CN1004351B - 带有次苯基的斯柏格埃林有关化合物的制备方法 - Google Patents
带有次苯基的斯柏格埃林有关化合物的制备方法 Download PDFInfo
- Publication number
- CN1004351B CN1004351B CN85101425.9A CN85101425A CN1004351B CN 1004351 B CN1004351 B CN 1004351B CN 85101425 A CN85101425 A CN 85101425A CN 1004351 B CN1004351 B CN 1004351B
- Authority
- CN
- China
- Prior art keywords
- azepine decane
- group
- phenyl
- gram
- guanidine radicals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN85101425.9A CN1004351B (zh) | 1984-03-02 | 1985-04-01 | 带有次苯基的斯柏格埃林有关化合物的制备方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59038615A JPS60185758A (ja) | 1984-03-02 | 1984-03-02 | フエニレン基を有するスパガリン関連化合物およびその製造法 |
| CN85101425.9A CN1004351B (zh) | 1984-03-02 | 1985-04-01 | 带有次苯基的斯柏格埃林有关化合物的制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN85101425A CN85101425A (zh) | 1987-01-17 |
| CN1004351B true CN1004351B (zh) | 1989-05-31 |
Family
ID=12530153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN85101425.9A Expired CN1004351B (zh) | 1984-03-02 | 1985-04-01 | 带有次苯基的斯柏格埃林有关化合物的制备方法 |
Country Status (17)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61129119A (ja) * | 1984-11-13 | 1986-06-17 | Microbial Chem Res Found | 新規免疫抑制剤 |
| JPS61165322A (ja) * | 1985-01-14 | 1986-07-26 | Microbial Chem Res Found | スパガリン類の注射用凍結乾燥製剤 |
| JPH075538B2 (ja) * | 1985-08-27 | 1995-01-25 | 財団法人微生物化学研究会 | フエニレン基を有するスパガリン関連ニトリル化合物及びその製造法 |
| JPH0742268B2 (ja) * | 1985-08-27 | 1995-05-10 | 財団法人微生物化学研究会 | フエニレン基を有するスパガリン類縁化合物及びその製造法 |
| ES2039213T3 (es) * | 1986-04-04 | 1993-09-16 | Microbial Chemistry Research Foundation | Procedimiento para producir nuevos compuestos relacionados con espergualina. |
| JP2605762B2 (ja) * | 1986-12-10 | 1997-04-30 | 武田薬品工業株式会社 | δ−ハイドロキシ−β−リジン誘導体およびその製造法 |
| JPH0794424B2 (ja) * | 1987-09-30 | 1995-10-11 | 財団法人微生物化学研究会 | 新スパガリン関連化合物およびその製造法 |
| US5061787A (en) * | 1988-06-24 | 1991-10-29 | Nippon Kayaku Kabushiki Kaisha | Novel spergualin-related compounds and compositions |
| JPH0776204B2 (ja) * | 1988-07-01 | 1995-08-16 | 寳酒造株式会社 | スパガリン類の精製法 |
| US4990536A (en) * | 1989-04-03 | 1991-02-05 | Nippon Kayaku Kabushiki Kaisha | Immunopotentiator and spergualin-related compound therefor |
| US5162581A (en) * | 1989-05-29 | 1992-11-10 | Takaru Shuzo Co., Ltd. | Crystalline deoxyspergualin, process for its preparation and suppository containing the same |
| EP0467280B1 (en) * | 1990-07-20 | 1994-09-28 | Nippon Kayaku Kabushiki Kaisha | Novel spergualin-related compound and use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5748957A (en) * | 1980-09-08 | 1982-03-20 | Microbial Chem Res Found | Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient |
| JPS57185254A (en) * | 1981-05-11 | 1982-11-15 | Microbial Chem Res Found | Novel carcinostatic substances and their preparation |
| JPS5862152A (ja) * | 1981-10-08 | 1983-04-13 | Microbial Chem Res Found | Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法 |
-
1984
- 1984-03-02 JP JP59038615A patent/JPS60185758A/ja active Granted
-
1985
- 1985-02-25 AT AT85102039T patent/ATE38512T1/de not_active IP Right Cessation
- 1985-02-25 EP EP85102039A patent/EP0153720B1/en not_active Expired
- 1985-02-25 DE DE8585102039T patent/DE3566114D1/de not_active Expired
- 1985-02-25 HU HU85692A patent/HU193085B/hu not_active IP Right Cessation
- 1985-02-27 KR KR1019850001233A patent/KR910004378B1/ko not_active IP Right Cessation
- 1985-02-27 US US06/706,312 patent/US4556735A/en not_active Expired - Fee Related
- 1985-02-28 ES ES540784A patent/ES8701720A1/es not_active Expired
- 1985-02-28 CA CA000475473A patent/CA1242452A/en not_active Expired
- 1985-03-01 IE IE518/85A patent/IE57975B1/en not_active IP Right Cessation
- 1985-03-01 AR AR299645A patent/AR241109A1/es active
- 1985-03-01 ZA ZA851567A patent/ZA851567B/xx unknown
- 1985-03-01 DK DK097485A patent/DK164855C/da not_active IP Right Cessation
- 1985-03-01 PT PT80038A patent/PT80038B/pt not_active IP Right Cessation
- 1985-03-01 AU AU39296/85A patent/AU575912B2/en not_active Ceased
- 1985-03-01 GR GR850531A patent/GR850531B/el unknown
- 1985-04-01 CN CN85101425.9A patent/CN1004351B/zh not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU3929685A (en) | 1985-09-05 |
| DK97485D0 (da) | 1985-03-01 |
| PT80038B (pt) | 1987-09-18 |
| AU575912B2 (en) | 1988-08-11 |
| DK164855B (da) | 1992-08-31 |
| HU193085B (en) | 1987-08-28 |
| US4556735A (en) | 1985-12-03 |
| EP0153720B1 (en) | 1988-11-09 |
| EP0153720A2 (en) | 1985-09-04 |
| KR910004378B1 (ko) | 1991-06-26 |
| ES540784A0 (es) | 1986-12-01 |
| ATE38512T1 (de) | 1988-11-15 |
| GR850531B (US06373033-20020416-M00035.png) | 1985-07-01 |
| HUT37117A (en) | 1985-11-28 |
| ZA851567B (en) | 1986-01-29 |
| IE850518L (en) | 1985-09-02 |
| DE3566114D1 (en) | 1988-12-15 |
| EP0153720A3 (en) | 1986-06-11 |
| DK97485A (da) | 1985-09-03 |
| AR241109A2 (es) | 1991-11-15 |
| PT80038A (en) | 1985-04-01 |
| KR850006932A (ko) | 1985-10-25 |
| CN85101425A (zh) | 1987-01-17 |
| ES8701720A1 (es) | 1986-12-01 |
| CA1242452A (en) | 1988-09-27 |
| JPH0254824B2 (US06373033-20020416-M00035.png) | 1990-11-22 |
| JPS60185758A (ja) | 1985-09-21 |
| DK164855C (da) | 1993-01-11 |
| IE57975B1 (en) | 1993-06-02 |
| AR241109A1 (es) | 1991-11-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1004351B (zh) | 带有次苯基的斯柏格埃林有关化合物的制备方法 | |
| CN1003445B (zh) | 噻唑烷二酮衍生物，其制备方法和用途 | |
| CN1003111B (zh) | 胃肠外营养溶液 | |
| CN1004204B (zh) | 以三嗪衍生物为有效成分的除草剂 | |
| CN86103141B (zh) | 表面活性剂组合物、其制备方法及其应用 | |
| CN85108388B (zh) | 一种祛痰剂的制备过程 | |
| CN1004420B (zh) | 防污组合物及其应用 | |
| WO2010120013A1 (ko) | 신규한 로다민 유도체 및 이를 포함한 차아염소산 검출 센서 | |
| WO2020262996A1 (ko) | 신규한 아미노알칸산에 바이페닐기를 도입한 유도체 화합물 및 이를 포함하는 항진균성 약학적 조성물 | |
| CN1004146B (zh) | L-肉毒碱的微生物学制备方法 | |
| AU2019381113A1 (en) | Novel compound as protein kinase inhibitor, and pharmaceutical composition comprising thereof | |
| CN1004205B (zh) | 喹诺酮强心兴奋剂的制备方法 | |
| CN1003179B (zh) | 适于搪瓷涂层的冷轧钢板及制造方法 | |
| CN85101892B (zh) | 制备新型的1，5-苯并硫杂吖庚因衍生物的方法 | |
| WO2013043002A1 (en) | Imide-containing benzothiazole derivative or its salt and pharmaceutical composition comprising the same | |
| CN1004272B (zh) | 吡唑啉杀虫剂 | |
| CN1003471B (zh) | 高分辨率深能级瞬态谱仪的设置方法及仪器 | |
| CN85104392B (zh) | 喹诺酮变力剂的制备方法 | |
| WO2018190452A1 (ko) | 새로운 탠덤 말로네이트 기반의 양친매성 분자 및 이의 활용 | |
| CN85108833B (zh) | 工业用低温柔韧的醚—酰胺共聚物的制备方法 | |
| CN1003156B (zh) | 碳酸化制剂的制备方法 | |
| WO2021075904A1 (ko) | 새로운 트라이아진 기반의 양친매성 화합물 및 이의 활용 | |
| CN1005376B (zh) | 含有5-(2-氯-4-三氟甲基苯氧基)-2-硝基-α-取代的苯乙酮和/或衍生物肟作为有效成分的除草剂以及消灭不需要的杂草的方法 | |
| CN1006069B (zh) | 氨基醇衍生物的制备方法 | |
| CN85103724B (zh) | 制备新型的吡咯并苯并咪唑的方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C13 | Decision | ||
| GR02 | Examined patent application | ||
| CI01 | Publication of corrected invention patent application |
Correction item: Denomination of Invention Correct: Phenylene...... False: Phenylene...... Number: 22 Page: 35 Volume: 5 |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ERR | Gazette correction |
Free format text: CORRECT FROM: INVENTION NAME WITH SUB PHENYL TO: WITH PHENYLENYL |
|
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |