CN101098697B - 与抑制巨噬细胞游走抑制因子有关的化合物、组合物、其制备方法和使用方法 - Google Patents

与抑制巨噬细胞游走抑制因子有关的化合物、组合物、其制备方法和使用方法 Download PDF

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CN101098697B
CN101098697B CN2005800098795A CN200580009879A CN101098697B CN 101098697 B CN101098697 B CN 101098697B CN 2005800098795 A CN2005800098795 A CN 2005800098795A CN 200580009879 A CN200580009879 A CN 200580009879A CN 101098697 B CN101098697 B CN 101098697B
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alkyl
phenyl
cycloalkyl
compound
heteroaryl
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CN101098697A (zh
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T·西莱克
V·D·L·克鲁兹
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Cytokine Pharmasciences Inc
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    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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CN2005800098795A 2004-03-26 2005-03-28 与抑制巨噬细胞游走抑制因子有关的化合物、组合物、其制备方法和使用方法 Expired - Fee Related CN101098697B (zh)

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US55644004P 2004-03-26 2004-03-26
US06/556,440 2004-03-26
PCT/US2005/010444 WO2005094329A2 (en) 2004-03-26 2005-03-28 Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor

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CN101098697A CN101098697A (zh) 2008-01-02
CN101098697B true CN101098697B (zh) 2010-11-10

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US (3) US20050250826A1 (enExample)
EP (1) EP1727542A4 (enExample)
JP (1) JP2007530598A (enExample)
CN (1) CN101098697B (enExample)
AU (1) AU2005228417A1 (enExample)
BR (1) BRPI0507818A (enExample)
CA (1) CA2557166C (enExample)
MX (1) MXPA06010793A (enExample)
WO (1) WO2005094329A2 (enExample)

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EP2004192B1 (en) 2006-03-24 2014-03-12 The Feinstein Institute for Medical Research Modified macrophage migration inhibitory factor inhibitors
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SI2576523T1 (sl) 2010-05-27 2016-05-31 E.I. du Pont de Nemours and Company Chestnut Run Plaza 974 Center Road Kristalinične oblike 4-(5-(3-kloro-5-(trifluorometil)fenil)-4,5-dihidro 5-(trifluorometil)-3-izoksazolil)-N-(2-okso-2-((2,2,2-trifluoroetil) amino)etil)-1 naftalenkarboksamida
JP2014526886A (ja) 2011-07-15 2014-10-09 モルフォシス・アー・ゲー マクロファージ遊走阻止因子（ｍｉｆ）とｄ−ドーパクロームトートメラーゼ（ｄ−ｄｔ）に交差反応性がある抗体
PT2750677T (pt) 2011-08-30 2017-07-03 Chdi Foundation Inc Inibidores de quinurenina-3-monooxigenase, composições farmacêuticas e métodos de utilização dos mesmos
WO2013033068A1 (en) 2011-08-30 2013-03-07 Stephen Martin Courtney Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
WO2013161933A1 (ja) * 2012-04-26 2013-10-31 富山化学工業株式会社 重水素化含窒素複素環カルボキサミド誘導体
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JP2017520610A (ja) 2014-07-17 2017-07-27 シーエイチディーアイ ファウンデーション，インコーポレーテッド Ｈｉｖ関連障害を治療するための方法及び組成物
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WO2005094329A3 (en) 2007-02-08
CN101098697A (zh) 2008-01-02
EP1727542A4 (en) 2009-08-05
CA2557166C (en) 2015-06-30
BRPI0507818A (pt) 2007-07-10
CA2557166A1 (en) 2005-10-13
WO2005094329A2 (en) 2005-10-13
WO2005094329A8 (en) 2006-01-05
US20130225586A1 (en) 2013-08-29
MXPA06010793A (es) 2006-12-19
EP1727542A2 (en) 2006-12-06
AU2005228417A1 (en) 2005-10-13
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