CN101152185B - 杂环化合物作为scce抑制剂的用途 - Google Patents

杂环化合物作为scce抑制剂的用途 Download PDF

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Publication number
CN101152185B
CN101152185B CN2007101613027A CN200710161302A CN101152185B CN 101152185 B CN101152185 B CN 101152185B CN 2007101613027 A CN2007101613027 A CN 2007101613027A CN 200710161302 A CN200710161302 A CN 200710161302A CN 101152185 B CN101152185 B CN 101152185B
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ketone
phenyl
piperazine
benzo
azepine
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CN101152185A (zh
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M·林舍滕
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Arexis AB
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Arexis AB
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cosmetics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN2007101613027A 2003-06-06 2004-06-07 杂环化合物作为scce抑制剂的用途 Expired - Fee Related CN101152185B (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DKPA200300840 2003-06-06
DKPA200300844 2003-06-06
DKPA200300844 2003-06-06
DKPA200300842 2003-06-06
DKPA200300842 2003-06-06
DKPA200300840 2003-06-06
DKPA200300843 2003-06-06
DKPA200300843 2003-06-06

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CNB200480015752XA Division CN100518740C (zh) 2003-06-06 2004-06-07 杂环化合物作为scce抑制剂的制药用途

Publications (2)

Publication Number Publication Date
CN101152185A CN101152185A (zh) 2008-04-02
CN101152185B true CN101152185B (zh) 2010-12-08

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US (1) US7872052B2 (https=)
EP (1) EP1631295B1 (https=)
JP (1) JP5044214B2 (https=)
KR (2) KR101205257B1 (https=)
CN (1) CN101152185B (https=)
AT (1) ATE459359T1 (https=)
CA (1) CA2525383C (https=)
CY (1) CY1110084T1 (https=)
DE (1) DE602004025803D1 (https=)
DK (1) DK1631295T3 (https=)
ES (1) ES2341545T3 (https=)
NO (1) NO20060091L (https=)
NZ (1) NZ543636A (https=)
PL (1) PL1631295T3 (https=)
PT (1) PT1631295E (https=)
SI (1) SI1631295T1 (https=)
WO (1) WO2004108139A2 (https=)

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Publication number Publication date
WO2004108139A2 (en) 2004-12-16
WO2004108139A8 (en) 2005-04-28
HK1091731A1 (zh) 2007-01-26
WO2004108139A3 (en) 2005-03-10
DK1631295T3 (da) 2010-06-21
CN101152185A (zh) 2008-04-02
CY1110084T1 (el) 2015-01-14
ES2341545T3 (es) 2010-06-22
JP2006526581A (ja) 2006-11-24
AU2004244704A1 (en) 2004-12-16
CA2525383A1 (en) 2004-12-16
CA2525383C (en) 2012-03-06
KR20110120960A (ko) 2011-11-04
EP1631295B1 (en) 2010-03-03
KR101099409B1 (ko) 2011-12-27
SI1631295T1 (sl) 2010-06-30
EP1631295A2 (en) 2006-03-08
JP5044214B2 (ja) 2012-10-10
PL1631295T3 (pl) 2010-09-30
NZ543636A (en) 2009-07-31
ATE459359T1 (de) 2010-03-15
KR20060008331A (ko) 2006-01-26
US20060258651A1 (en) 2006-11-16
PT1631295E (pt) 2010-05-24
KR101205257B1 (ko) 2012-11-27
DE602004025803D1 (de) 2010-04-15
NO20060091L (no) 2006-03-06
US7872052B2 (en) 2011-01-18
HK1120209A1 (en) 2009-03-27

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