CN101431959A - 钙吸收促进剂 - Google Patents
钙吸收促进剂 Download PDFInfo
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- CN101431959A CN101431959A CNA200780013329XA CN200780013329A CN101431959A CN 101431959 A CN101431959 A CN 101431959A CN A200780013329X A CNA200780013329X A CN A200780013329XA CN 200780013329 A CN200780013329 A CN 200780013329A CN 101431959 A CN101431959 A CN 101431959A
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Abstract
Description
Claims (17)
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US77437406P | 2006-02-17 | 2006-02-17 | |
US60/774,374 | 2006-02-17 | ||
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JP041158/2006 | 2006-02-17 |
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CN (2) | CN102755374A (zh) |
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SG (1) | SG169979A1 (zh) |
TW (1) | TW200800292A (zh) |
WO (1) | WO2007094486A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107929313A (zh) * | 2017-11-21 | 2018-04-20 | 上海金城药业有限公司 | 用于预防和治疗钙缺乏症的天然型牡蛎碳酸钙制剂及其制备方法 |
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DE102007039310A1 (de) * | 2007-08-13 | 2009-02-19 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Zusammensetzung zur Prophylaxe und Behandlung von Osteoporose |
JP2011525356A (ja) * | 2008-06-23 | 2011-09-22 | アマノ エンザイム ユーエスエー,リミテッド | 風味改良の酵素的方法 |
US10092518B2 (en) | 2012-04-10 | 2018-10-09 | Alpina Laudanum Institute Of Phytopharmaceutical Sciences Ag | Wet granulation process and granulate material comprising Arabic gum |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4097601A (en) * | 1977-08-26 | 1978-06-27 | Pfizer Inc. | Bone deposition by 2-descarboxy-2-(tetrazol-5-yl)-11-dexosy-16-aryl prostaglandins |
US5545414A (en) * | 1995-03-22 | 1996-08-13 | Abbott Laboratories | Cholesterol lowering food product |
NZ306211A (en) * | 1995-04-07 | 1998-08-26 | Abbott Lab | Calcium supplements, in particular beverage concentrates, with vitamin d and a calcium source |
US5609897A (en) * | 1995-04-07 | 1997-03-11 | Abbott Laboratories | Powdered beverage concentrate or additive fortified with calcium and vitamin D |
JP4493736B2 (ja) | 1995-09-01 | 2010-06-30 | 日本水産株式会社 | キチンを含有するミネラル吸収促進性組成物およびミネラル吸収促進用添加剤 |
US5855936A (en) * | 1997-03-21 | 1999-01-05 | Nestec S.A. | Food fortification |
CN1090006C (zh) * | 1997-03-24 | 2002-09-04 | 丸尾钙株式会社 | 食品添加剂料浆组合物和粉末组合物以及含该添加剂的食品组合物 |
JPH11313634A (ja) * | 1998-03-12 | 1999-11-16 | Internatl Flavors & Fragrances Inc <Iff> | 呈味剤とその製造方法 |
EP0960572A1 (en) * | 1998-05-12 | 1999-12-01 | N.V. Nutricia | Nutritional composition for the treatment of pressure ulcers |
JP2000026283A (ja) * | 1998-07-10 | 2000-01-25 | Nisshin Oil Mills Ltd:The | 油性組成物を含有した粉末組成物 |
US6455082B1 (en) * | 1999-04-26 | 2002-09-24 | Nestec S.A. | Shelf-stable calcium fortified milk and dairy products |
JP2001186863A (ja) * | 2000-01-05 | 2001-07-10 | Maruo Calcium Co Ltd | 食品添加剤スラリー組成物及びパウダー組成物、及びこれを含有する食品組成物 |
JP3563343B2 (ja) | 2000-11-10 | 2004-09-08 | 株式会社東洋新薬 | カルシウム利用効率が向上した食物繊維含有食品 |
JP2002223737A (ja) * | 2001-02-02 | 2002-08-13 | Dai Ichi Kogyo Seiyaku Co Ltd | カルシウム強化飲料用分散剤、及びカルシウム含有粉末 |
JP4390428B2 (ja) * | 2001-05-01 | 2009-12-24 | 株式会社林原生物化学研究所 | 含カルシウム組織強化剤 |
DE10127897B4 (de) * | 2001-06-08 | 2006-04-20 | Bionorica Ag | Manteltablette mit Pflanzentrockenextrakten |
US20030203097A1 (en) * | 2002-04-24 | 2003-10-30 | The Procter & Gamble Company | Acidic compositions comprising protein and fiber and processes of their preparation |
US7138151B2 (en) * | 2002-11-22 | 2006-11-21 | Unilab Pharmatech, Ltd. | Calcium-fortified acidic beverages |
JP2004292382A (ja) * | 2003-03-27 | 2004-10-21 | Kirin Brewery Co Ltd | ミネラル吸収促進剤及び骨粗鬆症用予防及び/又は改善剤 |
JP2005047820A (ja) * | 2003-07-29 | 2005-02-24 | Taiyo Kagaku Co Ltd | 整腸用組成物 |
KR20030078050A (ko) * | 2003-09-01 | 2003-10-04 | 주식회사 엠에스씨 | 고분산성 유청칼슘 조성물 및 그 제조방법 |
CN1833727B (zh) * | 2005-03-18 | 2010-07-28 | 潘思源 | 阿拉伯树胶在建立动物模型和降低血胆固醇中的用途 |
US20070003671A1 (en) * | 2005-07-01 | 2007-01-04 | Anglea Timothy A | Two-part calcium fortified compositions and methods of making the same |
CN101484146A (zh) * | 2006-05-23 | 2009-07-15 | 奥拉黑尔斯公司 | 木糖醇锭剂及其用法 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107929313A (zh) * | 2017-11-21 | 2018-04-20 | 上海金城药业有限公司 | 用于预防和治疗钙缺乏症的天然型牡蛎碳酸钙制剂及其制备方法 |
CN107929313B (zh) * | 2017-11-21 | 2021-02-19 | 上海金城素智药业有限公司 | 用于预防和治疗钙缺乏症的天然型牡蛎碳酸钙制剂及其制备方法 |
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EP2298276B1 (en) | 2020-01-15 |
BRPI0708061A2 (pt) | 2011-05-17 |
AR059577A1 (es) | 2008-04-16 |
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SG169979A1 (en) | 2011-04-29 |
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US20090098222A1 (en) | 2009-04-16 |
AU2007215753B2 (en) | 2013-04-18 |
CA2642248A1 (en) | 2007-08-23 |
KR20080103528A (ko) | 2008-11-27 |
CN102755374A (zh) | 2012-10-31 |
RU2008137129A (ru) | 2010-03-27 |
AU2007215753A1 (en) | 2007-08-23 |
RU2428193C2 (ru) | 2011-09-10 |
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