CN1019911C - 新的苯并嗪衍生物的制备方法 - Google Patents

新的苯并嗪衍生物的制备方法 Download PDF

Info

Publication number
CN1019911C
CN1019911C CN88101541A CN88101541A CN1019911C CN 1019911 C CN1019911 C CN 1019911C CN 88101541 A CN88101541 A CN 88101541A CN 88101541 A CN88101541 A CN 88101541A CN 1019911 C CN1019911 C CN 1019911C
Authority
CN
China
Prior art keywords
salts
compound
molecular formula
defined above
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN88101541A
Other languages
English (en)
Chinese (zh)
Other versions
CN88101541A (zh
Inventor
饭岛郁夫
大关正胜
奥村邦人
稻益正德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of CN88101541A publication Critical patent/CN88101541A/zh
Application granted granted Critical
Publication of CN1019911C publication Critical patent/CN1019911C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN88101541A 1987-03-18 1988-03-17 新的苯并嗪衍生物的制备方法 Expired - Fee Related CN1019911C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP65360/87 1987-03-18
JP62065360A JPS63230689A (ja) 1987-03-18 1987-03-18 ベンゾオキサジン誘導体

Publications (2)

Publication Number Publication Date
CN88101541A CN88101541A (zh) 1988-10-05
CN1019911C true CN1019911C (zh) 1993-02-17

Family

ID=13284716

Family Applications (1)

Application Number Title Priority Date Filing Date
CN88101541A Expired - Fee Related CN1019911C (zh) 1987-03-18 1988-03-17 新的苯并嗪衍生物的制备方法

Country Status (16)

Country Link
US (1) US4824833A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0283036B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS63230689A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR940003071B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1019911C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE67199T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1305706C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3864707D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK147588A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2038710T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI91870C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2612517B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3002692T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (2) HU203548B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE60522B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL85768A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018805A1 (en) * 1992-09-21 1995-07-13 Senju Pharmaceutical Co., Ltd. 1,4-benzoxazine-2-acetic acid compound, process for producing the same, and use thereof
US5332733A (en) * 1990-11-24 1994-07-26 Kali-Chemie Pharma Gmbh Heterocyclically substituted piperazinoakylbenzoxazine and piperazinoalkylbenzothiazine compounds, processes for preparing them, and medicaments containing them
US5635505A (en) * 1994-01-06 1997-06-03 Senju Pharmaceutical Co., Ltd. 1,4-benzoxazine-2-acetic acid compound, method for production thereof and use thereof
CA2384194A1 (en) 1999-08-31 2001-03-08 David P. M. Pleynet Benzylidene-thiazolidinediones and analogues and their use in the treatment of inflammation
CA2473156A1 (en) * 2001-03-08 2002-09-19 Incyte San Diego, Inc. Rxr activating molecules
US7102000B2 (en) * 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
EP1549644A1 (en) 2002-07-10 2005-07-06 Applied Research Systems ARS Holding N.V. Azolidinone-vinyl fused-benzene derivatives
BR0316386A (pt) * 2002-12-06 2005-09-27 Warner Lambert Co Benzoxazin-3-onas e seus derivados como inibidores de p13k
ES2393197T3 (es) * 2004-09-28 2012-12-19 Otsuka Pharmaceutical Co., Ltd. Compuesto de carbostirilo
CN100455573C (zh) * 2005-11-11 2009-01-28 华东理工大学 一种制备1,4-苯并噁唑嗪-3-酮化合物的微波合成方法
CA2898482A1 (en) * 2013-02-22 2014-08-28 Linda L. Brockunier Antidiabetic bicyclic compounds
US10968193B2 (en) 2014-08-08 2021-04-06 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
US4619687A (en) * 1984-09-27 1986-10-28 Sumitomo Chemical Company, Limited Triazolopyridazines and their use as herbicides
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
WO1986007056A1 (en) * 1985-05-21 1986-12-04 Pfizer Inc. Hypoglycemic thiazolidinediones
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
JPS6314782A (ja) * 1986-07-07 1988-01-21 Nippon Tokushu Noyaku Seizo Kk 新規ジアルキルマレインイミド類及び除草剤
US4734124A (en) * 1987-01-15 1988-03-29 Fmc Corporation Tetrazolinone herbicides
FI91869C (fi) * 1987-03-18 1994-08-25 Tanabe Seiyaku Co Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi

Also Published As

Publication number Publication date
EP0283036A1 (en) 1988-09-21
KR940003071B1 (ko) 1994-04-13
FI91870C (fi) 1994-08-25
DK147588A (da) 1988-09-19
ATE67199T1 (de) 1991-09-15
HUT50337A (en) 1990-01-29
IL85768A0 (en) 1988-09-30
IL85768A (en) 1993-02-21
HU211596A9 (en) 1995-12-28
DK147588D0 (da) 1988-03-17
ES2038710T3 (es) 1993-08-01
CN88101541A (zh) 1988-10-05
FI881104L (fi) 1988-09-19
JPH0460597B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-09-28
HU203548B (en) 1991-08-28
CA1305706C (en) 1992-07-28
KR880011154A (ko) 1988-10-26
DE3864707D1 (de) 1991-10-17
GR3002692T3 (en) 1993-01-25
IE60522B1 (en) 1994-07-27
FI91870B (fi) 1994-05-13
FR2612517B1 (fr) 1992-11-13
IE880772L (en) 1988-09-18
AU1317688A (en) 1988-09-22
FR2612517A1 (fr) 1988-09-23
EP0283036B1 (en) 1991-09-11
US4824833A (en) 1989-04-25
FI881104A0 (fi) 1988-03-09
JPS63230689A (ja) 1988-09-27
AU601029B2 (en) 1990-08-30

Similar Documents

Publication Publication Date Title
CN1026322C (zh) 苯并哑唑衍生物的制备方法
CN1069901C (zh) N-苄基二氧代噻唑烷基苯甲酰胺衍生物及其制造方法
CN1065863C (zh) N-取代二氧代噻唑烷基苯甲酰胺衍生物及其制备方法
CN1019911C (zh) 新的苯并嗪衍生物的制备方法
CN1075811C (zh) 新型取代的2,4-噻唑烷二酮衍生物,其制备方法以及含有它们的药物组合物
CN86100411A (zh) 生产噻唑烷二酮的方法
JPS6154792B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN1208335C (zh) 噻唑烷二酮衍生物及其作为抗糖尿病药的用途
CN1285831A (zh) 取代的噻唑烷二酮衍生物,其制备过程及其药学用途
CN87104099A (zh) 抗变态反应和消炎药剂
CN1015627B (zh) 芳香基呱嗪基-亚烷基苯基-杂环化合物的制备方法
US7777037B2 (en) Ziprasidone process
HK1043117A1 (en) Polycyclic 2-amino-thiazole systems, method for the production thereof and medicament containing said compounds
CN87105612A (zh) 嘧啶衍生物
CN1149205C (zh) 多环的噻唑体系和它们作为减食欲剂的用途
CN1875018A (zh) 制备噻唑烷二酮的方法
CN87103808A (zh) 多巴胺-β-羟化酶抑制剂
CN1019196B (zh) 2-噻唑烷酮类衍生物的制备方法
CN1107844A (zh) 二氢化茚衍生物和其制法及合成该衍生物的中间体
JPH0460584B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN1052480A (zh) 新的噻唑烷酮衍生物含有这些衍生物的药物组合物及其制备方法
CN1112925A (zh) 咪唑吡啶衍生物及其制备方法
CN1114835A (zh) 膦酸二酯衍生物
CN1032009A (zh) 脲的衍生物
CN87104206A (zh) 安息香酸衍生物及其制造方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee