kilograms, Cortex Eucommiae(processed with salt) 15 kilograms, Fructus Schisandrae Chinensis 16 kilograms, The Radix Paeoniae Alba 15 kilograms, Rhizoma Pinelliae Preparata 9 kilograms, Rhizoma Chuanxiong 15 kilograms, Pericarpium Citri Reticulatae 8 kilograms, Fructus Amomi 9 kilograms, the Radix Aucklandiae 15 kilograms, stir-baked RHIZOMA CORYDALIS with vinegar 15,000 Gram, 10 kilograms of Radix Glycyrrhizae, Poria cum Radix Pini 12 kilograms, Fructus Mume 6 kilograms, Japanese raisintree fruit 12 kilograms, the Rhizoma Anemarrhenae 5 kilograms, Cornu Bubali 10 kilograms and Cortex Phellodendri 5 Kilogram.
Preparation method: (1) by formulation weight kilogram weigh the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine), Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi, The Radix Aucklandiae, stir-baked RHIZOMA CORYDALIS with vinegar and Radix Glycyrrhizae, after pulverizing, in the water temperature of 70-75 DEG C, water carries twice, and medical material is 1:8 with the mass ratio of water, by two After the mixing of secondary gained extracting solution, be incubated 4 hours, then under the temperature environment of 65-70 DEG C, be concentrated in vacuo to water and extract it Between volume ratio be 1:2.1, obtain A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight kilogram, after pulverizing, water carries twice, water temperature 90-95 DEG C, medical material and water Mass ratio be 1:7, after the mixing of twice gained extracting solution, under room temperature, stand 1 hour, then under the temperature environment of 70 DEG C, The volume ratio being concentrated in vacuo between water and extract is 1:2.0, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.5 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 8
Formula: Cordyceps 7 kilograms, Radix Codonopsis 26 kilograms, the Radix Astragali 26 kilograms, 14 kilograms of Lentinus Edodes, Rhizoma Curcumae 18 kilograms, Radix Angelicae Sinensis 12 Kilogram, the Rhizoma Atractylodis Macrocephalae 18 kilograms, Arillus Longan 14 kilograms, Fructus Corni 18 kilograms, Bulbus Fritillariae Thunbergii 18 kilograms, Semen Ziziphi Spinosae (parched) 26 kilograms, Radix Ophiopogonis 17 Kilogram, Concha Ostreae 20 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 18 kilograms, 20 kilograms of Radix Rehmanniae Preparata, Semen Cuscutae 14 kilograms, Cortex Eucommiae(processed with salt) 16 kilograms, Fructus Schisandrae Chinensis 18,000 Gram, the Radix Paeoniae Alba 16 kilograms, Rhizoma Pinelliae Preparata 10 kilograms, Rhizoma Chuanxiong 16 kilograms, Pericarpium Citri Reticulatae 10 kilograms, Fructus Amomi 10 kilograms, the Radix Aucklandiae 16 kilograms, stir-baked RHIZOMA CORYDALIS with vinegar 20 kilograms, 15 kilograms of Radix Glycyrrhizae, Poria cum Radix Pini 15 kilograms, Fructus Mume 10 kilograms, Japanese raisintree fruit 14 kilograms, the Rhizoma Anemarrhenae 10 kilograms, Cornu Bubali 05 kilogram And Cortex Phellodendri 8 kilograms.
Preparation method: (1) by formulation weight kilogram weigh the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine), Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi, The Radix Aucklandiae, stir-baked RHIZOMA CORYDALIS with vinegar and Radix Glycyrrhizae, after pulverizing, in the water temperature of 80 DEG C, water carries twice, and medical material is 1:9 with the mass ratio of water, by twice institute After obtaining extracting solution mixing, it is incubated 5 hours, then under the temperature environment of 60-70 DEG C, is concentrated in vacuo between water and extract Volume ratio is 1:1.5, obtains A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight kilogram, after pulverizing, water carries twice, water temperature 100 DEG C, medical material and water Mass ratio is 1:8, after twice gained extracting solution mixing, stands 2 hours, then under the temperature environment of 70 DEG C, very under room temperature The volume ratio that sky is concentrated between water and extract is 1:1.9, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.5 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Embodiment 9
Formula: Cordyceps 10 kilograms, Radix Codonopsis 28 kilograms, the Radix Astragali 28 kilograms, 15 kilograms of Lentinus Edodes, Rhizoma Curcumae 20 kilograms, Radix Angelicae Sinensis 15 kilograms, the Rhizoma Atractylodis Macrocephalae 20 kilograms, Arillus Longan 15 kilograms, Fructus Corni 20 kilograms, Bulbus Fritillariae Thunbergii 20 kilograms, Semen Ziziphi Spinosae (parched) 28 kilograms, Radix Ophiopogonis 18 kilograms, Concha Ostreae 22 kilograms, Radix et Rhizoma Rhei (stir-fried with wine) 20 kilograms, 22 kilograms of Radix Rehmanniae Preparata, Semen Cuscutae 15 kilograms, Cortex Eucommiae(processed with salt) 18 kilograms, Fructus Schisandrae Chinensis 15 Kilogram, the Radix Paeoniae Alba 18 kilograms, Rhizoma Pinelliae Preparata 12 kilograms, Rhizoma Chuanxiong 18 kilograms, Pericarpium Citri Reticulatae 12 kilograms, Fructus Amomi 12 kilograms, the Radix Aucklandiae 18 kilograms, vinegar unit 22 kilograms recklessly, 18 kilograms of Radix Glycyrrhizae, Poria cum Radix Pini 16 kilograms, Fructus Mume 12 kilograms, Japanese raisintree fruit 16 kilograms, the Rhizoma Anemarrhenae 15 kilograms, Cornu Bubali 20,000 Gram and Cortex Phellodendri 15 kilograms.
Preparation method: (1) weighs the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine), Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi, wood by formulation weight part Perfume, stir-baked RHIZOMA CORYDALIS with vinegar and Radix Glycyrrhizae, after pulverizing, in the water temperature of 60-80 DEG C, water carries twice, and medical material is 1:8 with the mass ratio of water, by twice After the mixing of gained extracting solution, it is incubated 5 hours, then under the temperature environment of 70 DEG C, is concentrated in vacuo between water and extract Volume ratio is 1:2.2, obtains A concentrated solution;
(2) weighing residue raw material of Chinese medicine by formulation weight part, after pulverizing, water carries twice, water temperature 80 DEG C, medical material and the matter of water Amount ratio is 1:4, after twice gained extracting solution mixing, stands 1 hour under room temperature, then under the temperature environment of 50 DEG C, and vacuum The volume ratio being concentrated between water and extract is 1:1.5, obtains B concentrated solution;
(3) A concentrated solution mixing to obtain oral liquid with B concentrated solution, A concentrated solution is 1:1.5 with the volume ratio of B concentrated solution;
(4), after oral liquid is used conventional method packaging and sterilizing, finished product is made.
Clinical case 1
Wang Rui, man, 27 years old.Before using the oral liquid treatment of the present invention, can only lie on a bed, body constitution is become thin, unconsciousness, Being in comatose state, it is impossible to speech, hyperpyrexia continues two weeks, and temperature is up to four elevenths, from oral cavity to esophagus monilial infection, nothing Method is taken food, and feed or other liquid need to intubate and draw food.Urine need to plug in conduit, and face trunk, pustule, ulcer, infection occur in extremity Position antiseptic gauze is wrapped up, and owing to HIV (human immunodeficiency virus) the most well controls, virus replication is many, liver, splenomegaly, nervous system Pathological changes, peripheral neuritis encephalopathy, serious disease of the multiple harm bodies such as pulmonary infection occur.
Before the oral liquid treatment using the present invention, patient have employed multiple therapeutic scheme in hospital, uses various medicine, greatly The antibiotics of amount, two courses for the treatment of of antiviral agents, does not has any reaction through treatment, and to no effect, patient is in high heat, god to Drug therapy Intelligence is unclear, and the state of an illness is critical, hangs by a hair, and hospital is own determines abandoning cure.Clinical various data detect in hospital, and cd4 cell reduces, HIV+RNA level is high, and HIV (human immunodeficiency virus) replicates many, and prognosis is bad.
The oral liquid of the rear employing present invention, carries out patient improving immunity, antiviral therapy.
Clinical observation on the therapeutic effect: the 1st day, employing intubated and drained 100 milliliters, every 4 hours 1 time;2nd day, use intubated and drained 100 milliliters, every 4 hours 1 time, patient starts bowel movement, and along with body temperature is down to normally, the improvement of brain symptom is regained consciousness gradually.3rd My god, use suction pipe inhale take 100 milliliters, every 6 hours 1 time, patient is conscious, can speak, on inspection oral Candida by Fade mistake, and upper respiratory tract ulcer alleviates, and starts feed, inhales milk with suction pipe.4th day, take night and morning, each 100 millis Rising, the HIV (human immunodeficiency virus) of patient effectively controls, and the duplication of virus reduces, and widespread skin pustule, ulcer, gradually moves back, scabs, many Plant complications effectively to control, recover very fast.5th day, taking night and morning, each 100 milliliters, patient starts lower sick bed, OK Walk to compare with former clinotherapy and become quite a different person (inspection cd4 cell oneself recover normal range, immunocompetence different shaped lymphocyte Existing, various indexs all take a turn for the better).From the beginning of the 6th day, entering the after treatment phase, 2 months time, patient obtains comprehensive rehabilitation.
Clinical case 2
Name: Zhang Ji
Medical history: acquired immune deficiency syndrome (AIDS) is for many years
Health history: health is weak: the most out of breath, have a sleepless night, suffer from diarrhoea, whole body pruritus, anorexia.
Check before taking medicine: GT4:264,
Body weight before taking medicine: 69Kg.
Check after taking medicine: GT4:336,
Body weight after taking medicine: 72kg.
Administration time: 6 days
Instructions of taking: one day three times, early, middle and late each the most once.
Clinical manifestation: take the 3rd day and have headache sense and diarrhoea, disappear after having a headache one hour, but do not feel that health is tired Labor, belongs to drug reaction normal.Have no adverse reaction after 6th day, have a headache and suffer from diarrhea without, sleep is normal, and appetite increases, and walks Road is out of breath improvement.
Embodiment provided above is the better embodiment of the present invention, is only used for the convenient explanation present invention, not to this Bright make any pro forma restriction, any art has usually intellectual, if without departing from the carried skill of the present invention In the range of art feature, utilize the Equivalent embodiments that the done local of disclosed technology contents is changed or modified, and Without departing from the technical characteristic content of the present invention, all still fall within the range of the technology of the present invention feature.

Claims (9)

1. the Chinese medicine composition treating acquired immune deficiency syndrome (AIDS), it is characterised in that this Chinese medicine composition is mainly by following weight parts Medicine raw material is made: Cordyceps 5-10 part, Radix Codonopsis 15-30 part, Radix Astragali 15-30 part, Lentinus Edodes 5-15 part, Rhizoma Curcumae 10-20 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Arillus Longan 5-15 part, Fructus Corni 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part, Semen Ziziphi Spinosae (parched) 15-30 part, Radix Ophiopogonis 10-18 part, Concha Ostreae 10-25 part, Radix et Rhizoma Rhei (stir-fried with wine) 10-20 part, Radix Rehmanniae Preparata 10-25 part and Semen Cuscutae 10-15 part.
A kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) the most according to claim 1, it is characterised in that this Chinese medicine composition is also Raw material of Chinese medicine including following weight parts: Cortex Eucommiae(processed with salt) 10-18 part, Fructus Schisandrae Chinensis 10-20 part, Radix Paeoniae Alba 10-20 part, Rhizoma Pinelliae Preparata 5-15 Part, Rhizoma Chuanxiong 10-18 part, Pericarpium Citri Reticulatae 5-13 part, Fructus Amomi 5-15 part and Radix Aucklandiae 5-18 part.
A kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) the most according to claim 1, it is characterised in that this Chinese medicine composition is also Raw material of Chinese medicine including following weight parts: stir-baked RHIZOMA CORYDALIS with vinegar 10-25 part, Radix Glycyrrhizae 5-20 part, Poria cum Radix Pini's 10-18 part, Fructus Mume 5-15 part and trifoliate orange Sub-10-18 part.
A kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) the most according to claim 1, it is characterised in that this Chinese medicine composition is also Raw material of Chinese medicine including following weight parts: Rhizoma Anemarrhenae 5-15 part, Cornu Bubali 10-20 part, Cortex Phellodendri 5-15 part.
5. the method preparing the Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) described in any of the above-described claim, it is characterised in that should Method comprises the steps:
(1) weighing the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Fructus Corni, Radix et Rhizoma Rhei (stir-fried with wine) by formulation weight part, after pulverizing, in the water temperature of 60-80 DEG C, water carries two Secondary, medical material is 1:6-9 with the mass ratio of water, after twice gained extracting solution mixing, is incubated 4-5 hour, A is then concentrated in vacuo to obtain Concentrated solution;(2) weighing residue raw material of Chinese medicine by formulation weight part, after pulverizing, water carries twice, water temperature 80-100 DEG C, medical material and water Mass ratio is 1:4-8, after twice gained extracting solution mixing, stands 1-2 hour, B concentrated solution is concentrated in vacuo to obtain under room temperature;(3) A concentrated solution mixes to obtain oral liquid with B concentrated solution, and A concentrated solution is 1:1.1-1.5 with the volume ratio of B concentrated solution;(4) will be oral After liquid uses conventional method packaging and sterilizing, make finished product.
The method of the Chinese medicine composition of preparation treatment acquired immune deficiency syndrome (AIDS) the most according to claim 5, it is characterised in that when Chinese medicine is former When material also includes Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi and the Radix Aucklandiae, by Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, Fructus Amomi and the Radix Aucklandiae and the Chinese crude drug in step (1) Carry out water together to carry.
The method of the Chinese medicine composition of preparation treatment acquired immune deficiency syndrome (AIDS) the most according to claim 5, it is characterised in that when Chinese medicine is former When material also includes stir-baked RHIZOMA CORYDALIS with vinegar and Radix Glycyrrhizae, stir-baked RHIZOMA CORYDALIS with vinegar and Radix Glycyrrhizae are carried out water together with the Chinese crude drug in step (1) and carries.
8. the method treating the Chinese medicine composition of acquired immune deficiency syndrome (AIDS) according to the preparation described in claim 5 to 7 any claim, it is special Levy and be, in step (1), described in be concentrated in vacuo as, under the temperature environment of 50-70 DEG C, being concentrated in vacuo between water and extract Volume ratio be 1:1.3-2.2, obtain A concentrated solution.
9. the method treating the Chinese medicine composition of acquired immune deficiency syndrome (AIDS) according to the preparation described in claim 5 to 7 any claim, it is special Levy and be, in step (2), described in be concentrated in vacuo as, under the temperature environment of 50-70 DEG C, being concentrated in vacuo between water and extract Volume ratio be 1:1.5-2.0, obtain B concentrated solution.
CN201610730041.5A 2016-08-25 2016-08-25 A kind of Chinese medicine composition treating acquired immune deficiency syndrome (AIDS) and preparation method thereof Pending CN106177786A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105998143A (en) * 2016-07-29 2016-10-12 桂林淮安天然保健品开发有限公司 Anti-HIV pharmaceutical composition and preparation method thereof
CN106074891A (en) * 2016-07-29 2016-11-09 桂林淮安天然保健品开发有限公司 Pharmaceutical composition for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof
CN106138163A (en) * 2016-07-29 2016-11-23 桂林淮安天然保健品开发有限公司 A kind of pharmaceutical composition treating acquired immune deficiency syndrome (AIDS)
CN106138162A (en) * 2016-07-29 2016-11-23 桂林淮安天然保健品开发有限公司 The pharmaceutical composition for the treatment of acquired immune deficiency syndrome (AIDS)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105998143A (en) * 2016-07-29 2016-10-12 桂林淮安天然保健品开发有限公司 Anti-HIV pharmaceutical composition and preparation method thereof
CN106074891A (en) * 2016-07-29 2016-11-09 桂林淮安天然保健品开发有限公司 Pharmaceutical composition for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof
CN106138163A (en) * 2016-07-29 2016-11-23 桂林淮安天然保健品开发有限公司 A kind of pharmaceutical composition treating acquired immune deficiency syndrome (AIDS)
CN106138162A (en) * 2016-07-29 2016-11-23 桂林淮安天然保健品开发有限公司 The pharmaceutical composition for the treatment of acquired immune deficiency syndrome (AIDS)

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