CN102532128A - 托烷司琼的合成方法以及盐酸托烷司琼的制备方法 - Google Patents
托烷司琼的合成方法以及盐酸托烷司琼的制备方法 Download PDFInfo
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102887893A (zh) * | 2012-10-24 | 2013-01-23 | 齐鲁制药有限公司 | 一种托烷司琼的制备方法 |
CN104945397A (zh) * | 2015-07-30 | 2015-09-30 | 青岛蓝盛洋医药生物科技有限责任公司 | 治疗恶心和呕吐的药物盐酸托烷司琼化合物及其制备方法 |
CN106831754A (zh) * | 2015-12-03 | 2017-06-13 | 康普药业股份有限公司 | 一种盐酸托烷司琼的制备方法 |
CN110845493A (zh) * | 2019-11-04 | 2020-02-28 | 重庆植恩药业有限公司 | 盐酸托烷司琼的制备方法 |
CN112275318A (zh) * | 2019-07-24 | 2021-01-29 | 香港中文大学 | 用于(酯交换)酯化的两性离子催化剂:在氟吲哚衍生物和生物柴油合成中的应用 |
Citations (6)
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US4789673A (en) * | 1982-07-13 | 1988-12-06 | Peter Donatsch | Heterocyclic carboxylic acid amides and esters |
US4797406A (en) * | 1983-08-26 | 1989-01-10 | Sandoz Ltd. | Amides and esters containing bridged piperidines and use as serotonin M antagonists |
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CN101033225A (zh) * | 2007-04-02 | 2007-09-12 | 北京成宇化工有限公司 | 托烷司琼的制备工艺 |
CN101781214A (zh) * | 2009-12-10 | 2010-07-21 | 张家界奥威科技有限公司 | 没食子酸正辛酯过量酯化生产工艺 |
CN101787021A (zh) * | 2010-03-05 | 2010-07-28 | 王明 | 一种高纯度的盐酸托烷司琼化合物 |
-
2010
- 2010-12-17 CN CN201010595050.0A patent/CN102532128B/zh active Active
Patent Citations (6)
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US4789673A (en) * | 1982-07-13 | 1988-12-06 | Peter Donatsch | Heterocyclic carboxylic acid amides and esters |
US4797406A (en) * | 1983-08-26 | 1989-01-10 | Sandoz Ltd. | Amides and esters containing bridged piperidines and use as serotonin M antagonists |
CN1305994A (zh) * | 2000-12-08 | 2001-08-01 | 中国科学院上海有机化学研究所 | (3r,5r)-3,5-二羟基-7-n-邻苯二甲酰亚胺基-庚酸叔丁酯、合成及用途 |
CN101033225A (zh) * | 2007-04-02 | 2007-09-12 | 北京成宇化工有限公司 | 托烷司琼的制备工艺 |
CN101781214A (zh) * | 2009-12-10 | 2010-07-21 | 张家界奥威科技有限公司 | 没食子酸正辛酯过量酯化生产工艺 |
CN101787021A (zh) * | 2010-03-05 | 2010-07-28 | 王明 | 一种高纯度的盐酸托烷司琼化合物 |
Non-Patent Citations (2)
Title |
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SUREYYA OLGEN1 等: "New Potent Indole Derivatives as Hyaluronidase Inhibitors", 《CHEM BIOL DRUG DES》, vol. 70, no. 6, 31 December 2007 (2007-12-31), pages 547 - 551, XP002514495, DOI: doi:10.1111/J.1747-0285.2007.00590.X * |
程青芳 等: "盐酸托烷司琼的合成改进", 《淮海工学院学报》, vol. 12, no. 4, 31 December 2003 (2003-12-31), pages 41 - 43 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102887893A (zh) * | 2012-10-24 | 2013-01-23 | 齐鲁制药有限公司 | 一种托烷司琼的制备方法 |
CN104945397A (zh) * | 2015-07-30 | 2015-09-30 | 青岛蓝盛洋医药生物科技有限责任公司 | 治疗恶心和呕吐的药物盐酸托烷司琼化合物及其制备方法 |
CN106831754A (zh) * | 2015-12-03 | 2017-06-13 | 康普药业股份有限公司 | 一种盐酸托烷司琼的制备方法 |
CN112275318A (zh) * | 2019-07-24 | 2021-01-29 | 香港中文大学 | 用于(酯交换)酯化的两性离子催化剂:在氟吲哚衍生物和生物柴油合成中的应用 |
US11583842B2 (en) | 2019-07-24 | 2023-02-21 | The Chinese University Of Hong Kong | Zwitterionic catalysts for (trans)esterification: application in fluoroindole-derivatives and biodiesel synthesis |
CN110845493A (zh) * | 2019-11-04 | 2020-02-28 | 重庆植恩药业有限公司 | 盐酸托烷司琼的制备方法 |
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