CN101529251B - 用于亲合分析的结合性表面 - Google Patents

用于亲合分析的结合性表面 Download PDF

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Publication number
CN101529251B
CN101529251B CN200780040215.4A CN200780040215A CN101529251B CN 101529251 B CN101529251 B CN 101529251B CN 200780040215 A CN200780040215 A CN 200780040215A CN 101529251 B CN101529251 B CN 101529251B
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China
Prior art keywords
biotin
binding
microparticles
ligand
support
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Expired - Fee Related
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CN200780040215.4A
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English (en)
Chinese (zh)
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CN101529251A (zh
Inventor
乔舒亚·C·索尔多
詹姆斯·L·萨克里森
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Beckman Coulter Inc
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Beckman Instruments Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B20/00Methods specially adapted for identifying library members
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN200780040215.4A 2006-11-01 2007-11-01 用于亲合分析的结合性表面 Expired - Fee Related CN101529251B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86382006P 2006-11-01 2006-11-01
US60/863,820 2006-11-01
PCT/US2007/023033 WO2008057366A2 (en) 2006-11-01 2007-11-01 Binding surfaces for affinity assays

Publications (2)

Publication Number Publication Date
CN101529251A CN101529251A (zh) 2009-09-09
CN101529251B true CN101529251B (zh) 2014-04-02

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CN200780040215.4A Expired - Fee Related CN101529251B (zh) 2006-11-01 2007-11-01 用于亲合分析的结合性表面

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US (2) US20080176340A1 (https=)
EP (1) EP2069790B1 (https=)
JP (1) JP5224477B2 (https=)
KR (1) KR101457716B1 (https=)
CN (1) CN101529251B (https=)
AU (1) AU2007317996B9 (https=)
BR (1) BRPI0718009B1 (https=)
ES (1) ES2537564T3 (https=)
IL (1) IL198490A (https=)
MX (1) MX2009004354A (https=)
WO (1) WO2008057366A2 (https=)

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Also Published As

Publication number Publication date
BRPI0718009A2 (pt) 2013-11-19
JP2010508513A (ja) 2010-03-18
WO2008057366A3 (en) 2008-09-12
WO2008057366A2 (en) 2008-05-15
WO2008057366A8 (en) 2008-07-24
KR20090085596A (ko) 2009-08-07
JP5224477B2 (ja) 2013-07-03
MX2009004354A (es) 2009-06-18
AU2007317996A1 (en) 2008-05-15
EP2069790B1 (en) 2015-04-29
IL198490A (en) 2013-05-30
ES2537564T3 (es) 2015-06-09
CN101529251A (zh) 2009-09-09
KR101457716B1 (ko) 2014-11-03
US20080176340A1 (en) 2008-07-24
US8518714B2 (en) 2013-08-27
AU2007317996B9 (en) 2012-10-18
EP2069790A4 (en) 2009-11-25
US20120077284A1 (en) 2012-03-29
IL198490A0 (en) 2010-02-17
AU2007317996B2 (en) 2012-09-13
HK1129462A1 (en) 2009-11-27
BRPI0718009B1 (pt) 2016-02-16
EP2069790A2 (en) 2009-06-17
AU2007317996A2 (en) 2009-06-18

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