CN101360485B - 作为胶囊填充物的基于亲水性载体的双重控释基质系统 - Google Patents

作为胶囊填充物的基于亲水性载体的双重控释基质系统 Download PDF

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Publication number
CN101360485B
CN101360485B CN2006800457275A CN200680045727A CN101360485B CN 101360485 B CN101360485 B CN 101360485B CN 2006800457275 A CN2006800457275 A CN 2006800457275A CN 200680045727 A CN200680045727 A CN 200680045727A CN 101360485 B CN101360485 B CN 101360485B
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capsule
matrix
hydrogel
agents
hydrophilic carrier
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Expired - Fee Related
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CN2006800457275A
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Chinese (zh)
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CN101360485A (zh
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卡鲁纳卡尔·苏库鲁
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Pasin Rubber Co
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Banner Pharmacaps Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2006800457275A 2005-10-26 2006-10-26 作为胶囊填充物的基于亲水性载体的双重控释基质系统 Expired - Fee Related CN101360485B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73040605P 2005-10-26 2005-10-26
US60/730,406 2005-10-26
PCT/US2006/042177 WO2007050975A2 (en) 2005-10-26 2006-10-26 Hydrophilic vehicle-based dual controlled release matrix system as capsule fill

Publications (2)

Publication Number Publication Date
CN101360485A CN101360485A (zh) 2009-02-04
CN101360485B true CN101360485B (zh) 2013-04-17

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CN2006800457275A Expired - Fee Related CN101360485B (zh) 2005-10-26 2006-10-26 作为胶囊填充物的基于亲水性载体的双重控释基质系统

Country Status (6)

Country Link
US (1) US8333989B2 (https=)
EP (1) EP1959935A2 (https=)
JP (2) JP5406530B2 (https=)
CN (1) CN101360485B (https=)
CA (1) CA2627292C (https=)
WO (1) WO2007050975A2 (https=)

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CN101491549B (zh) * 2009-02-23 2011-08-03 四川珍珠制药有限公司 一种中药软胶囊及其制备方法
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WO2014060857A1 (en) * 2012-10-19 2014-04-24 Wockhardt Limited Pharmaceutical compositions of diclofenac or salts thereof
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CA2906633C (en) * 2013-03-15 2021-11-30 Warner Chilcott Company, Llc Pharmaceutical soft gelatin capsule dosage form with modified guar gum
CA2906619C (en) * 2013-03-15 2021-11-16 Warner Chilcott Company, Llc Pharmaceutical soft gelatin capsule dosage form
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CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
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AU2015222880B2 (en) 2014-02-28 2016-11-24 Banner Life Sciences Llc Controlled release enteric soft capsules of fumarate esters
US10098863B2 (en) 2014-02-28 2018-10-16 Banner Life Sciences Llc Fumarate esters
US9326947B1 (en) 2014-02-28 2016-05-03 Banner Life Sciences Llc Controlled release fumarate esters
US9636318B2 (en) 2015-08-31 2017-05-02 Banner Life Sciences Llc Fumarate ester dosage forms
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
US10772841B2 (en) 2014-04-07 2020-09-15 Patheon Softgels Inc. Opioid abuse-deterrent controlled release formulations
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Also Published As

Publication number Publication date
WO2007050975A3 (en) 2007-09-20
US8333989B2 (en) 2012-12-18
JP2013216680A (ja) 2013-10-24
JP5406530B2 (ja) 2014-02-05
US20070098783A1 (en) 2007-05-03
CN101360485A (zh) 2009-02-04
EP1959935A2 (en) 2008-08-27
JP2009513669A (ja) 2009-04-02
WO2007050975A2 (en) 2007-05-03
CA2627292C (en) 2012-04-17
CA2627292A1 (en) 2007-05-03

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Owner name: BANNER LIFE SCIENCES INC.

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