CN102532128B - 托烷司琼的合成方法以及盐酸托烷司琼的制备方法 - Google Patents
托烷司琼的合成方法以及盐酸托烷司琼的制备方法 Download PDFInfo
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CN102532128B true CN102532128B (zh) | 2014-11-12 |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102887893B (zh) * | 2012-10-24 | 2015-01-14 | 齐鲁制药有限公司 | 一种托烷司琼的制备方法 |
CN104945397B (zh) * | 2015-07-30 | 2016-08-24 | 烟台市蓝洋之草医药生物科技有限公司 | 治疗恶心和呕吐的药物盐酸托烷司琼化合物及其制备方法 |
CN106831754A (zh) * | 2015-12-03 | 2017-06-13 | 康普药业股份有限公司 | 一种盐酸托烷司琼的制备方法 |
US11583842B2 (en) | 2019-07-24 | 2023-02-21 | The Chinese University Of Hong Kong | Zwitterionic catalysts for (trans)esterification: application in fluoroindole-derivatives and biodiesel synthesis |
CN110845493B (zh) * | 2019-11-04 | 2021-09-10 | 植恩生物技术股份有限公司 | 盐酸托烷司琼的制备方法 |
Citations (6)
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US4789673A (en) * | 1982-07-13 | 1988-12-06 | Peter Donatsch | Heterocyclic carboxylic acid amides and esters |
US4797406A (en) * | 1983-08-26 | 1989-01-10 | Sandoz Ltd. | Amides and esters containing bridged piperidines and use as serotonin M antagonists |
CN1305994A (zh) * | 2000-12-08 | 2001-08-01 | 中国科学院上海有机化学研究所 | (3r,5r)-3,5-二羟基-7-n-邻苯二甲酰亚胺基-庚酸叔丁酯、合成及用途 |
CN101033225A (zh) * | 2007-04-02 | 2007-09-12 | 北京成宇化工有限公司 | 托烷司琼的制备工艺 |
CN101781214A (zh) * | 2009-12-10 | 2010-07-21 | 张家界奥威科技有限公司 | 没食子酸正辛酯过量酯化生产工艺 |
CN101787021A (zh) * | 2010-03-05 | 2010-07-28 | 王明 | 一种高纯度的盐酸托烷司琼化合物 |
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2010
- 2010-12-17 CN CN201010595050.0A patent/CN102532128B/zh active Active
Patent Citations (6)
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---|---|---|---|---|
US4789673A (en) * | 1982-07-13 | 1988-12-06 | Peter Donatsch | Heterocyclic carboxylic acid amides and esters |
US4797406A (en) * | 1983-08-26 | 1989-01-10 | Sandoz Ltd. | Amides and esters containing bridged piperidines and use as serotonin M antagonists |
CN1305994A (zh) * | 2000-12-08 | 2001-08-01 | 中国科学院上海有机化学研究所 | (3r,5r)-3,5-二羟基-7-n-邻苯二甲酰亚胺基-庚酸叔丁酯、合成及用途 |
CN101033225A (zh) * | 2007-04-02 | 2007-09-12 | 北京成宇化工有限公司 | 托烷司琼的制备工艺 |
CN101781214A (zh) * | 2009-12-10 | 2010-07-21 | 张家界奥威科技有限公司 | 没食子酸正辛酯过量酯化生产工艺 |
CN101787021A (zh) * | 2010-03-05 | 2010-07-28 | 王明 | 一种高纯度的盐酸托烷司琼化合物 |
Non-Patent Citations (4)
Title |
---|
New Potent Indole Derivatives as Hyaluronidase Inhibitors;Sureyya Olgen1 等;《Chem Biol Drug Des》;20071231;第70卷(第6期);第547-551页 * |
Sureyya Olgen1 等.New Potent Indole Derivatives as Hyaluronidase Inhibitors.《Chem Biol Drug Des》.2007,第70卷(第6期),第547-551页. * |
盐酸托烷司琼的合成改进;程青芳 等;《淮海工学院学报》;20031231;第12卷(第4期);第41-43页 * |
程青芳 等.盐酸托烷司琼的合成改进.《淮海工学院学报》.2003,第12卷(第4期),第41-43页. * |
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Address after: 100871, Beijing, Haidian District, Cheng Fu Road, No. 298, Zhongguancun Fangzheng building, 5 floor Patentee after: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee after: PKU HEALTHCARE Corp.,Ltd. Patentee after: PKU HEALTHCARE INDUSTRY Group Address before: 100871, Beijing, Haidian District, Cheng Fu Road, No. 298, Zhongguancun Fangzheng building, 5 floor Patentee before: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee before: SOUTHWEST SYNTHETIC PHARMACEUTICAL Corp.,Ltd. Patentee before: Pku Healthcare Industry Group Co.,Ltd. |
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