CN100427081C - 作为红细胞生成刺激剂的中链长脂肪酸类、甘油酯类和类似物 - Google Patents

作为红细胞生成刺激剂的中链长脂肪酸类、甘油酯类和类似物 Download PDF

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Publication number
CN100427081C
CN100427081C CNB200480004978XA CN200480004978A CN100427081C CN 100427081 C CN100427081 C CN 100427081C CN B200480004978X A CNB200480004978X A CN B200480004978XA CN 200480004978 A CN200480004978 A CN 200480004978A CN 100427081 C CN100427081 C CN 100427081C
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application
anemia
treatment
chemical compound
cells
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Chinese (zh)
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CN1753665A (zh
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C·宾尼
L·加农
P·劳伦
B·扎克利
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Prometic Biosciences Inc
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Prometic Biosciences Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNB200480004978XA 2003-02-07 2004-02-06 作为红细胞生成刺激剂的中链长脂肪酸类、甘油酯类和类似物 Expired - Fee Related CN100427081C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44545403P 2003-02-07 2003-02-07
US60/445454 2003-02-07

Publications (2)

Publication Number Publication Date
CN1753665A CN1753665A (zh) 2006-03-29
CN100427081C true CN100427081C (zh) 2008-10-22

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CNB200480004978XA Expired - Fee Related CN100427081C (zh) 2003-02-07 2004-02-06 作为红细胞生成刺激剂的中链长脂肪酸类、甘油酯类和类似物

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Country Link
US (1) US9682054B2 (https=)
EP (1) EP1592416B1 (https=)
JP (1) JP5390070B2 (https=)
KR (1) KR101120775B1 (https=)
CN (1) CN100427081C (https=)
AP (1) AP2005003367A0 (https=)
AR (1) AR043120A1 (https=)
AT (1) ATE419846T1 (https=)
AU (1) AU2004210193B2 (https=)
BR (1) BRPI0407276A (https=)
CA (1) CA2515160C (https=)
CY (1) CY1108963T1 (https=)
DE (2) DE04708802T1 (https=)
DK (1) DK1592416T3 (https=)
EA (1) EA009939B1 (https=)
ES (1) ES2255467T3 (https=)
IL (1) IL170057A (https=)
JO (1) JO2705B1 (https=)
MA (1) MA27664A1 (https=)
MX (1) MXPA05008382A (https=)
MY (1) MY140913A (https=)
NO (1) NO334085B1 (https=)
NZ (1) NZ541593A (https=)
PT (1) PT1592416E (https=)
SI (1) SI1592416T1 (https=)
TN (1) TNSN05189A1 (https=)
WO (1) WO2004069237A1 (https=)
ZA (1) ZA200506246B (https=)

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BRPI1010587A2 (pt) 2009-06-08 2019-04-09 Acceleron Pharma Inc. métodos para aumentar adipócitos termogênicos
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KR20180085825A (ko) * 2009-08-13 2018-07-27 악셀레론 파마 인코포레이티드 적혈구 수준을 증가시키기 위한 ｇｄｆ 트랩과 에리트로포이에틴 수용체 활성인자의 병용
JP6267425B2 (ja) 2009-11-17 2018-01-24 アクセルロン ファーマ， インコーポレイテッド 筋ジストロフィー治療のためのユートロフィン誘導に関するａｃｔｒｉｉｂタンパク質およびその改変体およびその使用
CN103298832A (zh) 2010-11-08 2013-09-11 阿塞勒隆制药公司 Actriia结合剂及其用途
TWI572352B (zh) * 2012-03-01 2017-03-01 波麥堤克藥學Ｓｍｔ有限公司 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法
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Also Published As

Publication number Publication date
MA27664A1 (fr) 2005-12-01
JP5390070B2 (ja) 2014-01-15
EA009939B1 (ru) 2008-04-28
IL170057A (en) 2011-09-27
DK1592416T3 (da) 2009-04-20
CN1753665A (zh) 2006-03-29
AP2005003367A0 (en) 2005-09-30
AU2004210193A1 (en) 2004-08-19
DE04708802T1 (de) 2006-06-22
WO2004069237A1 (en) 2004-08-19
CA2515160C (en) 2013-01-08
NZ541593A (en) 2009-05-31
AU2004210193B2 (en) 2007-07-12
EA200501267A1 (ru) 2006-02-24
SI1592416T1 (sl) 2009-06-30
US20060128800A1 (en) 2006-06-15
TNSN05189A1 (en) 2007-06-11
BRPI0407276A (pt) 2006-01-31
CA2515160A1 (en) 2004-08-19
MY140913A (en) 2010-01-29
PT1592416E (pt) 2009-04-03
CY1108963T1 (el) 2014-07-02
KR101120775B1 (ko) 2012-04-18
EP1592416A1 (en) 2005-11-09
JP2006516987A (ja) 2006-07-13
US9682054B2 (en) 2017-06-20
EP1592416B1 (en) 2009-01-07
ES2255467T1 (es) 2006-07-01
NO334085B1 (no) 2013-12-09
DE602004018902D1 (de) 2009-02-26
JO2705B1 (ar) 2014-03-15
NO20053994D0 (no) 2005-08-26
ES2255467T3 (es) 2009-05-01
ZA200506246B (en) 2006-12-27
AR043120A1 (es) 2005-07-20
NO20053994L (no) 2005-10-06
MXPA05008382A (es) 2005-11-04
KR20050118671A (ko) 2005-12-19
ATE419846T1 (de) 2009-01-15

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Denomination of invention: Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis

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