FR3085849B1 - Composition pharmaceutique a usage topique comprenant au moins une substance anti-inflammatoire - Google Patents
Composition pharmaceutique a usage topique comprenant au moins une substance anti-inflammatoire Download PDFInfo
- Publication number
- FR3085849B1 FR3085849B1 FR1858341A FR1858341A FR3085849B1 FR 3085849 B1 FR3085849 B1 FR 3085849B1 FR 1858341 A FR1858341 A FR 1858341A FR 1858341 A FR1858341 A FR 1858341A FR 3085849 B1 FR3085849 B1 FR 3085849B1
- Authority
- FR
- France
- Prior art keywords
- pharmaceutical composition
- topical use
- inflammatory substance
- mass
- polyhydroxystearates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 229920000223 polyglycerol Polymers 0.000 abstract 4
- 230000001804 emulsifying effect Effects 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000003921 oil Substances 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000002191 fatty alcohols Chemical class 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 229920000151 polyglycol Polymers 0.000 abstract 1
- 239000010695 polyglycol Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Composition pharmaceutique à usage topique se présentant sous la forme d'une émulsion de type eau dans huile comprenant pour 100% de sa masse : - de 60% à 80% massique d'une phase aqueuse gélifiée (A1) comprenant une substance inflammatoire, - de 20% à 40% massique d'une phase grasse (A2) comprenant au moins une huile et un système émulsionnant comprenant une combinaison d'au moins un agent tensioactif émulsionnant (Si) sélectionné parmi les éléments du groupe constitué par les compositions d'alkylpolyglycosides, les compositions d'alkylpolyglycosides et d'alcools gras, et d'au moins un agent tensioactif émulsionnant (S2) sélectionné parmi les éléments du groupe constitué par les esters de polyglycérols, les esters de polyglycérols alcoxylés, les polyhydroxystéarates de polyglycols, les polyhydroxystéarates de polyglycérols, les polyhydroxystéarates de polyglycérols alcoxylés.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1858341A FR3085849B1 (fr) | 2018-09-17 | 2018-09-17 | Composition pharmaceutique a usage topique comprenant au moins une substance anti-inflammatoire |
JP2021514330A JP2022500446A (ja) | 2018-09-17 | 2019-09-12 | 少なくとも1つの抗炎症物質を含む局所使用のための医薬組成物 |
US17/276,693 US20220023208A1 (en) | 2018-09-17 | 2019-09-12 | Pharmaceutical composition for topical use comprising at least one antiinflammatory substance |
PCT/FR2019/052116 WO2020058603A1 (fr) | 2018-09-17 | 2019-09-12 | Composition pharmaceutique à usage topique comprenant au moins une substance anti-inflammatoire |
CN201980060301.4A CN112739326A (zh) | 2018-09-17 | 2019-09-12 | 包含至少一种抗炎物质的用于局部使用的药物组合物 |
EP19787033.0A EP3852726A1 (fr) | 2018-09-17 | 2019-09-12 | Composition pharmaceutique à usage topique comprenant au moins une substance anti-inflammatoire |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1858341A FR3085849B1 (fr) | 2018-09-17 | 2018-09-17 | Composition pharmaceutique a usage topique comprenant au moins une substance anti-inflammatoire |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3085849A1 FR3085849A1 (fr) | 2020-03-20 |
FR3085849B1 true FR3085849B1 (fr) | 2021-01-01 |
Family
ID=65201466
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1858341A Active FR3085849B1 (fr) | 2018-09-17 | 2018-09-17 | Composition pharmaceutique a usage topique comprenant au moins une substance anti-inflammatoire |
Country Status (6)
Country | Link |
---|---|
US (1) | US20220023208A1 (fr) |
EP (1) | EP3852726A1 (fr) |
JP (1) | JP2022500446A (fr) |
CN (1) | CN112739326A (fr) |
FR (1) | FR3085849B1 (fr) |
WO (1) | WO2020058603A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3118578B1 (fr) * | 2021-01-07 | 2024-03-08 | Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic | Composition pharmaceutique comprenant comme agent épaississant une composition qui présente des propriétés épaississantes de milieux polaires |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4720353A (en) * | 1987-04-14 | 1988-01-19 | Richardson-Vicks Inc. | Stable pharmaceutical w/o emulsion composition |
FR2721607B1 (fr) | 1994-06-28 | 1996-10-31 | Seppic Sa | Nouveaux dérivés d'ammoniums quaternaires, leur procédé de préparation et leur utilisation comme agents de surface. |
JP2001181166A (ja) * | 1999-12-22 | 2001-07-03 | Lion Corp | 油中水型乳化皮膚外用剤組成物 |
US7138394B2 (en) * | 2002-09-27 | 2006-11-21 | Alpharx Inc. | Vehicle for topical delivery of anti-inflammatory compounds |
US20060241175A1 (en) * | 2002-09-27 | 2006-10-26 | Joseph Schwarz | Vehicle for topical delivery of anti-inflammatory compounds |
FR2852257B1 (fr) * | 2003-03-14 | 2006-07-21 | Emulsions eau-dans-huile, a forte teneur en phase aqueuse, obtenues par un procede simple et economique | |
FR2852258B1 (fr) * | 2003-03-14 | 2006-07-21 | Emulsions notamment solaires de type eau-dans-huile, et leur procede de preparation | |
AU2004313285A1 (en) * | 2003-12-16 | 2005-09-29 | Foamix Ltd | Oleaginous pharmaceutical and cosmetic foam |
FR2898499B1 (fr) * | 2006-03-15 | 2008-11-28 | Galderma Sa | Nouvelles compositions topiques sous forme d'emulsion h/e comprenant un glycol pro-penetrant |
FR2912651A1 (fr) | 2007-02-21 | 2008-08-22 | Oreal | Emulsion e/h pour le soin de la peau. |
CN101888776B (zh) * | 2007-09-20 | 2015-03-11 | 罗切斯特大学 | 治疗或预防炎性病症的方法和组合物 |
GB0818473D0 (en) * | 2008-10-08 | 2008-11-12 | Probio Nutraceuticals As | Composition |
FR2950060B1 (fr) * | 2009-09-11 | 2011-10-28 | Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic | Nouveau polymere en poudre, procede pour sa preparation et utilisation comme epaississant |
JP5769481B2 (ja) * | 2011-04-15 | 2015-08-26 | 株式会社 資生堂 | ウフェナマート含有皮膚外用剤 |
FR3004454B1 (fr) * | 2013-04-12 | 2015-03-27 | Seppic Sa | Nouvelles emulsions eau-dans-huile a forte teneur en phase aqueuse, de consistances liquides et stables au stockage |
-
2018
- 2018-09-17 FR FR1858341A patent/FR3085849B1/fr active Active
-
2019
- 2019-09-12 WO PCT/FR2019/052116 patent/WO2020058603A1/fr unknown
- 2019-09-12 JP JP2021514330A patent/JP2022500446A/ja active Pending
- 2019-09-12 CN CN201980060301.4A patent/CN112739326A/zh active Pending
- 2019-09-12 US US17/276,693 patent/US20220023208A1/en active Pending
- 2019-09-12 EP EP19787033.0A patent/EP3852726A1/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
FR3085849A1 (fr) | 2020-03-20 |
WO2020058603A1 (fr) | 2020-03-26 |
EP3852726A1 (fr) | 2021-07-28 |
CN112739326A (zh) | 2021-04-30 |
US20220023208A1 (en) | 2022-01-27 |
JP2022500446A (ja) | 2022-01-04 |
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Year of fee payment: 2 |
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Effective date: 20200320 |
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PLFP | Fee payment |
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