CN100548300C - 雷诺嗪在用于制备治疗心律失常药剂中的应用 - Google Patents

雷诺嗪在用于制备治疗心律失常药剂中的应用 Download PDF

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Publication number
CN100548300C
CN100548300C CNB038078716A CN03807871A CN100548300C CN 100548300 C CN100548300 C CN 100548300C CN B038078716 A CNB038078716 A CN B038078716A CN 03807871 A CN03807871 A CN 03807871A CN 100548300 C CN100548300 C CN 100548300C
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ranolazine
arrhythmia
pharmaceutical composition
use according
apd
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Expired - Fee Related
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Chinese (zh)
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CN1646127A (zh
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路易斯·贝拉尔迪内利
查尔斯·安茨叶列维奇
布伦特·布莱克本
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Gilead Sciences Inc
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CV Therapeutics Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CNB038078716A 2002-04-04 2003-04-04 雷诺嗪在用于制备治疗心律失常药剂中的应用 Expired - Fee Related CN100548300C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US37015002P 2002-04-04 2002-04-04
US60/370,150 2002-04-04
US40829202P 2002-09-05 2002-09-05
US60/408,292 2002-09-05
US42258902P 2002-10-30 2002-10-30
US60/422,589 2002-10-30

Related Child Applications (1)

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CN200910171650A Division CN101843619A (zh) 2002-04-04 2003-04-04 雷诺嗪在用于制备治疗心律失常药剂中的应用

Publications (2)

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CN1646127A CN1646127A (zh) 2005-07-27
CN100548300C true CN100548300C (zh) 2009-10-14

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CNB038078716A Expired - Fee Related CN100548300C (zh) 2002-04-04 2003-04-04 雷诺嗪在用于制备治疗心律失常药剂中的应用
CN200910171650A Pending CN101843619A (zh) 2002-04-04 2003-04-04 雷诺嗪在用于制备治疗心律失常药剂中的应用

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US (2) US20030220344A1 (enExample)
EP (3) EP1490066B1 (enExample)
JP (1) JP4608217B2 (enExample)
KR (2) KR20040099395A (enExample)
CN (2) CN100548300C (enExample)
AT (2) ATE397932T1 (enExample)
AU (3) AU2003230810B2 (enExample)
CA (1) CA2481192C (enExample)
CY (1) CY1110400T1 (enExample)
DE (2) DE60332975D1 (enExample)
DK (2) DK1930007T3 (enExample)
ES (2) ES2345573T3 (enExample)
IL (1) IL197406A0 (enExample)
MX (1) MXPA04009637A (enExample)
NO (1) NO330953B1 (enExample)
NZ (1) NZ535610A (enExample)
PT (2) PT1930007E (enExample)
SI (2) SI1930007T1 (enExample)
WO (1) WO2003086401A1 (enExample)

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AU2003248558B8 (en) * 2002-05-21 2009-07-09 Gilead Sciences, Inc. Method of treating diabetes
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
JP2007514769A (ja) * 2003-12-18 2007-06-07 シーブイ・セラピューティクス・インコーポレイテッド １−アルカン−２−オール置換ピペラジンおよびピペリジン化合物
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RU2384332C2 (ru) * 2005-01-06 2010-03-20 Си Ви Терапьютикс, Инк. Фармацевтические препаративные формы замедленного высвобождения
US20060264458A1 (en) * 2005-05-03 2006-11-23 Jie Du Quinine dosage forms and methods of use thereof
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US20090111826A1 (en) * 2007-02-13 2009-04-30 Louis Lange Use of ranolazine for the treatment of cardiovascular diseases
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JP2010518170A (ja) * 2007-02-13 2010-05-27 ギリアード・パロ・アルト・インコーポレイテッド 冠微小血管疾患の処置のためのラノラジンの使用
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KR20100119804A (ko) 2010-11-10
DE60332975D1 (de) 2010-07-22
IL197406A0 (en) 2011-07-31
ATE470445T1 (de) 2010-06-15
DK1490066T3 (da) 2008-10-13
CA2481192C (en) 2012-07-03
SI1930007T1 (sl) 2010-08-31
JP2005528393A (ja) 2005-09-22
CY1110400T1 (el) 2015-04-29
SI1490066T1 (sl) 2008-10-31
US20030220344A1 (en) 2003-11-27
US20100004255A1 (en) 2010-01-07
PT1490066E (pt) 2008-07-22
CN101843619A (zh) 2010-09-29
KR20040099395A (ko) 2004-11-26
AU2003230810B2 (en) 2009-02-26
ATE397932T1 (de) 2008-07-15
ES2304507T3 (es) 2008-10-16
EP1930007A1 (en) 2008-06-11
AU2009201065B2 (en) 2011-07-21
AU2009201065A1 (en) 2009-04-09
CA2481192A1 (en) 2003-10-23
AU2003230810A1 (en) 2003-10-27
HK1120390A1 (en) 2009-04-03
CN1646127A (zh) 2005-07-27
PT1930007E (pt) 2010-08-17
EP1490066B1 (en) 2008-06-11
DK1930007T3 (da) 2010-08-30
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MXPA04009637A (es) 2005-07-14
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