CN101969953B - 用于治疗bh4反应性疾病的喋呤类似物 - Google Patents

用于治疗bh4反应性疾病的喋呤类似物 Download PDF

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CN101969953B
CN101969953B CN2008801242617A CN200880124261A CN101969953B CN 101969953 B CN101969953 B CN 101969953B CN 2008801242617 A CN2008801242617 A CN 2008801242617A CN 200880124261 A CN200880124261 A CN 200880124261A CN 101969953 B CN101969953 B CN 101969953B
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disease
acid
alkenylene
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alkylene
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CN101969953A (zh
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E·D·卡基斯
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Biomarin Pharmaceutical Inc
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CN2008801242617A 2008-01-03 2008-07-07 用于治疗bh4反应性疾病的喋呤类似物 Expired - Fee Related CN101969953B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1873508P 2008-01-03 2008-01-03
US61/018,735 2008-01-03
US1975308P 2008-01-08 2008-01-08
US61/019,753 2008-01-08
PCT/US2008/069319 WO2009088530A1 (en) 2008-01-03 2008-07-07 Pterin analog for treating bh4 responsive condition

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CN101969953A CN101969953A (zh) 2011-02-09
CN101969953B true CN101969953B (zh) 2013-01-09

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US (2) US7601717B2 (enExample)
EP (1) EP2224927B1 (enExample)
JP (1) JP2011508775A (enExample)
CN (1) CN101969953B (enExample)
AU (1) AU2008347005B2 (enExample)
BR (1) BRPI0821970A2 (enExample)
CA (1) CA2711160A1 (enExample)
ES (1) ES2524026T3 (enExample)
MX (1) MX2010006025A (enExample)
RU (1) RU2470642C2 (enExample)
WO (1) WO2009088530A1 (enExample)

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CA2675134A1 (en) * 2007-01-12 2008-07-24 Biomarin Pharmaceutical Inc. Pterin analogs
JP5066756B2 (ja) * 2010-04-22 2012-11-07 学校法人日本大学 脳機能障害予防・改善用の薬剤及び飲食物
US20130338176A1 (en) * 2010-10-29 2013-12-19 The Trustees Of Columbia University In The City Of New York Methods of preventing and treating hyperlipidemia or atherosclerosis
WO2013055954A1 (en) * 2011-10-11 2013-04-18 The Regents Of The University Of California Biomarker for abdominal aortic aneurysm
SG10201606063RA (en) 2012-01-23 2016-09-29 Sage Therapeutics Inc Neuroactive steroid formulations and methods of treating cns disorders
RS62761B1 (sr) 2012-08-21 2022-01-31 Sage Therapeutics Inc Alopregnanolon za lečenje refraktornog epileptičkog statusa
DK2919780T3 (en) 2012-11-14 2018-11-26 Bial Portela & Ca Sa 1,3-Dihydroimidazole-2-thione derivatives for use in the treatment of pulmonary arterial hypertension and lung injury
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
AU2015374379B2 (en) * 2014-12-30 2018-10-04 Dow Agrosciences Llc Picolinamides as fungicides
PH12018501923B1 (en) 2016-03-08 2024-06-28 Sage Therapeutics Inc Neuroactive steroids, compositions, and uses thereof
KR20190138683A (ko) * 2017-04-21 2019-12-13 스티븐 호프만 망막병증을 치료하기 위한 조성물 및 방법
WO2019067782A1 (en) * 2017-09-28 2019-04-04 University Of Massachusetts COMBINED TREATMENT OF NEUROPSYCHIATRIC DISORDERS
WO2019175332A1 (en) 2018-03-14 2019-09-19 Imba - Institut Für Molekulare Biotechnologie Gmbh Bh4 pathway inhibition and use thereof for treating t-cell mediated autoimmune diseases or hypersensitivity
WO2019175328A1 (en) 2018-03-14 2019-09-19 Imba - Institut Für Molekulare Biotechnologie Gmbh Bh4pathwayactivationandusethereoffortreatingcancer
JP7553906B2 (ja) * 2018-11-01 2024-09-19 宏 一瀬 Ｓｐｒをコードするポリヌクレオチドを含む組換えベクター、及びそれを含む組成物
CN112394178B (zh) * 2020-11-16 2022-08-05 首都医科大学附属北京朝阳医院 莫西沙星相关肝损伤的生物标志物、试剂盒及应用

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JP2011508775A (ja) 2011-03-17
CN101969953A (zh) 2011-02-09
EP2224927B1 (en) 2014-08-20
WO2009088530A1 (en) 2009-07-16
US8324210B2 (en) 2012-12-04
EP2224927A1 (en) 2010-09-08
ES2524026T3 (es) 2014-12-03
US7601717B2 (en) 2009-10-13
RU2010132278A (ru) 2012-02-10
US20090176790A1 (en) 2009-07-09
RU2470642C2 (ru) 2012-12-27
CA2711160A1 (en) 2009-07-16
MX2010006025A (es) 2010-06-30
US20100093742A1 (en) 2010-04-15
BRPI0821970A2 (pt) 2015-06-23
AU2008347005B2 (en) 2013-10-03
AU2008347005A1 (en) 2009-07-16

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