AU2001283901A1 - Competitive assay method - Google Patents

Competitive assay method

Info

Publication number
AU2001283901A1
AU2001283901A1 AU2001283901A AU8390101A AU2001283901A1 AU 2001283901 A1 AU2001283901 A1 AU 2001283901A1 AU 2001283901 A AU2001283901 A AU 2001283901A AU 8390101 A AU8390101 A AU 8390101A AU 2001283901 A1 AU2001283901 A1 AU 2001283901A1
Authority
AU
Australia
Prior art keywords
molecules
property
detected
solution
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001283901A
Inventor
Franz-Josef Meyer-Almes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PerkinElmer Cellular Technologies Germany GmbH
Original Assignee
EVOTEC ANALYTICAL SYS GmbH
Evotec Analytical Systems GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EVOTEC ANALYTICAL SYS GmbH, Evotec Analytical Systems GmbH filed Critical EVOTEC ANALYTICAL SYS GmbH
Publication of AU2001283901A1 publication Critical patent/AU2001283901A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

Abstract

The invention relates to a competitive assay method, for determining the binding of molecules, with the following method steps: a) production of a solution with at least two molecular associations (A, B) interacting with each other, each comprising at least two different molecules (A, A´; B, B´), whereby the binding of at least two molecules in the solution is affected by a change in the property to be detected, b) determination of the at least one property to be detected. The invention further relates to a test method for the determination of the effect of synthetic or biological substances on the binding properties of molecules in molecular associations, comprising the following steps: - production of a solution with at least two molecular associations (A, B) interacting with each other, each comprising at least two different molecules (A, A´; B, B´), whereby the binding of at least two molecules in the solution is affected by a change in the property to be detected, addition of an analyte and determination of the at least one property to be detected.
AU2001283901A 2000-06-29 2001-06-29 Competitive assay method Abandoned AU2001283901A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10030798 2000-06-29
DE10030798A DE10030798A1 (en) 2000-06-29 2000-06-29 Competitive assay procedure
PCT/EP2001/007424 WO2002001226A1 (en) 2000-06-29 2001-06-29 Competitive assay method

Publications (1)

Publication Number Publication Date
AU2001283901A1 true AU2001283901A1 (en) 2002-01-08

Family

ID=7646661

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001283901A Abandoned AU2001283901A1 (en) 2000-06-29 2001-06-29 Competitive assay method

Country Status (5)

Country Link
EP (1) EP1295124B1 (en)
AT (1) ATE259964T1 (en)
AU (1) AU2001283901A1 (en)
DE (2) DE10030798A1 (en)
WO (1) WO2002001226A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040067502A1 (en) * 2000-10-11 2004-04-08 Rolf Guenther Multiplex assays using nanoparticles
JP2007508810A (en) 2003-09-30 2007-04-12 エヴォテック ニューロサイエンシス ゲゼルシャフト ミット ベシュレンクテル ハフツング Diagnostic and therapeutic use of sulfotransferases for neurodegenerative diseases
WO2006015976A1 (en) 2004-08-11 2006-02-16 Evotec Neurosciences Gmbh Diagnostic and therapeutic use of a plasma membrane atpase
WO2006125830A2 (en) 2005-05-27 2006-11-30 Evotec Neurosciences Gmbh Kcnn3 as diagnostic and therapeutic target for neurodegenerative diseases
EP1885886B1 (en) 2005-05-30 2011-11-23 Takeda Pharmaceutical Company Limited Diagnostic and therapeutic target prkx proteins for alzheimer's disease
EP1891234B1 (en) 2005-06-01 2014-12-10 Evotec International GmbH Use of slc39a12 proteins as target in diagnosis and drug screening in alzheimer's disease
EP1891241B1 (en) 2005-06-16 2011-01-12 EVOTEC Neurosciences GmbH Diagnostic and therapeutic target adarb2 proteins for neurodegenerative diseases
DE102006009516B4 (en) * 2006-02-28 2007-12-06 Analyticon Biotechnologies Ag Test device, manufacturing method therefor and test method
EP2053397A1 (en) 2007-10-25 2009-04-29 EVOTEC Neurosciences GmbH PPM1E proteins and nucleic acids as targets for neurodegenerative diseases
TWI614502B (en) * 2017-07-26 2018-02-11 國立成功大學 Detection method for detecting analyte concentration
CN110749737A (en) * 2019-09-26 2020-02-04 南京市产品质量监督检验院 Quantum dot immunochromatography test paper for quantitatively detecting estradiol in milk

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2084317B (en) * 1980-09-30 1984-01-18 Erba Farmitalia Antigen-linked competitive enzymeimmunoassay
EP0105714B1 (en) * 1982-09-29 1988-07-27 Serono Diagnostics Limited Immunoassay of antigens
US5512659A (en) * 1989-08-04 1996-04-30 Syntex (U.S.A.) Inc. Compositions useful in heterogeneous immunoassays
EP0623214A1 (en) * 1992-01-17 1994-11-09 Selective Antibodies Limited Determination of haptens
US5518887A (en) * 1992-03-30 1996-05-21 Abbott Laboratories Immunoassays empolying generic anti-hapten antibodies and materials for use therein
DE19504198A1 (en) * 1995-02-09 1996-08-14 Behringwerke Ag Competitive immunoassay using complex analyte derivatives

Also Published As

Publication number Publication date
EP1295124B1 (en) 2004-02-18
EP1295124A1 (en) 2003-03-26
ATE259964T1 (en) 2004-03-15
DE10030798A1 (en) 2002-01-10
DE50101520D1 (en) 2004-03-25
WO2002001226A1 (en) 2002-01-03

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