CN100338029C - 2-卤代酰基-3-氨基-丙烯酸-衍生物的制备方法 - Google Patents
2-卤代酰基-3-氨基-丙烯酸-衍生物的制备方法 Download PDFInfo
- Publication number
- CN100338029C CN100338029C CNB02825189XA CN02825189A CN100338029C CN 100338029 C CN100338029 C CN 100338029C CN B02825189X A CNB02825189X A CN B02825189XA CN 02825189 A CN02825189 A CN 02825189A CN 100338029 C CN100338029 C CN 100338029C
- Authority
- CN
- China
- Prior art keywords
- amino
- carboxylic acid
- haloalkyl
- acrylate
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Description
Claims (17)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10161978.2 | 2001-12-17 | ||
DE10161978A DE10161978A1 (de) | 2001-12-17 | 2001-12-17 | Verfahren zur Herstellung von 2-Halogenacyl-3-amino-acrylsäure-derivate |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1604889A CN1604889A (zh) | 2005-04-06 |
CN100338029C true CN100338029C (zh) | 2007-09-19 |
Family
ID=7709546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB02825189XA Expired - Fee Related CN100338029C (zh) | 2001-12-17 | 2002-12-04 | 2-卤代酰基-3-氨基-丙烯酸-衍生物的制备方法 |
Country Status (8)
Country | Link |
---|---|
US (1) | US6706911B1 (zh) |
EP (1) | EP1458670B1 (zh) |
JP (1) | JP4301951B2 (zh) |
CN (1) | CN100338029C (zh) |
AT (1) | ATE501113T1 (zh) |
AU (1) | AU2002363862A1 (zh) |
DE (2) | DE10161978A1 (zh) |
WO (1) | WO2003051820A1 (zh) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9324517D0 (en) * | 1993-11-30 | 1994-01-19 | Octel Chem Ltd | Process for the preparation of substituted 4-hydroxycoumarins |
DE10349500A1 (de) * | 2003-10-23 | 2005-06-02 | Bayer Cropscience Ag | Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern |
KR101077366B1 (ko) | 2006-03-22 | 2011-10-26 | 에프. 호프만-라 로슈 아게 | 11-베타-hsd-1로서의 피라졸 |
DE102006039909A1 (de) * | 2006-08-25 | 2008-03-13 | Bayer Cropscience Ag | Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten |
AU2007340689A1 (en) | 2006-12-28 | 2008-07-10 | Mitsui Chemicals, Inc. | 2-fluorinated acyl-3-aminoacrylonitrile derivative and method for producing the same |
JP5260636B2 (ja) | 2007-05-31 | 2013-08-14 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | ピラゾールを生産するプロセス |
CN101801906A (zh) | 2007-08-16 | 2010-08-11 | 索尔维公司 | 制备4-氟取代的3-氧代-烷酸酯的方法 |
EP2042482A1 (de) * | 2007-09-26 | 2009-04-01 | Bayer CropScience AG | Verfahren zur Herstellung von 2-Dihalogenacyl-3-amino-acrylsäure-Derivaten |
EP2072497A1 (de) | 2007-12-21 | 2009-06-24 | Bayer CropScience AG | Verfahren zum Herstellen von 2-Fluoracyl-3-amino-acrylsäure-Derivaten |
JP5199337B2 (ja) * | 2008-03-18 | 2013-05-15 | 三井化学アグロ株式会社 | 含フッ素アシル酢酸誘導体の製造方法、含フッ素ピラゾールカルボン酸エステル誘導体の製造方法及び含フッ素ピラゾールカルボン酸誘導体の製造方法 |
JP2009227643A (ja) * | 2008-03-25 | 2009-10-08 | Mitsui Chemicals Agro Inc | 含フッ素アルキルカルボン酸誘導体を利用した含フッ素ピラゾール誘導体の製造方法 |
PL2300417T3 (pl) | 2008-05-02 | 2015-12-31 | Basf Se | Sposób wytwarzania estrów kwasu 2-(aminometylideno)-4,4-difluoro-3-oksomasłowego |
EP2297111B1 (de) * | 2008-05-02 | 2012-06-20 | Basf Se | Verfahren zur herstellung halogensubstituierter 2-(aminomethyliden)-3-oxobuttersäureester |
MX2010011433A (es) | 2008-05-05 | 2010-11-12 | Basf Se | Procedimiento para la preparacion de compuestos pirazolicos sustituidos en posiciones 1,3,4. |
JP5558467B2 (ja) | 2008-07-21 | 2014-07-23 | ビーエーエスエフ ソシエタス・ヨーロピア | 1,3−二置換ピラゾールカルボン酸エステルの調製方法 |
JP5228817B2 (ja) * | 2008-11-12 | 2013-07-03 | セントラル硝子株式会社 | ピラゾール化合物の製造方法 |
TWI518084B (zh) * | 2009-03-26 | 2016-01-21 | 鹽野義製藥股份有限公司 | 哌喃酮與吡啶酮衍生物之製造方法 |
US8362273B2 (en) | 2009-11-05 | 2013-01-29 | Basf Se | Process for preparing aminale and their use for preparing 1,3-disubstituted pyrazole compounds |
WO2011054732A1 (en) | 2009-11-05 | 2011-05-12 | Basf Se | Process for preparing 1,3-disubstituted pyrazole compounds |
GB201004299D0 (en) * | 2010-03-15 | 2010-04-28 | Syngenta Participations Ag | Process |
JP5830957B2 (ja) * | 2011-06-22 | 2015-12-09 | セントラル硝子株式会社 | ピラゾール化合物の製造方法 |
WO2012176717A1 (ja) * | 2011-06-22 | 2012-12-27 | セントラル硝子株式会社 | ピラゾール化合物の製造方法 |
JP5915004B2 (ja) * | 2011-06-22 | 2016-05-11 | セントラル硝子株式会社 | ピラゾール化合物の製造方法 |
JP5793983B2 (ja) * | 2011-06-22 | 2015-10-14 | セントラル硝子株式会社 | ピラゾール化合物の製造方法 |
ES2672581T3 (es) * | 2014-06-11 | 2018-06-15 | Bayer Cropscience Aktiengesellschaft | Proceso para la preparación de 3,5-bis(haloalquil)pirazoles por medio de la acilación de cetiminas |
CN106458917B (zh) | 2014-06-11 | 2019-04-12 | 拜耳作物科学股份公司 | 通过腙的酰化制备3,5-双(卤代烷基)吡唑衍生物的方法 |
CN104529899A (zh) * | 2014-12-19 | 2015-04-22 | 浙江泰达作物科技有限公司 | 高区域选择性制备1-烷基-3-卤代烷基吡唑衍生物的方法 |
CN105541716B (zh) * | 2015-03-26 | 2024-02-23 | Agc株式会社 | 吡唑衍生物的制造方法 |
EP3178813A1 (en) | 2015-12-09 | 2017-06-14 | Basf Se | Method for preparing halogenated 3-oxocarboxylates carrying a 2-alkoxymethylidene or a 2-dialkylaminomethylidene group |
CN111372908A (zh) | 2017-09-04 | 2020-07-03 | 索尔维公司 | 用于制造二氟乙酰氯的方法和中间体 |
PT3797099T (pt) * | 2018-05-21 | 2024-02-05 | Pi Industries Ltd | Método para preparar compostos heterocíclicos substituídos |
EP3807249A1 (en) | 2018-06-18 | 2021-04-21 | Bayer Aktiengesellschaft | Disubstituted 3-pyrazole carboxylates and a process for their preparation via acylation of enolates |
CN110577503A (zh) * | 2019-08-02 | 2019-12-17 | 宿迁市科莱博生物化学有限公司 | 一种卤素取代化合物及其制备方法和应用 |
CN111307962B (zh) * | 2019-12-03 | 2022-07-08 | 珠海润都制药股份有限公司 | 一种盐酸莫西沙星中3-二甲氨基丙烯酸乙酯的检测方法 |
CN111362874B (zh) * | 2020-03-16 | 2021-06-29 | 徐州圣元化工有限公司 | 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的制备方法 |
CN112480007B (zh) * | 2020-12-08 | 2022-11-18 | 宿迁市科莱博生物化学有限公司 | 一种1,3-二甲基-1h-吡唑-4-羧酸的合成方法 |
CN115403524A (zh) * | 2021-05-26 | 2022-11-29 | 浙江省化工研究院有限公司 | 3-氟代吡唑羧酸酯、3-氟代烷基-1-取代吡唑-4-羧酸的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4868198A (en) * | 1987-04-10 | 1989-09-19 | Bayer Aktiengesellschaft | 3-halogenoalkyl-1-aryl-pyrazole pesticides, compositions and use |
EP1132375A1 (en) * | 1998-11-18 | 2001-09-12 | Asahi Glass Company Ltd. | Aminoacrylic acid derivatives and process for producing the same |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2578788A (en) * | 1949-05-13 | 1951-12-18 | Rohm & Haas | Preparation of beta-tertiary aminoacrylic esters from alkoxyacrylic esters |
DE4302156A1 (de) | 1993-01-27 | 1994-07-28 | Bayer Ag | Verfahren zur Herstellung von Aminomethylenverbindungen |
KR20000035081A (ko) | 1998-11-10 | 2000-06-26 | 마크 에스. 아들러 | 2-(트리할로아세틸)-3-(치환된 아미노)-2-프로페노에이트 제조방법 |
-
2001
- 2001-12-17 DE DE10161978A patent/DE10161978A1/de not_active Withdrawn
-
2002
- 2002-12-04 EP EP02798321A patent/EP1458670B1/de not_active Expired - Lifetime
- 2002-12-04 AU AU2002363862A patent/AU2002363862A1/en not_active Abandoned
- 2002-12-04 DE DE50214951T patent/DE50214951D1/de not_active Expired - Lifetime
- 2002-12-04 WO PCT/EP2002/013721 patent/WO2003051820A1/de active Application Filing
- 2002-12-04 CN CNB02825189XA patent/CN100338029C/zh not_active Expired - Fee Related
- 2002-12-04 JP JP2003552708A patent/JP4301951B2/ja not_active Expired - Fee Related
- 2002-12-04 AT AT02798321T patent/ATE501113T1/de active
- 2002-12-13 US US10/319,242 patent/US6706911B1/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4868198A (en) * | 1987-04-10 | 1989-09-19 | Bayer Aktiengesellschaft | 3-halogenoalkyl-1-aryl-pyrazole pesticides, compositions and use |
EP1132375A1 (en) * | 1998-11-18 | 2001-09-12 | Asahi Glass Company Ltd. | Aminoacrylic acid derivatives and process for producing the same |
Also Published As
Publication number | Publication date |
---|---|
DE50214951D1 (de) | 2011-04-21 |
EP1458670B1 (de) | 2011-03-09 |
ATE501113T1 (de) | 2011-03-15 |
AU2002363862A1 (en) | 2003-06-30 |
JP4301951B2 (ja) | 2009-07-22 |
EP1458670A1 (de) | 2004-09-22 |
CN1604889A (zh) | 2005-04-06 |
JP2005511782A (ja) | 2005-04-28 |
DE10161978A1 (de) | 2003-06-26 |
US6706911B1 (en) | 2004-03-16 |
WO2003051820A1 (de) | 2003-06-26 |
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Legal Events
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: SALTIGO GMBH Free format text: FORMER OWNER: LANXESS DEUTSCHLAND GMBH Effective date: 20081017 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20081017 Address after: Germany Langenfeld Patentee after: Saltigo GmbH Address before: Germany Leverkusen Patentee before: Lanxess Deutschland GmbH |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20070919 Termination date: 20131204 |