CN102648286A - 在巴斯德毕赤氏酵母中生产缺乏与针对宿主细胞抗原的抗体的可检测交叉结合活性的蛋白质的方法 - Google Patents

在巴斯德毕赤氏酵母中生产缺乏与针对宿主细胞抗原的抗体的可检测交叉结合活性的蛋白质的方法 Download PDF

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CN102648286A
CN102648286A CN2010800577907A CN201080057790A CN102648286A CN 102648286 A CN102648286 A CN 102648286A CN 2010800577907 A CN2010800577907 A CN 2010800577907A CN 201080057790 A CN201080057790 A CN 201080057790A CN 102648286 A CN102648286 A CN 102648286A
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host cell
glycan
antibody
pichia pastoris
gene
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P.多布罗维奇
S.戈马蒂纳亚加姆
S.哈密尔顿
H.李
N.塞图拉曼
T.A.斯塔黑姆
S.维尔德特
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Merck Sharp and Dohme LLC
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Schering Corp
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CN2010800577907A 2009-10-16 2010-10-11 在巴斯德毕赤氏酵母中生产缺乏与针对宿主细胞抗原的抗体的可检测交叉结合活性的蛋白质的方法 Pending CN102648286A (zh)

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US25231209P 2009-10-16 2009-10-16
US61/252,312 2009-10-16
PCT/US2010/052140 WO2011046855A1 (fr) 2009-10-16 2010-10-11 Procédé de production de protéines dans pichia pastoris exemptes d'activité détectable de liaison croisée à des anticorps dirigés contre des antigènes de cellule hôte

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CN201410094457.3A Pending CN104031961A (zh) 2009-10-16 2010-10-11 生产成熟的人促红细胞生成素的方法以及包含获自该方法的人促红细胞生成素的组合物

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US (2) US9139632B2 (fr)
EP (1) EP2488657B1 (fr)
JP (1) JP2013507921A (fr)
KR (1) KR20120084734A (fr)
CN (2) CN102648286A (fr)
AU (1) AU2010307098A1 (fr)
BR (1) BR112012008862A2 (fr)
CA (1) CA2776392A1 (fr)
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110684771A (zh) * 2019-10-30 2020-01-14 福建师范大学 一种不受甘油和葡萄糖抑制的可诱导启动子及利用该启动子构建的毕赤酵母表达载体
CN112888315A (zh) * 2018-08-21 2021-06-01 克莱拉食品公司 微生物中的蛋白质糖基化的修饰
CN113549560A (zh) * 2020-04-24 2021-10-26 中国人民解放军军事科学院军事医学研究院 一种用于糖蛋白制备的工程化酵母构建方法及其菌株
CN113621041A (zh) * 2021-09-26 2021-11-09 江南大学 一种截短的马铃薯糖蛋白Patatin及其制备方法
CN113754739A (zh) * 2020-06-03 2021-12-07 中国人民解放军军事科学院军事医学研究院 一种冠状病毒s蛋白rbd糖蛋白的制备方法及其应用

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US9139632B2 (en) 2015-09-22
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US20120232007A1 (en) 2012-09-13
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US20140200180A1 (en) 2014-07-17
BR112012008862A2 (pt) 2019-09-24
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