CN102307941A - 基于磷酸四钙的有机磷组合物和方法 - Google Patents

基于磷酸四钙的有机磷组合物和方法 Download PDF

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Publication number
CN102307941A
CN102307941A CN2009801543835A CN200980154383A CN102307941A CN 102307941 A CN102307941 A CN 102307941A CN 2009801543835 A CN2009801543835 A CN 2009801543835A CN 200980154383 A CN200980154383 A CN 200980154383A CN 102307941 A CN102307941 A CN 102307941A
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CN
China
Prior art keywords
composition
bone
compound
additive
tetracalcium phosphate
Prior art date
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Pending
Application number
CN2009801543835A
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English (en)
Chinese (zh)
Inventor
V·R·嘉利家帕蒂
B·J·赫斯
J·哈拉
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Howmedica Osteonics Corp
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Stryker Development LLC
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Filing date
Publication date
Application filed by Stryker Development LLC filed Critical Stryker Development LLC
Publication of CN102307941A publication Critical patent/CN102307941A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1748—Keratin; Cytokeratin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Transplantation (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials For Medical Uses (AREA)
CN2009801543835A 2008-11-12 2009-11-12 基于磷酸四钙的有机磷组合物和方法 Pending CN102307941A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US19893808P 2008-11-12 2008-11-12
US61/198,938 2008-11-12
US26893109P 2009-06-18 2009-06-18
US61/268,931 2009-06-18
US23776209P 2009-08-28 2009-08-28
US61/237,762 2009-08-28
PCT/US2009/064135 WO2010056811A1 (fr) 2008-11-12 2009-11-12 Compositions organophosphorées à base de phosphate tétracalcique et procédés d'utilisation de celles-ci

Publications (1)

Publication Number Publication Date
CN102307941A true CN102307941A (zh) 2012-01-04

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801543835A Pending CN102307941A (zh) 2008-11-12 2009-11-12 基于磷酸四钙的有机磷组合物和方法

Country Status (11)

Country Link
US (2) US8232327B2 (fr)
EP (1) EP2365994B1 (fr)
JP (1) JP2012508614A (fr)
KR (1) KR101769805B1 (fr)
CN (1) CN102307941A (fr)
AU (1) AU2009314106A1 (fr)
CA (1) CA2743312A1 (fr)
DK (1) DK2365994T3 (fr)
ES (1) ES2616857T3 (fr)
TW (1) TWI501793B (fr)
WO (1) WO2010056811A1 (fr)

Cited By (6)

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CN108025107A (zh) * 2015-05-29 2018-05-11 朗克帕德医疗有限责任公司 用于粘着到表面的组合物及方法
CN109219421A (zh) * 2016-01-12 2019-01-15 朗克帕德医疗有限责任公司 装置和组合物及其使用方法
CN110062635A (zh) * 2016-09-27 2019-07-26 Gp生物有限公司 α-TCP、硅酸盐和磷酸化氨基酸的组合物
US11247941B2 (en) 2016-08-08 2022-02-15 RevBio, Inc. Compositions and methods for adhesion to surfaces
CN114917397A (zh) * 2022-06-13 2022-08-19 北京纳通医学研究院有限公司 一种骨粘合剂的固相组合物及骨粘合剂
CN115804861A (zh) * 2021-09-14 2023-03-17 北京纳通医学研究院有限公司 一种骨粘合剂固相组合物及骨粘合剂

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KR101769805B1 (ko) 2017-08-21
TW201029680A (en) 2010-08-16
JP2012508614A (ja) 2012-04-12
EP2365994B1 (fr) 2017-01-04
US20100121459A1 (en) 2010-05-13
TWI501793B (zh) 2015-10-01
DK2365994T3 (en) 2017-03-27
AU2009314106A1 (en) 2010-05-20
KR20110104488A (ko) 2011-09-22
WO2010056811A1 (fr) 2010-05-20
EP2365994A1 (fr) 2011-09-21
US8232327B2 (en) 2012-07-31
ES2616857T3 (es) 2017-06-14
US8273803B2 (en) 2012-09-25

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