CN102762719A - 用于过继细胞疗法的细胞培养的改进方法 - Google Patents

用于过继细胞疗法的细胞培养的改进方法 Download PDF

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CN102762719A
CN102762719A CN2010800637927A CN201080063792A CN102762719A CN 102762719 A CN102762719 A CN 102762719A CN 2010800637927 A CN2010800637927 A CN 2010800637927A CN 201080063792 A CN201080063792 A CN 201080063792A CN 102762719 A CN102762719 A CN 102762719A
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cells
cell
growth
surface density
target
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胡安·F·维拉
克莱奥·M·鲁尼
安·M·里恩
约翰·R·威尔森
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Wilson Wolf Manufacturing LLC
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells

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  • Genetics & Genomics (AREA)
  • Immunology (AREA)
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  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN2010800637927A 2009-12-08 2010-12-08 用于过继细胞疗法的细胞培养的改进方法 Pending CN102762719A (zh)

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US26776109P 2009-12-08 2009-12-08
US61/267,761 2009-12-08
PCT/US2010/059591 WO2011072088A2 (en) 2009-12-08 2010-12-08 Improved methods of cell culture for adoptive cell therapy

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US (1) US8809050B2 (https=)
EP (2) EP2510086A4 (https=)
JP (2) JP2013512694A (https=)
CN (1) CN102762719A (https=)
CA (1) CA2783550A1 (https=)
IL (1) IL220232A0 (https=)
SG (1) SG181559A1 (https=)
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Cited By (2)

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CN105418766A (zh) * 2015-12-22 2016-03-23 深圳市北科生物科技有限公司 一种用于免疫治疗的eb病毒lmp2a串联表位肽及其应用
CN110241086A (zh) * 2012-06-11 2019-09-17 威尔逊沃夫制造公司 用于过继细胞疗法的改进的细胞培养方法

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PT2812431T (pt) 2012-02-09 2019-10-18 Baylor College Medicine Pepmixes para gerar ctls multivirais com larga especifidade
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CN105418766A (zh) * 2015-12-22 2016-03-23 深圳市北科生物科技有限公司 一种用于免疫治疗的eb病毒lmp2a串联表位肽及其应用

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EP2698430A2 (en) 2014-02-19
CA2783550A1 (en) 2011-06-16
US8809050B2 (en) 2014-08-19
WO2011072088A2 (en) 2011-06-16
JP2013512694A (ja) 2013-04-18
IL220232A0 (en) 2012-07-31
WO2011072088A3 (en) 2011-10-13
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