ATE423318T1 - Biosensor zum nachweis von glukose - Google Patents

Biosensor zum nachweis von glukose

Info

Publication number
ATE423318T1
ATE423318T1 AT03809022T AT03809022T ATE423318T1 AT E423318 T1 ATE423318 T1 AT E423318T1 AT 03809022 T AT03809022 T AT 03809022T AT 03809022 T AT03809022 T AT 03809022T AT E423318 T1 ATE423318 T1 AT E423318T1
Authority
AT
Austria
Prior art keywords
biosensor
detecting glucose
covalently
reporter group
bpbp
Prior art date
Application number
AT03809022T
Other languages
English (en)
Inventor
Homme Hellinga
Loren Looger
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Application granted granted Critical
Publication of ATE423318T1 publication Critical patent/ATE423318T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Holo Graphy (AREA)
AT03809022T 2002-10-16 2003-10-16 Biosensor zum nachweis von glukose ATE423318T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41835902P 2002-10-16 2002-10-16

Publications (1)

Publication Number Publication Date
ATE423318T1 true ATE423318T1 (de) 2009-03-15

Family

ID=32107920

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03809022T ATE423318T1 (de) 2002-10-16 2003-10-16 Biosensor zum nachweis von glukose

Country Status (12)

Country Link
US (3) US9625458B2 (de)
EP (1) EP1552303B1 (de)
JP (1) JP4571499B2 (de)
KR (1) KR101107630B1 (de)
CN (1) CN100492010C (de)
AT (1) ATE423318T1 (de)
AU (1) AU2003277377B2 (de)
CA (1) CA2502272C (de)
DE (1) DE60326256D1 (de)
DK (1) DK1552303T3 (de)
ES (1) ES2321931T3 (de)
WO (1) WO2004036176A2 (de)

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KR100627206B1 (ko) * 1998-07-30 2006-09-25 유니챰 가부시키가이샤 박형 내용물용 용기
DE60326256D1 (de) 2002-10-16 2009-04-02 Univ Duke Biosensor zum nachweis von glukose
EP1620548A2 (de) * 2003-05-07 2006-02-01 Duke University Proteinkonstruktion für rezeptor-liganden-erkennung und -bindung
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
KR20070100362A (ko) * 2003-06-20 2007-10-10 에프. 호프만-라 로슈 아게 전기화학 바이오센서에 관한 장치 및 방법
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
JP4447009B2 (ja) 2003-06-20 2010-04-07 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト スロットベント開口を有するテストストリップ
US20050112685A1 (en) * 2003-11-26 2005-05-26 Amiss Terry J. Compositions and methods for measuring analyte concentrations
US20050181116A1 (en) * 2004-02-18 2005-08-18 Rob Worsham Method for coating a medical device using a matrix assisted pulsed-laser evaporation technique and associated system and medical device
US20050181141A1 (en) * 2004-02-18 2005-08-18 Aiden Flanagan Laser-induced explosive vaporization coating method, associated system, and device made by the method
US20050188921A1 (en) * 2004-02-27 2005-09-01 Anthony Malone Matrix assisted pulsed-laser evaporation technique for coating a medical device and associated system and medical device
US7563891B2 (en) * 2004-05-21 2009-07-21 Becton, Dickinson & Company Long wavelength thiol-reactive fluorophores
US8530633B2 (en) * 2004-10-14 2013-09-10 Carnegie Institution Of Washington Development of sensitive FRET sensors and methods of using the same
CA2584116A1 (en) 2004-10-14 2006-04-27 Carnegie Institution Of Washington Neurotransmitter sensors and methods of using the same
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
WO2006096213A1 (en) * 2005-03-03 2006-09-14 Carnegie Institution Of Washington Polyamine sensors and methods of using the same
JP5161588B2 (ja) * 2005-03-04 2013-03-13 カーネギー インスチチューション オブ ワシントン 環境的に安定なセンサおよびそれを使用する方法
US20070154947A1 (en) * 2005-08-31 2007-07-05 The Trustees Of Princeton University Chemical biodiscriminator
DE602005025043D1 (de) * 2005-10-14 2011-01-05 Carnegie Inst Of Washington Saccharose-biosensoren und verwendungsverfahren dafür
AU2005337168B2 (en) * 2005-10-14 2012-07-05 Carnegie Institution Of Washington Phosphate biosensors and methods of using the same
US20080311047A1 (en) * 2005-11-16 2008-12-18 Thijs Kaper Multimetric Biosensors and Methods of Using Same
EP2191007B1 (de) 2007-04-20 2019-06-05 Becton, Dickinson and Company Hydrogelzusammensetzungen
EP2150586B1 (de) * 2007-05-22 2018-03-14 Becton, Dickinson and Company Farbstoffe mti ratiometrischer fluoreszenzreaktion für den nachweis von metaboliten
US8129532B2 (en) * 2007-08-03 2012-03-06 The University Of Connecticut Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use
WO2009021052A1 (en) * 2007-08-06 2009-02-12 University Of Kentucky Research Foundation Polypeptides, systems, and methods useful for detecting glucose
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
US9719992B2 (en) * 2011-10-07 2017-08-01 Howard Hughes Medical Institute Genetically encoded biosensors
US10684282B2 (en) 2011-10-07 2020-06-16 Howard Hughes Medical Institute Genetically encoded biosensors
US10466247B2 (en) 2012-11-20 2019-11-05 Becton, Dickinson And Company System and method for diagnosing sensor performance using analyte-independent ratiometric signals
US20140212987A1 (en) * 2013-01-30 2014-07-31 Siemens Healthcare Diagnostics Inc. Signal Ratio in Assay Calibrators
KR101455244B1 (ko) 2013-02-04 2014-10-31 경희대학교 산학협력단 Afm과 탐침형 센서를 이용한 세포독성의 정량적 평가시스템 및 방법
SG10201801371PA (en) * 2013-08-23 2018-04-27 Boehringer Ingelheim Rcv Gmbh Microparticles for cell disruption and/or biomolecule recovery
US10379125B2 (en) 2013-12-27 2019-08-13 Becton, Dickinson And Company System and method for dynamically calibrating and measuring analyte concentration in diabetes management monitors
WO2017066441A1 (en) * 2015-10-13 2017-04-20 The Research Foundation For The State University Of New York Cleavable fusion tag for protein overexpression and purification
WO2017087915A1 (en) 2015-11-20 2017-05-26 Duke University Lactate biosensors and uses thereof
WO2017087916A2 (en) 2015-11-20 2017-05-26 Duke University Thermostable glucose biosensors and uses thereof
US11906524B2 (en) 2015-11-20 2024-02-20 Duke University Urea biosensors and uses thereof
US11852637B2 (en) 2015-11-20 2023-12-26 Duke University Bicarbonate biosensors, calcium biosensors, and uses thereof
EP3377643A4 (de) * 2015-11-20 2019-10-02 Duke University Glucosebiosensor und verwendungen davon
GB201714478D0 (en) * 2017-09-08 2017-10-25 Univ Bristol Sensor
WO2021022245A1 (en) * 2019-08-01 2021-02-04 The Trustees Of Indiana University Glyphosate biosensor
CN113980992B (zh) * 2021-12-29 2022-03-25 中国科学院天津工业生物技术研究所 一种l-半胱氨酸生物传感器及其应用
KR102731612B1 (ko) * 2022-05-31 2024-11-22 한국과학기술연구원 분할된 글루타민 결합 단백질을 이용한 글루타민 검출용 센서 및 이의 용도

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EP0844246A4 (de) 1996-03-15 1999-06-02 Ss Pharmaceutical Co Reagenzien zur markierung von sh-gruppen, verfahren zu ihrer herstellung und methode zur markierung mit diesen reagenzien
US6130037A (en) 1996-04-25 2000-10-10 Pence And Mcgill University Biosensor device and method
SE9602545L (sv) 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
AU7715898A (en) 1997-05-27 1998-12-30 Duke University Synthetic metalloproteins and method of preparation thereof
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US6013459A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
EP1044374B1 (de) 1997-12-31 2008-10-08 Duke University Glukosebiosensor
US6475733B1 (en) 1998-04-06 2002-11-05 Lerner Pharmaceuticals, Inc. Cell surface receptors for the detection and identification of compounds
IL124903A0 (en) 1998-06-15 1999-01-26 Bauer Alan Josef An enzyme biosensor
EP1098658B1 (de) 1998-07-17 2009-07-08 University of Maryland, Baltimore Manipulierte proteine zum analyten nachweis
US6663862B1 (en) 1999-06-04 2003-12-16 Duke University Reagents for detection and purification of antibody fragments
GB9923146D0 (en) * 1999-09-30 1999-12-01 Imperial College Detector array
WO2003021247A1 (en) 2001-08-28 2003-03-13 Duke University Biosensor
US6855556B2 (en) * 2002-01-04 2005-02-15 Becton, Dickinson And Company Binding protein as biosensors
DE60326256D1 (de) 2002-10-16 2009-04-02 Univ Duke Biosensor zum nachweis von glukose
EP1620548A2 (de) 2003-05-07 2006-02-01 Duke University Proteinkonstruktion für rezeptor-liganden-erkennung und -bindung
EP2150586B1 (de) 2007-05-22 2018-03-14 Becton, Dickinson and Company Farbstoffe mti ratiometrischer fluoreszenzreaktion für den nachweis von metaboliten
EP2152319B1 (de) 2007-06-06 2015-04-08 Becton Dickinson and Company Farbstoffe im nahen infrarotbereich als oberflächenverstärkte raman-scatter-reporter
US9023661B2 (en) 2007-10-18 2015-05-05 Becton, Dickinson And Company Visual glucose sensor and methods of use thereof

Also Published As

Publication number Publication date
DE60326256D1 (de) 2009-04-02
CN1705882A (zh) 2005-12-07
CA2502272A1 (en) 2004-04-29
KR101107630B1 (ko) 2012-01-25
US9625458B2 (en) 2017-04-18
US20040118681A1 (en) 2004-06-24
ES2321931T3 (es) 2009-06-15
CN100492010C (zh) 2009-05-27
US20080166747A1 (en) 2008-07-10
KR20050083772A (ko) 2005-08-26
DK1552303T3 (da) 2009-05-25
EP1552303A4 (de) 2006-12-27
AU2003277377A1 (en) 2004-05-04
US10712341B2 (en) 2020-07-14
EP1552303B1 (de) 2009-02-18
JP2006503293A (ja) 2006-01-26
HK1080937A1 (zh) 2006-05-04
WO2004036176A2 (en) 2004-04-29
US20170322209A1 (en) 2017-11-09
AU2003277377B2 (en) 2009-05-21
EP1552303A2 (de) 2005-07-13
WO2004036176A3 (en) 2004-07-29
CA2502272C (en) 2011-10-11
JP4571499B2 (ja) 2010-10-27

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