CN102961525A - Medicine composition for losing weight and reducing blood lipid in auxiliary manner and oral liquid preparation method thereof - Google Patents

Abstract

The invention discloses a medicine composition for losing weight and reducing blood lipid in an auxiliary manner and an oral liquid preparation method thereof. The medicine composition comprises the following components in parts by weight: 20 parts of semen cassiae, 20 parts of hawthorns, 10 parts of ginkgo leaves, 10 parts of lotus leaves, 10 parts of fleeceflower root, 10 parts of oriental waterplantain rhizome, 10 parts of green tea leaves and 10 parts of L-carnitine. The medicine composition is a capsule with compound medicines as components, can expectedly achieve the function of supplementing nutrition, takes semen cassiae, hawthorns, ginkgo leaves, lotus leaves, fleeceflower root, oriental waterplantain rhizome, green tea leaves and L-carnitine as main raw materials, is processed by adopting a scientific and reasonable production process, has definite functions and controllable quality, is safe to take, has a simple preparation method and can be prepared by conventional equipment.

Description

A kind of pharmaceutical composition and oral liquor thereof for fat-reducing, auxiliary antilipemic

Technical field

The invention belongs to health product technology field, relate to a kind of healthcare dietetic liquid, particularly a kind of pharmaceutical composition and oral liquor thereof for fat-reducing, auxiliary antilipemic.

Background technology

The expection of developing drugs combination product reaches the health care of fat-reducing, auxiliary antilipemic.This product is with Semen Cassiae, Fructus Crataegi, Folium Ginkgo, and Folium Nelumbinis, Radix Polygoni Multiflori, Rhizoma Alismatis, green tea, VBT are primary raw material, and is theoretical according to Traditional Chinese health, adopts scientific and reasonable production technology to process, and this product function is clear and definite, and is quality controllable, takes safety.

Obesity refers to that obvious overweight and fat deposit to a certain degree is blocked up, is body fat, and especially triglyceride gathers a kind of state that too much causes.It does not refer to that simple body weight increases, but the superfluous state of body fat tissue savings.Obesity can increase the function of the danger of cardiovascular disease, the function that affects digestive system, hormonal system, danger, the obesity of increase Carciuogenesis not only affects pretty figure, and make troubles to life.Joint soft tissue injury, reproductive performance decline and mental maladjustment, heart disease, diabetes, atherosclerosis, fatty liver, cholelithiasis, edema, gout etc. are arranged in addition.Obesity or the major incentive of hyperlipidemia, and hyperlipidemia is the risk factor of apoplexy, coronary heart disease, myocardial infarction, sudden death.In addition, hyperlipidemia also is an important risk factor that promotes hypertension, impaired glucose tolerance, diabetes.Hyperlipidemia also can cause fatty liver, liver cirrhosis, cholelithiasis, pancreatitis, retinal hemorrhage, blind, peripheral vascular disease, limping, hyperuricemia.

The present invention is theoretical according to Traditional Chinese health, and with Semen Cassiae, Fructus Crataegi, Folium Ginkgo, Folium Nelumbinis, Radix Polygoni Multiflori, Rhizoma Alismatis, green tea, VBT are principal agent, eight kinds of composition synergism, reach the treatment functions such as clearing away liver fire and reducing fat, function of spleen and stomach regulating, antioxidation, take safety, can not produce dependency.

Summary of the invention

Purpose of the present invention aims to provide a kind of pharmaceutical composition and oral liquor thereof for fat-reducing, auxiliary antilipemic, this drug regimen is with Semen Cassiae, Fructus Crataegi, Folium Ginkgo, Folium Nelumbinis, Radix Polygoni Multiflori, Rhizoma Alismatis, green tea, VBT are principal agent, eight kinds of composition synergism reach the function of fat-reducing, auxiliary antilipemic.

Technical scheme of the present invention is: design a kind of pharmaceutical composition for fat-reducing, auxiliary antilipemic, it is characterized in that composition and weight proportion thereof that it contains are: 20 parts of Semen Cassiaes, 20 parts of Fructus Crataegis, 10 parts of Folium Ginkgos, 10 parts on Folium Nelumbinis, 10 parts of Radix Polygoni Multiflori, 10 parts of Rhizoma Alismatis, 10 parts of green teas, 10 parts of VBTs.

A kind of oral liquor of pharmaceutical composition for fat-reducing, auxiliary antilipemic is characterized in that it may further comprise the steps:

1) takes by weighing raw material by following weight ratio: 20 parts of Semen Cassiaes, 20 parts of Fructus Crataegis, 10 parts of Folium Ginkgos, 10 parts on Folium Nelumbinis, 10 parts of Radix Polygoni Multiflori, 10 parts of Rhizoma Alismatis, 10 parts of green teas, 10 parts of VBTs;

2) get the raw material of above-mentioned weight portion, except the VBT, add 8 times of water gagings and decoct 3 times, each one hour, filtrate was concentrated into that relative density is 1.28 ~ 1.30, temperature is 80 ℃ clear paste;

3) ethanol is added above-mentioned clear paste and make and contain scale and reach 70%, static, precipitate 48 hours, filter Recycled ethanol;

4) add 1% active carbon that accounts for gross weight, heated 30 minutes, filter;

5) VBT of the above-mentioned weight portion of adding, mixing; Add 1.5% stevioside that accounts for gross weight, taste masking;

6) adding distil water filters to total amount, packing, and sterilization gets final product.

Advantage of the present invention is, the Semen Cassiae bitter in the mouth in this prescription, sweet, salty, and cold nature enters liver, kidney, large intestine channel; Loosening bowel to relieve constipation, blood fat reducing makes eye bright, treatment constipation and hyperlipidemia, hypertension.Liver heat removing and eyesight improving, the diuretic relieving constipation has laxative action, reducing blood pressure and blood fat: the Fructus Crataegi slightly warm in nature, sour in the mouth is sweet, enters spleen, stomach, Liver Channel, and the function of promoting digestion and invigorating the stomach, activating blood circulation to dissipate blood stasis, convergence dysentery relieving is arranged.To the long-pending phlegm retention of meat, feeling of fullness acid regurgitation, dysentery hemorrhoidal hamorrhage, lumbago hernia, puerperal after-pains, lochiorrhea, children's's breast food stagnate etc., all effective in cure; Folium Ginkgo is sweet, bitter, puckery, and is flat.GUIXIN, lung meridian are astringed the lung, relieving asthma, and blood circulation promoting and blood stasis dispelling, pain relieving is used for cough and asthma due to lung deficiency; Coronary heart disease, angina pectoris, hyperlipidemia, anticoagulant is solid; The Folium Nelumbinis bitter in the mouth, property is flat, returns liver, spleen, stomach warp, and the function of clearing away summer-heat, the clear sun of hair growth promoting, cooling blood for hemostasis is arranged; Radix Polygoni Multiflori bitter in the mouth, sweet; Puckery, slightly warm in nature is returned liver, kidney channel.Mainly contain nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispel the wind, detoxify.Cure mainly soreness of the waist and knees, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula, hemorrhoid of blood deficiency Light-headedness, cardiopalmus, insomnia, the hepatic and renal YIN deficiency etc.; It is cold in nature for Rhizoma Alismatis, has the effect of promoting diuresis to eliminate damp pathogen.Modern medicine study, Rhizoma Alismatis can reduce serum total cholesterol and triacylglycerol content, slow down atherogenesis; Rhizoma Alismatis and preparation modern times thereof also are used for the treatment of auditory vertigo, dyslipidemia, seminal emission, fatty liver and diabetes etc.; Folium Camelliae sinensis contains and the closely-related biochemical of health really, Folium Camelliae sinensis not only have refresh oneself clear away heart-fire, clearing away summer-heat, eliminate indigestion and phlegm, go greasy fat-reducing, the relieving restlessness that clears away heart-fire, the pharmacological actions such as the relieving alcoholic intoxication that detoxifies, promoting the production of body fluid to quench thirst, pathogenic fire reducing make eye bright, dysentery relieving dehumidifying, also to modern disease, such as diseases such as Radiation sickness, cardiovascular and cerebrovascular disease, cancers, certain pharmacological effect is arranged; L-carnitine can not reduce moisture and muscle when reducing body fat, reducing body weight, regarded as the safest fat-reducing nutrient complementary goods that has no side effect in 2003 by international fat health tissues.This product is with Semen Cassiae, Fructus Crataegi, Folium Ginkgo, and Folium Nelumbinis, Radix Polygoni Multiflori, Rhizoma Alismatis, green tea, VBT are principal agent, and eight kinds of composition synergism reach the treatment functions such as clearing away liver fire and reducing fat, function of spleen and stomach regulating, kidney tonifying nourishing the liver.Use safety, convenient, no dependence.This prescription not only has fat-reducing, the effect of blood fat reducing, and other diseases also had auxiliary therapeutic action.

The specific embodiment

The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.

Embodiment 1

A kind of oral liquor of the pharmaceutical composition for fat-reducing, auxiliary antilipemic adopts following steps to make:

1) takes by weighing raw material by following weight ratio: 20 parts of Semen Cassiaes, 20 parts of Fructus Crataegis, 10 parts of Folium Ginkgos, 10 parts on Folium Nelumbinis, 10 parts of Radix Polygoni Multiflori, 10 parts of Rhizoma Alismatis, 10 parts of green teas, 10 parts of VBTs;

2) get the raw material of above-mentioned weight portion, except the VBT, add 8 times of water gagings and decoct 3 times, each one hour, filtrate was concentrated into that relative density is 1.28 ~ 1.30, temperature is 80 ℃ clear paste;

3) ethanol is added above-mentioned clear paste and make and contain scale and reach 70%, static, precipitate 48 hours, filter Recycled ethanol;

4) add 1% active carbon that accounts for gross weight, heated 30 minutes, filter;

5) VBT of the above-mentioned weight portion of adding, mixing; Add 1.5% stevioside that accounts for gross weight, taste masking;

6) adding distil water filters to total amount, packing, and sterilization gets final product.

The fat clinical observation of the embodiment of the invention 1 product treatment

1 data and method

1.1 physical data

Obese patient's 80 examples that selection is received treatment voluntarily are divided into each 20 example for the treatment of group and matched group at random, 12 for the treatment of group men, 8 of woman; Age between 28-60, average 44 years old; 11 of matched group men, 9 of woman; Each organizes patient age symptom formation without significant difference, and disease time is the longest 5 years, the shortest January.Has comparability (P〉0.05).

1.2 Therapeutic Method

The treatment group Primary Care is consistent, and matched group is not taken medicine.Treatment group 1 is used the embodiment of the invention, every day twice, 10ml.The green source of students diet tea in treatment group 2 Beijing Out Shure Health Care Products Co., Ltd, one time 1 bag, 1 time on the one.Treatment group 3 soup ministers are strong L-carnitine capsule doubly, every day 1 time, each 2.

2 results

2.1 curative effect determinate standard

Diagnostic criteria

World Health Organization (WHO) (WHO) regulation, BMI is normal at 18.5～24.9 kg/ m2, and 25～29.9kg/ m2 is overweight, and 〉=30 kg/ m2 are fat.

Criterion is:

Recovery from illness: weight loss reaches in standard body weight or the overweight scope;

Produce effects: weight loss＞5kg;

Take a turn for the better: weight loss＞3kg;

Invalid: weight loss is less than 3kg.

2.2 therapeutic outcome

?	Cure	Produce effects	Take a turn for the better	Invalid	Effective percentage
						Matched group	0	0	0	20	0
Treatment group 1	9	6	4	1	95%
						Treatment group 2	7	7	4	2	90%
Treatment group 3	6	8	3	3	85%

3 discuss

The traditional Chinese medical science is thought fat and is caused that by following reason one is natural endowment, i.e. inherited genetic factors; Two for having a liking for food delicious food savoury, and namely diet surpasses the human body requirements amount; Three is that lying on bed for a long time is moving less, and physical consumption is obviously reduced, and causes overnutrition, fat is filled cause fat fat in muscle; Four visceral dysfunctions, deficiency of spleen-QI or the hepatic and renal YIN deficiency, accumulatively wet raise phlegm is turbid and cause fat fat.Adopt the present invention's combination theoretical according to Traditional Chinese health, the treatment such as comprehensively regulating, fat-reducing liver-protecting, function of spleen and stomach regulating, kidney tonifying nourishing the liver function.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.

Claims (2)

1. pharmaceutical composition that is used for fat-reducing, auxiliary antilipemic, it is characterized in that material composition and weight proportion thereof that it contains are: 20 parts of Semen Cassiaes, 20 parts of Fructus Crataegis, 10 parts of Folium Ginkgos, 10 parts on Folium Nelumbinis, 10 parts of Radix Polygoni Multiflori, 10 parts of Rhizoma Alismatis, 10 parts of green teas, 10 parts of VBTs.

2. described a kind of oral liquor of pharmaceutical composition for fat-reducing, auxiliary antilipemic according to claim 1 is characterized in that it may further comprise the steps:

1) takes by weighing raw material by following weight ratio: 20 parts of Semen Cassiaes, 20 parts of Fructus Crataegis, 10 parts of Folium Ginkgos, 10 parts on Folium Nelumbinis, 10 parts of Radix Polygoni Multiflori, 10 parts of Rhizoma Alismatis, 10 parts of green teas, 10 parts of VBTs;

2) get the raw material of above-mentioned weight portion, except the VBT, add 8 times of water gagings and decoct 3 times, each one hour, filtrate was concentrated into that relative density is 1.28 ~ 1.30, temperature is 80 ℃ clear paste;

3) ethanol is added above-mentioned clear paste and make and contain scale and reach 70%, static, precipitate 48 hours, filter Recycled ethanol;

4) add 1% active carbon that accounts for gross weight, heated 30 minutes, filter;

5) VBT of the above-mentioned weight portion of adding, mixing; Add 1.5% stevioside that accounts for gross weight, taste masking;

6) adding distil water filters to total amount, packing, and sterilization gets final product.