CN101874031B - 瑟土因调节性咪唑并噻唑化合物 - Google Patents

瑟土因调节性咪唑并噻唑化合物 Download PDF

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CN101874031B
CN101874031B CN2008801034489A CN200880103448A CN101874031B CN 101874031 B CN101874031 B CN 101874031B CN 2008801034489 A CN2008801034489 A CN 2008801034489A CN 200880103448 A CN200880103448 A CN 200880103448A CN 101874031 B CN101874031 B CN 101874031B
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plucked instrument
compound
instrument soil
ylmethyl
protein
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CN101874031A (zh
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琼·贝米斯
杰里米·S·迪施
迈克尔·杰劳塞克
沃尔特·J·伦斯曼
P·Y·吴
奇·B·武
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Sirtris Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
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    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • Heart & Thoracic Surgery (AREA)
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  • Neurosurgery (AREA)
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  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
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  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN2008801034489A 2007-06-20 2008-06-20 瑟土因调节性咪唑并噻唑化合物 Expired - Fee Related CN101874031B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93663307P 2007-06-20 2007-06-20
US60/936,633 2007-06-20
PCT/US2008/007771 WO2008156866A1 (en) 2007-06-20 2008-06-20 Sirtuin modulating imidazothiazole compounds

Publications (2)

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CN101874031A CN101874031A (zh) 2010-10-27
CN101874031B true CN101874031B (zh) 2013-02-20

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US (2) US7829556B2 (https=)
EP (1) EP2167510B1 (https=)
JP (1) JP5281081B2 (https=)
KR (1) KR101525268B1 (https=)
CN (1) CN101874031B (https=)
AR (1) AR067106A1 (https=)
AU (1) AU2008266746B2 (https=)
BR (1) BRPI0813653A2 (https=)
CA (1) CA2692099C (https=)
CL (1) CL2008001821A1 (https=)
CO (1) CO6261382A2 (https=)
CR (1) CR11231A (https=)
DO (1) DOP2009000283A (https=)
EA (1) EA018182B1 (https=)
ES (1) ES2534544T3 (https=)
IL (1) IL202729A (https=)
MA (1) MA31568B1 (https=)
MX (1) MX2009013976A (https=)
MY (1) MY149316A (https=)
NZ (1) NZ581989A (https=)
PE (1) PE20090423A1 (https=)
TW (1) TW200918542A (https=)
UA (1) UA104127C2 (https=)
UY (1) UY31170A1 (https=)
WO (1) WO2008156866A1 (https=)
ZA (1) ZA200908882B (https=)

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