CN101253173A - 羟基取代的1h-咪唑并吡啶和方法 - Google Patents

羟基取代的1h-咪唑并吡啶和方法 Download PDF

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Publication number
CN101253173A
CN101253173A CNA2006800319190A CN200680031919A CN101253173A CN 101253173 A CN101253173 A CN 101253173A CN A2006800319190 A CNA2006800319190 A CN A2006800319190A CN 200680031919 A CN200680031919 A CN 200680031919A CN 101253173 A CN101253173 A CN 101253173A
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China
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group
alkyl
heteroaryl
alkylidene group
aryl
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CNA2006800319190A
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English (en)
Chinese (zh)
Inventor
J·F·小德拉里亚
W·H·莫泽
M·R·拉德默
G·W·格里斯格里贝尔
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Pfizer Inc
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Pfizer Inc
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Publication of CN101253173A publication Critical patent/CN101253173A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNA2006800319190A 2005-09-02 2006-09-01 羟基取代的1h-咪唑并吡啶和方法 Pending CN101253173A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71370405P 2005-09-02 2005-09-02
US60/713,704 2005-09-02

Publications (1)

Publication Number Publication Date
CN101253173A true CN101253173A (zh) 2008-08-27

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Country Status (20)

Country Link
US (2) US20100152230A1 (https=)
EP (1) EP1924581A1 (https=)
JP (1) JP4584335B2 (https=)
KR (1) KR20080031496A (https=)
CN (1) CN101253173A (https=)
AU (1) AU2006287157A1 (https=)
BR (1) BRPI0615250A2 (https=)
CA (1) CA2620933A1 (https=)
CR (1) CR9781A (https=)
EA (1) EA200800396A1 (https=)
EC (1) ECSP088225A (https=)
IL (1) IL189262A0 (https=)
MA (1) MA29759B1 (https=)
MX (1) MX2008002414A (https=)
NO (1) NO20081393L (https=)
RS (1) RS20080128A (https=)
SV (1) SV2009002832A (https=)
TN (1) TNSN08099A1 (https=)
WO (1) WO2007028129A1 (https=)
ZA (1) ZA200801645B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103450198A (zh) * 2012-05-29 2013-12-18 首都医科大学 咪唑并吡啶并咪唑-3-取代乙酸苄酯、其合成、抗肿瘤活性及应用
CN117466808A (zh) * 2023-12-27 2024-01-30 烟台新药创制山东省实验室 一种6-烷基-2,4-二羟基吡啶类衍生物的制备方法

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103450198A (zh) * 2012-05-29 2013-12-18 首都医科大学 咪唑并吡啶并咪唑-3-取代乙酸苄酯、其合成、抗肿瘤活性及应用
CN103450198B (zh) * 2012-05-29 2015-07-08 首都医科大学 咪唑并吡啶并咪唑-3-取代乙酸苄酯、其合成、抗肿瘤活性及应用
CN117466808A (zh) * 2023-12-27 2024-01-30 烟台新药创制山东省实验室 一种6-烷基-2,4-二羟基吡啶类衍生物的制备方法
CN117466808B (zh) * 2023-12-27 2024-03-12 烟台新药创制山东省实验室 一种6-烷基-2,4-二羟基吡啶类衍生物的制备方法

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Publication number Publication date
KR20080031496A (ko) 2008-04-08
RS20080128A (sr) 2009-05-06
EP1924581A1 (en) 2008-05-28
ECSP088225A (es) 2008-03-26
JP2009507036A (ja) 2009-02-19
MX2008002414A (es) 2008-03-27
SV2009002832A (es) 2009-02-19
BRPI0615250A2 (pt) 2011-05-10
TNSN08099A1 (fr) 2009-07-14
MA29759B1 (fr) 2008-09-01
ZA200801645B (en) 2010-08-25
CA2620933A1 (en) 2007-03-08
EA200800396A1 (ru) 2008-08-29
JP4584335B2 (ja) 2010-11-17
WO2007028129A1 (en) 2007-03-08
US20100152230A1 (en) 2010-06-17
US20120035209A1 (en) 2012-02-09
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CR9781A (es) 2008-03-26
IL189262A0 (en) 2008-06-05

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