CN100534530C - 用于抗炎化合物局部释放的载体 - Google Patents

用于抗炎化合物局部释放的载体 Download PDF

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Publication number
CN100534530C
CN100534530C CNB031650058A CN03165005A CN100534530C CN 100534530 C CN100534530 C CN 100534530C CN B031650058 A CNB031650058 A CN B031650058A CN 03165005 A CN03165005 A CN 03165005A CN 100534530 C CN100534530 C CN 100534530C
Authority
CN
China
Prior art keywords
camphora
compositions
menthol
isomer
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB031650058A
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English (en)
Chinese (zh)
Other versions
CN1500524A (zh
Inventor
约瑟夫·施瓦茨
迈克尔·韦斯帕皮尔
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UMeWorld
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ALFARIX Inc
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Publication date
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Publication of CN1500524A publication Critical patent/CN1500524A/zh
Application granted granted Critical
Publication of CN100534530C publication Critical patent/CN100534530C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNB031650058A 2002-09-27 2003-09-27 用于抗炎化合物局部释放的载体 Expired - Fee Related CN100534530C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/255,951 US7138394B2 (en) 2002-09-27 2002-09-27 Vehicle for topical delivery of anti-inflammatory compounds
US10/255,951 2002-09-27

Publications (2)

Publication Number Publication Date
CN1500524A CN1500524A (zh) 2004-06-02
CN100534530C true CN100534530C (zh) 2009-09-02

Family

ID=32029201

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB031650058A Expired - Fee Related CN100534530C (zh) 2002-09-27 2003-09-27 用于抗炎化合物局部释放的载体

Country Status (4)

Country Link
US (3) US7138394B2 (enExample)
JP (1) JP2004115525A (enExample)
CN (1) CN100534530C (enExample)
MX (1) MXPA03008947A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105324130A (zh) * 2013-02-01 2016-02-10 D滴公司 液体薄荷醇组合物

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US7138394B2 (en) * 2002-09-27 2006-11-21 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
US20060241175A1 (en) * 2002-09-27 2006-10-26 Joseph Schwarz Vehicle for topical delivery of anti-inflammatory compounds
EP1858556A1 (en) * 2005-03-16 2007-11-28 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
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WO2006117516A2 (en) * 2005-05-05 2006-11-09 Reckitt Benckiser Inc Topical compositions
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US20070048360A1 (en) * 2005-08-23 2007-03-01 R Carrara Dario N Pharmaceutical compositions with melting point depressant agents and method of making same
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AU2006330526B2 (en) * 2005-12-22 2012-09-27 Oakwood Laboratories, Llc Sublimable sustained release delivery system and method of making same
JP5028885B2 (ja) * 2006-07-04 2012-09-19 大正製薬株式会社 ユビデカレノン含有自己乳化組成物
DE102006042742A1 (de) * 2006-09-12 2008-03-27 Barnikol-Keuten, Doris, Dr. Nano-Vehikel für den transkutanen Transport, diese enthaltende Zubereitungen und deren Anwendung
CA2666398C (en) 2006-10-17 2015-08-18 Ed Kisak Diclofenac gel
HU227970B1 (en) * 2007-07-10 2012-07-30 Egis Gyogyszergyar Nyrt Pharmaceutical compositions containing silicones of high volatility
US8618164B2 (en) 2009-03-31 2013-12-31 Nuvo Research Inc. Treatment of pain with topical diclofenac compounds
CN101524325B (zh) * 2009-04-03 2010-12-29 龚志成 复方薄荷脑微乳及其鼻用制剂
AU2010233343A1 (en) * 2009-04-08 2011-10-27 Cadila Healthcare Limited Stable pharmaceutical compositions of diclofenac
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DE102010013064A1 (de) 2010-03-26 2011-12-15 Gabriele Blume Neuartiges Trägersystem für den Transport von Wirkstoffen in die Haut
EP2457554A1 (de) * 2010-11-24 2012-05-30 Symrise AG Menthol enthaltende Mischung
US9545429B1 (en) 2011-09-03 2017-01-17 Biolyte Laboratories, Llc Homeopathic formulations
US10045935B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US11154535B2 (en) 2012-07-31 2021-10-26 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US10045965B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
FR2994386B1 (fr) * 2012-08-07 2016-06-24 Thorel Jean-Noel Inhibition de l'adhesion de micro-organismes pathogenes par un ester de saccharose et/ou de sorbitan dans le traitement cosmetique de l'atopie cutanee
CN104884034B (zh) * 2012-12-20 2017-06-06 荷兰联合利华有限公司 个人护理组合物中的低共熔混合物
CN104918597B (zh) 2012-12-20 2017-08-11 荷兰联合利华有限公司 个人护理组合物中的低共熔混合物
WO2014127458A1 (en) * 2013-02-22 2014-08-28 Eastgate Pharmaceuticals Inc. Pharmaceutical composition for transmucosal administration of benzodiazepines
EP3113764B1 (en) * 2014-03-04 2020-07-22 Eastgate Pharmaceuticals Inc. Pharmaceutical composition for transmucosal delivery and methods for treating diabetes in a subject in need thereof
JP6599083B2 (ja) * 2014-03-30 2019-10-30 小林製薬株式会社 外用医薬組成物
JP6580305B2 (ja) * 2014-03-30 2019-09-25 小林製薬株式会社 外用医薬組成物
US9012402B1 (en) 2014-06-11 2015-04-21 James Blanchard Gel for topical delivery of NSAIDs to provide relief of musculoskeletal pain and methods for its preparation
US9623062B2 (en) * 2014-06-27 2017-04-18 Jeju National University Industryacademic Cooperation Foundation Anti-ageing activity of camphor in fibroblast cell line
US10828251B1 (en) 2017-01-14 2020-11-10 Biolyte Laboratories, Llc Homeopathic formulations
US10617634B1 (en) 2017-03-10 2020-04-14 Biolyte Laboratories, Llc Topical homeopathic formulations for menstrual cramps
US10821075B1 (en) 2017-07-12 2020-11-03 James Blanchard Compositions for topical application of a medicaments onto a mammalian body surface
PY1956418A (es) * 2018-07-13 2021-02-26 Upl Ltd Composición que comprende mezcla eutéctica de boscalid y un fungicida de strobilurin
JP2021533192A (ja) * 2018-08-01 2021-12-02 ノビラ・ファーマシューティカルズ・インコーポレイテッドNovilla Pharmaceuticals, Inc. 薬剤を含む共晶溶媒、並びにその製造および使用方法
FR3085849B1 (fr) * 2018-09-17 2021-01-01 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Composition pharmaceutique a usage topique comprenant au moins une substance anti-inflammatoire
WO2020079706A1 (en) 2018-10-15 2020-04-23 Cipla Limited Pharmaceutical formulation
EP3941447B1 (en) * 2019-03-21 2025-05-07 Universidade Nova De Lisboa Eutectic composition comprising a nonsteroidal anti-inflammatory drug and a terpene for use in the treatment of cancer
WO2020223093A1 (en) * 2019-04-30 2020-11-05 Bayer Healthcare Llc Topical analgesic gel compositions
FR3099697B1 (fr) * 2019-08-09 2022-07-08 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Composition pharmaceutique à usage topique se présentant sous la forme d’une phase dispersée à base d’au moins un diol court dans une phase grasse continue et comprenant au moins une substance anti-inflammatoire.
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CN118084849B (zh) 2024-01-22 2024-07-19 南京默可思泰医药科技有限公司 一种含有麝香草酚及其衍生物的胶束制剂的制备方法和应用
CN118490546B (zh) * 2024-05-11 2026-07-17 广州卓芬化妆品有限公司 一种祛痘组合物、祛痘修复纳米产品及其制备方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105324130A (zh) * 2013-02-01 2016-02-10 D滴公司 液体薄荷醇组合物

Also Published As

Publication number Publication date
US20040063794A1 (en) 2004-04-01
US7781429B2 (en) 2010-08-24
MXPA03008947A (es) 2005-04-19
JP2004115525A (ja) 2004-04-15
US20050158348A1 (en) 2005-07-21
US20060211688A1 (en) 2006-09-21
CN1500524A (zh) 2004-06-02
US7138394B2 (en) 2006-11-21

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Owner name: UME WORLD LIMITED

Free format text: FORMER NAME: ALFARIX INC.

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