CN101340923B - 用乙醇沉淀的菜豆提取物,其应用及制剂 - Google Patents
用乙醇沉淀的菜豆提取物,其应用及制剂 Download PDFInfo
- Publication number
- CN101340923B CN101340923B CN2006800480680A CN200680048068A CN101340923B CN 101340923 B CN101340923 B CN 101340923B CN 2006800480680 A CN2006800480680 A CN 2006800480680A CN 200680048068 A CN200680048068 A CN 200680048068A CN 101340923 B CN101340923 B CN 101340923B
- Authority
- CN
- China
- Prior art keywords
- extract
- alpha
- ethanol
- phytohaemagglutinin
- amylase inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Extraction Or Liquid Replacement (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
Claims (5)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2005A002450 | 2005-12-22 | ||
IT002450A ITMI20052450A1 (it) | 2005-12-22 | 2005-12-22 | Estratti di phaseolus vulgaris loro uso e formulazioni che li contengono |
PCT/EP2006/012012 WO2007071334A2 (en) | 2005-12-22 | 2006-12-13 | Ethanol-precipitated phaseolus vulgaris extracts, their use and formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101340923A CN101340923A (zh) | 2009-01-07 |
CN101340923B true CN101340923B (zh) | 2013-11-06 |
Family
ID=37888415
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2006800480680A Active CN101340923B (zh) | 2005-12-22 | 2006-12-13 | 用乙醇沉淀的菜豆提取物,其应用及制剂 |
Country Status (18)
Country | Link |
---|---|
US (2) | US20090169657A1 (zh) |
EP (1) | EP1962877B1 (zh) |
JP (1) | JP5452931B2 (zh) |
KR (1) | KR101449763B1 (zh) |
CN (1) | CN101340923B (zh) |
AU (1) | AU2006328983B2 (zh) |
BR (1) | BRPI0620054A8 (zh) |
CA (1) | CA2634345C (zh) |
DK (1) | DK1962877T3 (zh) |
ES (1) | ES2813929T3 (zh) |
HK (1) | HK1127995A1 (zh) |
IL (1) | IL192292A (zh) |
IT (1) | ITMI20052450A1 (zh) |
NO (1) | NO346419B1 (zh) |
PT (1) | PT1962877T (zh) |
RU (1) | RU2426552C2 (zh) |
SI (1) | SI1962877T1 (zh) |
WO (1) | WO2007071334A2 (zh) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1967198E (pt) | 2007-03-07 | 2009-06-15 | Indena Spa | Formulações contendo extractos de cynara scolymus e phaseolus vulgaris úteis no tratamento da obesidade |
CN101555275B (zh) * | 2009-05-08 | 2011-09-28 | 广东省食品工业研究所 | 一种利用生物酶法制备α-淀粉酶抑制剂的方法 |
KR20110138001A (ko) * | 2010-06-18 | 2011-12-26 | (주)아모레퍼시픽 | 유색콩 추출물을 함유하는 조성물 |
ITMI20121727A1 (it) * | 2012-10-12 | 2014-04-13 | Indena Spa | Formulazioni per il trattamento e la prevenzione dell'obesita' |
TW201427674A (zh) * | 2013-01-15 | 2014-07-16 | ji-min Song | 花豆種子萃取物及其製備方法與用途 |
US9290752B2 (en) | 2013-03-13 | 2016-03-22 | Sunny Delight Beverages Co. | Process for enhancing the amylase inhibitory efficacy from phaseolus vulgaris extracts |
WO2016114740A1 (en) * | 2015-01-14 | 2016-07-21 | Kutsanyan Akop Surikovych | Method for producing a complex of biologically active substances exhibiting hypoglycemic activity |
CN116270793A (zh) * | 2023-02-07 | 2023-06-23 | 湖南朗林生物资源股份有限公司 | 一种白芸豆提取物的制备方法及其应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2628757A1 (de) * | 1976-06-26 | 1977-12-29 | Guenter Dr Woeber | Amylase inhibitor |
EP1295535A2 (en) * | 2001-09-25 | 2003-03-26 | Pharmachem Laboratories, Inc. | Phaseolamin compositions and methods for using the same |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06116197A (ja) | 1992-09-07 | 1994-04-26 | Max Fuakutaa Kk | 新規ラジカルスカベンジャー |
MXPA05000092A (es) * | 2002-06-28 | 2005-09-30 | Pharmachem Lab Inc | Inhibidores de amilasa purificado y proceso novedoso para obtener el mismo. |
US20040131749A1 (en) * | 2002-08-29 | 2004-07-08 | Archer-Daniels-Midland Company | Phytochemicals from edible bean process streams |
ITMI20040619A1 (it) * | 2004-03-30 | 2004-06-30 | Consiglio Nazionale Ricerche | Estratto purificato di inibitore dell'alfa-amilasi da fagioli essenzialmente privi di fitoemoagglutinina procedimento di estrazione e composizioni che lo contengono |
US7553502B2 (en) * | 2007-03-07 | 2009-06-30 | Indena S.P.A. | Formulations of alpha-amylase inhibitors with alpha-glucosidase inhibitors useful in the treatment of diabetes and obesity |
PT1967198E (pt) * | 2007-03-07 | 2009-06-15 | Indena Spa | Formulações contendo extractos de cynara scolymus e phaseolus vulgaris úteis no tratamento da obesidade |
-
2005
- 2005-12-22 IT IT002450A patent/ITMI20052450A1/it unknown
-
2006
- 2006-12-13 US US12/158,063 patent/US20090169657A1/en not_active Abandoned
- 2006-12-13 DK DK06829580.7T patent/DK1962877T3/da active
- 2006-12-13 BR BRPI0620054A patent/BRPI0620054A8/pt not_active Application Discontinuation
- 2006-12-13 SI SI200632384T patent/SI1962877T1/sl unknown
- 2006-12-13 JP JP2008546204A patent/JP5452931B2/ja active Active
- 2006-12-13 EP EP06829580.7A patent/EP1962877B1/en active Active
- 2006-12-13 PT PT68295807T patent/PT1962877T/pt unknown
- 2006-12-13 CN CN2006800480680A patent/CN101340923B/zh active Active
- 2006-12-13 KR KR1020087014705A patent/KR101449763B1/ko active IP Right Grant
- 2006-12-13 WO PCT/EP2006/012012 patent/WO2007071334A2/en active Application Filing
- 2006-12-13 AU AU2006328983A patent/AU2006328983B2/en active Active
- 2006-12-13 CA CA2634345A patent/CA2634345C/en active Active
- 2006-12-13 ES ES06829580T patent/ES2813929T3/es active Active
- 2006-12-13 RU RU2008124974/15A patent/RU2426552C2/ru active
-
2008
- 2008-06-19 IL IL192292A patent/IL192292A/en active IP Right Grant
- 2008-06-19 NO NO20082729A patent/NO346419B1/no unknown
-
2009
- 2009-06-19 HK HK09105551.1A patent/HK1127995A1/xx unknown
-
2017
- 2017-07-07 US US15/643,900 patent/US11241470B2/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2628757A1 (de) * | 1976-06-26 | 1977-12-29 | Guenter Dr Woeber | Amylase inhibitor |
EP1295535A2 (en) * | 2001-09-25 | 2003-03-26 | Pharmachem Laboratories, Inc. | Phaseolamin compositions and methods for using the same |
Non-Patent Citations (16)
Title |
---|
acute * |
Antonia M. Iguti, et al..Occurrence and purification of α-amylase isoinhibitors in bean (Phaseolus vulgaris L.) varieties.《J. Agric. Food Chem.》.1991,第39卷(第12期),2131-2136. |
Blocking carbohydrate absorption and weight loss: a clinical trial using phase 2 brand proprietary fractionated white bean extract;Udani J., et al.;《Altern. Med. Rev.》;20040331;第9卷(第1期);63-69 * |
Bo-Linn G. W., et al..Starch blockers--their effect on calorie absorption from a high-starch meal.《New England Journal of Medicine》.1982,第307卷(第23期),1413-1416. |
Hypoglycaemic and anorexigenic activities of an α-amylase inhibitor from white kidney beans (Phaseolus vulgaris) in Wistar rats;Tormo M. A., et al.;《British Journal of Nutrition》;20041231;第92卷;785-790 * |
Joseph R. Powers, et al..Purification and some physical and chemical properties of red kidney bean (Phaseolus vulgaris) α-amylase inhibitor.《Journal of Food Biochemistry》.1977,第1卷217-238. |
Lajolo F. M., et al..Purification of Alpha Amylase Inhibitor of Black Bean Phaseolus-vulgaris Cultivar RICO-23.《Ciencia E Tecnologia de Alimentos》.1984,第4卷(第1期),1-11. |
Occurrence and purification of α-amylase isoinhibitors in bean (Phaseolus vulgaris L.) varieties;Antonia M. Iguti, et al.;《J. Agric. Food Chem.》;19911231;第39卷(第12期);2131-2136 * |
Purification and some physical and chemical properties of red kidney bean (Phaseolus vulgaris) α-amylase inhibitor;Joseph R. Powers, et al.;《Journal of Food Biochemistry》;19771231;第1卷;217-238 * |
Purification of Alpha Amylase Inhibitor of Black Bean Phaseolus-vulgaris Cultivar RICO-23;Lajolo F. M., et al.;《Ciencia E Tecnologia de Alimentos》;19841231;第4卷(第1期);1-11 * |
ronique Le Berre-Anton, et al..Characterization and functional properties of the α-amylase inhibitor (α-AI) from kidney bean (Phaseolus vulgaris) seeds.《Biochimica et Biophysica Acta》.1997,第1343卷31-40. * |
Starch blockers--their effect on calorie absorption from a high-starch meal;Bo-Linn G. W., et al.;《New England Journal of Medicine》;19821202;第307卷(第23期);1413-1416 * |
Tormo M. A., et al..Hypoglycaemic and anorexigenic activities of an α-amylase inhibitor from white kidney beans (Phaseolus vulgaris) in Wistar rats.《British Journal of Nutrition》.2004,第92卷785-790. |
Udani J., et al..Blocking carbohydrate absorption and weight loss: a clinical trial using phase 2 brand proprietary fractionated white bean extract.《Altern. Med. Rev.》.2004,第9卷(第1期),63-69. |
Ve´ |
Ve& * |
Also Published As
Publication number | Publication date |
---|---|
US11241470B2 (en) | 2022-02-08 |
NO346419B1 (no) | 2022-07-18 |
HK1127995A1 (en) | 2009-10-16 |
RU2426552C2 (ru) | 2011-08-20 |
CA2634345C (en) | 2016-09-27 |
BRPI0620054A2 (pt) | 2011-11-01 |
DK1962877T3 (da) | 2020-08-31 |
PT1962877T (pt) | 2020-09-04 |
CA2634345A1 (en) | 2007-06-28 |
US20090169657A1 (en) | 2009-07-02 |
JP5452931B2 (ja) | 2014-03-26 |
ES2813929T3 (es) | 2021-03-25 |
CN101340923A (zh) | 2009-01-07 |
WO2007071334A2 (en) | 2007-06-28 |
AU2006328983A1 (en) | 2007-06-28 |
RU2008124974A (ru) | 2009-12-27 |
ITMI20052450A1 (it) | 2007-06-23 |
KR20080080127A (ko) | 2008-09-02 |
EP1962877A2 (en) | 2008-09-03 |
KR101449763B1 (ko) | 2014-10-13 |
AU2006328983B2 (en) | 2012-06-28 |
US20170333508A1 (en) | 2017-11-23 |
EP1962877B1 (en) | 2020-07-22 |
IL192292A (en) | 2013-05-30 |
NO20082729L (no) | 2008-07-08 |
IL192292A0 (en) | 2008-12-29 |
SI1962877T1 (sl) | 2020-09-30 |
JP2009520716A (ja) | 2009-05-28 |
WO2007071334A3 (en) | 2007-09-13 |
BRPI0620054A8 (pt) | 2018-12-26 |
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