WO2007143526A3 - Substituted tetrahydroimidazonaphthyridines and methods - Google Patents

Substituted tetrahydroimidazonaphthyridines and methods Download PDF

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Publication number
WO2007143526A3
WO2007143526A3 PCT/US2007/070181 US2007070181W WO2007143526A3 WO 2007143526 A3 WO2007143526 A3 WO 2007143526A3 US 2007070181 W US2007070181 W US 2007070181W WO 2007143526 A3 WO2007143526 A3 WO 2007143526A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
compounds
tetrahydroimidazonaphthyridines
substituted
naphthyridines
Prior art date
Application number
PCT/US2007/070181
Other languages
French (fr)
Other versions
WO2007143526A2 (en
Inventor
Joseph F Dellaria Jr
William H Moser
Matthew R Radmer
Tushar A Kshirsagar
Philip D Heppner
Original Assignee
Coley Pharm Group Inc
Joseph F Dellaria Jr
William H Moser
Matthew R Radmer
Tushar A Kshirsagar
Philip D Heppner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coley Pharm Group Inc, Joseph F Dellaria Jr, William H Moser, Matthew R Radmer, Tushar A Kshirsagar, Philip D Heppner filed Critical Coley Pharm Group Inc
Publication of WO2007143526A2 publication Critical patent/WO2007143526A2/en
Publication of WO2007143526A3 publication Critical patent/WO2007143526A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

6,7,8,9-Tetrahydro-1H-imidazo[4,5-c]naphthyridines with a substituent at the 6-, 7-, 8-, or 9-position nitrogen atom, pharmaceutical compositions containing these compounds, methods of making the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.
PCT/US2007/070181 2006-06-05 2007-06-01 Substituted tetrahydroimidazonaphthyridines and methods WO2007143526A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80392706P 2006-06-05 2006-06-05
US60/803,927 2006-06-05

Publications (2)

Publication Number Publication Date
WO2007143526A2 WO2007143526A2 (en) 2007-12-13
WO2007143526A3 true WO2007143526A3 (en) 2008-02-07

Family

ID=38802237

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/070181 WO2007143526A2 (en) 2006-06-05 2007-06-01 Substituted tetrahydroimidazonaphthyridines and methods

Country Status (1)

Country Link
WO (1) WO2007143526A2 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007502293A (en) 2003-08-12 2007-02-08 スリーエム イノベイティブ プロパティズ カンパニー Hydroxylamine-substituted imidazo-containing compounds
EP1658076B1 (en) 2003-08-27 2013-03-06 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted imidazoquinolines
CA2537763A1 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for cd5+ b cell lymphoma
AR046046A1 (en) 2003-10-03 2005-11-23 3M Innovative Properties Co IMIDAZOQUINOLINAS ALCOXI SUBSTITUTED. PHARMACEUTICAL COMPOSITIONS.
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
CA2545774A1 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Oxime substituted imidazo ring compounds
CA2545825A1 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Hydroxylamine substituted imidazo ring compounds
BRPI0416936A (en) 2003-11-25 2007-01-16 3M Innovative Properties Co substituted imidazo ring systems and methods
EP1701955A1 (en) 2003-12-29 2006-09-20 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
EP1699788A2 (en) 2003-12-30 2006-09-13 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl and imidazonaphthyridinyl sulfonamides
AU2005228150A1 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
JP5543068B2 (en) 2004-12-30 2014-07-09 スリーエム イノベイティブ プロパティズ カンパニー Chiral fused [1,2] imidazo [4,5-c] cyclic compound
US8034938B2 (en) 2004-12-30 2011-10-11 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
US9248127B2 (en) 2005-02-04 2016-02-02 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
EP1846405A2 (en) 2005-02-11 2007-10-24 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo 4,5-c ring compounds and methods
US7943610B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company Pyrazolopyridine-1,4-diamines and analogs thereof
CA2602590A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
JP6873980B2 (en) * 2015-09-14 2021-05-19 ファイザー・インク Novel imidazole [4,5-c] quinoline and imidazole [4,5-c] [1,5] naphthylidine derivatives as LRRK2 inhibitors
US20220306633A1 (en) * 2021-03-22 2022-09-29 Incyte Corporation Imidazole and triazole kras inhibitors

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194425B1 (en) * 1997-12-11 2001-02-27 3M Innovative Properties Company Imidazonaphthyridines
US6518280B2 (en) * 1998-12-11 2003-02-11 3M Innovative Properties Company Imidazonaphthyridines
US20040147543A1 (en) * 2002-12-20 2004-07-29 3M Innovative Properties Company Aryl substituted imidazoquinolines

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194425B1 (en) * 1997-12-11 2001-02-27 3M Innovative Properties Company Imidazonaphthyridines
US6518280B2 (en) * 1998-12-11 2003-02-11 3M Innovative Properties Company Imidazonaphthyridines
US20040147543A1 (en) * 2002-12-20 2004-07-29 3M Innovative Properties Company Aryl substituted imidazoquinolines

Also Published As

Publication number Publication date
WO2007143526A2 (en) 2007-12-13

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