CN101668865B - 与心血管疾病相关联的遗传易感性变体 - Google Patents

与心血管疾病相关联的遗传易感性变体 Download PDF

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CN101668865B
CN101668865B CN200880011908.5A CN200880011908A CN101668865B CN 101668865 B CN101668865 B CN 101668865B CN 200880011908 A CN200880011908 A CN 200880011908A CN 101668865 B CN101668865 B CN 101668865B
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allele
risk
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cardiovascular disease
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CN101668865A (zh
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安娜·海尔格多蒂尔
古德玛尔·索尔莱夫松
安德烈·马诺列斯库
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Decode Genetics ehf
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN200880011908.5A 2007-02-21 2008-02-21 与心血管疾病相关联的遗传易感性变体 Expired - Fee Related CN101668865B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
IS8613 2007-02-21
IS8613 2007-02-21
IS8640 2007-04-30
IS8640 2007-04-30
IS8701 2007-12-21
IS8701 2007-12-21
PCT/IS2008/000007 WO2008102380A1 (en) 2007-02-21 2008-02-21 Genetic susceptibility variants associated with cardiovascular disease

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CN101668865A CN101668865A (zh) 2010-03-10
CN101668865B true CN101668865B (zh) 2015-05-06

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JP (1) JP5646179B2 (enExample)
KR (1) KR101571523B1 (enExample)
CN (1) CN101668865B (enExample)
AU (1) AU2008218542B2 (enExample)
BR (1) BRPI0807927A2 (enExample)
CA (1) CA2679581C (enExample)
DK (1) DK2471954T3 (enExample)
EA (1) EA022610B1 (enExample)
HU (1) HUE030996T2 (enExample)
IL (1) IL200453A (enExample)
MX (1) MX2009008878A (enExample)
NZ (1) NZ579445A (enExample)
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CN104946731B (zh) * 2014-03-28 2019-12-20 中国中医科学院中药研究所 快速检测金银花的pcr试剂盒及检测方法
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CN106811520A (zh) * 2016-08-17 2017-06-09 上海易瑞生物科技有限公司 一种心肌梗死易感基因检测分型试剂盒及其应用
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CN108342472A (zh) * 2018-04-13 2018-07-31 东华大学 一种冠心病易感基因检测分型试剂盒
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CN109486940A (zh) * 2018-12-25 2019-03-19 北京北基医学检验实验室有限公司 一种扩增颅内动脉肿瘤相关基因的引物组及检测试剂盒
CN109628577A (zh) * 2019-01-07 2019-04-16 杭州艾迪康医学检验中心有限公司 检测冠状动脉硬化相关单核苷酸多态性位点的引物和方法
KR102158714B1 (ko) * 2019-04-03 2020-09-22 한림대학교 산학협력단 Tcf24 유전자의 단일염기다형성을 포함하는 뇌동맥류 진단용 snp 마커
KR102158720B1 (ko) * 2019-04-03 2020-09-22 한림대학교 산학협력단 Lrrc3 유전자의 단일염기다형성을 포함하는 뇌동맥류 진단용 snp 마커
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KR102344173B1 (ko) * 2021-05-03 2021-12-29 주식회사 바이오에이지 임상 및 유전변이 정보를 통합한 한국인 관상동맥 질환 예측 방법 및 관련 검사추천방법
KR102366097B1 (ko) * 2021-05-03 2022-02-23 주식회사 바이오에이지 임상 및 유전변이 정보를 통합한 한국인 뇌혈관 질환 예측 방법 및 관련 검사추천방법
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KR101571523B1 (ko) 2015-11-24
AU2008218542B2 (en) 2014-06-26
CN101668865A (zh) 2010-03-10
NZ579445A (en) 2012-02-24
JP2010518848A (ja) 2010-06-03
EP2471954A1 (en) 2012-07-04
KR20090117896A (ko) 2009-11-13
JP5646179B2 (ja) 2014-12-24
DK2471954T3 (en) 2016-09-12
US20100068705A1 (en) 2010-03-18
CA2679581A1 (en) 2008-08-28
US20120208709A1 (en) 2012-08-16
IL200453A0 (en) 2010-04-29
CA2679581C (en) 2020-12-22
BRPI0807927A2 (pt) 2014-06-24
EP2471954B1 (en) 2016-08-24
EA022610B1 (ru) 2016-02-29
SG178811A1 (en) 2012-03-29
IL200453A (en) 2014-12-31
AU2008218542A1 (en) 2008-08-28
WO2008102380A1 (en) 2008-08-28
HUE030996T2 (en) 2017-06-28
EA200970781A1 (ru) 2010-04-30
MX2009008878A (es) 2009-08-28
EP2115172A1 (en) 2009-11-11
US9617597B2 (en) 2017-04-11

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