CA2783550A1 - Improved methods of cell culture for adoptive cell therapy - Google Patents

Improved methods of cell culture for adoptive cell therapy Download PDF

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Publication number
CA2783550A1
CA2783550A1 CA2783550A CA2783550A CA2783550A1 CA 2783550 A1 CA2783550 A1 CA 2783550A1 CA 2783550 A CA2783550 A CA 2783550A CA 2783550 A CA2783550 A CA 2783550A CA 2783550 A1 CA2783550 A1 CA 2783550A1
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CA
Canada
Prior art keywords
cells
cell
surface density
growth
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2783550A
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English (en)
French (fr)
Inventor
Juan F. Vera
Clio M. Rooney
Ann M. Leen
John R. Wilson
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Wilson Wolf Manufacturing LLC
Original Assignee
Wilson Wolf Manufacturing LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Wilson Wolf Manufacturing LLC filed Critical Wilson Wolf Manufacturing LLC
Publication of CA2783550A1 publication Critical patent/CA2783550A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2783550A 2009-12-08 2010-12-08 Improved methods of cell culture for adoptive cell therapy Abandoned CA2783550A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26776109P 2009-12-08 2009-12-08
US61/267,761 2009-12-08
PCT/US2010/059591 WO2011072088A2 (en) 2009-12-08 2010-12-08 Improved methods of cell culture for adoptive cell therapy

Publications (1)

Publication Number Publication Date
CA2783550A1 true CA2783550A1 (en) 2011-06-16

Family

ID=44082417

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2783550A Abandoned CA2783550A1 (en) 2009-12-08 2010-12-08 Improved methods of cell culture for adoptive cell therapy

Country Status (8)

Country Link
US (1) US8809050B2 (https=)
EP (2) EP2510086A4 (https=)
JP (2) JP2013512694A (https=)
CN (1) CN102762719A (https=)
CA (1) CA2783550A1 (https=)
IL (1) IL220232A0 (https=)
SG (1) SG181559A1 (https=)
WO (1) WO2011072088A2 (https=)

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Also Published As

Publication number Publication date
SG181559A1 (en) 2012-07-30
EP2698430A3 (en) 2014-03-05
JP2015133997A (ja) 2015-07-27
EP2698430A2 (en) 2014-02-19
US8809050B2 (en) 2014-08-19
WO2011072088A2 (en) 2011-06-16
JP2013512694A (ja) 2013-04-18
IL220232A0 (en) 2012-07-31
WO2011072088A3 (en) 2011-10-13
EP2510086A2 (en) 2012-10-17
US20110136228A1 (en) 2011-06-09
CN102762719A (zh) 2012-10-31
EP2510086A4 (en) 2013-05-22

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