CN102302161B - Preparation method of ophidine oral liquid - Google Patents
Preparation method of ophidine oral liquid Download PDFInfo
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- CN102302161B CN102302161B CN201110272308.8A CN201110272308A CN102302161B CN 102302161 B CN102302161 B CN 102302161B CN 201110272308 A CN201110272308 A CN 201110272308A CN 102302161 B CN102302161 B CN 102302161B
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Abstract
The invention relates to a preparation method of ophidine oral liquid. The preparation method is characterized by adopting the following technical scheme: (1) slaughtering adult healthy black-tail snake and pit viper used as raw materials, removing heads and tails, removing skin and viscera, cleaning, mincing, pulping, breaking cell walls, regulating concentration, heating, performing enzymolysis, deactivating enzyme, and performing centrifugal filtration, ultrafiltration membrane filtration and other procedures to obtain enzymatic hydrolysate for later use; (2) compounding Chinese yam, Chinese wolfberry, Poria cocos, Chinese dates, kudzu roots, lotus seeds, Gordon euryale seeds, polygonatum, cassia barks, licorice roots and other raw materials, cleaning, soaking, decocting, filtering, and performing other procedures to obtain traditional Chinese medicinal solution for later use; and (3) compounding the liquid obtained in steps (1) and (2) with adjuvants, adjusting concentration, filling, sterilizing, inspecting, and packaging to obtain finished products. The molecular weight of 80-90% of the enzymatic hydrolysate obtained using the technical scheme provided by the invention distributes in a range of 200-5000 Daltons, and the enzymatic hydrolysate contains docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and other nutritional ingredients.
Description
Technical field
The present invention relates to a kind of method utilizing the technology processing and manufacturing ophidine oral liquid of biology enzyme enzymolysis protein matter.Belong to functional food manufacture field.
Background technology
Zaocys dhumnade and pallas pit viper are all animals that dietotherapeutic nutritive value is very high.Record according to Compendium of Material Medica: enter liver, spleen two warp, inside walk internal organs, outer thorough skin.Modern medicine study proves, meat of snake contains 18 seed amino acids (wherein human body can not synthesize and 8 required seed amino acids account for significant proportion), and the amino acids distribution of meat of snake albumen and the amino acids distribution of human body protein are closely.Among the people be widely used in keep fit strong bone, tender skin beauty treatment, go to wrinkle except the taking good care of of spot, after being ill body void.
But the protein molecule of meat of snake is very large, and the digestive system of human body is difficult to digested and assimilated and effectively utilize.The snake series products process technology that the present patent document that can see is introduced is nearly all adopt fairly simple physical refining processes.For this high protein diet of meat of snake, the physical method of drying and crushing fundamentally can not change the characteristic of protein macromolecule, and the activity of product is low, and absorptivity is low, poorly soluble, and therefore the range of application of product is subject to drastic delimitations.
The method of bio-enzyme degradation, can make macromolecular protein become small-molecular peptides, and its biologically active is strengthened greatly, and no antigen, can not allergic reaction be produced; Dissolubility, stability improve all greatly, and the processing characteristics of product is improved.Small-molecular peptides also has the feature faster than Amino Acid Absorption speed, absorption efficiency is higher.At present, biological enzymolysis technology has become the mainstream technology of biologically active peptide and protein hydrolysate product research and development and application.In recent years, snake class is more and more subject to people's attention as important food resource and drug resource and active development utilizes, and becomes the focus of scientific research and new product development.
In the research and development of snake series products, have no the report studied and manufacture new product that to be combined with modern biotechnology by Chinese Traditional Medicine.Biological enzyme technology fundamentally can solve the difficult problem that protein macromolecule is difficult to fully be digested and assimilated by human body, and the meat of snake active peptide that enzymolysis obtains has the health-care efficacy of highly significant; The tonifying Qi of Traditional Chinese Medicine, principle of enriching blood, can have complementary advantages, bring out the best in each other with effect of ophidine.The many-side that we carry out in the process of innovation and creation is explored, and achieves gratifying progress.Ophidine all shows good effect in develop immunitypty, antifatigue, recovery cardiovascular and cerebrovascular elasticity, improving water flood, beautifying face and moistering lotion etc.
Summary of the invention
The present invention relates to a kind of manufacture method of ophidine oral liquid.It is characterized in that adopting following technical scheme:
1, select adult healthy zaocys dhumnade, pallas pit viper live body is raw material, through slaughtering, removing end to end, remove skin and internal organ, cleaning, rubbing, slurrying, broken wall, adjustment concentration, heat, enzymolysis, the enzyme that goes out, centrifugal filtration, the operation such as ultrafiltration membrance filter, make enzymolysis liquid stand-by;
2, select the raw materials such as Chinese yam, matrimony vine, Poria cocos, date, the root of kudzu vine, lotus seeds, Gorgon fruit, sealwort, Chinese cassia tree, Radix Glycyrrhizae, through operations such as mixture, cleaning, immersion, fried, filtrations, make herb liquid stand-by;
3,1,2 step gained liquid are added auxiliary material mixture, adjustment concentration, filling, sterilizing, inspection, packaging get product.
The enzymolysis liquid molecular weight 80%-90% using the technical program to obtain is distributed between 200-5000Dalton, containing nutritional labelings such as DHA (DHA) and eicosapentaenoic acids (EPA).
Embodiment 1
Get Carnis Zaocys 4--6 kilogram, cleaning, rubbing, slurrying, broken wall, mix thoroughly with drinking water 10 kilograms, heat to 35 DEG C-60 DEG C, enzymolysis 3-4 hour, 90 DEG C of enzymes 10 minutes that go out, centrifugal filtration, ultrafiltration membrance filter, gained enzymolysis liquid is concentrated into 7-8 kilogram stand-by.
Get Chinese yam 2.4 kilograms, matrimony vine 2.2 kilograms, 1.6 kilograms, Poria cocos, 1.8 kilograms, date, the root of kudzu vine 1.8 kilograms, 1.6 kilograms, lotus seeds, Gorgon fruit 1.2 kilograms, sealwort 0.8 kilogram, Chinese cassia tree 0.8 kilogram, 0.8 kilogram, Radix Glycyrrhizae clean, soak 2 hours with drinking water 60 kilograms, then 15 minutes are boiled, 90 DEG C are incubated 3 hours, filter and remove residue, gained Chinese medicinal liquid concentrating is stand-by to 8-9 kilogram.
By above-mentioned two kinds of stand-by liquid mixtures, add honey 1-2 kilogram, isomaltoketose 0.1-0.5 kilogram, burnt sugar coloring 0.01-0.05 kilogram, adding distil water to 2 ten thousand milliliters, filter, filtrate is distributed into 20 milliliters/bottle, totally 1000 bottles, 110 DEG C of sterilizings 20 minutes, inspection, packaging, storage.
Embodiment 2
Get pallas pit viper meat 3--5 kilogram, cleaning, rubbing, slurrying, broken wall, mix thoroughly with drinking water 8 kilograms, heat to 45 DEG C-65 DEG C, enzymolysis 3-4 hour, 90 DEG C of enzymes 10 minutes that go out, centrifugal filtration, ultrafiltration membrance filter, gained enzymolysis liquid is concentrated into 7-8 kilogram stand-by.
Get Chinese yam 2.2 kilograms, matrimony vine 2.0 kilograms, 1.4 kilograms, Poria cocos, 1.6 kilograms, date, the root of kudzu vine 1.6 kilograms, 1.4 kilograms, lotus seeds, Gorgon fruit 1.2 kilograms, sealwort 0.8 kilogram, Chinese cassia tree 0.8 kilogram, 0.8 kilogram, Radix Glycyrrhizae clean, soak 2 hours with drinking water 50 kilograms, then 20 minutes are boiled, 95 DEG C are incubated 4 hours, filter and remove residue, gained Chinese medicinal liquid concentrating is stand-by to 8-9 kilogram.
By above-mentioned two kinds of stand-by liquid mixtures, add honey 1-2 kilogram, isomaltoketose 0.1-0.5 kilogram, burnt sugar coloring 0.01-0.05 kilogram, adding distil water to 2 ten thousand milliliters, filter, filtrate is distributed into 20 milliliters/bottle, totally 1000 bottles, 110 DEG C of sterilizings 20 minutes, inspection, packaging, storage.
Embodiment 3
Get each 3 kilograms of Carnis Zaocys, pallas pit viper meat, cleaning, rubbing, slurrying, broken wall, mix thoroughly with drinking water 10 kilograms, heat to 35 DEG C-60 DEG C, enzymolysis 3-4 hour, 90 DEG C of enzymes 10 minutes that go out, centrifugal filtration, ultrafiltration membrance filter, gained enzymolysis liquid is concentrated into 7-8 kilogram stand-by.
Get Chinese yam 2.4 kilograms, matrimony vine 2.2 kilograms, 1.6 kilograms, Poria cocos, 1.6 kilograms, date, the root of kudzu vine 1.8 kilograms, 1.6 kilograms, lotus seeds, Gorgon fruit 1.2 kilograms, sealwort 0.8 kilogram, Chinese cassia tree 0.8 kilogram, 0.6 kilogram, Radix Glycyrrhizae clean, soak 2 hours with drinking water 60 kilograms, then 15 minutes are boiled, 90 DEG C are incubated 3 hours, filter and remove residue, gained Chinese medicinal liquid concentrating is stand-by to 8-9 kilogram.
By above-mentioned two kinds of stand-by liquid mixtures, add honey 1-2 kilogram, isomaltoketose 0.1-0.5 kilogram, burnt sugar coloring 0.01-0.05 kilogram, adding distil water to 2 ten thousand milliliters, filter, filtrate is distributed into 20 milliliters/bottle, totally 1000 bottles, 110 DEG C of sterilizings 20 minutes, inspection, packaging, storage.
Claims (2)
1. a manufacture method for ophidine oral liquid, is characterized in that manufacture method is as follows:
A. select adult healthy zaocys dhumnade, the live body of pallas pit viper is raw material, through slaughtering, removing end to end, remove skin and internal organ, cleaning, rubbing, slurrying, broken wall, adjustment concentration, heat, enzymolysis, the enzyme that goes out, centrifugal filtration, ultrafiltration membrance filter operation, make enzymolysis liquid stand-by;
B. select Chinese yam, matrimony vine, Poria cocos, date, the root of kudzu vine, lotus seeds, Gorgon fruit, sealwort, Chinese cassia tree, Radix Glycyrrhizae to be raw material, through mixture, cleaning, immersion, fried, filter progress, make herb liquid stand-by;
C. A, step B gained liquid are added auxiliary material mixture, adjustment concentration, filling, sterilizing, inspection, packaging get product.
2. the manufacture method of ophidine oral liquid according to claim 1, it is characterized in that gained enzymolysis liquid molecular weight 80%-90% is distributed between 200-5000 Dalton, containing DHA (DHA) and eicosapentaenoic acid (EPA) nutritional labeling; Described ophidine oral liquid is a kind of health beverages.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110272308.8A CN102302161B (en) | 2011-09-02 | 2011-09-02 | Preparation method of ophidine oral liquid |
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| CN201110272308.8A CN102302161B (en) | 2011-09-02 | 2011-09-02 | Preparation method of ophidine oral liquid |
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| CN102302161A CN102302161A (en) | 2012-01-04 |
| CN102302161B true CN102302161B (en) | 2015-03-25 |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102719345A (en) * | 2012-06-28 | 2012-10-10 | 唐作安 | Production method of snake peptide wine |
| CN103230073B (en) * | 2013-05-10 | 2014-03-19 | 王志美 | Snake juice drink |
| CN104799389A (en) * | 2014-01-23 | 2015-07-29 | 河南省永传医药科技有限公司 | Agkistrodon halys-papaya solid beverage |
| CN105767915A (en) * | 2016-03-22 | 2016-07-20 | 山东海波海洋生物科技股份有限公司 | Flavored snake-meat food and preparation method thereof |
| CN105795359A (en) * | 2016-04-07 | 2016-07-27 | 山东海波海洋生物科技股份有限公司 | Mixed snake powder food and preparation method thereof |
| CN107693575A (en) * | 2017-11-02 | 2018-02-16 | 林峰 | Chinese medicine composition of the peptide containing zaocys dhumnade with dispelling wind and removing obstruction in the meridians effect and its production and use |
| CN111955681A (en) * | 2020-08-31 | 2020-11-20 | 烟台菊福堂生物科技有限公司 | Instant sea cucumber, oyster and snake meat oral liquid and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1191116A (en) * | 1997-02-19 | 1998-08-26 | 方晓阳 | Oral snake liquid |
| CN1327798A (en) * | 2001-06-28 | 2001-12-26 | 永州异蛇生物科技有限公司 | Process for preparing low-peptide mixer by controlled enzymolysis of snake |
| CN1569123A (en) * | 2004-04-30 | 2005-01-26 | 成进学 | Oral functional Chinese medicine intensified by snake, bee, macroelement and microelement and its preparation |
| CN101972423B (en) * | 2010-10-09 | 2011-11-23 | 何龙 | Black-snake beautifying oral liquid |
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