EA200800396A1 - Гидроксизамещенные 1н-имидазопиридины и способы - Google Patents

Гидроксизамещенные 1н-имидазопиридины и способы

Info

Publication number
EA200800396A1
EA200800396A1 EA200800396A EA200800396A EA200800396A1 EA 200800396 A1 EA200800396 A1 EA 200800396A1 EA 200800396 A EA200800396 A EA 200800396A EA 200800396 A EA200800396 A EA 200800396A EA 200800396 A1 EA200800396 A1 EA 200800396A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
compounds
imidazopiridines
hydroxymediated
hydroxy
Prior art date
Application number
EA200800396A
Other languages
English (en)
Inventor
Джозеф Ф. мл. Деллария
Уильям Г. Моузер
Мэттью Р. Радмер
Джордж У. Гризгрейбер
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA200800396A1 publication Critical patent/EA200800396A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Раскрыты гидроксизамещенные 1H-имидазо[4,5-с]пиридин-4-амины с заместителем гидрокси в положении 2, фармацевтические композиции, содержащие эти соединения, способы получения этих соединений, промежуточные соединения и способы применения этих соединений в качестве иммуномодуляторов для индуцирования биосинтеза цитокинов у животных и для лечения заболеваний, в том числе вирусных и неопластических заболеваний.
EA200800396A 2005-09-02 2006-09-01 Гидроксизамещенные 1н-имидазопиридины и способы EA200800396A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71370405P 2005-09-02 2005-09-02
PCT/US2006/034427 WO2007028129A1 (en) 2005-09-02 2006-09-01 Hydroxy substituted 1h-imidazopyridines and methods

Publications (1)

Publication Number Publication Date
EA200800396A1 true EA200800396A1 (ru) 2008-08-29

Family

ID=37561219

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200800396A EA200800396A1 (ru) 2005-09-02 2006-09-01 Гидроксизамещенные 1н-имидазопиридины и способы

Country Status (20)

Country Link
US (2) US20100152230A1 (ru)
EP (1) EP1924581A1 (ru)
JP (1) JP4584335B2 (ru)
KR (1) KR20080031496A (ru)
CN (1) CN101253173A (ru)
AU (1) AU2006287157A1 (ru)
BR (1) BRPI0615250A2 (ru)
CA (1) CA2620933A1 (ru)
CR (1) CR9781A (ru)
EA (1) EA200800396A1 (ru)
EC (1) ECSP088225A (ru)
IL (1) IL189262A0 (ru)
MA (1) MA29759B1 (ru)
MX (1) MX2008002414A (ru)
NO (1) NO20081393L (ru)
RS (1) RS20080128A (ru)
SV (1) SV2009002832A (ru)
TN (1) TNSN08099A1 (ru)
WO (1) WO2007028129A1 (ru)
ZA (1) ZA200801645B (ru)

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Also Published As

Publication number Publication date
AU2006287157A1 (en) 2007-03-08
MA29759B1 (fr) 2008-09-01
KR20080031496A (ko) 2008-04-08
NO20081393L (no) 2008-05-28
RS20080128A (en) 2009-05-06
CR9781A (es) 2008-03-26
CN101253173A (zh) 2008-08-27
ZA200801645B (en) 2010-08-25
MX2008002414A (es) 2008-03-27
BRPI0615250A2 (pt) 2011-05-10
IL189262A0 (en) 2008-06-05
US20120035209A1 (en) 2012-02-09
JP4584335B2 (ja) 2010-11-17
SV2009002832A (es) 2009-02-19
ECSP088225A (es) 2008-03-26
US20100152230A1 (en) 2010-06-17
TNSN08099A1 (fr) 2009-07-14
JP2009507036A (ja) 2009-02-19
CA2620933A1 (en) 2007-03-08
EP1924581A1 (en) 2008-05-28
WO2007028129A1 (en) 2007-03-08

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