ATE532830T1 - Langwellige thiolgruppenreaktive fluorophore - Google Patents

Langwellige thiolgruppenreaktive fluorophore

Info

Publication number
ATE532830T1
ATE532830T1 AT10163379T AT10163379T ATE532830T1 AT E532830 T1 ATE532830 T1 AT E532830T1 AT 10163379 T AT10163379 T AT 10163379T AT 10163379 T AT10163379 T AT 10163379T AT E532830 T1 ATE532830 T1 AT E532830T1
Authority
AT
Austria
Prior art keywords
thiol group
long wave
group reactive
reactive fluorophores
fluorophores
Prior art date
Application number
AT10163379T
Other languages
English (en)
Inventor
Bruce Pitner
Douglas Sherman
Arounaguiry Ambroise
Joseph Thomas
Original Assignee
Becton Dickinson Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co
Application granted granted Critical
Publication of ATE532830T1 publication Critical patent/ATE532830T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/10The polymethine chain containing an even number of >CH- groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/10The polymethine chain containing an even number of >CH- groups
    • C09B23/105The polymethine chain containing an even number of >CH- groups two >CH- groups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT10163379T 2004-05-21 2005-05-20 Langwellige thiolgruppenreaktive fluorophore ATE532830T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57394404P 2004-05-21 2004-05-21
US59951404P 2004-08-06 2004-08-06

Publications (1)

Publication Number Publication Date
ATE532830T1 true ATE532830T1 (de) 2011-11-15

Family

ID=35788237

Family Applications (1)

Application Number Title Priority Date Filing Date
AT10163379T ATE532830T1 (de) 2004-05-21 2005-05-20 Langwellige thiolgruppenreaktive fluorophore

Country Status (7)

Country Link
US (4) US7563891B2 (de)
EP (3) EP2036953A3 (de)
JP (1) JP2008500446A (de)
AT (1) ATE532830T1 (de)
AU (1) AU2005280581B9 (de)
CA (1) CA2567387A1 (de)
WO (1) WO2006025887A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2029799T3 (da) 2006-04-20 2012-12-10 Becton Dickinson Co Termostabile proteiner og fremgangsmåder til fremstilling og anvendelse heraf
DE112006003967B4 (de) * 2006-07-28 2017-09-21 Pierce Biotechnology, Inc. Farbstoffe, Farbstoffzusammensetzungen und Verfahren zum Anfärben von Proteinen
US7553869B2 (en) 2006-07-28 2009-06-30 Pierce Biotechnology, Inc. Protein probe compounds, compositions, and methods
WO2008147805A2 (en) * 2007-05-22 2008-12-04 Becton, Dickinson And Company Dyes having ratiometric fluorescence response for detecting metabolites
WO2008154332A1 (en) * 2007-06-06 2008-12-18 Becton, Dickinson And Company Near-infrared dyes as surface enhanced raman scattering reporters
US8465981B2 (en) * 2007-08-06 2013-06-18 University Of Kentucky Research Foundation Polypeptides, systems, and methods useful for detecting glucose
US9023661B2 (en) * 2007-10-18 2015-05-05 Becton, Dickinson And Company Visual glucose sensor and methods of use thereof
CN101177539B (zh) * 2007-10-26 2010-10-27 淮海工学院 含香豆素的半菁染料
US8389290B2 (en) 2007-11-30 2013-03-05 Becton, Dickinson And Company Biosensor device for sensing amphipathic analytes
JP5585960B2 (ja) * 2008-02-29 2014-09-10 独立行政法人理化学研究所 チオールの検出方法
JP2009242379A (ja) * 2008-03-11 2009-10-22 Osaka Prefecture Univ 共役化合物、該共役化合物を用いた光電変換素子及び光電気化学電池及び光電変換素子電解液
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
US8403332B2 (en) * 2009-12-28 2013-03-26 Nissan Kogyo Co., Ltd Seal member
CN102183471A (zh) * 2011-01-11 2011-09-14 山西大学 检测硫醇的方法和试剂盒
WO2013035513A1 (ja) * 2011-09-09 2013-03-14 株式会社島津製作所 親水性チオールプローブ
KR101508564B1 (ko) 2011-12-09 2015-04-07 고려대학교 산학협력단 스쿠아레인 유도체, 염료감응 태양전지용 염료 및 염료감응 태양전지
EP2831583B1 (de) 2012-03-28 2019-12-18 Becton, Dickinson and Company Hydrogelhaftung an geformten polymeren
CN102659775A (zh) * 2012-04-28 2012-09-12 苏州大学 一种检测硫醇类化合物的荧光探针及其制备方法和用途
WO2015029050A1 (en) * 2013-08-30 2015-03-05 Council Of Scientific & Industrial Research A squaraine based fluorescent probe and a process for the preparation thereof
WO2015151071A2 (en) * 2014-04-04 2015-10-08 Jawaharlal Nehru Centre For Advanced Scientific Research Small molecular probes, processes and use thereof
WO2017087051A1 (en) * 2015-11-20 2017-05-26 Duke University Glucose biosensors and uses thereof
CN108727859B (zh) * 2017-05-23 2019-12-17 福州大学 方酸染料及其在比色荧光双响应铜离子探针制备的应用
CN111757918B (zh) * 2018-02-28 2022-04-26 富士胶片株式会社 树脂组合物、膜、滤光器、图像显示装置、固体摄像元件及化合物
CN114524809B (zh) * 2022-02-14 2023-06-13 五邑大学 一种香豆素衍生物及其制备方法和应用

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113035B2 (de) * 1973-04-02 1976-04-24
JPS57146771A (en) * 1981-03-09 1982-09-10 Mitsubishi Chem Ind Ltd Coumarin derivative
JPS5855861A (ja) * 1981-09-30 1983-04-02 Toshihiko Namihisa 新規な螢光標識抗体及びその製造方法
US4507480A (en) * 1983-05-09 1985-03-26 Xerox Corporation Squaraines
JPS60169453A (ja) 1984-02-13 1985-09-02 Mitsubishi Chem Ind Ltd 2,4−ビス(2′−モノ置換アミノ−4′−ジ置換アミノフエニル)シクロブテンジイリウム−1,3−ジオレ−ト類
JPS60228448A (ja) 1984-04-27 1985-11-13 Mitsubishi Chem Ind Ltd スクアリリウム化合物
US5122602A (en) * 1989-02-13 1992-06-16 Miles Inc. Chromogenic merocyanine enzyme substrates
EP0552108B1 (de) * 1992-01-17 1999-11-10 Lakowicz, Joseph R. Phasenmodulationsenergieübertragungsfluoroimmunassay
GB9602265D0 (en) * 1996-02-05 1996-04-03 Amersham Int Plc Benzophenoxazine dyes
US6140494A (en) 1996-04-19 2000-10-31 Amersham Pharmacia Biotech Uk Limited Squarate dyes and their use in fluorescent sequencing method
US5830912A (en) 1996-11-15 1998-11-03 Molecular Probes, Inc. Derivatives of 6,8-difluoro-7-hydroxycoumarin
US5696157A (en) 1996-11-15 1997-12-09 Molecular Probes, Inc. Sulfonated derivatives of 7-aminocoumarin
AU5907998A (en) * 1997-02-28 1998-09-18 Joseph R Lakowicz Measuring analytes with metal-ligand complex probes
JPH10330337A (ja) * 1997-06-02 1998-12-15 Aisin Seiki Co Ltd 複環式アミド酸及び複環式マレイミド並びにこれらの製造方法
EP1044374B1 (de) * 1997-12-31 2008-10-08 Duke University Glukosebiosensor
US6214628B1 (en) * 1998-01-14 2001-04-10 Joseph R. Lakowicz Method of conducting an assay of a sample containing an analyte of interest
US6538129B1 (en) * 1999-04-07 2003-03-25 Ewald A. Terpetschnig Luminescent compounds
WO2000003727A1 (en) 1998-07-17 2000-01-27 University Of Maryland, Baltimore Engineered proteins for analyte sensing
US6395556B1 (en) * 1998-11-11 2002-05-28 Joseph R. Lakowicz Polarization based sensing
DE69909327T2 (de) * 1998-12-21 2004-04-22 Sequella, Inc. Verwendungsmethoden und zusammenstellungen enthaltend überwachungsystem
CA2366263A1 (en) 1999-03-31 2000-10-05 Amersham Pharmacia Biotech Uk Limited Squaraine dyes
DE19937024A1 (de) 1999-08-05 2001-02-08 Bayer Ag Verwendung von Acylsulfonamido substituierten Polymethin-Farbstoffen als Fluoreszenz-Farbstoffe und/oder Marker
US7566783B2 (en) * 2000-07-21 2009-07-28 Joseph R Lakowicz Long wavelength long lifetime luminophores
US6605459B2 (en) 2001-07-13 2003-08-12 Paradigm Genetics, Inc. Methods for measuring cysteine and determining cysteine synthase activity
US6977180B2 (en) * 2001-08-28 2005-12-20 Duke University Biosensor
DE10160524A1 (de) * 2001-12-05 2003-06-26 Dyomics Gmbh Neue Fluoreszenzmarker mit großem Stokes-Shift
US7851593B2 (en) * 2002-01-04 2010-12-14 Becton, Dickinson And Company Binding proteins as biosensors
US20030153026A1 (en) * 2002-01-04 2003-08-14 Javier Alarcon Entrapped binding protein as biosensors
US6855556B2 (en) * 2002-01-04 2005-02-15 Becton, Dickinson And Company Binding protein as biosensors
JP2005524084A (ja) * 2002-04-30 2005-08-11 ユニバーシティ オブ メリーランド,ボルチモア 蛍光検出法
US20040087842A1 (en) * 2002-05-30 2004-05-06 Lakowicz Joseph R. Fluorescent probes for saccharrides
DK1552303T3 (da) * 2002-10-16 2009-05-25 Univ Duke Biosensor til påvisning af glukose
US20040234962A1 (en) * 2003-05-02 2004-11-25 Javier Alarcon Multicoated or multilayer entrapment matrix for protein biosensor
US7718353B2 (en) 2003-05-09 2010-05-18 University Of Maryland Baltimore County Proteins, sensors, and methods of characterizing analytes using the same
US7304168B2 (en) 2003-08-14 2007-12-04 Board Of Regents, University Of Texas System Photo-caged fluorescent molecules

Also Published As

Publication number Publication date
US20100167417A1 (en) 2010-07-01
EP2223971A1 (de) 2010-09-01
WO2006025887A3 (en) 2006-08-10
US8071794B2 (en) 2011-12-06
US20110184168A1 (en) 2011-07-28
AU2005280581B2 (en) 2011-09-08
CA2567387A1 (en) 2006-03-09
EP2036953A2 (de) 2009-03-18
EP1751236A2 (de) 2007-02-14
WO2006025887A2 (en) 2006-03-09
US7767821B2 (en) 2010-08-03
EP2223971B1 (de) 2011-11-09
EP2036953A3 (de) 2010-07-14
US7563891B2 (en) 2009-07-21
JP2008500446A (ja) 2008-01-10
AU2005280581B9 (en) 2012-02-02
AU2005280581A1 (en) 2006-03-09
US20060280652A1 (en) 2006-12-14
US20100003763A1 (en) 2010-01-07
US8129525B2 (en) 2012-03-06

Similar Documents

Publication Publication Date Title
ATE532830T1 (de) Langwellige thiolgruppenreaktive fluorophore
ATE514755T1 (de) Fluoreszenzfarbstoffe zur verwendung bei der glukoseerfassung
DE602006016589D1 (de) Neue markierungsstrategien für den empfindlichen nachweis von analyten
WO2009058902A3 (en) Methods and devices for analyte detection
WO2007120265A3 (en) Coded molecules for detecting target analytes
DK1869459T3 (da) Lipofil farve-baserede assays for clostridial-toksin-aktivitet
DE602005026683D1 (de) Faseroptik zum abtasten von analyten und herstellungsverfahren dafür
WO2005073732A3 (en) Lc/ms method of analyzing high molecular weight proteins
ATE480642T1 (de) Verfahren zur bestimmung von genotoxizität
DE602004001227D1 (de) Nukleinsäure-biosensor
NO20071927L (no) Peptidsyklisering.
DK2118666T3 (da) Fremgangsmåde til normalisering af koncentrationen af analytter i en urinprøve
ATE511636T1 (de) Verfahren zum nachweis biologischer organismen mittels raman-streuung
HK1073887A1 (en) A sensor for electro-chemical analysis of a sample and the method for maunfacturing the same
DK2016421T3 (da) Reagenser og fremgangsmåder til detektering af proteiner ved hjælp af farvestoffer og dextriner
DE60143888D1 (de) Methode um die sensitivität einer luminesenz assay zu erhöhen
MY173855A (en) Amperometric biosensor for histamine determination
ATE551598T1 (de) Fluorimetrische bestimmung von analyten durch ein intramolekulares quencher-fluorophor-konjugat
DE60301821D1 (de) Küvette für ein Lesegerät zur Bestimmung von Substanzen mittels der Evaneszenzfeldmethode
DE502005002108D1 (de) Verfahren zur funktionalisierung von biosensor-chips
WO2005094441A3 (en) Split enzyme linked immunosorbent and nucleic acid assays
FR2853077B1 (fr) Procedes immunochromatographiques en phase solide
ATE306082T1 (de) Nachweis der bindung von ladungsträgern mittels ph- oder potential-sensitiver sonden
DE602005014025D1 (de) Nachweisreagenz für Noroviridae
DE602004016906D1 (de) Reagenz zum Nachweis von anti-Phospholipid Antikörper