DE60326256D1 - Biosensor zum nachweis von glukose - Google Patents

Biosensor zum nachweis von glukose

Info

Publication number
DE60326256D1
DE60326256D1 DE60326256T DE60326256T DE60326256D1 DE 60326256 D1 DE60326256 D1 DE 60326256D1 DE 60326256 T DE60326256 T DE 60326256T DE 60326256 T DE60326256 T DE 60326256T DE 60326256 D1 DE60326256 D1 DE 60326256D1
Authority
DE
Germany
Prior art keywords
biosensor
glucose
detection
covalently
reporter group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60326256T
Other languages
English (en)
Inventor
Homme W Hellinga
Loren L Looger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Application granted granted Critical
Publication of DE60326256D1 publication Critical patent/DE60326256D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
DE60326256T 2002-10-16 2003-10-16 Biosensor zum nachweis von glukose Expired - Lifetime DE60326256D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41835902P 2002-10-16 2002-10-16
PCT/US2003/032581 WO2004036176A2 (en) 2002-10-16 2003-10-16 Biosensor

Publications (1)

Publication Number Publication Date
DE60326256D1 true DE60326256D1 (de) 2009-04-02

Family

ID=32107920

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60326256T Expired - Lifetime DE60326256D1 (de) 2002-10-16 2003-10-16 Biosensor zum nachweis von glukose

Country Status (13)

Country Link
US (3) US9625458B2 (de)
EP (1) EP1552303B1 (de)
JP (1) JP4571499B2 (de)
KR (1) KR101107630B1 (de)
CN (1) CN100492010C (de)
AT (1) ATE423318T1 (de)
AU (1) AU2003277377B2 (de)
CA (1) CA2502272C (de)
DE (1) DE60326256D1 (de)
DK (1) DK1552303T3 (de)
ES (1) ES2321931T3 (de)
HK (1) HK1080937A1 (de)
WO (1) WO2004036176A2 (de)

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US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
ES2657627T3 (es) * 2003-06-20 2018-03-06 F. Hoffmann-La Roche Ag Biosensores electroquímicos
CA2529378C (en) 2003-06-20 2014-04-15 F.Hoffmann-La Roche Ag Method and reagent for producing narrow, homogenous reagent strips
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
US20050112685A1 (en) * 2003-11-26 2005-05-26 Amiss Terry J. Compositions and methods for measuring analyte concentrations
US20050181116A1 (en) * 2004-02-18 2005-08-18 Rob Worsham Method for coating a medical device using a matrix assisted pulsed-laser evaporation technique and associated system and medical device
US20050181141A1 (en) * 2004-02-18 2005-08-18 Aiden Flanagan Laser-induced explosive vaporization coating method, associated system, and device made by the method
US20050188921A1 (en) * 2004-02-27 2005-09-01 Anthony Malone Matrix assisted pulsed-laser evaporation technique for coating a medical device and associated system and medical device
US7563891B2 (en) * 2004-05-21 2009-07-21 Becton, Dickinson & Company Long wavelength thiol-reactive fluorophores
AU2005295656B2 (en) * 2004-10-14 2011-08-04 Carnegie Institution Of Washington Development of sensitive FRET sensors and methods of using the same
ATE540048T1 (de) * 2004-10-14 2012-01-15 Carnegie Inst Of Washington Neurotransmittersensoren und verfahren zu ihrer verwendung
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
WO2006096213A1 (en) * 2005-03-03 2006-09-14 Carnegie Institution Of Washington Polyamine sensors and methods of using the same
WO2006096214A1 (en) * 2005-03-04 2006-09-14 Carnegie Institution Of Washington Environmentally stable sensors and methods of using the same
US20070154947A1 (en) * 2005-08-31 2007-07-05 The Trustees Of Princeton University Chemical biodiscriminator
JP5148497B2 (ja) * 2005-10-14 2013-02-20 カーネギー インスチチューション オブ ワシントン スクロースバイオセンサーおよびそれを用いる方法
AU2005337168B2 (en) * 2005-10-14 2012-07-05 Carnegie Institution Of Washington Phosphate biosensors and methods of using the same
US20080311047A1 (en) * 2005-11-16 2008-12-18 Thijs Kaper Multimetric Biosensors and Methods of Using Same
JP5513370B2 (ja) 2007-04-20 2014-06-04 ベクトン・ディキンソン・アンド・カンパニー ヒドロゲル組成物
EP2150586B1 (de) * 2007-05-22 2018-03-14 Becton, Dickinson and Company Farbstoffe mti ratiometrischer fluoreszenzreaktion für den nachweis von metaboliten
US8129532B2 (en) * 2007-08-03 2012-03-06 The University Of Connecticut Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use
WO2009021052A1 (en) * 2007-08-06 2009-02-12 University Of Kentucky Research Foundation Polypeptides, systems, and methods useful for detecting glucose
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
US10684282B2 (en) 2011-10-07 2020-06-16 Howard Hughes Medical Institute Genetically encoded biosensors
US9719992B2 (en) 2011-10-07 2017-08-01 Howard Hughes Medical Institute Genetically encoded biosensors
US10466247B2 (en) 2012-11-20 2019-11-05 Becton, Dickinson And Company System and method for diagnosing sensor performance using analyte-independent ratiometric signals
US20140212987A1 (en) * 2013-01-30 2014-07-31 Siemens Healthcare Diagnostics Inc. Signal Ratio in Assay Calibrators
KR101455244B1 (ko) 2013-02-04 2014-10-31 경희대학교 산학협력단 Afm과 탐침형 센서를 이용한 세포독성의 정량적 평가시스템 및 방법
EP3036249B1 (de) 2013-08-23 2019-03-13 Boehringer Ingelheim RCV GmbH & Co KG Neue adsorbenszusammensetzung und ihre anwendung
US10379125B2 (en) 2013-12-27 2019-08-13 Becton, Dickinson And Company System and method for dynamically calibrating and measuring analyte concentration in diabetes management monitors
EP3362468A1 (de) 2015-10-13 2018-08-22 The Research Foundation for the State University of New York Spaltbares fusionsetikett zur überexpression und reinigung von proteinen
WO2017087917A2 (en) 2015-11-20 2017-05-26 Duke University Bicarbonate biosensors, calcium biosensors, and uses thereof
CN108474021A (zh) * 2015-11-20 2018-08-31 杜克大学 葡萄糖生物传感器及其用途
EP3377904B1 (de) 2015-11-20 2024-05-01 Duke University Harnstoffbiosensoren und verwendungen davon
US11099176B2 (en) 2015-11-20 2021-08-24 Duke University Lactate biosensors and uses thereof
CA3005890A1 (en) 2015-11-20 2017-05-26 Duke University Thermostable glucose biosensors and uses thereof
GB201714478D0 (en) * 2017-09-08 2017-10-25 Univ Bristol Sensor
EP4007767A4 (de) * 2019-08-01 2023-08-02 The Trustees of Indiana University Glyphosat-biosensor
CN113980992B (zh) * 2021-12-29 2022-03-25 中国科学院天津工业生物技术研究所 一种l-半胱氨酸生物传感器及其应用

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SE9301270D0 (sv) * 1993-04-19 1993-04-17 Biosensor
US6171520B1 (en) 1996-03-15 2001-01-09 Ss Pharmaceutical Co., Ltd. Reagents for labeling SH groups, process for the preparation of them and method for labeling with them
US6130037A (en) * 1996-04-25 2000-10-10 Pence And Mcgill University Biosensor device and method
SE9602545L (sv) 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
WO1998053849A1 (en) 1997-05-27 1998-12-03 Yale University Synthetic metalloproteins and method of preparation thereof
AUPO714897A0 (en) 1997-06-03 1997-06-26 Australian Membrane And Biotechnology Research Institute Model membrane systems
US6013459A (en) * 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
ES2314996T3 (es) * 1997-12-31 2009-03-16 Duke University Biosensor de glucosa.
CA2327400A1 (en) 1998-04-06 1999-10-14 Bunsen Rush Laboratories, Inc. Directed evolution biosensors
IL124903A0 (en) * 1998-06-15 1999-01-26 Bauer Alan Josef An enzyme biosensor
CA2336985C (en) * 1998-07-17 2011-01-04 University Of Maryland, Baltimore Method of glucose or galactose detection with glucose/galactose binding protein
US6663862B1 (en) * 1999-06-04 2003-12-16 Duke University Reagents for detection and purification of antibody fragments
GB9923146D0 (en) * 1999-09-30 1999-12-01 Imperial College Detector array
JP4358626B2 (ja) 2001-08-28 2009-11-04 デューク ユニバーシティ バイオセンサー
US6855556B2 (en) * 2002-01-04 2005-02-15 Becton, Dickinson And Company Binding protein as biosensors
JP4571499B2 (ja) 2002-10-16 2010-10-27 デューク ユニバーシティ バイオセンサ
WO2005007806A2 (en) 2003-05-07 2005-01-27 Duke University Protein design for receptor-ligand recognition and binding
EP2150586B1 (de) * 2007-05-22 2018-03-14 Becton, Dickinson and Company Farbstoffe mti ratiometrischer fluoreszenzreaktion für den nachweis von metaboliten
WO2008154332A1 (en) * 2007-06-06 2008-12-18 Becton, Dickinson And Company Near-infrared dyes as surface enhanced raman scattering reporters
US9023661B2 (en) * 2007-10-18 2015-05-05 Becton, Dickinson And Company Visual glucose sensor and methods of use thereof

Also Published As

Publication number Publication date
EP1552303B1 (de) 2009-02-18
US20170322209A1 (en) 2017-11-09
US20040118681A1 (en) 2004-06-24
KR101107630B1 (ko) 2012-01-25
EP1552303A2 (de) 2005-07-13
US10712341B2 (en) 2020-07-14
WO2004036176A3 (en) 2004-07-29
US20080166747A1 (en) 2008-07-10
CN1705882A (zh) 2005-12-07
KR20050083772A (ko) 2005-08-26
JP4571499B2 (ja) 2010-10-27
ATE423318T1 (de) 2009-03-15
US9625458B2 (en) 2017-04-18
CA2502272A1 (en) 2004-04-29
HK1080937A1 (en) 2006-05-04
EP1552303A4 (de) 2006-12-27
AU2003277377B2 (en) 2009-05-21
DK1552303T3 (da) 2009-05-25
CA2502272C (en) 2011-10-11
CN100492010C (zh) 2009-05-27
JP2006503293A (ja) 2006-01-26
AU2003277377A1 (en) 2004-05-04
WO2004036176A2 (en) 2004-04-29
ES2321931T3 (es) 2009-06-15

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Legal Events

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