CN101360499B - 吡唑并[1,5-a]嘧啶衍生物在制备抑制蛋白激酶的药物中的用途 - Google Patents

吡唑并[1,5-a]嘧啶衍生物在制备抑制蛋白激酶的药物中的用途 Download PDF

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CN101360499B
CN101360499B CN200680045935.5A CN200680045935A CN101360499B CN 101360499 B CN101360499 B CN 101360499B CN 200680045935 A CN200680045935 A CN 200680045935A CN 101360499 B CN101360499 B CN 101360499B
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compound
aryl
heteroaryl
formula
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CN101360499A (zh
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T·J·古兹
K·帕契
M·P·德耶
D·A·帕瑞
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Merck Sharp and Dohme BV
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Schering Corp
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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  • Heart & Thoracic Surgery (AREA)
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  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200680045935.5A 2005-10-06 2006-10-04 吡唑并[1,5-a]嘧啶衍生物在制备抑制蛋白激酶的药物中的用途 Active CN101360499B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72415805P 2005-10-06 2005-10-06
US60/724,158 2005-10-06
PCT/US2006/038917 WO2007044441A2 (en) 2005-10-06 2006-10-04 Use of pyrazolo [1 , 5 -a] pyrimidine derivatives for inhibiting protein kinases methods for inhibiting protein kinases

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CN101360499A CN101360499A (zh) 2009-02-04
CN101360499B true CN101360499B (zh) 2015-10-07

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US (2) US20070082900A1 (enExample)
EP (1) EP1942900B1 (enExample)
JP (3) JP5152922B2 (enExample)
CN (1) CN101360499B (enExample)
BR (1) BRPI0616985B1 (enExample)
CA (1) CA2627623C (enExample)
NO (1) NO20082093L (enExample)
NZ (1) NZ567151A (enExample)
TW (1) TWI421078B (enExample)
WO (1) WO2007044441A2 (enExample)
ZA (1) ZA200802998B (enExample)

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JP2012082234A (ja) 2012-04-26
WO2007044441A3 (en) 2007-07-26
US8211854B2 (en) 2012-07-03
ZA200802998B (en) 2009-10-28
NO20082093L (no) 2008-07-03
WO2007044441A2 (en) 2007-04-19
AU2006302435A1 (en) 2007-04-19
JP5152922B2 (ja) 2013-02-27
JP2009511486A (ja) 2009-03-19
US20100125068A1 (en) 2010-05-20
US20070082900A1 (en) 2007-04-12
JP5520325B2 (ja) 2014-06-11
BRPI0616985B1 (pt) 2021-10-26
CN101360499A (zh) 2009-02-04
JP2014062129A (ja) 2014-04-10
BRPI0616985A2 (pt) 2009-08-04
TWI421078B (zh) 2014-01-01
CA2627623A1 (en) 2007-04-19
CA2627623C (en) 2014-04-22
TW200800218A (en) 2008-01-01
NZ567151A (en) 2012-03-30
EP1942900A2 (en) 2008-07-16

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