ATE532830T1 - Langwellige thiolgruppenreaktive fluorophore - Google Patents
Langwellige thiolgruppenreaktive fluorophoreInfo
- Publication number
- ATE532830T1 ATE532830T1 AT10163379T AT10163379T ATE532830T1 AT E532830 T1 ATE532830 T1 AT E532830T1 AT 10163379 T AT10163379 T AT 10163379T AT 10163379 T AT10163379 T AT 10163379T AT E532830 T1 ATE532830 T1 AT E532830T1
- Authority
- AT
- Austria
- Prior art keywords
- thiol group
- long wave
- group reactive
- reactive fluorophores
- fluorophores
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/10—The polymethine chain containing an even number of >CH- groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/10—The polymethine chain containing an even number of >CH- groups
- C09B23/105—The polymethine chain containing an even number of >CH- groups two >CH- groups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Diabetes (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57394404P | 2004-05-21 | 2004-05-21 | |
US59951404P | 2004-08-06 | 2004-08-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE532830T1 true ATE532830T1 (de) | 2011-11-15 |
Family
ID=35788237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT10163379T ATE532830T1 (de) | 2004-05-21 | 2005-05-20 | Langwellige thiolgruppenreaktive fluorophore |
Country Status (7)
Country | Link |
---|---|
US (4) | US7563891B2 (de) |
EP (3) | EP2036953A3 (de) |
JP (1) | JP2008500446A (de) |
AT (1) | ATE532830T1 (de) |
AU (1) | AU2005280581B9 (de) |
CA (1) | CA2567387A1 (de) |
WO (1) | WO2006025887A2 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2029799T3 (da) | 2006-04-20 | 2012-12-10 | Becton Dickinson Co | Termostabile proteiner og fremgangsmåder til fremstilling og anvendelse heraf |
DE112006003967B4 (de) * | 2006-07-28 | 2017-09-21 | Pierce Biotechnology, Inc. | Farbstoffe, Farbstoffzusammensetzungen und Verfahren zum Anfärben von Proteinen |
US7553869B2 (en) | 2006-07-28 | 2009-06-30 | Pierce Biotechnology, Inc. | Protein probe compounds, compositions, and methods |
WO2008147805A2 (en) * | 2007-05-22 | 2008-12-04 | Becton, Dickinson And Company | Dyes having ratiometric fluorescence response for detecting metabolites |
WO2008154332A1 (en) * | 2007-06-06 | 2008-12-18 | Becton, Dickinson And Company | Near-infrared dyes as surface enhanced raman scattering reporters |
US8465981B2 (en) * | 2007-08-06 | 2013-06-18 | University Of Kentucky Research Foundation | Polypeptides, systems, and methods useful for detecting glucose |
US9023661B2 (en) * | 2007-10-18 | 2015-05-05 | Becton, Dickinson And Company | Visual glucose sensor and methods of use thereof |
CN101177539B (zh) * | 2007-10-26 | 2010-10-27 | 淮海工学院 | 含香豆素的半菁染料 |
US8389290B2 (en) | 2007-11-30 | 2013-03-05 | Becton, Dickinson And Company | Biosensor device for sensing amphipathic analytes |
JP5585960B2 (ja) * | 2008-02-29 | 2014-09-10 | 独立行政法人理化学研究所 | チオールの検出方法 |
JP2009242379A (ja) * | 2008-03-11 | 2009-10-22 | Osaka Prefecture Univ | 共役化合物、該共役化合物を用いた光電変換素子及び光電気化学電池及び光電変換素子電解液 |
US8741591B2 (en) | 2009-10-09 | 2014-06-03 | The Research Foundation For The State University Of New York | pH-insensitive glucose indicator protein |
US8403332B2 (en) * | 2009-12-28 | 2013-03-26 | Nissan Kogyo Co., Ltd | Seal member |
CN102183471A (zh) * | 2011-01-11 | 2011-09-14 | 山西大学 | 检测硫醇的方法和试剂盒 |
WO2013035513A1 (ja) * | 2011-09-09 | 2013-03-14 | 株式会社島津製作所 | 親水性チオールプローブ |
KR101508564B1 (ko) | 2011-12-09 | 2015-04-07 | 고려대학교 산학협력단 | 스쿠아레인 유도체, 염료감응 태양전지용 염료 및 염료감응 태양전지 |
EP2831583B1 (de) | 2012-03-28 | 2019-12-18 | Becton, Dickinson and Company | Hydrogelhaftung an geformten polymeren |
CN102659775A (zh) * | 2012-04-28 | 2012-09-12 | 苏州大学 | 一种检测硫醇类化合物的荧光探针及其制备方法和用途 |
WO2015029050A1 (en) * | 2013-08-30 | 2015-03-05 | Council Of Scientific & Industrial Research | A squaraine based fluorescent probe and a process for the preparation thereof |
WO2015151071A2 (en) * | 2014-04-04 | 2015-10-08 | Jawaharlal Nehru Centre For Advanced Scientific Research | Small molecular probes, processes and use thereof |
WO2017087051A1 (en) * | 2015-11-20 | 2017-05-26 | Duke University | Glucose biosensors and uses thereof |
CN108727859B (zh) * | 2017-05-23 | 2019-12-17 | 福州大学 | 方酸染料及其在比色荧光双响应铜离子探针制备的应用 |
CN111757918B (zh) * | 2018-02-28 | 2022-04-26 | 富士胶片株式会社 | 树脂组合物、膜、滤光器、图像显示装置、固体摄像元件及化合物 |
CN114524809B (zh) * | 2022-02-14 | 2023-06-13 | 五邑大学 | 一种香豆素衍生物及其制备方法和应用 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5113035B2 (de) * | 1973-04-02 | 1976-04-24 | ||
JPS57146771A (en) * | 1981-03-09 | 1982-09-10 | Mitsubishi Chem Ind Ltd | Coumarin derivative |
JPS5855861A (ja) * | 1981-09-30 | 1983-04-02 | Toshihiko Namihisa | 新規な螢光標識抗体及びその製造方法 |
US4507480A (en) * | 1983-05-09 | 1985-03-26 | Xerox Corporation | Squaraines |
JPS60169453A (ja) | 1984-02-13 | 1985-09-02 | Mitsubishi Chem Ind Ltd | 2,4−ビス(2′−モノ置換アミノ−4′−ジ置換アミノフエニル)シクロブテンジイリウム−1,3−ジオレ−ト類 |
JPS60228448A (ja) | 1984-04-27 | 1985-11-13 | Mitsubishi Chem Ind Ltd | スクアリリウム化合物 |
US5122602A (en) * | 1989-02-13 | 1992-06-16 | Miles Inc. | Chromogenic merocyanine enzyme substrates |
EP0552108B1 (de) * | 1992-01-17 | 1999-11-10 | Lakowicz, Joseph R. | Phasenmodulationsenergieübertragungsfluoroimmunassay |
GB9602265D0 (en) * | 1996-02-05 | 1996-04-03 | Amersham Int Plc | Benzophenoxazine dyes |
US6140494A (en) | 1996-04-19 | 2000-10-31 | Amersham Pharmacia Biotech Uk Limited | Squarate dyes and their use in fluorescent sequencing method |
US5830912A (en) | 1996-11-15 | 1998-11-03 | Molecular Probes, Inc. | Derivatives of 6,8-difluoro-7-hydroxycoumarin |
US5696157A (en) | 1996-11-15 | 1997-12-09 | Molecular Probes, Inc. | Sulfonated derivatives of 7-aminocoumarin |
AU5907998A (en) * | 1997-02-28 | 1998-09-18 | Joseph R Lakowicz | Measuring analytes with metal-ligand complex probes |
JPH10330337A (ja) * | 1997-06-02 | 1998-12-15 | Aisin Seiki Co Ltd | 複環式アミド酸及び複環式マレイミド並びにこれらの製造方法 |
EP1044374B1 (de) * | 1997-12-31 | 2008-10-08 | Duke University | Glukosebiosensor |
US6214628B1 (en) * | 1998-01-14 | 2001-04-10 | Joseph R. Lakowicz | Method of conducting an assay of a sample containing an analyte of interest |
US6538129B1 (en) * | 1999-04-07 | 2003-03-25 | Ewald A. Terpetschnig | Luminescent compounds |
WO2000003727A1 (en) | 1998-07-17 | 2000-01-27 | University Of Maryland, Baltimore | Engineered proteins for analyte sensing |
US6395556B1 (en) * | 1998-11-11 | 2002-05-28 | Joseph R. Lakowicz | Polarization based sensing |
DE69909327T2 (de) * | 1998-12-21 | 2004-04-22 | Sequella, Inc. | Verwendungsmethoden und zusammenstellungen enthaltend überwachungsystem |
CA2366263A1 (en) | 1999-03-31 | 2000-10-05 | Amersham Pharmacia Biotech Uk Limited | Squaraine dyes |
DE19937024A1 (de) | 1999-08-05 | 2001-02-08 | Bayer Ag | Verwendung von Acylsulfonamido substituierten Polymethin-Farbstoffen als Fluoreszenz-Farbstoffe und/oder Marker |
US7566783B2 (en) * | 2000-07-21 | 2009-07-28 | Joseph R Lakowicz | Long wavelength long lifetime luminophores |
US6605459B2 (en) | 2001-07-13 | 2003-08-12 | Paradigm Genetics, Inc. | Methods for measuring cysteine and determining cysteine synthase activity |
US6977180B2 (en) * | 2001-08-28 | 2005-12-20 | Duke University | Biosensor |
DE10160524A1 (de) * | 2001-12-05 | 2003-06-26 | Dyomics Gmbh | Neue Fluoreszenzmarker mit großem Stokes-Shift |
US7851593B2 (en) * | 2002-01-04 | 2010-12-14 | Becton, Dickinson And Company | Binding proteins as biosensors |
US20030153026A1 (en) * | 2002-01-04 | 2003-08-14 | Javier Alarcon | Entrapped binding protein as biosensors |
US6855556B2 (en) * | 2002-01-04 | 2005-02-15 | Becton, Dickinson And Company | Binding protein as biosensors |
JP2005524084A (ja) * | 2002-04-30 | 2005-08-11 | ユニバーシティ オブ メリーランド,ボルチモア | 蛍光検出法 |
US20040087842A1 (en) * | 2002-05-30 | 2004-05-06 | Lakowicz Joseph R. | Fluorescent probes for saccharrides |
DK1552303T3 (da) * | 2002-10-16 | 2009-05-25 | Univ Duke | Biosensor til påvisning af glukose |
US20040234962A1 (en) * | 2003-05-02 | 2004-11-25 | Javier Alarcon | Multicoated or multilayer entrapment matrix for protein biosensor |
US7718353B2 (en) | 2003-05-09 | 2010-05-18 | University Of Maryland Baltimore County | Proteins, sensors, and methods of characterizing analytes using the same |
US7304168B2 (en) | 2003-08-14 | 2007-12-04 | Board Of Regents, University Of Texas System | Photo-caged fluorescent molecules |
-
2005
- 2005-05-18 US US11/131,283 patent/US7563891B2/en not_active Expired - Fee Related
- 2005-05-20 EP EP08017855A patent/EP2036953A3/de not_active Withdrawn
- 2005-05-20 CA CA002567387A patent/CA2567387A1/en not_active Abandoned
- 2005-05-20 WO PCT/US2005/017648 patent/WO2006025887A2/en active Application Filing
- 2005-05-20 AT AT10163379T patent/ATE532830T1/de active
- 2005-05-20 AU AU2005280581A patent/AU2005280581B9/en not_active Ceased
- 2005-05-20 JP JP2007527456A patent/JP2008500446A/ja active Pending
- 2005-05-20 EP EP05812138A patent/EP1751236A2/de not_active Withdrawn
- 2005-05-20 EP EP10163379A patent/EP2223971B1/de not_active Not-in-force
-
2009
- 2009-06-22 US US12/489,121 patent/US8129525B2/en not_active Expired - Fee Related
- 2009-06-22 US US12/489,145 patent/US8071794B2/en not_active Expired - Fee Related
- 2009-06-22 US US12/489,078 patent/US7767821B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20100167417A1 (en) | 2010-07-01 |
EP2223971A1 (de) | 2010-09-01 |
WO2006025887A3 (en) | 2006-08-10 |
US8071794B2 (en) | 2011-12-06 |
US20110184168A1 (en) | 2011-07-28 |
AU2005280581B2 (en) | 2011-09-08 |
CA2567387A1 (en) | 2006-03-09 |
EP2036953A2 (de) | 2009-03-18 |
EP1751236A2 (de) | 2007-02-14 |
WO2006025887A2 (en) | 2006-03-09 |
US7767821B2 (en) | 2010-08-03 |
EP2223971B1 (de) | 2011-11-09 |
EP2036953A3 (de) | 2010-07-14 |
US7563891B2 (en) | 2009-07-21 |
JP2008500446A (ja) | 2008-01-10 |
AU2005280581B9 (en) | 2012-02-02 |
AU2005280581A1 (en) | 2006-03-09 |
US20060280652A1 (en) | 2006-12-14 |
US20100003763A1 (en) | 2010-01-07 |
US8129525B2 (en) | 2012-03-06 |
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