CN102526537A - Medicinal composition for treating hyperglycemia - Google Patents

Abstract

The invention discloses a medicinal composition for treating hyperglycemia. In order to solve the problems of adverse reaction caused by the long-term administration of the conventional western medicines for treating hyperglycemia and non-obvious curative effect of Chinese medicines, the invention provides a medicinal composition which does not have toxic or side effect, is safe in administration, can be taken for a long time, has an obvious treatment effect and is used for treating hyperglycemia. The medicinal composition is prepared by the compatibility of the following Chinese medicinal raw materials: kudzuvine root, lotus leaf, white chrysanthemum root, corn stigma, cassia seed, fragrant solomonseal rhizome, small-leaved dasiphora leaf and flower, loquat leaf, mulberry, cassia bark, hawthorn fruit, Chinese angelica, oriental waterplantain rhizome, water chestnut, ginkgo seed, lotus plumule, lily, rose, ginkgo seed leaf, Chinese rose flower, taro flower, silk tree flower, moutan flower, ophiopogon, fig, virgate wormwood, mung bean, wheat bran, lycium bark, siberian solomonseal rhizome, ginseng and prepared rehmannia root.

Description

A kind of pharmaceutical composition of treating hyperglycemia

Technical field

The present invention relates to the field of Chinese medicines, specifically a kind of pharmaceutical composition of treating hyperglycemia.

Background technology

Coronary heart disease, apoplexy, diabetes spp are the highest in global sickness rate, and mortality rate is the highest, and disability rate is the highest, and relapse rate is the highest, the three big chronic diseases that long-term slight illness is burdened with, and this three big chronic disease and hyperglycemia all have direct or indirect relation.Therefore blood sugar regulation makes it return to normal level, is to prevent arteriosclerosis, prevents one of important measures of three big chronic diseases.

Because improving constantly of living standard; The sickness rate of hyperglycemia has and increases gradually and the middle-aged population Development Trend, and therefore, hyperglycemia has become one of focus of metabolic disease research in recent ten years; And obtained certain progress; Formed the multiple Western medicine that blood fat reducing, blood sugar reducing function are arranged, but prolonged application there is untoward reaction more.In recent years; Chinese medicine prevents that the research of hyperglycemia from being paid attention to deeply; Though have the Chinese traditional patent formulation preparation of some blood sugar lowering to form at present, be used for the blood stasis retardance and can play the upward few of effect, and curative effect be average; Particularly high density lipoprotein increasing, reduce low density lipoprotein, LDL, triglyceride, cholesterol etc. comprehensive aspect, not seeing as yet at present has Chinese patent medicine to reach.

Summary of the invention

The objective of the invention is to overcome untoward reaction, the unconspicuous problem of Chinese medicine curative effect that existing Western medicine prolonged application of treating hyperglycemia is brought; Have no side effect and provide a kind of; Drug safety can be taken for a long time, and the significant a kind of pharmaceutical composition of treating hyperglycemia of therapeutic effect.

Another object of the present invention provides the method for preparing of this medicine.

A kind of pharmaceutical composition of treating hyperglycemia of the present invention is that the raw material of Chinese medicine compatibility by following weight parts forms:

Radix Puerariae 8-20 part; Folium Nelumbinis 8-20 part; Radix Paeoniae Alba 8-20 part; Stigma Maydis 8-20 part; Semen Cassiae 8-20 part; Rhizoma Polygonati Odorati 8-20 part; Folium set Flos potentillae parvifoliae 8-20 part; Folium Eriobotryae 8-20 part; Fructus Mori 5-15 part; Cortex Cinnamomi 5-15 part; Fructus Crataegi 5-15 part; Radix Angelicae Sinensis 5-15 part; Rhizoma Alismatis 5-15 part; Corm Eleocharitis 5-15 part; Semen Ginkgo 5-15 part; Plumula Nelumbinis 5-15 part; Flos Lilii viriduli 3-10 part; Flos Rosae Rugosae 3-10 part; Folium Ginkgo 3-10 part; Flos Rosae Chinensis 3-10 part; Flos Colocasiae Esculentae 3-10 part; Flos Albiziae 3-10 part; Flos Moutan 3-10 part; Radix Ophiopogonis 3-10 part; Fructus Fici 2-8 part; Herba Artemisiae Scopariae 2-8 part; Semen phaseoli radiati 2-8 part; Testa Tritici 2-8 part; Cortex Lycii 2-8 part; Rhizoma Polygonati 2-8 part; Radix Ginseng 2-8 part; Radix Rehmanniae Preparata 2-8 part;

Method for preparing:

1) by formula proportion with Radix Puerariae, Radix Paeoniae Alba, Semen Cassiae, Radix Angelicae Sinensis, Testa Tritici, that Rhizoma Polygonati is ground into fine powder is subsequent use;

2) according to formula proportion will remain Chinese herbal medicine clean → screening put into the marmite big fire boil change after 20 minutes slow fire boil 40 minutes → extract supernatant to be cooled to room temperature → filtrate for later use; Slag is added water → decoction again pour into after boil subsequent usely, twice filtrating is mixed until being boiled into the thick paste shape, and it is subsequent use to be cooled to room temperature after bake dry grinding to 300-400 order fine powder;

3) incapsulate after by formula proportion and place the disinfecting container of high temperature >=100 ℃ to carry out disinfection, get product twice subsequent use fine powder mix homogeneously.

Instructions of taking: take with warm water half an hour ante cibum, takes 15g every day three times at every turn, warm water delivery service, one month one course of treatment.The avoid cold and uncooked food thing of pungent stimulation.

A kind of pharmaceutical composition of treating hyperglycemia of the present invention is that the raw material of Chinese medicine compatibility by following weight parts forms:

Radix Puerariae 10-18 part; Folium Nelumbinis 10-18 part; Radix Paeoniae Alba 10-18 part; Stigma Maydis 10-18 part; Semen Cassiae 10-18 part; Rhizoma Polygonati Odorati 10-18 part; Folium set Flos potentillae parvifoliae 10-18 part; Folium Eriobotryae 10-18 part; Fructus Mori 6-14 part; Cortex Cinnamomi 6-14 part; Fructus Crataegi 6-14 part; Radix Angelicae Sinensis 6-14 part; Rhizoma Alismatis 6-14 part; Corm Eleocharitis 6-14 part; Semen Ginkgo 6-14 part; Plumula Nelumbinis 6-14 part; Flos Lilii viriduli 4-9 part; Flos Rosae Rugosae 4-9 part; Folium Ginkgo 4-9 part; Flos Rosae Chinensis 4-9 part; Flos Colocasiae Esculentae 4-9 part; Flos Albiziae 4-9 part; Flos Moutan 4-9 part; Radix Ophiopogonis 4-9 part; Fructus Fici 3-7 part; Herba Artemisiae Scopariae 3-7 part; Semen phaseoli radiati 3-7 part; Testa Tritici 3-7 part; Cortex Lycii 3-7 part; Rhizoma Polygonati 3-7 part; Radix Ginseng 3-7 part; Radix Rehmanniae Preparata 3-7 part;

A kind of pharmaceutical composition of treating hyperglycemia of the present invention is that the raw material of Chinese medicine compatibility by following weight parts forms:

15 parts of Radix Puerariaes; 15 parts on Folium Nelumbinis; 15 parts of Radix Paeoniae Albas; 15 parts of Stigma Maydis; 15 parts of Semen Cassiaes; 15 parts of Rhizoma Polygonati Odorati; 15 parts of Folium set Flos potentillae parvifoliae; 15 parts of Folium Eriobotryaes; 12 parts in Fructus Mori; 12 parts of Cortex Cinnamomis; 12 parts of Fructus Crataegis; 12 parts of Radix Angelicae Sinensis; 12 parts of Rhizoma Alismatis; 12 parts of Corm Eleocharitiss; 12 parts of Semen Ginkgoes; 12 parts of Plumula Nelumbiniss; 8 parts of Flos Lilii viridulies; 8 parts of Flos Rosae Rugosaes; 8 parts of Folium Ginkgos; 8 parts of Flos Rosae Chinensiss; 8 parts of Flos Colocasiae Esculentaes; 8 parts of Flos Albiziaes; 8 parts of Flos Moutaies; 8 parts of Radix Ophiopogonis; 5 parts of Fructus Ficis; 5 parts of Herba Artemisiae Scopariae; 5 parts in Semen phaseoli radiati; 5 parts of Testa Triticis; 5 parts of Cortex Lycii; 5 parts of Rhizoma Polygonatis; 5 parts of Radix Ginsengs; 5 parts of Radix Rehmanniae Preparata;

The property of medicine and the pharmacology of Chinese herbal medicine that the present invention selects for use are respectively:

Radix Puerariae:

[meridian distribution of property and flavor] is cool in nature, sweet in the mouth, suffering.

[function cures mainly] induced sweat and brought down a fever, and promotes the production of body fluid rash, yang invigorating antidiarrheal.Be used for fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels.

Folium Nelumbinis:

[nature and flavor] bitterness, flat.1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " slightly warm in nature is flat, acrid in the mouth." 2. " book on Chinese herbal medicine is high former ": " abnormal smells from the patient is bitter, flat, nontoxic." 3. " the medical center bun is wanted ": " bitterness, flat, little salty." go into the heart, liver, spleen channel.1. " book on Chinese herbal medicine is looked for the truth ": " go into gallbladder." 2. " book on Chinese herbal medicine is new again ": " gone into the heart, liver, lung three warps." 3. " book on Chinese herbal medicine brief points ": " are gone into lunar, the Yangming Channel of foot."?　　

[function cures mainly] clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.Be used for the summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood is told nosebleed, the metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding.Be used for multiple hemorrhage and puerperal blood faints.

Radix Paeoniae Alba:

[meridian distribution of property and flavor] hardship, cold.Go into the heart, lung two warps.

[effect cures mainly] heat-clearing and toxic substances removing, it is swollen to control furuncle, abscess of the throat, membranous pharyngitis.

Stigma Maydis:

[nature and flavor] property is flat, and slightly sweet flavor is nontoxic.

[function cures mainly] diuresis expels the heat-evil, suppressing the hyperactive liver, function of gallbladder promoting.Control oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, cholelithiasis, diabetes, hematemesis and epistaxis, nasal sinusitis, acute mastitis.

Semen Cassiae:

[nature and flavor] mildly bitter flavor is little sweet, and property is flat, little cold.

[function] returned liver, kidney, large intestine channel.Liver heat removing makes eye bright, relieving constipation.It is dizzy to be used to have a headache, and conjunctival congestion is dim-sighted, constipation.1: the effect that brings high blood pressure down; 2: the effect of resisting pathogenic microbes; 3: reduce the effect of serum cholesterol and triglyceride; 4: the diarrhea effect; 5: to uterine contraction and the effect of hastening parturition.

Rhizoma Polygonati Odorati:

[meridian distribution of property and flavor] is sweet, is slightly cold, and attaches to the lung and stomach meridians.

[function cures mainly] nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst is used for the lung stomach-Yin and hinders, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.

Folium set Flos potentillae parvifoliae:

[meridian distribution of property and flavor] is sweet; Cold. kidney; Urinary bladder channel.

[curing mainly] disturbance of lower legs due to pathogenic cold and dampness; Prurigo; Mastitis.

[effect] dampness removing; Antipruritic; Detoxifcation.

Folium Eriobotryae:

[meridian distribution of property and flavor] hardship is slightly cold.Attach to the lung and stomach meridians.

[function cures mainly] clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.Be used for the cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, the gastric heat vomiting, dysphoria with smothery sensation is thirsty.

Fructus Mori:

[nature and flavor] are sweet, are slightly cold; GUIXIN, liver, kidney channel.

[function cures mainly] treating the liver kidney yin is lost, and send and take off, constipation, order is dark, tinnitus, former infections, articular instability.It has the skin of improvement (comprising scalp) blood supply, the nutrition skin, makes effect such as the delicate and black hair of skin, and can slow down aging.Fructus Mori is be healthy and strong U.S. face, antidotal good fruit and a good medicine of middle-aged and elderly people.Normal food Fructus Mori can make eye bright, the tired dry and astringent symptom of easing eyes.Fructus Mori has immunologic enhancement.Fructus Mori has effect of gain to spleen, and reaction has potentiation to hemolytic, can prevent human body artery sclerosis, skeleton arthrosclerosis, enhances metabolism; Fructus Mori can promote the growth of erythrocyte, prevents leukopenia, and diseases such as treatment diabetes, anemia, hypertension, hyperlipidemia, coronary heart disease, neurasthenia are had auxiliary curative effect.Fructus Mori has effects such as promoting the production of body fluid to quench thirst, facilitating digestion, help defecation, and proper amount of edible can promote gastric secretion, stimulates enterokinesia and removes scorching.The traditional Chinese medical science thinks that Fructus Mori is sweet in flavor and cold in property, has the liver and the kidney tonifying, an effect such as the intestine moistening of promoting the production of body fluid, black hair make eye bright.

Cortex Cinnamomi:

[nature and flavor] extremely hot in nature, acrid in the mouth, sweet.

It is supporing yang that [function cures mainly] mended fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Be used for sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, amenorrhea, dysmenorrhea, warming the meridian and promoting blood circulation.

Fructus Crataegi:

[nature and flavor] sour in the mouth, sweet, slightly warm in nature.

[function cures mainly] appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm.Be used for carnivorous stagnate long-pending, lump in the abdomen, abdominal distention feeling of fullness, the stasis of blood resistance stomachache, phlegm retention, have loose bowels, discharging fresh blood stool etc.

Radix Angelicae Sinensis:

[nature and flavor] are warm in nature, hide sweet, hot.

[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.

Rhizoma Alismatis:

[meridian distribution of property and flavor] is sweet, and be cold; Return kidney, urinary bladder channel.

[function cures mainly] diuresis, clearing away damp-heat; Be used for dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.

Corm Eleocharitis:

[meridian distribution of property and flavor] bulb: sweet, cold;

[function cures mainly] bulb: relieve heat and thirst, dampness removing reduces phlegm, blood pressure lowering.Be used for the consumption of body fluid caused by febrile disease excessive thirst, laryngopharynx swelling and pain, stomatitis, jaundice due to damp-heat, hypertension, dysuria, measles, cough due to lung-heat, pneumosilicosis, bleeding hemorrhoids.The Corm Eleocharitis mouthfeel is sweet crisp, and is nutritious, contains protein, fat, crude fibre, carotene, vitamin B, vitamin C, ferrum, calcium, phosphorus and carbohydrate.Can eat something rare, also can be used for cooking, can make starch, also can make Chinese medicine.

Semen Ginkgo:

[nature and flavor] are sweet; Bitter; Puckery; Property is put down; Mild toxicity.

[return through] lung meridian; Kidney channel.

[function] astringing lung QI for relieving asthma; The leukorrhagia stopping reducing urination.

[curing mainly] asthma phlegmatic cough; Leucorrhea; Nebulousurine; Seminal emission; Frequent micturition; Innominate toxic swelling; The Zha nose; The tinea skin ulcer.

Plumula Nelumbinis:

[nature and flavor] hardship, cold, nontoxic;

[effect] clears away heart-fire, and reduces phlegm and internal heat hemostasis, arresting seminal emission.Control vexedly, thirsty, spit blood seminal emission, conjunctival congestion and swelling pain." book on Chinese herbal medicine is new again ": clearing away heart-fire, the suppressing the hyperactive liver fire, lung-fire falls in the purgation of spleen excess fire.The relieving restlessness of relieving summer heat, promoting the production of body fluid to quench thirst is controlled the order redness.

Flos Lilii viriduli:

[nature and flavor] Bulbus Lilii sweet in the mouth, cold nature; GUIXIN, lung meridian.

[function cures mainly] nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Be used for deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep, absentminded.Have nourishing YIN and moistening the lung cough-relieving effect, be used for the cough caused by dryness-heat of deficiency of lung-YIN, sputum mixed with blood is like all sorts of flowers cream.Control chronic cough of deficiency lung, the chronic cough spitting of blood is like baihe gujin decoction.Have the clearing away heart-fire for tranquillization effect, it is unclear to be used for the calentura waste heat, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep etc.

Flos Rosae Rugosae:

[meridian distribution of property and flavor] sweet, little hardship, temperature.Return liver, spleen channel.　　

[function cures mainly] promoting QI circulation for relieving depression, and blood, pain relieving.Be used for stomachache due to hyperactive liver-QI attacking the stomach, the lack of appetite vomiting and nausea, menoxenia is fallen and is pounced on the pain of injury.

Folium Ginkgo:

[meridian distribution of property and flavor] bitter in the mouth, puckery is flat; The benefit heart is astringed the lung removing dampness antidiarrheal.

[function cures mainly] is uncomfortable in chest pained, severe palpitation, phlegm dyspnea cough, dysentery, leucorrhea.

Flos Rosae Chinensis:

[meridian distribution of property and flavor] sweet in the mouth, warm in nature is gone into Liver Channel.

[function cures mainly] has the effect of promoting blood flow to regulate menstruation, subduing swelling and detoxicating.Because blood stasis dispelling, circulation of qi promoting, the analgesic effect of Flos Rosae Chinensis are obvious; So often be used to treat diseases such as menoxenia, dysmenorrhea; Amenorrhea appears in the women or menstruation is thin, color is light and the amount less, lower abdominal pain; It is smooth with constipation due to dry stool etc. to have spirit concurrently, or above-mentioned symptom occurs in menstrual phase, good with victory spring soup therapeutic effect.

Flos Colocasiae Esculentae:

[nature and flavor] " Sichuan Chinese medicinal herbal ": property is flat, and the flavor fiber crops are poisonous.

[function cures mainly] treats for stomachache, and spits blood uterine prolapse, hemorrhoid, proctoptosis.

Flos Albiziae:

The effect of allaying excitement mainly is to control effects such as pent-up is uncomfortable in chest, insomnia forgetfulness, nourishing YIN and invigorating YANG, ophthalmic, neurasthenia.Shu Yu regulates the flow of vital energy, and calms the nerves, and is active.It is uncomfortable in chest to control pent-up, and insomnia is forgetful, wind-fire ophthalmic, blurring of vision, pharyngalgia, carbuncle, traumatic injury pain.

Flos Moutan:

Paeonia suffruticosa not only has ornamental value, but also has very high medical value.The root of Paeonia suffruticosa is processed into " Cortex Moutan ", is famous and precious Chinese herbal medicine.Its cold nature, acrid in the mouth, nontoxic, go into the heart, liver, kidney three warps, dissipating blood stasis blood is arranged, purify the blood and blood, pain relieving, the effect of stimulating the menstrual flow, bring high blood pressure down in addition, the effect of anti-inflammation, clothes can be lengthened the life by beneficial body for a long time.The regulating liver-QI that nourishes blood, is applicable to chloasma faciei at the strongly fragrant blood stasis dispelling that looses, and skin aging is often drunk the QI and blood lung of living, and appearance is ruddy, improves menoxenia, and dysmenorrhea is ended sweating due to debility, night sweat.

Radix Ophiopogonis:

[meridian distribution of property and flavor] sweet, little hardship is slightly cold; GUIXIN, lung, stomach warp.

[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Be used for dryness of the lung dry cough, the chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.

Fructus Fici:

[nature and flavor] sweet in the mouth, flat;

[function] nourishing the lung to arrest cough, clearing away heat and moistening the bowels: be used for cough with asthma, laryngopharynx swelling and pain, constipation, hemorrhoid.

Herba Artemisiae Scopariae:

[Nature and flavor ]Toil, cold.

1. " herbal classic ": " bitter in the mouth is flat."

2. " not Lu ": " be slightly cold, nontoxic."

3. " property of medicine opinion ": " bitter in the mouth is hot, and is slightly poisonous."

4. " pearl sac ": " bitter sweet."

[Gui Jing ]Go into liver, spleen, urinary bladder channel.

1. Zhang Yuansu: " go into meridian of Foot-TAI YANG."

2. " Bencao Jingshu ": " bright, lunar, the sun three warps of foot sun."

3. " book on Chinese herbal medicine is new again ": " go into liver, kidney two warps."

[function cures mainly] clearing away heat-damp and promoting diuresis.Control jaundice due to damp-heat, dysuria, pruritus due to wind pathogen skin ulcer scabies.Join Fructus Gardeniae, Radix Et Rhizoma Rhei is controlled YANG jaundice; Join Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis is controlled YIN jaundice.

Semen phaseoli radiati:

Semen phaseoli radiati has purposes such as grain, vegetable, green manure and medicine.It is traditional bean food of Chinese people.The content of Semen phaseoli radiati albumen matter almost is 3 times of Semen oryzae sativae, and inorganic salts such as multivitamin, calcium, phosphorus, ferrum are all many than Semen oryzae sativae.Therefore, it not only has good edibility, also has extraordinary medical value, and saying of " the food paddy of benefiting mankind " arranged.In hot summer, sweet mung bean soup is the favorite beverage for relieving summer heat of common people especially.Effect: the sweet cold of Semen phaseoli radiati nature and flavor has the merit of heat-clearing and toxic substances removing.Summer, the people in hot environment work perspired many; Water liquid loss is very big, and intravital electrolyte balance is destroyed, and boiling with Semen phaseoli radiati that soup replenishes is optimal method; Can clearing away summer-heat and supplementing QI, the diuresis of quenching the thirst; Can not only keep the skin wet, and can also in time replenish inorganic salt, significance arranged keeping the electrolyte balance of water liquid.Congee with mung beans also has similar effect.Semen phaseoli radiati also has Detoxication.As meet machine phosphorus insecticide poisoning, lead poisoning, alcoholism (drunk) or eat situation such as wrong medicine; Before hospital rescues, can irritate next bowl sweet mung bean soup earlier and carry out emergent management; Through the people who is everlasting and works under the poisonous environment or contact noxious substance, often edible mung bean comes detoxication health care.Often edible mung bean can supplement the nutrients physical strength reinforcing.

Testa Tritici:

[nature and flavor] are sweet, and are cold, nontoxic;

[function cures mainly] controlled sweating due to debility, and night sweat is let out profit, diabetes, and stomatitis, herpes simplex, folding is hindered, rheumatic arthralgia, beriberi.1. supplement to the Herbal: " dough-making powder is made cake, and stopping leak is sharp, reduces phlegm and internal heat in the accent, strong people.Mix steaming with vinegar, bag is contained, and presses waist feet wound folding place, pain-relieving powder for treating blood." 2. " Japan hanako materia medica ": " disease herpes simplex when controlling, sore due to scald and burn is mashed, pounces on the damage folding, and blood stasis, vinegar are fried and are pasted basement." 3. " detailed outline ": " steaming with vinegar is pressed brothers' rheumatic arthralgia, the disturbance of lower legs due to pathogenic cold and dampness, and reciprocity is to sweating.The end clothes end sweating due to debility."

Cortex Lycii:

[nature and flavor] sweet in the mouth, cold;

[function cures mainly] heat clearing away, removing heat from blood; Asthenia hectic fever night sweat, the lung-heat cough with asthma is spitted blood, epistaxis, stranguria with blood is quenched one's thirst, hypertension, carbuncle, malignant boil.

Rhizoma Polygonati:

[nature and flavor] are sweet, and are flat; Return lung, spleen, kidney channel.

[function cures mainly] nourishing kidney profit spleen, invigorating the spleen and replenishing QI.Deficiency of YIN chronic cough; The xeropulmonary cough; Insufficiency of the spleen weak; The lack of appetite xerostomia; Quench one's thirst; The deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; The tinnitus order is dark; Early whitening of beard and hair; The empty win of body is thin; Wind favus disease.

Radix Ginseng:

[nature and flavor] sweet, little hardship, flat; Return spleen, lung, heart channel.

[function cures mainly] strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid, and calms the nerves.Be used for weak body and prostration, the cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.

Radix Rehmanniae Preparata:

[meridian distribution of property and flavor] sweet, tepor; Return liver, kidney channel.

[function cures mainly] nourishing YIN and supplementing blood, beneficial essence is filled out marrow.Be used for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.

The specific embodiment

Embodiment 1, prescription:

Radix Puerariae 8g; Folium Nelumbinis 8g; Radix Paeoniae Alba 8g; Stigma Maydis 8g; Semen Cassiae 8g; Rhizoma Polygonati Odorati 8g; Folium set Flos potentillae parvifoliae 8g; Folium Eriobotryae 8g; Fructus Mori 5g; Cortex Cinnamomi 5g; Fructus Crataegi 5g; Radix Angelicae Sinensis 5g; Rhizoma Alismatis 5g; Corm Eleocharitis 5g; Semen Ginkgo 5g; Plumula Nelumbinis 5g; Flos Lilii viriduli 3g; Flos Rosae Rugosae 3g; Folium Ginkgo 3g; Flos Rosae Chinensis 3g; Flos Colocasiae Esculentae 3g; Flos Albiziae 3g; Flos Moutan 3g; Radix Ophiopogonis 3g; Fructus Fici 2g; Herba Artemisiae Scopariae 2g; Semen phaseoli radiati 2g; Testa Tritici 2g; 2 parts of Cortex Lycii; 2 parts of Rhizoma Polygonatis; 2 parts of Radix Ginsengs; 2 parts of Radix Rehmanniae Preparata;

Method for preparing:

1) by formula proportion with Radix Puerariae, Radix Paeoniae Alba, Semen Cassiae, Radix Angelicae Sinensis, Testa Tritici, that Rhizoma Polygonati is ground into fine powder is subsequent use;

2) according to formula proportion will remain Chinese herbal medicine clean → screening put into the marmite big fire boil change after 20 minutes slow fire boil 40 minutes → extract supernatant to be cooled to room temperature → filtrate for later use; Slag is added water → decoction again pour into after boil subsequent usely, twice filtrating is mixed until being boiled into the thick paste shape, and it is subsequent use to be cooled to room temperature after bake dry grinding to 300-400 order fine powder;

3) incapsulate after by formula proportion and place the disinfecting container of high temperature >=100 ℃ to carry out disinfection, get product twice subsequent use fine powder mix homogeneously.

Embodiment 2, prescription:

Radix Puerariae 10g; Folium Nelumbinis 10g; Radix Paeoniae Alba 10g; Stigma Maydis 10g; Semen Cassiae 10g; Rhizoma Polygonati Odorati 10g; Folium set Flos potentillae parvifoliae 10g; Folium Eriobotryae 10g; Fructus Mori 6g; Cortex Cinnamomi 6g; Fructus Crataegi 6g; Radix Angelicae Sinensis 6g; Rhizoma Alismatis 6g; Corm Eleocharitis 6g; Semen Ginkgo 6g; Plumula Nelumbinis 6g; Flos Lilii viriduli 4g; Flos Rosae Rugosae 4g; Folium Ginkgo 4g; Flos Rosae Chinensis 4g; Flos Colocasiae Esculentae 4g; Flos Albiziae 4g; Flos Moutan 4g; Radix Ophiopogonis 4g; Fructus Fici 3g; Herba Artemisiae Scopariae 3g; Semen phaseoli radiati 3g; Testa Tritici 3g; Cortex Lycii 3g; Rhizoma Polygonati 3g; Radix Ginseng 3g; Radix Rehmanniae Preparata 3g;

Method for preparing is identical with embodiment 1.

Embodiment 3, prescription:

Radix Puerariae 15g; Folium Nelumbinis 15g; Radix Paeoniae Alba 15g; Stigma Maydis 15g; Semen Cassiae 15g; Rhizoma Polygonati Odorati 15g; Folium set Flos potentillae parvifoliae 15g; Folium Eriobotryae 15g; Fructus Mori 12g; Cortex Cinnamomi 12g; Fructus Crataegi 12g; Radix Angelicae Sinensis 12g; Rhizoma Alismatis 12g; Corm Eleocharitis 12g; Semen Ginkgo 12g; Plumula Nelumbinis 12g; Flos Lilii viriduli 8g; Flos Rosae Rugosae 8g; Folium Ginkgo 8g; Flos Rosae Chinensis 8g; Flos Colocasiae Esculentae 8g; Flos Albiziae 8g; Flos Moutan 8g; Radix Ophiopogonis 8g; Fructus Fici 5g; Herba Artemisiae Scopariae 5g; Semen phaseoli radiati 5g; Testa Tritici 5g; Cortex Lycii 5g; Rhizoma Polygonati 5g; Radix Ginseng 5g; Radix Rehmanniae Preparata 5g;

Method for preparing is identical with embodiment 1.

Embodiment 4, prescription:

Radix Puerariae 18g; Folium Nelumbinis 18g; Radix Paeoniae Alba 18g; Stigma Maydis 18g; Semen Cassiae 18g; Rhizoma Polygonati Odorati 18g; Folium set Flos potentillae parvifoliae 18g; Folium Eriobotryae 18g; Fructus Mori 14g; Cortex Cinnamomi 14g; Fructus Crataegi 14g; Radix Angelicae Sinensis 14g; Rhizoma Alismatis 14g; Corm Eleocharitis 14g; Semen Ginkgo 14g; Plumula Nelumbinis 14g; Flos Lilii viriduli 9g; Flos Rosae Rugosae 9g; Folium Ginkgo 9g; Flos Rosae Chinensis 9g; Flos Colocasiae Esculentae 9g; Flos Albiziae 9g; Flos Moutan 9g; Radix Ophiopogonis 9g; Fructus Fici 7g; Herba Artemisiae Scopariae 7g; Semen phaseoli radiati 7g; Testa Tritici 7g; Cortex Lycii 7g; Rhizoma Polygonati 7g; Radix Ginseng 7g; Radix Rehmanniae Preparata 7g;

Method for preparing is identical with embodiment 1.

Embodiment 5, prescription:

Radix Puerariae 20g; Folium Nelumbinis 20g; Radix Paeoniae Alba 20g; Stigma Maydis 20g; Semen Cassiae 20g; Rhizoma Polygonati Odorati 20g; Folium set Flos potentillae parvifoliae 20g; Folium Eriobotryae 20g; Fructus Mori 15g; Cortex Cinnamomi 15g; Fructus Crataegi 15g; Radix Angelicae Sinensis 15g; Rhizoma Alismatis 15g; Corm Eleocharitis 15g; Semen Ginkgo 15g; Plumula Nelumbinis 15g; Flos Lilii viriduli 10g; Flos Rosae Rugosae 10g; Folium Ginkgo 10g; Flos Rosae Chinensis 10g; Flos Colocasiae Esculentae 10g; Flos Albiziae 10g; Flos Moutan 10g; Radix Ophiopogonis 10g; Fructus Fici 8g; Herba Artemisiae Scopariae 8g; Semen phaseoli radiati 8g; Testa Tritici 8g; Cortex Lycii 8g; Rhizoma Polygonati 8g; Radix Ginseng 8g; Radix Rehmanniae Preparata 8g;

The invention has the beneficial effects as follows:

1, selecting Chinese crude drug for use is raw material, and each component meets pharmacology pharmacy regulation, utilizes the comprehensive function treatment hyperglycemia of the Chinese medicine of respectively distinguishing the flavor of, and gives full play to the little advantage of herbal toxic effect, nontoxic, can take for a long time.

2, we are with blood circulation promoting and blood stasis dispelling; Invigorating the spleen to clear away damp pathogen, YIN nourishing and the production of body fluid promoting are the Therapeutic Principle; Treating both the principal and secondary aspects of a disease, the blood vessels operation is unimpeded, body fluid is sufficient, temper is good for fortune, cerebral blood supply is sufficient, has treated a series of clinical symptoms that hyperglycemia causes; Delay the generation of cerebral arteriosclerosis, improved the quality of people work, life.

Clinical statistics:

Treatment hyperglycemia of the present invention, wherein, male 50 people, women 50 examples, the oldest 79 years old, minimum 39 years old, average 56 years old, disease was had 3 years, weak point person half a year.Treatment every day three times, each 15g, one month is a course of treatment.

Treatment is analyzed:

Cure the result, blood viscosity reduction, cholesterol, triglyceride reduce; Do not heal, blood viscosity does not fall, and blood fat does not fall.

The result treats 100 examples and cures 95 examples, effective percentage 95%.

Model case:

Case 1 :

Lee XX, the woman, 66 years old, disconnected outbreak uncomfortable in chest 2 years, the companion is nervous to breathe hard 6 months.History of present illness: anterior pectorial region uncomfortable in chest malaise symptoms appears in the patient after fatigue or when angry over 2 years.After one week of medication, the patient is uncomfortable in chest, and the nervous attack times of breathing hard reduces to some extent, the time more preceding shortening.The mental status is good, and medication does not have the sensation of oppression over the chest with shortness of breath symptom basically after one month.

Case 2:

Open XX, the man, 55 years old, disconnected outbreak uncomfortable in chest 3 years, the companion is nervous to breathe hard 5 months.Occur anterior pectorial region uncomfortable in chest malaise symptoms over 3 years after fatigue or when angry, can alleviate after the rest, once to local examination in hospital electrocardio diagram: it is low flat that V4 ~ V6 S-t section is forced down the T ripple, the myocardial ischemia performance. be diagnosed as hyperglycemia.Took medication 10 days, the patient is uncomfortable in chest, and the nervous attack times of breathing hard reduces to some extent, the time more preceding shortening.The mental status is good.But still need the nitroglycerin sublingual administration to alleviate during outbreak.After the medication 20 days, patient's doing well,improving is obviously preceding, uncomfortable in chest than two weeks, and the nervous symptom of breathing hard is obviously improved than the last fortnight.Attack times obviously reduces, and degree uncomfortable in chest reduces, and the time shortens, and can alleviate after the rest, does not need the buccal nitroglycerin to alleviate.Medication does not have the sensation of oppression over the chest with shortness of breath symptom after a course of treatment basically.

Case 3:

King XX, the man 33 years old, is admitted to hospital because of the discontinuity Upper abdominal pain increased the weight of 10h in 2 years. and all do not have obvious inducement at every turn and upper left abdomen pain occurs; Under sword, upper right abdomen radiation, the companion feels sick, vomiting, no hepatitis, the preceding blood TG 4.74mmol/L of cholelithiasis history .3, the TC 6.08mmol/L. BP 16/10kPa that haves a medical check-up; Cardiopulmonary (-), abdomen is flat soft, and middle upper abdomen tenderness is obvious, slight rebound tenderness; The liver spleen does not reach, shifting dullness (-). chemical examination TG 3.58mmol/L, TC 10.4mmol/L, Ca 2.38mmol/L; Amylase in urine 655U/L, CT shows edge blurry, has on every side and oozes out. through taking capsule of the present invention, carry out the antiinflammatory glucose-lowering treatment; Remission, TG 2.51mmol/L, TC 4.05mmol/L, amylase in urine 29U/L.

Case 4:

Zhao XX man, 36 years old, 2d was admitted to hospital because of Upper abdominal pain. and occur upper abdominal pain after drinking, do not have the radiation of transfer; Do not accompany nauseating, vomiting. hyperglycemia is previously arranged, TG 4.39mmol/L the year before, TC 7.36mmol/L, no hepatitis, cholelithiasis history. BP 14  6/8kPa have a medical check-up; Cardiopulmonary (-), upper abdomen tenderness, no rebound tenderness, shifting dullness (-); Chemical examination TG 3.97mmol/L, TC 8.05mmol/L, Ca 2.3mmol/L, amylase in urine 1000U/L; CT shows the pancreas anthorisma. through taking capsule of the present invention, carry out treatments such as antiinflammatory blood fat reducing, remission, amylase in urine 50U/L.

Case 5:

Tall XX, the woman, 32 years old, 10h was admitted to hospital because of the persistence Upper abdominal pain. and upper abdominal pain during oil-feed food back occurs is persistence, paroxysmal increases the weight of; Do not have radiation and shift, the companion feels sick, vomiting, and hyperglycemia, no hepatitis, cholelithiasis history are previously arranged. and BP 18/9.3kPa haves a medical check-up; Cardiopulmonary (-), abdomen is flat, and upper abdominal muscle is nervous, and middle upper abdomen tenderness is obvious; No rebound tenderness. chemical examination is shown TG 13.65mmol/L, TC 8.9mmol/L, Ca 2.18mmol/L, TG 4.29mmol/L; TC 6.33mmol/L. carries out treatments such as antiinflammatory blood fat reducing, remission, amylase in urine 50U/L. through taking capsule of the present invention

Case 6:

Liu xx, the man, 50 years old, height 1.72m, body weight 90kg, weak 2 years of main cause is surplus, when in December, 2005 is in our unit's health check-up, looks into fasting glucose 5.9mmol/L, and it is sick not make a definite diagnosis sugared dung.The patient is weak afterwards increases the weight of gradually, and obvious with two lower limb, can not alleviate after the rest.Go to a doctor for asking further the treatment on February 12nd, 2006.Existing main symptom: weak, obvious with two lower limb especially, two just transfer dimly red tongue, thin fur, stringy and thready pulse.Have a medical check-up: one demote situation can, blood pressure 130/85mmHg, the cardiopulmonary feminine gender of having a medical check-up.Previously body is strong, the happiness eating and drinking too much at one meal.Mother is a diabetics in the family.

Treatment process: 1. this patient's obesity of Diet Therapy, eating and drinking without temperance is so adjust dietary structure and custom.Staple food is article such as main, diet Semen Fagopyri Esculenti, Hulless oate with little rice made products.Because of it has fatty liver, anthophagy life less, Semen Benincasae and greasy food 2. Drug therapys (taking medicine of the present invention).3. strengthen physical training, not feel fatigue degree of being after the activity, incremental.4. keep being emotionally stable firm Fighting Disease confidence.5. advise the patient to look in every month on an empty stomach and 3 hours after the meal blood glucose.If after blood glucose was normal in 3 hours after the meal, looked into 2 hours after the meal, 1 hour blood glucose more successively in every month.After 1 month, empty wilful blood glucose 5.2mmol/L, the weak improvement of blood glucose 6.1mmol/L. in 3 hours after the meal. after 3 months, fasting glucose 5.3mmol/L weakly obviously alleviates.After 5 months, 2 hours after the meal blood glucose 7.1mmol/L, transference cure.After 9 months, conscious energetic, whole body is strong.Therapeutic outcome: check on November 2nd, 2008 islet function is following: 1 hour after the meal 2 hours after the meal 3 hours after the meal blood glucose (mmol/l) 4.8 10.1 6.3 5.9 insulins (μ u/ml) 12.7 90.9 58.2 16.1 C-peptides (pmol/ml) 0.54 2.10 1.19 0.55 patients satisfy withdrawal, normal diet on an empty stomach.Looked in per two months in 1 year on an empty stomach and 2 hours after the meal blood glucose all in normal range.Follow up a case by regular visits to not recurrence so far.

Case 7:

Horse xx, woman, 55 years old; The patient was put on the medicated cap of hyperglycemia before 13 years, over 13 years, blood glucose (2 hours after meal) fluctuates between 18.1mmol/L ~ 25mmol/L always; Twenty-four-hour urine sugar often floats between 7.8mmol/L ~ 8.1mmol/L; Simultaneously often with dizziness and tinnitus, edema of lower limbs, smart tired power is weary; Diarrhoea is often arranged, aversion to cold and cold limbs, shallow complexion, fat partially, frequent urination at night (3 ~ 4 times), hyposexuality, blood fat high (cholesterol total amount 10 ~ 15 mmol/L, triglyceride 4 ~ 5 mmol/L), it is poor to sleep, dreaminess.Once took diamicron, insoral, glyburide, metformins etc. have certain effect, but blood glucose one landed vertically less than normal range, and glucose in urine is qualitative often to be "+" or " ++ ".Trial edition invention medicine in 2004 is after 10 days, and blood glucose descends obviously, 10 mmol/L; Glucose in urine "-", above-mentioned sign all disappears simultaneously, after 2 months; Blood glucose drops to 6 mmol/L, twenty-four-hour urine sugar 2.2mmol/L, and the patient is very satisfied; At present conditions of patients is very stable, and the patient also takes continuing, about every day 15 ~ 20ml.

Case 8:

Permitted XX, the woman, 60 years old, patient in June, 2004 is conscious breathes hard, weak, do not have spirit, happiness is drunk water; Can not quench one's thirst again after drinking water, appetite is good, and fat body weight is become thin apparent in view, and diabetes family members history is arranged, and hospital's blood sugar test is unusual; Fasting glucose 8.2 mmol/L, 2 hours after the meal blood glucose 10.3 mmol/L, glucose in urine " ++ " was taken diamicron, restrained sugared profit etc.; Glycemic control is undesirable, and Mental fatigue power is weary, and frequent urination at night is improved not obvious, friend recommendation, trial edition invention pharmaceutical composition; Blood glucose recovers normally gradually after 10 days, and glucose in urine is by " ++ " → "+", after 35 days glucose in urine by "+" → "-", antisecosis, nocturia is by 4 times → 1 time; Sleep, body weight rises gradually, at present, still takes incessantly, and glycemic control is satisfied.

Claims (3)

1. a pharmaceutical composition of treating hyperglycemia is characterized in that, is that the raw material of Chinese medicine compatibility by following weight parts forms:

Radix Puerariae 8-20 part; Folium Nelumbinis 8-20 part; Radix Paeoniae Alba 8-20 part; Stigma Maydis 8-20 part; Semen Cassiae 8-20 part; Rhizoma Polygonati Odorati 8-20 part; Folium set Flos potentillae parvifoliae 8-20 part; Folium Eriobotryae 8-20 part; Fructus Mori 5-15 part; Cortex Cinnamomi 5-15 part; Fructus Crataegi 5-15 part; Radix Angelicae Sinensis 5-15 part; Rhizoma Alismatis 5-15 part; Corm Eleocharitis 5-15 part; Semen Ginkgo 5-15 part; Plumula Nelumbinis 5-15 part; Flos Lilii viriduli 3-10 part; Flos Rosae Rugosae 3-10 part; Folium Ginkgo 3-10 part; Flos Rosae Chinensis 3-10 part; Flos Colocasiae Esculentae 3-10 part; Flos Albiziae 3-10 part; Flos Moutan 3-10 part; Radix Ophiopogonis 3-10 part; Fructus Fici 2-8 part; Herba Artemisiae Scopariae 2-8 part; Semen phaseoli radiati 2-8 part; Testa Tritici 2-8 part; Cortex Lycii 2-8 part; Rhizoma Polygonati 2-8 part; Radix Ginseng 2-8 part; Radix Rehmanniae Preparata 2-8 part;

Method for preparing:

1) by formula proportion with Radix Puerariae, Radix Paeoniae Alba, Semen Cassiae, Radix Angelicae Sinensis, Testa Tritici, that Rhizoma Polygonati is ground into fine powder is subsequent use;

2) according to formula proportion will remain Chinese herbal medicine clean → screening put into the marmite big fire boil change after 20 minutes slow fire boil 40 minutes → extract supernatant to be cooled to room temperature → filtrate for later use; Slag is added water → decoction again pour into after boil subsequent usely, twice filtrating is mixed until being boiled into the thick paste shape, and it is subsequent use to be cooled to room temperature after bake dry grinding to 300-400 order fine powder;

3) incapsulate after by formula proportion and place the disinfecting container of high temperature >=100 ℃ to carry out disinfection, get product twice subsequent use fine powder mix homogeneously.

2. according to claim 1, a kind of pharmaceutical composition of treating hyperglycemia is characterized in that, is that the raw material of Chinese medicine compatibility by following weight parts forms:

Radix Puerariae 10-18 part; Folium Nelumbinis 10-18 part; Radix Paeoniae Alba 10-18 part; Stigma Maydis 10-18 part; Semen Cassiae 10-18 part; Rhizoma Polygonati Odorati 10-18 part; Folium set Flos potentillae parvifoliae 10-18 part; Folium Eriobotryae 10-18 part; Fructus Mori 6-14 part; Cortex Cinnamomi 6-14 part; Fructus Crataegi 6-14 part; Radix Angelicae Sinensis 6-14 part; Rhizoma Alismatis 6-14 part; Corm Eleocharitis 6-14 part; Semen Ginkgo 6-14 part; Plumula Nelumbinis 6-14 part; Flos Lilii viriduli 4-9 part; Flos Rosae Rugosae 4-9 part; Folium Ginkgo 4-9 part; Flos Rosae Chinensis 4-9 part; Flos Colocasiae Esculentae 4-9 part; Flos Albiziae 4-9 part; Flos Moutan 4-9 part; Radix Ophiopogonis 4-9 part; Fructus Fici 3-7 part; Herba Artemisiae Scopariae 3-7 part; Semen phaseoli radiati 3-7 part; Testa Tritici 3-7 part; Cortex Lycii 3-7 part; Rhizoma Polygonati 3-7 part; Radix Ginseng 3-7 part; Radix Rehmanniae Preparata 3-7 part.

3. described according to claims 1, a kind of pharmaceutical composition of treating hyperglycemia, its characteristic sea is, is that the raw material of Chinese medicine compatibility by following weight parts forms:

15 parts of Radix Puerariaes; 15 parts on Folium Nelumbinis; 15 parts of Radix Paeoniae Albas; 15 parts of Stigma Maydis; 15 parts of Semen Cassiaes; 15 parts of Rhizoma Polygonati Odorati; 15 parts of Folium set Flos potentillae parvifoliae; 15 parts of Folium Eriobotryaes; 12 parts in Fructus Mori; 12 parts of Cortex Cinnamomis; 12 parts of Fructus Crataegis; 12 parts of Radix Angelicae Sinensis; 12 parts of Rhizoma Alismatis; 12 parts of Corm Eleocharitiss; 12 parts of Semen Ginkgoes; 12 parts of Plumula Nelumbiniss; 8 parts of Flos Lilii viridulies; 8 parts of Flos Rosae Rugosaes; 8 parts of Folium Ginkgos; 8 parts of Flos Rosae Chinensiss; 8 parts of Flos Colocasiae Esculentaes; 8 parts of Flos Albiziaes; 8 parts of Flos Moutaies; 8 parts of Radix Ophiopogonis; 5 parts of Fructus Ficis; 5 parts of Herba Artemisiae Scopariae; 5 parts in Semen phaseoli radiati; 5 parts of Testa Triticis; 5 parts of Cortex Lycii; 5 parts of Rhizoma Polygonatis; 5 parts of Radix Ginsengs; 5 parts of Radix Rehmanniae Preparata.