CN100492010C - 生物传感器 - Google Patents

生物传感器 Download PDF

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Publication number
CN100492010C
CN100492010C CNB2003801015042A CN200380101504A CN100492010C CN 100492010 C CN100492010 C CN 100492010C CN B2003801015042 A CNB2003801015042 A CN B2003801015042A CN 200380101504 A CN200380101504 A CN 200380101504A CN 100492010 C CN100492010 C CN 100492010C
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CN
China
Prior art keywords
solution
biology sensor
examined
glucose
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB2003801015042A
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English (en)
Chinese (zh)
Other versions
CN1705882A (zh
Inventor
霍姆·W·黑林格
洛伦·L·鲁格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
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Duke University
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Filing date
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Application filed by Duke University filed Critical Duke University
Publication of CN1705882A publication Critical patent/CN1705882A/zh
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Publication of CN100492010C publication Critical patent/CN100492010C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Holo Graphy (AREA)
CNB2003801015042A 2002-10-16 2003-10-16 生物传感器 Expired - Fee Related CN100492010C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41835902P 2002-10-16 2002-10-16
US60/418,359 2002-10-16

Publications (2)

Publication Number Publication Date
CN1705882A CN1705882A (zh) 2005-12-07
CN100492010C true CN100492010C (zh) 2009-05-27

Family

ID=32107920

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2003801015042A Expired - Fee Related CN100492010C (zh) 2002-10-16 2003-10-16 生物传感器

Country Status (13)

Country Link
US (3) US9625458B2 (US20080166747A1-20080710-P00010.png)
EP (1) EP1552303B1 (US20080166747A1-20080710-P00010.png)
JP (1) JP4571499B2 (US20080166747A1-20080710-P00010.png)
KR (1) KR101107630B1 (US20080166747A1-20080710-P00010.png)
CN (1) CN100492010C (US20080166747A1-20080710-P00010.png)
AT (1) ATE423318T1 (US20080166747A1-20080710-P00010.png)
AU (1) AU2003277377B2 (US20080166747A1-20080710-P00010.png)
CA (1) CA2502272C (US20080166747A1-20080710-P00010.png)
DE (1) DE60326256D1 (US20080166747A1-20080710-P00010.png)
DK (1) DK1552303T3 (US20080166747A1-20080710-P00010.png)
ES (1) ES2321931T3 (US20080166747A1-20080710-P00010.png)
HK (1) HK1080937A1 (US20080166747A1-20080710-P00010.png)
WO (1) WO2004036176A2 (US20080166747A1-20080710-P00010.png)

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ES2321931T3 (es) 2002-10-16 2009-06-15 Duke University Biosensores para detectar glucosa.
WO2005007806A2 (en) * 2003-05-07 2005-01-27 Duke University Protein design for receptor-ligand recognition and binding
PL1642117T3 (pl) * 2003-06-20 2018-11-30 F.Hoffmann-La Roche Ag Pasek odczynnika do paska testowego
EP1642124B1 (en) * 2003-06-20 2017-11-29 Roche Diabetes Care GmbH Electrochemical biosensors
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
US20050112685A1 (en) * 2003-11-26 2005-05-26 Amiss Terry J. Compositions and methods for measuring analyte concentrations
US20050181141A1 (en) * 2004-02-18 2005-08-18 Aiden Flanagan Laser-induced explosive vaporization coating method, associated system, and device made by the method
US20050181116A1 (en) * 2004-02-18 2005-08-18 Rob Worsham Method for coating a medical device using a matrix assisted pulsed-laser evaporation technique and associated system and medical device
US20050188921A1 (en) * 2004-02-27 2005-09-01 Anthony Malone Matrix assisted pulsed-laser evaporation technique for coating a medical device and associated system and medical device
US7563891B2 (en) * 2004-05-21 2009-07-21 Becton, Dickinson & Company Long wavelength thiol-reactive fluorophores
WO2006044612A2 (en) * 2004-10-14 2006-04-27 Carnegie Institution Of Washington Development of sensitive fret sensors and methods of using the same
US7777016B2 (en) * 2004-10-14 2010-08-17 Carnegie Institution Of Washington Neurotransmitter sensors and methods of using the same
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
US20090178149A1 (en) * 2005-03-03 2009-07-09 Sylvie Lalonde Polyamine Sensors and Methods of Using the Same
AU2005328651A1 (en) * 2005-03-04 2006-09-14 Carnegie Institution Of Washington Environmentally stable sensors and methods of using the same
US20070154947A1 (en) * 2005-08-31 2007-07-05 The Trustees Of Princeton University Chemical biodiscriminator
ATE489397T1 (de) * 2005-10-14 2010-12-15 Carnegie Inst Of Washington Saccharose-biosensoren und verwendungsverfahren dafür
ATE481412T1 (de) * 2005-10-14 2010-10-15 Carnegie Inst Of Washington Phosphat-biosensoren und verfahren zu deren anwendung
CA2627545A1 (en) * 2005-11-16 2007-05-24 Carnegie Institution Of Washington Multimeric biosensors and methods of using the same
WO2008131360A1 (en) 2007-04-20 2008-10-30 Becton, Dickinson And Company Hydrogel compositions
EP2150586B1 (en) * 2007-05-22 2018-03-14 Becton, Dickinson and Company Dyes having ratiometric fluorescence response for detecting metabolites
US8129532B2 (en) * 2007-08-03 2012-03-06 The University Of Connecticut Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use
WO2009021039A1 (en) * 2007-08-06 2009-02-12 University Of Kentucky Research Foundation Device for detection of molecules of interest
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
US9719992B2 (en) 2011-10-07 2017-08-01 Howard Hughes Medical Institute Genetically encoded biosensors
US10684282B2 (en) 2011-10-07 2020-06-16 Howard Hughes Medical Institute Genetically encoded biosensors
US10466247B2 (en) 2012-11-20 2019-11-05 Becton, Dickinson And Company System and method for diagnosing sensor performance using analyte-independent ratiometric signals
US20140212987A1 (en) * 2013-01-30 2014-07-31 Siemens Healthcare Diagnostics Inc. Signal Ratio in Assay Calibrators
KR101455244B1 (ko) 2013-02-04 2014-10-31 경희대학교 산학협력단 Afm과 탐침형 센서를 이용한 세포독성의 정량적 평가시스템 및 방법
CN105683210B (zh) 2013-08-23 2020-07-14 贝林格尔·英格海姆Rcv两合公司 用于细胞破碎和/或回收生物分子的微粒
US10379125B2 (en) 2013-12-27 2019-08-13 Becton, Dickinson And Company System and method for dynamically calibrating and measuring analyte concentration in diabetes management monitors
EP3362468A4 (en) 2015-10-13 2018-08-22 The Research Foundation for the State University of New York Cleavable fusion tag for protein overexpression and purification
EP3377643A4 (en) 2015-11-20 2019-10-02 Duke University GLUCOSE Biosensor and uses thereof
EP3377899A4 (en) 2015-11-20 2019-10-02 Duke University BICARBONATE BIOSENSORS, CALCIUM BIOSENSORS AND USES THEREOF
WO2017087916A2 (en) 2015-11-20 2017-05-26 Duke University Thermostable glucose biosensors and uses thereof
US11099176B2 (en) 2015-11-20 2021-08-24 Duke University Lactate biosensors and uses thereof
EP3377904B1 (en) 2015-11-20 2024-05-01 Duke University Urea biosensors and uses thereof
GB201714478D0 (en) * 2017-09-08 2017-10-25 Univ Bristol Sensor
WO2021022245A1 (en) * 2019-08-01 2021-02-04 The Trustees Of Indiana University Glyphosate biosensor
CN113980992B (zh) * 2021-12-29 2022-03-25 中国科学院天津工业生物技术研究所 一种l-半胱氨酸生物传感器及其应用

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SE9301270D0 (sv) * 1993-04-19 1993-04-17 Biosensor
KR100259761B1 (ko) 1996-03-15 2000-07-01 타이도 나오카타 에스에이치기 표지용시약, 그의 제조방법 및 이를 이용한 표지법
US6130037A (en) * 1996-04-25 2000-10-10 Pence And Mcgill University Biosensor device and method
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AU7715898A (en) 1997-05-27 1998-12-30 Duke University Synthetic metalloproteins and method of preparation thereof
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ES2321931T3 (es) 2002-10-16 2009-06-15 Duke University Biosensores para detectar glucosa.
WO2005007806A2 (en) 2003-05-07 2005-01-27 Duke University Protein design for receptor-ligand recognition and binding
EP2150586B1 (en) * 2007-05-22 2018-03-14 Becton, Dickinson and Company Dyes having ratiometric fluorescence response for detecting metabolites
WO2008154332A1 (en) * 2007-06-06 2008-12-18 Becton, Dickinson And Company Near-infrared dyes as surface enhanced raman scattering reporters
US9023661B2 (en) * 2007-10-18 2015-05-05 Becton, Dickinson And Company Visual glucose sensor and methods of use thereof

Also Published As

Publication number Publication date
DK1552303T3 (da) 2009-05-25
US20080166747A1 (en) 2008-07-10
US10712341B2 (en) 2020-07-14
KR20050083772A (ko) 2005-08-26
ATE423318T1 (de) 2009-03-15
EP1552303A2 (en) 2005-07-13
US20170322209A1 (en) 2017-11-09
US20040118681A1 (en) 2004-06-24
HK1080937A1 (en) 2006-05-04
EP1552303B1 (en) 2009-02-18
EP1552303A4 (en) 2006-12-27
US9625458B2 (en) 2017-04-18
CN1705882A (zh) 2005-12-07
DE60326256D1 (de) 2009-04-02
WO2004036176A2 (en) 2004-04-29
CA2502272A1 (en) 2004-04-29
AU2003277377B2 (en) 2009-05-21
CA2502272C (en) 2011-10-11
JP4571499B2 (ja) 2010-10-27
KR101107630B1 (ko) 2012-01-25
AU2003277377A1 (en) 2004-05-04
JP2006503293A (ja) 2006-01-26
ES2321931T3 (es) 2009-06-15
WO2004036176A3 (en) 2004-07-29

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