CN102482664A - 用于预测c型肝炎的治疗效果的标记物和预测c型肝炎的治疗效果的方法以及c型肝炎的预防或治疗剂 - Google Patents
用于预测c型肝炎的治疗效果的标记物和预测c型肝炎的治疗效果的方法以及c型肝炎的预防或治疗剂 Download PDFInfo
- Publication number
- CN102482664A CN102482664A CN2010800365956A CN201080036595A CN102482664A CN 102482664 A CN102482664 A CN 102482664A CN 2010800365956 A CN2010800365956 A CN 2010800365956A CN 201080036595 A CN201080036595 A CN 201080036595A CN 102482664 A CN102482664 A CN 102482664A
- Authority
- CN
- China
- Prior art keywords
- hepatitis
- therapeutic effect
- polynucleotide
- oligonucleotide
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009-192615 | 2009-08-21 | ||
| JP2009192615A JP5727694B2 (ja) | 2009-08-21 | 2009-08-21 | C型肝炎の治療効果を予測するためのマーカー及びc型肝炎の治療効果の予測を行う方法並びにc型肝炎の予防又は治療剤 |
| PCT/JP2010/063262 WO2011021508A1 (ja) | 2009-08-21 | 2010-08-05 | C型肝炎の治療効果を予測するためのマーカー及びc型肝炎の治療効果の予測を行う方法並びにc型肝炎の予防又は治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102482664A true CN102482664A (zh) | 2012-05-30 |
Family
ID=43606963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800365956A Pending CN102482664A (zh) | 2009-08-21 | 2010-08-05 | 用于预测c型肝炎的治疗效果的标记物和预测c型肝炎的治疗效果的方法以及c型肝炎的预防或治疗剂 |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP5727694B2 (enExample) |
| CN (1) | CN102482664A (enExample) |
| WO (1) | WO2011021508A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102816838A (zh) * | 2012-07-06 | 2012-12-12 | 吉林艾迪康医学检验所有限公司 | 用于检测丙型肝炎患者il28b snp12980275多态性的试剂盒 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5656159B2 (ja) * | 2009-08-24 | 2015-01-21 | 独立行政法人理化学研究所 | インターフェロン療法の効果予測用マーカー |
| JP5787337B2 (ja) * | 2010-03-19 | 2015-09-30 | 公益財団法人ヒューマンサイエンス振興財団 | C型肝炎の治療効果を予測するためのマーカー群、検査方法及び検査用キット |
| EP2691094A1 (en) * | 2011-03-31 | 2014-02-05 | Novartis AG | Alisporivir to treat hepatitis c virus infection |
| CN103074417B (zh) * | 2012-06-20 | 2015-06-24 | 宁波海尔施基因科技有限公司 | 一种丙型肝炎治疗用药指导的多重基因检测方法 |
| US20160053309A1 (en) | 2013-03-26 | 2016-02-25 | Nippon Gene Co., Ltd. | Set of primers and probes to be used for identification of gene polymorphism and use thereof |
| JP6155750B2 (ja) * | 2013-03-27 | 2017-07-05 | 東洋紡株式会社 | SNP(rs11881222)を検出するためのプローブ |
-
2009
- 2009-08-21 JP JP2009192615A patent/JP5727694B2/ja active Active
-
2010
- 2010-08-05 WO PCT/JP2010/063262 patent/WO2011021508A1/ja not_active Ceased
- 2010-08-05 CN CN2010800365956A patent/CN102482664A/zh active Pending
Non-Patent Citations (4)
| Title |
|---|
| DONGLIANG GE ET AL.: "Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance", 《NATURE》 * |
| NAZIA SELZNER IAN MCGILVRAY: "Can genetic variations predict HCV treatment outcomes?", 《JOURNAL OF HEPATOLOGY》 * |
| TIMOTHY R. MORGAN ET AL.: "DNA polymorphisms and response to treatment in patients with chronic hepatitis C:results from the HALT-C trial", 《JOURNAL OF HEPATOLOGY》 * |
| YASUHITO TANAKA ET AL.: "Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C", 《NATURE GENETICS》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102816838A (zh) * | 2012-07-06 | 2012-12-12 | 吉林艾迪康医学检验所有限公司 | 用于检测丙型肝炎患者il28b snp12980275多态性的试剂盒 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5727694B2 (ja) | 2015-06-03 |
| WO2011021508A1 (ja) | 2011-02-24 |
| JP2011041526A (ja) | 2011-03-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102482664A (zh) | 用于预测c型肝炎的治疗效果的标记物和预测c型肝炎的治疗效果的方法以及c型肝炎的预防或治疗剂 | |
| CN104630374A (zh) | 与类风湿关节炎相关的单个基因单核苷酸多态性位点及其应用 | |
| CA2460215A1 (en) | Haplotype map of the human genome and uses therefor | |
| CN109504763A (zh) | 用于预测α干扰素治疗乙肝患者疗效的分子标记 | |
| CN114921542A (zh) | 一种与病毒性肝炎抗病毒治疗应答预测相关的snp分子标记及其应用 | |
| JP4295955B2 (ja) | インターフェロンαレセプター2型遺伝子の多型およびその使用 | |
| KR101100437B1 (ko) | 단일염기 다형을 포함하는 대장암과 관련된 폴리뉴클레오티드, 그를 포함하는 마이크로어레이 및 진단 키트 및 그를 이용한 대장암의 진단방법 | |
| CN117844916A (zh) | 识别阿尔茨海默病高危人群的多基因遗传风险分数模型 | |
| JP5787337B2 (ja) | C型肝炎の治療効果を予測するためのマーカー群、検査方法及び検査用キット | |
| JP4197623B2 (ja) | インターフェロンの治療効果を予測するための新規多型マーカー、プライマー、プローブおよびインターフェロンの治療効果を予測する方法 | |
| CN103882112B (zh) | 一种预测强直性脊柱炎易感性的试剂及方法 | |
| CN103060330B (zh) | 一种预测前列腺癌易感性的试剂盒 | |
| CN110592236B (zh) | TNFSF11基因rs9525641 SNP的应用 | |
| JP6245796B2 (ja) | 原発性胆汁性肝硬変の発症リスク予測マーカー、プローブ、プライマー及びキット並びに原発性胆汁性肝硬変の発症リスク予測方法 | |
| CN110484658B (zh) | TNFRSF13B基因rs34562254 SNP的应用 | |
| KR100695147B1 (ko) | 다중좌 마커를 이용한 2형 당뇨병의 진단방법, 2형당뇨병과 연관된 마커를 포함하는 폴리뉴클레오티드 및마이크로어레이 | |
| CN103695549A (zh) | 预测强直性脊柱炎易感性的试剂 | |
| CN103060329B (zh) | 一种预测前列腺癌易感性的检测试剂和方法 | |
| CN103060433B (zh) | 一种预测前列腺癌易感性的试剂盒和方法 | |
| KR101071081B1 (ko) | Defa4 유전자로부터 유래된 단일염기다형을 포함하는 폴리뉴클레오티드, 이를 포함하는 마이크로어레이 및 진단키트, 이를 이용한 검출 방법 | |
| KR20130100640A (ko) | 복부비만 예측용 snp 마커 및 이의 용도 | |
| JP5070552B2 (ja) | C型慢性肝炎治療効果予測のための検査方法及び検査用キット | |
| KR100803258B1 (ko) | 단일염기다형을 포함하는 폴리뉴클레오티드, 그를 포함하는마이크로어레이 및 진단키트, 그를 이용한 b형 간염백신에 대한 항체-무반응 진단방법 | |
| CN103710446B (zh) | 预测强直性脊柱炎易感性的试剂和方法 | |
| Chai et al. | Genetic polymorphisms and periodontitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20120530 |