CN102641473A - Compound propolis composition for curing chicken infectivity coryza and preparation method thereof - Google Patents
Compound propolis composition for curing chicken infectivity coryza and preparation method thereof Download PDFInfo
- Publication number
- CN102641473A CN102641473A CN2012101336699A CN201210133669A CN102641473A CN 102641473 A CN102641473 A CN 102641473A CN 2012101336699 A CN2012101336699 A CN 2012101336699A CN 201210133669 A CN201210133669 A CN 201210133669A CN 102641473 A CN102641473 A CN 102641473A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- coryza
- preparation
- chicken
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A compound propolis composition for curing chicken infectivity coryza and a preparation method thereof relate to the field of animal drugs. The compound propolis composition is formed by the following ingredients by parts of weight: 15-35 parts of propolis, 10-35 parts of honeysuckle, 15-30 parts of isatis root, 10-25 parts of oriental wormwood, 10-35 parts of radices sileris, 15-35 parts of liquorice, 10-35 parts of rhizoma atractylodis, 10-35 parts of tint, 10-35 parts of radix curcumae, 10-35 parts of elecampane and 10-35 parts of rhizoma anemarrhenae. The compound propolis composition has the advantages of being reasonable in formula, simple in preparation, free of toxic and side effect, free of pollution, free of drug residue, free of drug resistance, high in superfine grinding and biological utilization rate and obvious in treatment. Clinical tests show that the compound propolis composition has special effects on curing chicken infectivity coryza.
Description
Technical field
The present invention relates to compound bee-glue composition of treating infectious coryza of chicken and preparation method thereof, belong to the animal field of medicaments, particularly a kind of compound bee-glue composition that is specifically designed to the treatment infectious coryza of chicken and preparation method thereof.
Background technology
Infectious coryza of chicken is a kind of acute respiratory infectious disease that is caused by haemophilus paragallinarum.The chicken of various ages and kind all can infect, and is comparatively responsive with the chicken more than 4 ages in week.It is characterized in that nasal cavity and nasal sinuses inflammation, sneeze, stream nose liquid, face swelling, conjunctivitis etc.Primary disease is propagated rapidly, mortality rate generally between 5%-20%, the laying rate 20%-50% that can descend.This cold season disease autumn and winter is multiple, is one of principal disease of harm poultry husbandry.
The pathogen of primary disease is a haemophilus paragallinarum, under cryogenic conditions, but 10 years time-to-live.This disease almost spreads all over all countries of raising chickens of the world, distributes very extensively.At present, treat this disease the most frequently used be Chinese medicine and antimicrobial drug, Chinese medicine is because its prescription is unreasonable or just simple the pulverizing, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; And various antibacterials such as streptomycin sulfate, florfenicol etc. are because prolonged and repeated use; Cause this pathogenic microorganism that medicine has been produced drug resistance, reduced curative effect, and drug residue is in animal product; Do not reach nuisanceless requirement, influenced the outlet of animal products and people's health.
Therefore researching and developing a kind of drug residue free of infectious coryza of chicken, generations that have no drug resistance, the significant specific medicament of clinical effectiveness of treating is one of this field scientific research technical staff urgency new problem to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability are high, effect obviously, have no drug resistance and the compound bee-glue composition of effective treatment infectious coryza of chicken of drug residue and preparation method thereof.
For realizing above-mentioned purpose; The embodiment that the present invention adopted is following: a kind of compound bee-glue composition of treating infectious coryza of chicken, by following component by weight mixed preparing form: propolis 15-35 part, Flos Lonicerae 10-35 part, Radix Isatidis 15-30 part, Herba Artemisiae Scopariae 10-25 part, windproof 10-35 part, Radix Glycyrrhizae 15-35 part, Rhizoma Atractylodis 10-35 part, Herba Menthae 10-35 part, Radix Curcumae 10-35 part, Radix Aucklandiae 10-35 part, Rhizoma Anemarrhenae 10-35 part.
On the basis of such scheme, said various component optimum ratio amounts are: 25 parts of propolis, 25 parts of Flos Loniceraes, 20 parts of Radix Isatidis, 15 parts of Herba Artemisiae Scopariaes, windproof 25 parts, 25 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Atractylodis, 20 parts of Herba Menthaes, 20 parts of Radix Curcumaes, 20 parts of the Radix Aucklandiae, 20 parts of the Rhizoma Anemarrhenaes.
A kind of method for preparing of treating the compound bee-glue composition of infectious coryza of chicken, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Flos Lonicerae 10-35 part, Radix Isatidis 15-30 part, Herba Artemisiae Scopariae 10-25 part, windproof 10-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Glycyrrhizae 15-35 part, Rhizoma Atractylodis 10-35 part, Herba Menthae 10-35 part, Radix Curcumae 10-35 part, Radix Aucklandiae 10-35 part, Rhizoma Anemarrhenae 10-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Propolis: bitter, hot, cold, return spleen, stomach warp, have the function of anti-inflammation, antalgesic-antipruritic, promotion tissue regeneration, raising immunity, antiallergic oxidation, hemostasis, protection gastrointestinal mucosa.
Flos Lonicerae: sweet, cold, attach to the lung and stomach meridians, have the function of heat-clearing and toxic substances removing, heat radiation dispelling wind; Cure mainly cough due to lung-heat, epidemic febrile disease heating, laryngopharynx swelling and pain, toxic-heat and blood stasis, carbuncle sore tumefacting virus etc.
Radix Isatidis: bitter, cold, GUIXIN, stomach warp have the function of heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving; Cure mainly anemopyretic cold, laryngopharynx swelling and pain, aphtha of the mouth and tongue, skin ulcer general edema with yellowish skin poison etc.
Herba Artemisiae Scopariae: bitter, hot, be slightly cold, return spleen, stomach, liver, gallbladder meridian, have the function of eliminating damp-heat, promoting the function of the gallbladder to alleviate jaundice; It is overworked etc. to cure mainly jaundice, oliguria, eczema scabies.
Windproof: hot, sweet, warm, return liver, spleen, urinary bladder channel, have inducing diaphoresis to dispel wind, win function wet, spasmolytic; Cure mainly affection of exogenous wind-cold, anemofrigid-damp arthralgia, rubella pruritus, tetanus etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
Rhizoma Atractylodis: bitter, hot, warm, return spleen, stomach, Liver Channel, the function that have drying damp and strengthening spleen, expelling wind and cold, makes eye bright; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia etc.
Herba Menthae: hot, cool, return lung, Liver Channel, have the function of wind-dispelling heat-dissipating, the cleaning head, sore-throat relieving, rash; Cure mainly affection due to external wind and heat, laryngopharynx swelling and pain, conjunctival congestion, rubella etc.
Radix Curcumae: bitter, hot, cold, return lung, liver, heart channel, have the function of promoting QI circulation for relieving depression, removing heat from blood and promoting blood circulation, promoting the function of the gallbladder to alleviate jaundice; Cure mainly that distension and fullness of the chest and abdomen, intestinal Huang are had loose bowels, calentura coma, jaundice due to damp-heat etc.
The Radix Aucklandiae: hot, bitter, warm, return spleen, stomach, large intestine, three warmers, gallbladder meridian, have the function of promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion; Cure mainly that the gastrointestinal stagnation of QI, food stagnation tripe expand, weight, stomachache etc. behind the dysentery.
The Rhizoma Anemarrhenae: bitter, sweet, cold, return lung, stomach, kidney channel, have clearing away heat-fire, nourshing Yin and drynsessmoistening prescription function; Cure mainly fever caused by exogenous pathogenic factors, gastric heat, cough due to lung-heat, dryness of the intestine constipation, interior-heat caused by deficiency of YIN etc.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, to the pathogenic microorganism and the clinical symptoms of infectious coryza of chicken, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, and micronizing, bioavailability are high, can also can drink water the curative effect highly significant by spice.The present invention is according to Chinese veterinarian's traditional theory; Optimize this seven flavors Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves; The treatment infectious coryza of chicken there is specially good effect; And make its product reach nuisanceless requirement, satisfy the export standard of product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound bee-glue composition of treating infectious coryza of chicken and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of propolis, 100 parts of Flos Loniceraes, 150 parts of Radix Isatidis, 100 parts of Herba Artemisiae Scopariaes, windproof 100 parts by weight, mix 5-10 minute to evenly;
(3) take by weighing 150 parts in Radix Glycyrrhizae, 100 parts of Rhizoma Atractylodis, 100 parts of Herba Menthaes, 100 parts of Radix Curcumaes, 100 parts of the Radix Aucklandiae, 100 parts of the Rhizoma Anemarrhenaes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound bee-glue composition of treating infectious coryza of chicken and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts of propolis, 150 parts of Flos Loniceraes, 250 parts of Radix Isatidis, 150 parts of Herba Artemisiae Scopariaes, windproof 250 parts by weight, mix 5-10 minute to evenly;
(3) take by weighing 250 parts in Radix Glycyrrhizae, 200 parts of Rhizoma Atractylodis, 200 parts of Herba Menthaes, 200 parts of Radix Curcumaes, 200 parts of the Radix Aucklandiae, Rhizoma Anemarrhenae 10-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound bee-glue composition of treating infectious coryza of chicken and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts of propolis, 350 parts of Flos Loniceraes, 300 parts of Radix Isatidis, 250 parts of Herba Artemisiae Scopariaes, windproof 350 parts by weight, mix 5-10 minute to evenly;
(3) take by weighing 350 parts in Radix Glycyrrhizae, 350 parts of Rhizoma Atractylodis, 350 parts of Herba Menthaes, 350 parts of Radix Curcumaes, 350 parts of the Radix Aucklandiae, 350 parts of the Rhizoma Anemarrhenaes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects for use 180-240 age in days, body weight at 1.5kg-2.8kg, and laboratory is diagnosed as the ill laying hen of infectious coryza of chicken.Ill chicken is isolated raising separately, the complete feed of feeding, and be divided into 3 groups at random, and 30 every group, 3 groups of feeding environments are identical, and experimental period was carried out 7 days altogether; The blank group is left intact, and the medicine matched group uses treatment with institute's control drug by its description; Chinese medicine composition group of the present invention is with the ill poultry of product feeding of the present invention etc., and a day dose is: by the every 100g of the present invention, spice 150kg feeds, drinking-water 240kg, every day 2-3 time, logotype 3-5 day; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.Result's (testing the 8th day) when following table is the experiment end.
Table is the field applicable cases contrast of the present invention and other medicines treatment infectious coryza of chicken:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 11.1 | 45.5 | 43.4 |
| II | BIYANKANG looses and organizes | 7.0 | 79.9 | 13.1 |
| III | Chinese medicine composition of the present invention | 5.2 | 88.5 | 6.3 |
This clinical effectiveness is through statistical analysis, and present composition treatment group is loose to organize with BIYANKANG and compared difference extremely significantly (P＜0.01) aspect the cure rate.
Above-mentioned detailed description of compound bee-glue composition of this treatment infectious coryza of chicken and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. compound bee-glue composition of treating infectious coryza of chicken, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Flos Lonicerae 10-35 part, Radix Isatidis 15-30 part, Herba Artemisiae Scopariae 10-25 part, windproof 10-35 part, Radix Glycyrrhizae 15-35 part, Rhizoma Atractylodis 10-35 part, Herba Menthae 10-35 part, Radix Curcumae 10-35 part, Radix Aucklandiae 10-35 part, Rhizoma Anemarrhenae 10-35 part.
2. the compound bee-glue composition of treatment infectious coryza of chicken according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of propolis, 25 parts of Flos Loniceraes, 20 parts of Radix Isatidis, 15 parts of Herba Artemisiae Scopariaes, windproof 25 parts, 25 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Atractylodis, 20 parts of Herba Menthaes, 20 parts of Radix Curcumaes, 20 parts of the Radix Aucklandiae, 20 parts of the Rhizoma Anemarrhenaes.
3. the method for preparing of the compound bee-glue composition of a treatment infectious coryza of chicken according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Flos Lonicerae 10-35 part, Radix Isatidis 15-30 part, Herba Artemisiae Scopariae 10-25 part, windproof 10-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Glycyrrhizae 15-35 part, Rhizoma Atractylodis 10-35 part, Herba Menthae 10-35 part, Radix Curcumae 10-35 part, Radix Aucklandiae 10-35 part, Rhizoma Anemarrhenae 10-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210133669.9A CN102641473B (en) | 2012-05-03 | 2012-05-03 | Compound propolis composition for curing chicken infectivity coryza and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210133669.9A CN102641473B (en) | 2012-05-03 | 2012-05-03 | Compound propolis composition for curing chicken infectivity coryza and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102641473A true CN102641473A (en) | 2012-08-22 |
| CN102641473B CN102641473B (en) | 2014-02-12 |
Family
ID=46654715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210133669.9A Expired - Fee Related CN102641473B (en) | 2012-05-03 | 2012-05-03 | Compound propolis composition for curing chicken infectivity coryza and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102641473B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004560A (en) * | 1998-11-16 | 1999-12-21 | Hsu; Wu-Ching | Nasal spray (drop) for treating fever/cold, and its preparation |
| CN1899566A (en) * | 2006-07-05 | 2007-01-24 | 河北农业大学 | Medicine for preventing and controlling chicken's infectious rhinitis |
| JP2011205952A (en) * | 2010-03-29 | 2011-10-20 | Kazuhiko Ikeda | Deactivator for virus and bacterium, and feed for fowl comprising the same |
| KR20110125318A (en) * | 2010-05-13 | 2011-11-21 | 주식회사 대산 | Antibiotic composition comprising plants extract mixture |
-
2012
- 2012-05-03 CN CN201210133669.9A patent/CN102641473B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004560A (en) * | 1998-11-16 | 1999-12-21 | Hsu; Wu-Ching | Nasal spray (drop) for treating fever/cold, and its preparation |
| CN1899566A (en) * | 2006-07-05 | 2007-01-24 | 河北农业大学 | Medicine for preventing and controlling chicken's infectious rhinitis |
| JP2011205952A (en) * | 2010-03-29 | 2011-10-20 | Kazuhiko Ikeda | Deactivator for virus and bacterium, and feed for fowl comprising the same |
| KR20110125318A (en) * | 2010-05-13 | 2011-11-21 | 주식회사 대산 | Antibiotic composition comprising plants extract mixture |
Non-Patent Citations (4)
| Title |
|---|
| 《云南畜牧兽医》 20101231 余明翠等 一起产蛋鸡暴发传染性鼻炎的诊治 第12页，尤其右栏倒数第8-11行 1-3 , 第4期 * |
| 余明翠等: "一起产蛋鸡暴发传染性鼻炎的诊治", 《云南畜牧兽医》 * |
| 凌育: "如何用中草药防治鸡病", 《北京科技报》 * |
| 谢麟等: "《动物药剂的应用与制作科技全书》", 31 August 2002, 四川科学技术出版社 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102641473B (en) | 2014-02-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102784219B (en) | Compound pure Chinese medicine composition for treating bovine ephemeral fever and preparation method of same | |
| CN102961636B (en) | Pure traditional Chinese medicine composition for treating poultry infectious bursal disease and preparation method thereof | |
| CN102727770B (en) | Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof | |
| CN102813809B (en) | Pure traditional Chinese medicine composition for treating chronic respiratory disease of poultry as well as preparation method thereof | |
| CN102784243A (en) | Pure Chinese medicine composition for treating cattle flu and preparation method of same | |
| CN102727848B (en) | Pure traditional Chinese medicine composition used for treating poultry infectious bursal disease, and preparation method thereof | |
| CN102727693B (en) | Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof | |
| CN102935149B (en) | A kind of composition and method of making the same for the treatment of domestic animal respiratory tract disease | |
| CN102488881B (en) | Compound propolis composition for promoting pig growth and fattening as well as its preparation method | |
| CN103599362A (en) | Traditional Chinese medicine composition for treating swine enzootic pneumonia and preparation method thereof | |
| CN102784371B (en) | Pure traditional medicine composition for treating swine flu and preparation method of pure traditional medicine composition | |
| CN102370706B (en) | Compound propolis composition for treating infectious rhinitis of chickens and preparation method thereof | |
| CN102743669B (en) | Compound propolis composition for treating swine enzootic pneumonia | |
| CN102670804B (en) | Compound propolis composition for treating poultry dysentery and preparation method thereof | |
| CN102397533B (en) | Compound propolis composition for treating livestock egg drop syndrome and preparation method thereof | |
| CN102641473B (en) | Compound propolis composition for curing chicken infectivity coryza and preparation method thereof | |
| CN102743508B (en) | Compound propolis composition for treating avian infectious laryngotracheitis and preparation method thereof | |
| CN103585407A (en) | Traditional Chinese medicine composition for treating swine infectious atrophic rhinitis and preparation method of composition | |
| CN102727669B (en) | Compound propolis composition used for treating swine erysipelas, and preparation method thereof | |
| CN102499979B (en) | Compound propolis composition for treating dog and cat diarrhea and preparation method thereof | |
| CN102671122B (en) | Compound pure Chinese medicinal composition for treating livestock gastric-enteritis and preparation method thereof | |
| CN102935139A (en) | Compound propolis composition for treating chronic gastroenteritis of livestock and preparation method of composition | |
| CN102488892B (en) | Composite propolis composition used for treating unknown swine high-fever, and preparation method thereof | |
| CN102670761B (en) | Pure traditional Chinese medicine composition for treating infectious bursal disease of poultry and preparation method thereof | |
| CN102961568B (en) | Compound bee-glue composition for the treatment of unknown high fever of pigs and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140212 Termination date: 20160503 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |