DK164855C - Spergualin-beslaegtede forbindelser med en phenylengruppe, fremgangsmaade til fremstilling deraf samt en farmaceutisk sammensaetning - Google Patents

Spergualin-beslaegtede forbindelser med en phenylengruppe, fremgangsmaade til fremstilling deraf samt en farmaceutisk sammensaetning

Info

Publication number
DK164855C
DK164855C DK097485A DK97485A DK164855C DK 164855 C DK164855 C DK 164855C DK 097485 A DK097485 A DK 097485A DK 97485 A DK97485 A DK 97485A DK 164855 C DK164855 C DK 164855C
Authority
DK
Denmark
Prior art keywords
spergualin
procedures
preparing
pharmaceutical composition
phenylene group
Prior art date
Application number
DK097485A
Other languages
English (en)
Other versions
DK97485D0 (da
DK164855B (da
DK97485A (da
Inventor
Hamao Umezawa
Tomio Takeuchi
Rinzo Nishizawa
Katsutoshi Takahashi
Teruya Nakamura
Yoshihisa Umeda
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of DK97485D0 publication Critical patent/DK97485D0/da
Publication of DK97485A publication Critical patent/DK97485A/da
Publication of DK164855B publication Critical patent/DK164855B/da
Application granted granted Critical
Publication of DK164855C publication Critical patent/DK164855C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK097485A 1984-03-02 1985-03-01 Spergualin-beslaegtede forbindelser med en phenylengruppe, fremgangsmaade til fremstilling deraf samt en farmaceutisk sammensaetning DK164855C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59038615A JPS60185758A (ja) 1984-03-02 1984-03-02 フエニレン基を有するスパガリン関連化合物およびその製造法
JP3861584 1984-03-02

Publications (4)

Publication Number Publication Date
DK97485D0 DK97485D0 (da) 1985-03-01
DK97485A DK97485A (da) 1985-09-03
DK164855B DK164855B (da) 1992-08-31
DK164855C true DK164855C (da) 1993-01-11

Family

ID=12530153

Family Applications (1)

Application Number Title Priority Date Filing Date
DK097485A DK164855C (da) 1984-03-02 1985-03-01 Spergualin-beslaegtede forbindelser med en phenylengruppe, fremgangsmaade til fremstilling deraf samt en farmaceutisk sammensaetning

Country Status (17)

Country Link
US (1) US4556735A (da)
EP (1) EP0153720B1 (da)
JP (1) JPS60185758A (da)
KR (1) KR910004378B1 (da)
CN (1) CN1004351B (da)
AR (1) AR241109A1 (da)
AT (1) ATE38512T1 (da)
AU (1) AU575912B2 (da)
CA (1) CA1242452A (da)
DE (1) DE3566114D1 (da)
DK (1) DK164855C (da)
ES (1) ES8701720A1 (da)
GR (1) GR850531B (da)
HU (1) HU193085B (da)
IE (1) IE57975B1 (da)
PT (1) PT80038B (da)
ZA (1) ZA851567B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129119A (ja) * 1984-11-13 1986-06-17 Microbial Chem Res Found 新規免疫抑制剤
JPS61165322A (ja) * 1985-01-14 1986-07-26 Microbial Chem Res Found スパガリン類の注射用凍結乾燥製剤
JPH0742268B2 (ja) * 1985-08-27 1995-05-10 財団法人微生物化学研究会 フエニレン基を有するスパガリン類縁化合物及びその製造法
JPH075538B2 (ja) * 1985-08-27 1995-01-25 財団法人微生物化学研究会 フエニレン基を有するスパガリン関連ニトリル化合物及びその製造法
DE3770680D1 (de) * 1986-04-04 1991-07-18 Microbial Chem Res Found Spergualinaehnliche verbindungen und ihr herstellungsverfahren.
JP2605762B2 (ja) * 1986-12-10 1997-04-30 武田薬品工業株式会社 δ−ハイドロキシ−β−リジン誘導体およびその製造法
JPH0794424B2 (ja) * 1987-09-30 1995-10-11 財団法人微生物化学研究会 新スパガリン関連化合物およびその製造法
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions
JPH0776204B2 (ja) * 1988-07-01 1995-08-16 寳酒造株式会社 スパガリン類の精製法
US4990536A (en) * 1989-04-03 1991-02-05 Nippon Kayaku Kabushiki Kaisha Immunopotentiator and spergualin-related compound therefor
US5162581A (en) * 1989-05-29 1992-11-10 Takaru Shuzo Co., Ltd. Crystalline deoxyspergualin, process for its preparation and suppository containing the same
DE69104291T2 (de) * 1990-07-20 1995-05-18 Takara Shuzo Co Spergulinähnliche Verbindungen und ihre Verwendung.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5748957A (en) * 1980-09-08 1982-03-20 Microbial Chem Res Found Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient
JPS57185254A (en) * 1981-05-11 1982-11-15 Microbial Chem Res Found Novel carcinostatic substances and their preparation
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found N−〔4−(3−アミノプロピル)アミノブチル〕−2−(ω−グアニジノ脂肪酸アミド)−2−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法

Also Published As

Publication number Publication date
PT80038A (en) 1985-04-01
IE57975B1 (en) 1993-06-02
AU3929685A (en) 1985-09-05
HUT37117A (en) 1985-11-28
CN1004351B (zh) 1989-05-31
DK97485D0 (da) 1985-03-01
IE850518L (en) 1985-09-02
DE3566114D1 (en) 1988-12-15
ES540784A0 (es) 1986-12-01
ES8701720A1 (es) 1986-12-01
DK164855B (da) 1992-08-31
US4556735A (en) 1985-12-03
PT80038B (pt) 1987-09-18
AR241109A1 (es) 1991-11-15
EP0153720B1 (en) 1988-11-09
AU575912B2 (en) 1988-08-11
CN85101425A (zh) 1987-01-17
EP0153720A2 (en) 1985-09-04
CA1242452A (en) 1988-09-27
AR241109A2 (es) 1991-11-15
HU193085B (en) 1987-08-28
KR850006932A (ko) 1985-10-25
KR910004378B1 (ko) 1991-06-26
ZA851567B (en) 1986-01-29
EP0153720A3 (en) 1986-06-11
ATE38512T1 (de) 1988-11-15
GR850531B (da) 1985-07-01
DK97485A (da) 1985-09-03
JPS60185758A (ja) 1985-09-21
JPH0254824B2 (da) 1990-11-22

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