CN101098675B - 稳定的磷酸钙复合物 - Google Patents

稳定的磷酸钙复合物 Download PDF

Info

Publication number
CN101098675B
CN101098675B CN2005800465370A CN200580046537A CN101098675B CN 101098675 B CN101098675 B CN 101098675B CN 2005800465370 A CN2005800465370 A CN 2005800465370A CN 200580046537 A CN200580046537 A CN 200580046537A CN 101098675 B CN101098675 B CN 101098675B
Authority
CN
China
Prior art keywords
complex
solution
calcium
phosphopeptide caseinate
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN2005800465370A
Other languages
English (en)
Chinese (zh)
Other versions
CN101098675A (zh
Inventor
埃里克·查尔斯·雷诺兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Melbourne
Original Assignee
University of Melbourne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2004906762A external-priority patent/AU2004906762A0/en
Application filed by University of Melbourne filed Critical University of Melbourne
Publication of CN101098675A publication Critical patent/CN101098675A/zh
Application granted granted Critical
Publication of CN101098675B publication Critical patent/CN101098675B/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24Phosphorous; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/69Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2005800465370A 2004-11-25 2005-11-24 稳定的磷酸钙复合物 Expired - Lifetime CN101098675B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2004906762A AU2004906762A0 (en) 2004-11-25 Stabilized calcium phosphate complexes
AU2004906762 2004-11-25
PCT/AU2005/001781 WO2006056013A1 (en) 2004-11-25 2005-11-24 Stabilized calcium phosphate complexes

Publications (2)

Publication Number Publication Date
CN101098675A CN101098675A (zh) 2008-01-02
CN101098675B true CN101098675B (zh) 2013-04-10

Family

ID=36497671

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800465370A Expired - Lifetime CN101098675B (zh) 2004-11-25 2005-11-24 稳定的磷酸钙复合物

Country Status (12)

Country Link
US (3) US8609071B2 (https=)
EP (2) EP3192489A1 (https=)
JP (1) JP5000525B2 (https=)
CN (1) CN101098675B (https=)
AU (1) AU2005309327B2 (https=)
BR (1) BRPI0517883B8 (https=)
CA (1) CA2589270C (https=)
MX (1) MX2007006254A (https=)
NZ (1) NZ555335A (https=)
PL (1) PL1827366T3 (https=)
RU (1) RU2404738C2 (https=)
WO (1) WO2006056013A1 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2705826B1 (en) * 2006-02-09 2019-09-11 The University of Melbourne Fluoride composition and methods for dental mineralization
CN101415398B (zh) 2006-04-05 2013-01-09 卡夫食品环球品牌有限责任公司 口腔递送系统中的磷酸钙复合物和盐
AU2007235445B2 (en) 2006-04-05 2011-04-14 Intercontinental Great Brands Llc Calcium phosphate complex in acid containing confectionery
ES2619161T3 (es) 2006-04-05 2017-06-23 Intercontinental Great Brands Llc Complejo de fosfato de calcio y sales en sistemas de suministro oral
CA2965384C (en) 2007-08-09 2021-06-22 The Board Of Regents Of The University Of Texas System Bi-layered bone-like scaffolds
BRPI0915885A2 (pt) * 2008-07-09 2015-11-03 Univ Nebraska micelas funcionais para a liberação direcionada de substâncias químicas em tecido duro
JP2010047494A (ja) * 2008-08-20 2010-03-04 Gc Corp 歯牙塗布用組成物
AU2011250934B2 (en) * 2010-05-11 2016-02-25 Howmedica Osteonics Corp., Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods
US20140161852A1 (en) * 2011-04-20 2014-06-12 University Of Rochester Nanoparticle dental composition and method of making
JP2013163656A (ja) * 2012-02-10 2013-08-22 Gc Corp 歯磨剤
US9744108B2 (en) 2013-02-28 2017-08-29 University Of Tennessee Research Foundation Methods and compositions for preventing and treating tooth erosion
US10314771B2 (en) 2013-02-28 2019-06-11 University Of Tennessee Research Foundation Methods and compositions for preventing and treating tooth erosion
MX378581B (es) * 2013-07-23 2025-03-10 Univ Melbourne Composiciones y metodos para la mineralizacion dental.
WO2015023773A2 (en) 2013-08-14 2015-02-19 University Of Tennessee Research Foundation Tooth remineralization compositions and methods
EP3049054B1 (en) 2013-09-25 2018-04-04 Credentis AG Dental care product for tooth whitening
EP2853256A1 (en) 2013-09-25 2015-04-01 Credentis AG Dental care product for tooth whitening
US9168114B2 (en) 2013-10-17 2015-10-27 B & D Dental Corp. Method of making a dental prosthesis
ES2959412T3 (es) 2013-12-24 2024-02-26 Univ Melbourne Composiciones estañosas estabilizadas
JP6751027B2 (ja) * 2014-07-11 2020-09-02 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 非晶質リン酸カルシウムを供給する口腔ケア処方システム
EP3174409A4 (en) 2014-07-31 2018-01-17 Amorphical Ltd. Encapsulated amorphous calcium carbonate compositions
JP2016102069A (ja) * 2014-11-27 2016-06-02 株式会社ジーシー 歯面清掃方法、歯面清掃用組成物、及びその使用方法
CN107427700A (zh) * 2014-12-24 2017-12-01 墨尔本大学 矿化氟化物组合物
US10219986B2 (en) 2015-03-04 2019-03-05 Modern Ideas LLC Stabilized calcium phosphate and methods of forming same
MX2018005200A (es) * 2015-10-26 2018-07-06 Basf Se Productos para el cuidado bucal y procedimientos que comprenden polipeptidos de union a hidroxiapatita (habp).
US9956314B2 (en) 2016-01-26 2018-05-01 Modern Ideas LLC Adhesive for use with bone and bone-like structures
BR112018074268B1 (pt) 2016-05-26 2022-04-19 3M Innovative Properties Company Pasta dental, kit para tratamento de uma superfície na cavidade oral de um indivíduo, e uso
US12109284B2 (en) 2016-11-08 2024-10-08 Dentherapy Ltd Compositions comprising fluoride and calcium and method for preparing them
EA201991935A1 (ru) 2017-03-14 2020-02-14 Де Юниверсити Оф Мельбурн Комплексы для лечения чувствительности
EA201991933A1 (ru) 2017-03-14 2020-03-05 Де Юниверсити Оф Мельбурн Лечение гингивита
US12569417B2 (en) 2019-03-13 2026-03-10 The University Of Melbourne Compositions and methods for promoting mineralization
JP7546615B2 (ja) * 2019-07-04 2024-09-06 ファートン ホールディング エス.アー. 歯の再石灰化のための組成物
CN110483622B (zh) * 2019-08-26 2021-06-11 无限极(中国)有限公司 酪蛋白磷酸肽及其制备方法、应用
US11154470B1 (en) 2020-07-31 2021-10-26 vVardis AG Anti-inflammatory and senolytic dental care product with tooth whitening characteristics
EP3984517A1 (en) 2020-10-19 2022-04-20 Credentis AG Accelerating tooth remineralisation and bone regeneration with self-assembling peptides and amorphous calcium phosphate
CN112499607B (zh) * 2020-10-29 2022-07-26 南京师范大学 用于多磷酸肽富集及磷酸化位点鉴定的纳米磷酸钙的制备方法及其产品和应用
GB202110114D0 (en) 2021-07-14 2021-08-25 Dentherapy Ltd Oral care compositions for use in treaatment
CN114343060B (zh) * 2021-12-30 2023-07-25 河南金丹乳酸科技股份有限公司 一种乳酸生产中提高菌体渣中蛋白含量的工艺
EP4608356A1 (en) 2022-10-28 2025-09-03 Queen Mary University of London Toothpaste composition

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040406A1 (en) * 1997-03-13 1998-09-17 The University Of Melbourne Calcium phosphopeptide complexes
WO2002094204A1 (en) * 2001-05-21 2002-11-28 The University Of Melbourne Dental restorative materials
WO2003059303A2 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and fluoride
WO2003059304A1 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and flouride
CN1450888A (zh) * 1999-03-25 2003-10-22 沃尼尔·朗伯公司 口腔保健用的口香糖和糖果

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522805A (en) * 1983-06-08 1985-06-11 Norman Gordon Tooth and gum dentifrice
CA1315480C (en) 1986-06-12 1993-03-30 Eric Charles Reynolds Phosphopeptides
US5015628A (en) 1986-06-12 1991-05-14 The University Of Melbourne Anticariogenic phosphopeptides
US6056930A (en) * 1989-05-24 2000-05-02 American Dental Association Health Foundation Methods and compositions for mineralizing and fluoridating calcified tissues
US5227154A (en) 1991-08-22 1993-07-13 The University Of Melbourne Phosphopeptides for the treatment of dental calculus
KR100238551B1 (ko) 1992-06-29 2000-02-01 도우글라스 웨이르 민감성 치아 치료
JP3340265B2 (ja) 1994-11-21 2002-11-05 一枝 山岸 歯の漂白剤
JP4040705B2 (ja) 1996-01-24 2008-01-30 株式会社サンギ 口腔組成物
JP2975337B2 (ja) 1997-02-20 1999-11-10 雪印乳業株式会社 カルシウム複合体
JP3742523B2 (ja) * 1998-02-27 2006-02-08 雪印乳業株式会社 高分子型カルシウム・ホスホペプチド複合体
FR2791573B1 (fr) 1999-03-30 2003-04-11 Pf Medicament Utilisation d'un extrait de serenoa repens pour la fabrication d'un medicament destine au traitement du cancer de la prostate
US6521215B2 (en) * 1999-05-28 2003-02-18 Devin Okay Compositions and methods for tooth treatment
US6685920B2 (en) 1999-11-12 2004-02-03 The Procter & Gamble Company Method of protecting teeth against erosion
GB9929919D0 (en) 1999-12-17 2000-02-09 Hannah Research Inst The Calcium phosphate nanoclusters and their applications
RU2179420C2 (ru) * 2000-05-26 2002-02-20 Иркутский государственный медицинский университет Способ профилактики кариеса зубов
JP2002338447A (ja) 2001-05-15 2002-11-27 Kuraray Co Ltd 歯科用組成物
NZ522071A (en) 2002-10-18 2005-07-29 Patrick Joseph Silcock Hydrolysed casein phosphoprotein preparations for bioactive metal ion delivery and teeth remineralisation
JP4340069B2 (ja) * 2003-01-10 2009-10-07 雪印乳業株式会社 カルシウム複合体の製造法
US20050089481A1 (en) 2003-10-23 2005-04-28 Gc Corporation Composition for caries prevention
US20060183081A1 (en) 2004-09-27 2006-08-17 Al Bevilacqua Tooth bleaching system and method
AR057353A1 (es) 2005-06-07 2007-11-28 Univ Melbourne Mineralizacion dental
AR057402A1 (es) 2005-06-24 2007-12-05 Univ Melbourne Complejos de fosfato de calcio estabilizados por fosfopeptidos o fosfoproteinas, proceso de obtencion y composiciones farmaceuticas

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040406A1 (en) * 1997-03-13 1998-09-17 The University Of Melbourne Calcium phosphopeptide complexes
CN1450888A (zh) * 1999-03-25 2003-10-22 沃尼尔·朗伯公司 口腔保健用的口香糖和糖果
WO2002094204A1 (en) * 2001-05-21 2002-11-28 The University Of Melbourne Dental restorative materials
WO2003059303A2 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and fluoride
WO2003059304A1 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and flouride

Also Published As

Publication number Publication date
AU2005309327B2 (en) 2010-11-25
MX2007006254A (es) 2007-09-07
BRPI0517883B1 (pt) 2015-06-23
US9814662B2 (en) 2017-11-14
EP1827366A1 (en) 2007-09-05
CN101098675A (zh) 2008-01-02
US20140079650A1 (en) 2014-03-20
BRPI0517883A (pt) 2008-10-21
CA2589270C (en) 2014-07-15
AU2005309327A1 (en) 2006-06-01
RU2007123603A (ru) 2008-12-27
NZ555335A (en) 2010-10-29
PL1827366T3 (pl) 2017-10-31
US20080075675A1 (en) 2008-03-27
US8609071B2 (en) 2013-12-17
EP3192489A1 (en) 2017-07-19
US9295628B2 (en) 2016-03-29
JP2008521754A (ja) 2008-06-26
JP5000525B2 (ja) 2012-08-15
US20160175226A1 (en) 2016-06-23
EP1827366A4 (en) 2010-05-26
EP1827366B1 (en) 2017-03-15
BRPI0517883B8 (pt) 2020-03-24
CA2589270A1 (en) 2006-06-01
WO2006056013A1 (en) 2006-06-01
RU2404738C2 (ru) 2010-11-27

Similar Documents

Publication Publication Date Title
CN101098675B (zh) 稳定的磷酸钙复合物
JP5709818B2 (ja) イオン性複合体
JP4541455B2 (ja) カルシウムホスホペプチド複合体
US11564873B2 (en) Stabilized stannous compositions
TWI679991B (zh) 用於牙齒礦化之組成物及方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20130410