CA2627292C - Hydrophilic vehicle-based dual controlled release matrix system - Google Patents

Hydrophilic vehicle-based dual controlled release matrix system Download PDF

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Publication number
CA2627292C
CA2627292C CA2627292A CA2627292A CA2627292C CA 2627292 C CA2627292 C CA 2627292C CA 2627292 A CA2627292 A CA 2627292A CA 2627292 A CA2627292 A CA 2627292A CA 2627292 C CA2627292 C CA 2627292C
Authority
CA
Canada
Prior art keywords
agents
capsule
matrix
hydrogel
hydrophilic vehicle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2627292A
Other languages
English (en)
French (fr)
Other versions
CA2627292A1 (en
Inventor
Karunakar Sukuru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Softgels Inc
Original Assignee
Banner Pharmacaps Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banner Pharmacaps Inc filed Critical Banner Pharmacaps Inc
Publication of CA2627292A1 publication Critical patent/CA2627292A1/en
Application granted granted Critical
Publication of CA2627292C publication Critical patent/CA2627292C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2627292A 2005-10-26 2006-10-26 Hydrophilic vehicle-based dual controlled release matrix system Expired - Fee Related CA2627292C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73040605P 2005-10-26 2005-10-26
US60/730,406 2005-10-26
PCT/US2006/042177 WO2007050975A2 (en) 2005-10-26 2006-10-26 Hydrophilic vehicle-based dual controlled release matrix system as capsule fill

Publications (2)

Publication Number Publication Date
CA2627292A1 CA2627292A1 (en) 2007-05-03
CA2627292C true CA2627292C (en) 2012-04-17

Family

ID=37801480

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2627292A Expired - Fee Related CA2627292C (en) 2005-10-26 2006-10-26 Hydrophilic vehicle-based dual controlled release matrix system

Country Status (6)

Country Link
US (1) US8333989B2 (https=)
EP (1) EP1959935A2 (https=)
JP (2) JP5406530B2 (https=)
CN (1) CN101360485B (https=)
CA (1) CA2627292C (https=)
WO (1) WO2007050975A2 (https=)

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WO2014060857A1 (en) * 2012-10-19 2014-04-24 Wockhardt Limited Pharmaceutical compositions of diclofenac or salts thereof
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CA2906633C (en) * 2013-03-15 2021-11-30 Warner Chilcott Company, Llc Pharmaceutical soft gelatin capsule dosage form with modified guar gum
CA2906619C (en) * 2013-03-15 2021-11-16 Warner Chilcott Company, Llc Pharmaceutical soft gelatin capsule dosage form
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US10098863B2 (en) 2014-02-28 2018-10-16 Banner Life Sciences Llc Fumarate esters
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GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
US10772841B2 (en) 2014-04-07 2020-09-15 Patheon Softgels Inc. Opioid abuse-deterrent controlled release formulations
US10772842B2 (en) 2015-01-09 2020-09-15 Patheon Softgels Inc. Abuse-deterrent opioids
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US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
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Also Published As

Publication number Publication date
WO2007050975A3 (en) 2007-09-20
US8333989B2 (en) 2012-12-18
JP2013216680A (ja) 2013-10-24
CN101360485B (zh) 2013-04-17
JP5406530B2 (ja) 2014-02-05
US20070098783A1 (en) 2007-05-03
CN101360485A (zh) 2009-02-04
EP1959935A2 (en) 2008-08-27
JP2009513669A (ja) 2009-04-02
WO2007050975A2 (en) 2007-05-03
CA2627292A1 (en) 2007-05-03

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Effective date: 20201026